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The map label for this gene is cobP [H]

Identifier: 182680495

GI number: 182680495

Start: 4075575

End: 4076138

Strand: Reverse

Name: cobP [H]

Synonym: Bind_3597

Alternate gene names: 182680495

Gene position: 4076138-4075575 (Counterclockwise)

Preceding gene: 182680496

Following gene: 182680490

Centisome position: 97.75

GC content: 59.57

Gene sequence:

>564_bases
ATGAATCCCTTCCCGGCCTCTCCCATCCGCAGTCTGTTTATTCTCGGCGGCGCACGCTCCGGCAAGAGTTTTTACGCACA
AAGACTGGCAGAAACCTCCGGCTTGCGGCCGGTGATGATCGCCACGGCCGAGGCCCATGATGCGGAAATGGCCGAACGCA
TAGCCCGCCACAAGAGTGAACGCGGTCCCCTCTGGGGGCTTGTCGAAACGCCTCTCGCTCTGTGTGAAACCCTTGAGCAG
AACGCCCATCCCGCCTCCATTCTGCTCGTGGATTGCGCGACGCTCTGGCTCAGCAATCTGTTTTTCCATGAAGCCGAAAT
CGACACAGCCGTTGCCAATCTCACGGCCACGATTCTCAAACTGTCAGGCCCCTTGATCATTGTCTCCAATGAGGTCGGCC
AGGGCATTGTCCCGGACAATGCCCTGGCGCGAAAGTTTCGTGATGCGCAAGGCCGGCTCAATCAGGCTCTTGCGCAAGTC
TGCGAGGGTGTCGTCCTGGTCAGCGCTGGACTGCCGCTTACACTCAAACCCGCTCCCCAACCCGCACCTCTCTGGCGCTT
TTGA

Upstream 100 bases:

>100_bases
TCTGCGAACGCACCGATTGTCCGCAACGGGCAGCGCCGCCGATCGATCGCGGCCTTCTCGTCGATCCGGACCGCCGCGAT
TTCGTTCCTTTCCGGTTTAC

Downstream 100 bases:

>100_bases
GAAGGCGGAAACCTTATGTTTGATCACACCTAAAATAATAACAAGCTCACCATCATTTCAGTAATCAGCAGCAATTCATA
ATGTGAAGGTCCGGCTTACC

Product: cobalbumin biosynthesis protein

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNPFPASPIRSLFILGGARSGKSFYAQRLAETSGLRPVMIATAEAHDAEMAERIARHKSERGPLWGLVETPLALCETLEQ
NAHPASILLVDCATLWLSNLFFHEAEIDTAVANLTATILKLSGPLIIVSNEVGQGIVPDNALARKFRDAQGRLNQALAQV
CEGVVLVSAGLPLTLKPAPQPAPLWRF

Sequences:

>Translated_187_residues
MNPFPASPIRSLFILGGARSGKSFYAQRLAETSGLRPVMIATAEAHDAEMAERIARHKSERGPLWGLVETPLALCETLEQ
NAHPASILLVDCATLWLSNLFFHEAEIDTAVANLTATILKLSGPLIIVSNEVGQGIVPDNALARKFRDAQGRLNQALAQV
CEGVVLVSAGLPLTLKPAPQPAPLWRF
>Mature_187_residues
MNPFPASPIRSLFILGGARSGKSFYAQRLAETSGLRPVMIATAEAHDAEMAERIARHKSERGPLWGLVETPLALCETLEQ
NAHPASILLVDCATLWLSNLFFHEAEIDTAVANLTATILKLSGPLIIVSNEVGQGIVPDNALARKFRDAQGRLNQALAQV
CEGVVLVSAGLPLTLKPAPQPAPLWRF

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=180, Percent_Identity=35.5555555555556, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20126; Mature: 20126

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFPASPIRSLFILGGARSGKSFYAQRLAETSGLRPVMIATAEAHDAEMAERIARHKSE
CCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCC
RGPLWGLVETPLALCETLEQNAHPASILLVDCATLWLSNLFFHEAEIDTAVANLTATILK
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGPLIIVSNEVGQGIVPDNALARKFRDAQGRLNQALAQVCEGVVLVSAGLPLTLKPAPQ
HCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCC
PAPLWRF
CCCCCCC
>Mature Secondary Structure
MNPFPASPIRSLFILGGARSGKSFYAQRLAETSGLRPVMIATAEAHDAEMAERIARHKSE
CCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCC
RGPLWGLVETPLALCETLEQNAHPASILLVDCATLWLSNLFFHEAEIDTAVANLTATILK
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGPLIIVSNEVGQGIVPDNALARKFRDAQGRLNQALAQVCEGVVLVSAGLPLTLKPAPQ
HCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCC
PAPLWRF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]