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The map label for this gene is nadA2 [H]

Identifier: 182680394

GI number: 182680394

Start: 3971369

End: 3972400

Strand: Reverse

Name: nadA2 [H]

Synonym: Bind_3494

Alternate gene names: 182680394

Gene position: 3972400-3971369 (Counterclockwise)

Preceding gene: 182680395

Following gene: 182680393

Centisome position: 95.26

GC content: 59.4

Gene sequence:

>1032_bases
ATGGAGCGGCAGGACGCCGCCGTGCCGGAACTGCTGTTACATGGTCTCGAATCGCCCGAGGCCCGTGATCTTCCGGCGCG
TGATCTCTATGCGAAGCTCCGCCATACGATTCCCGCGTTCGAATGGCCTGTTTACGCGCAAGAGATTGACGCCATTATGA
CGTTGAAGGAACGGCGCAATGCCGTCGTGCTCGCGCATAATTACCAGACGCCGGATATTTACCATTGCGTCTCTGATCTC
GTCGGAGACAGTCTCGCCTTGGCGCGCGAGGCGATGAACGTCGAGGCTGATGTCATTGTGCTGGCCGGCGTGCATTTCAT
GGCTGAGACGGCGAAACTTCTCAATCCGGAGAAAACCGTCCTTATTCCCGATCTCGGCGCCGGCTGCTCCTTGGCCGAAT
CAATCACGCCCGAAGATGTGCGCGCCTTGCGCCGCCGCTATCCCGGCGTGCCGATTGTCACTTATGTGAACACCTCGGCC
GCCGTGAAGGCCGAATCGGACATTTGCTGCACCTCCGGCAATGCCAAGGCTGTGGTGGAATCTTTGGGCGTGCCGCGCGT
CATCATGATCCCGGACGAATATCTGGCGCAGAATATTGCCGCCGAGACGGGCGTCGAGATCATCACCTGGAAAGGCCATT
GCGAGGTGCATGAGCGCTTCGAGCCCGAGGATATCCGGCAATTGCGCGAGGATTATCCTGGTGTGACGGTGCTTGCTCAT
CCCGAATGCCCGCCCGAGGTCGTGAAGGAAGCCGATTTTTCCGGTTCGACCGCGATGATGTCGGCCTATGTCGCACGCGA
GAAGCCGCAGCGCGTCGTGCTCCTGACGGAATGTTCGATGAGCGATAATGTCGCGGTCCATCACCCGGATCTCGAATTCA
TTCGTCCCTGCAATCTCTGCCCGCATATGAAGAAAATCACCTTGGGCAACATCCGCCATGCGCTGGAGACGATGACGCAT
GAAGTGACGATCGACCCGGAAGTGGCCGGGCGGGCGCGTCTTGCCGTCGAGCGCATGCTGGCCGTGAAATGA

Upstream 100 bases:

>100_bases
AGCATATGGTCCTATAATACTCAAAGGGAGTATAAGGATGGGCTTGAGGATGGATATGGCCCCAGAGACGCTCGATGCGG
CCCTGGATGTGACGATTTCT

Downstream 100 bases:

>100_bases
CCCAGTCCCGGATGACCGAATTTCACGATGTCGGGGGCGCACCGATCATCATCGGCGGCGGCATTGCGGGGCTGATGACG
GCGCTGACACTGGCGCCGCG

Product: quinolinate synthetase complex subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MERQDAAVPELLLHGLESPEARDLPARDLYAKLRHTIPAFEWPVYAQEIDAIMTLKERRNAVVLAHNYQTPDIYHCVSDL
VGDSLALAREAMNVEADVIVLAGVHFMAETAKLLNPEKTVLIPDLGAGCSLAESITPEDVRALRRRYPGVPIVTYVNTSA
AVKAESDICCTSGNAKAVVESLGVPRVIMIPDEYLAQNIAAETGVEIITWKGHCEVHERFEPEDIRQLREDYPGVTVLAH
PECPPEVVKEADFSGSTAMMSAYVAREKPQRVVLLTECSMSDNVAVHHPDLEFIRPCNLCPHMKKITLGNIRHALETMTH
EVTIDPEVAGRARLAVERMLAVK

Sequences:

>Translated_343_residues
MERQDAAVPELLLHGLESPEARDLPARDLYAKLRHTIPAFEWPVYAQEIDAIMTLKERRNAVVLAHNYQTPDIYHCVSDL
VGDSLALAREAMNVEADVIVLAGVHFMAETAKLLNPEKTVLIPDLGAGCSLAESITPEDVRALRRRYPGVPIVTYVNTSA
AVKAESDICCTSGNAKAVVESLGVPRVIMIPDEYLAQNIAAETGVEIITWKGHCEVHERFEPEDIRQLREDYPGVTVLAH
PECPPEVVKEADFSGSTAMMSAYVAREKPQRVVLLTECSMSDNVAVHHPDLEFIRPCNLCPHMKKITLGNIRHALETMTH
EVTIDPEVAGRARLAVERMLAVK
>Mature_343_residues
MERQDAAVPELLLHGLESPEARDLPARDLYAKLRHTIPAFEWPVYAQEIDAIMTLKERRNAVVLAHNYQTPDIYHCVSDL
VGDSLALAREAMNVEADVIVLAGVHFMAETAKLLNPEKTVLIPDLGAGCSLAESITPEDVRALRRRYPGVPIVTYVNTSA
AVKAESDICCTSGNAKAVVESLGVPRVIMIPDEYLAQNIAAETGVEIITWKGHCEVHERFEPEDIRQLREDYPGVTVLAH
PECPPEVVKEADFSGSTAMMSAYVAREKPQRVVLLTECSMSDNVAVHHPDLEFIRPCNLCPHMKKITLGNIRHALETMTH
EVTIDPEVAGRARLAVERMLAVK

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=310, Percent_Identity=36.4516129032258, Blast_Score=177, Evalue=8e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37937; Mature: 37937

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERQDAAVPELLLHGLESPEARDLPARDLYAKLRHTIPAFEWPVYAQEIDAIMTLKERRN
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
AVVLAHNYQTPDIYHCVSDLVGDSLALAREAMNVEADVIVLAGVHFMAETAKLLNPEKTV
EEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCEE
LIPDLGAGCSLAESITPEDVRALRRRYPGVPIVTYVNTSAAVKAESDICCTSGNAKAVVE
EECCCCCCCCHHHCCCHHHHHHHHHHCCCCCEEEEECCCCEEECCCCEEEECCCHHHHHH
SLGVPRVIMIPDEYLAQNIAAETGVEIITWKGHCEVHERFEPEDIRQLREDYPGVTVLAH
HCCCCEEEECCHHHHHHHHHHHCCCEEEEECCCCCHHCCCCHHHHHHHHHHCCCEEEEEC
PECPPEVVKEADFSGSTAMMSAYVAREKPQRVVLLTECSMSDNVAVHHPDLEFIRPCNLC
CCCCHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCHHHCCCCCCC
PHMKKITLGNIRHALETMTHEVTIDPEVAGRARLAVERMLAVK
CCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MERQDAAVPELLLHGLESPEARDLPARDLYAKLRHTIPAFEWPVYAQEIDAIMTLKERRN
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
AVVLAHNYQTPDIYHCVSDLVGDSLALAREAMNVEADVIVLAGVHFMAETAKLLNPEKTV
EEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCEE
LIPDLGAGCSLAESITPEDVRALRRRYPGVPIVTYVNTSAAVKAESDICCTSGNAKAVVE
EECCCCCCCCHHHCCCHHHHHHHHHHCCCCCEEEEECCCCEEECCCCEEEECCCHHHHHH
SLGVPRVIMIPDEYLAQNIAAETGVEIITWKGHCEVHERFEPEDIRQLREDYPGVTVLAH
HCCCCEEEECCHHHHHHHHHHHCCCEEEEECCCCCHHCCCCHHHHHHHHHHCCCEEEEEC
PECPPEVVKEADFSGSTAMMSAYVAREKPQRVVLLTECSMSDNVAVHHPDLEFIRPCNLC
CCCCHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCHHHCCCCCCC
PHMKKITLGNIRHALETMTHEVTIDPEVAGRARLAVERMLAVK
CCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]