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The map label for this gene is xerC

Identifier: 182681291

GI number: 182681291

Start: 865876

End: 866760

Strand: Direct

Name: xerC

Synonym: XfasM23_0736

Alternate gene names: 182681291

Gene position: 865876-866760 (Clockwise)

Preceding gene: 182681290

Following gene: 182681292

Centisome position: 34.15

GC content: 55.03

Gene sequence:

>885_bases
ATGAGTAGGTTGGTTGAAGATTTCTTCGCTTTCTTGCATGTGGAGCGGGGTATGTCATCGCATACCTTGGATGCTTACCG
GCGTGATATCGGTGCGCTCATTGCCTGGGGGGGGCAACAGGCAGTGGGTGAGGTTGTTGCGCTGGATAGGGCGCAGTTGC
AGGCTTTCGTTTCTGCTGAGCACCGTCGTGGTTTGTCGGCCAAGAGTCTGCAGCGGCGTTTGTCGGCGTGCCGTGGTTTT
TATACATGGTTAGTGAAACGTGGCCACATTGCTGTCAATCCGGCTGCTGGGCTGCGTGCTCCGAAGGCACTGCGTAAGCT
GCCACGCATATTGGATGCGGATGAAGCGGTCTCTTTTGTTCAGATCCCAACGGATACGCCGCTTGGATTGCGTGATCGTG
CGCTATTAGAGTTGTTTTATTCTTCTGGCTTGCGCTTGAGTGAGTTGTGCGGATTGCGTTGGGATGGGTTGGATCTGGAT
GCTGGTTTGGTGAGCGTGTTGGGCAAGGGTAGTCGTCAGCGTGTGGTGCCTGTCGGTTCATATGCGTTGTCTGCGCTTCG
TGAATGGTGTGCTAGTAGTGGTGGTGGAGCGCAACAGCCGGTGTTCCCTGGACGTTACGGTGGACCGATTTCTGCGCGTG
CTGTTCAGGTGCGGATTAAGCAGTTGGCTCAGCGTCAGGGTATGGCCAAGCACGTGCATCCGCATATGTTGCGCCATAGT
TTTGCCAGTCATTTGCTTGAGTCGTCCGGTGATTTGCGTGGTGTGCAGGAGTTGTTAGGCCATGCGGACATTACGACGAC
CCAGATCTACACTCATTTGGATTTTCAGTACCTTTCCAAGGTTTATGACGCTGCGCATCCGCGTGCGCGGCGTAAGGCGC
GCTGA

Upstream 100 bases:

>100_bases
ATCCGGGGATGGGGACGTTGTTTCTACGTATGATGGGGCAGGCGTTGTTCGATGCGCTAAAGCGTTTCGATGTCTGACAT
GGCTACCGCAGCGAGAGAGT

Downstream 100 bases:

>100_bases
GTGTGTGGGTGTGTGCTGTATTTCTTAGGCATTATCAACAGTGTGTTGTATGGGTAGGTGAATCAATCAGCCCTGAGGGG
CATGGATGAATGTCATTTGG

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSRLVEDFFAFLHVERGMSSHTLDAYRRDIGALIAWGGQQAVGEVVALDRAQLQAFVSAEHRRGLSAKSLQRRLSACRGF
YTWLVKRGHIAVNPAAGLRAPKALRKLPRILDADEAVSFVQIPTDTPLGLRDRALLELFYSSGLRLSELCGLRWDGLDLD
AGLVSVLGKGSRQRVVPVGSYALSALREWCASSGGGAQQPVFPGRYGGPISARAVQVRIKQLAQRQGMAKHVHPHMLRHS
FASHLLESSGDLRGVQELLGHADITTTQIYTHLDFQYLSKVYDAAHPRARRKAR

Sequences:

>Translated_294_residues
MSRLVEDFFAFLHVERGMSSHTLDAYRRDIGALIAWGGQQAVGEVVALDRAQLQAFVSAEHRRGLSAKSLQRRLSACRGF
YTWLVKRGHIAVNPAAGLRAPKALRKLPRILDADEAVSFVQIPTDTPLGLRDRALLELFYSSGLRLSELCGLRWDGLDLD
AGLVSVLGKGSRQRVVPVGSYALSALREWCASSGGGAQQPVFPGRYGGPISARAVQVRIKQLAQRQGMAKHVHPHMLRHS
FASHLLESSGDLRGVQELLGHADITTTQIYTHLDFQYLSKVYDAAHPRARRKAR
>Mature_293_residues
SRLVEDFFAFLHVERGMSSHTLDAYRRDIGALIAWGGQQAVGEVVALDRAQLQAFVSAEHRRGLSAKSLQRRLSACRGFY
TWLVKRGHIAVNPAAGLRAPKALRKLPRILDADEAVSFVQIPTDTPLGLRDRALLELFYSSGLRLSELCGLRWDGLDLDA
GLVSVLGKGSRQRVVPVGSYALSALREWCASSGGGAQQPVFPGRYGGPISARAVQVRIKQLAQRQGMAKHVHPHMLRHSF
ASHLLESSGDLRGVQELLGHADITTTQIYTHLDFQYLSKVYDAAHPRARRKAR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=289, Percent_Identity=48.4429065743945, Blast_Score=275, Evalue=2e-75,
Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=36.734693877551, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1790767, Length=194, Percent_Identity=30.4123711340206, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=30.3571428571429, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_XYLF2 (B2IA18)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829451.1
- ProteinModelPortal:   B2IA18
- SMR:   B2IA18
- GeneID:   6202966
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0736
- HOGENOM:   HBG727654
- OMA:   YLQVERQ
- ProtClustDB:   PRK00236
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 32435; Mature: 32304

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: NA

Important sites: ACT_SITE 145-145 ACT_SITE 169-169 ACT_SITE 235-235 ACT_SITE 238-238 ACT_SITE 261-261 ACT_SITE 270-270

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLVEDFFAFLHVERGMSSHTLDAYRRDIGALIAWGGQQAVGEVVALDRAQLQAFVSAE
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
HRRGLSAKSLQRRLSACRGFYTWLVKRGHIAVNPAAGLRAPKALRKLPRILDADEAVSFV
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHCCCCHHHHHHHHHHHCHHHCCEEE
QIPTDTPLGLRDRALLELFYSSGLRLSELCGLRWDGLDLDAGLVSVLGKGSRQRVVPVGS
ECCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCEEEECHH
YALSALREWCASSGGGAQQPVFPGRYGGPISARAVQVRIKQLAQRQGMAKHVHPHMLRHS
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FASHLLESSGDLRGVQELLGHADITTTQIYTHLDFQYLSKVYDAAHPRARRKAR
HHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
SRLVEDFFAFLHVERGMSSHTLDAYRRDIGALIAWGGQQAVGEVVALDRAQLQAFVSAE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
HRRGLSAKSLQRRLSACRGFYTWLVKRGHIAVNPAAGLRAPKALRKLPRILDADEAVSFV
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHCCCCHHHHHHHHHHHCHHHCCEEE
QIPTDTPLGLRDRALLELFYSSGLRLSELCGLRWDGLDLDAGLVSVLGKGSRQRVVPVGS
ECCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCEEEECHH
YALSALREWCASSGGGAQQPVFPGRYGGPISARAVQVRIKQLAQRQGMAKHVHPHMLRHS
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FASHLLESSGDLRGVQELLGHADITTTQIYTHLDFQYLSKVYDAAHPRARRKAR
HHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA