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The map label for this gene is rnr [H]

Identifier: 182680316

GI number: 182680316

Start: 3875299

End: 3877674

Strand: Reverse

Name: rnr [H]

Synonym: Bind_3416

Alternate gene names: 182680316

Gene position: 3877674-3875299 (Counterclockwise)

Preceding gene: 182680317

Following gene: 182680315

Centisome position: 92.99

GC content: 61.03

Gene sequence:

>2376_bases
GTGAGGAAAACAGCTGTGCCTCCCTCTTATACCGCCTCCGATGCGGAGACCTCGCCGGGCGCGGGACGCCTGCCGTCGCG
CGCCGATCTTATCGCCTTTATCGCGCGTGAGCGCGAAGCGCAGGGCGATAAAGTACCGGCCAAGATTGGCAAACGGGAAA
TCGCCCGTGCCTTCGATATCAAGGGGGATGATCGCATCGCCCTGAAGCGAATGTTGCGAGAACTCGAAGCGGAGGGCGCG
ATCGAGCGGCGACGCCGCGTGCTGCACCAGCCGGGACGCCTGCCCGCGGTGGTTCTCGCCGAGATCTTTTCCCGCGACCG
CGATGGTGATCTTCTGGCAAGCCCGGTCGAATGGGATGCCTCGCTCGGCCCAATACCCAAAATCGCTATATCGGCGCCGC
GCAAGCCGCGCGCCAATATGCCAGCTCCAGGTCTTGGCGATCGCGCCCTGGTGCGGGTCGAGGCGGTTCCTGATCCAGCA
CCCCATGAGCCTACCTATACCGGCCGCCTGATCAAGCTTCTGCCACGCGCCAGAACACAAGTGCTCGGCCTCTTCCGAGC
CGATCCGCTGGGCGGTGGTGGCCGTATCGTGCCGATTGATAAAAAGAGTCTCGGCCGGGGCGAATTACAGGTTTCCGAGG
CCGATCGCGGTGAGGCGGAGGATGGTGATCTCGTTGCCGTCGAGCCGCTGCGCTCGGGCCGTCTTGGCTTGCCGAGCGCG
CGCGTGCGCGAAAGAATCGGCGCCTTTTCCTCGGAAAAAGCGGTGAGCCTGATCGCTATTCACGCGCATGGCCTGCCGCA
TATTTTCCCGTCCGAAGTGCTGGCGGAAGCCGAAAGCAAAAAGAATGTTGGCCTTGCAGGGCGCGAGGATTGGCGCGAAC
TGCCGTTGGTGACCATCGATCCTCCAGATGCCAAGGATCATGACGACGCCGTTTATGCTGACTATGATCCTGATCCCGCC
AATGTGGGCGGCACGATTTTGAGTGTCGCCATCGCCGATGTCGCCGCTTATGTCCGCCTTGGCGGGGCGCTTGACAAGGA
AGCGCAGGAGCGCGGCAATTCGGTCTATTTTCCCGATCGCGTCGTTCCCATGTTGCCCGAGCGGATTTCCAACGATCTGT
GTTCGTTGCGTCCCGGCGAGGATCGGCCAGCGCTCGCCGTGCGCATGGTCATCGCCGCCGATGGGCACAAGCTTAGCCAC
ACCTTTCATCGCGTAATAATGCGCTCGGCGGCGAAATTGTCTTATGCGCAGGCGCAGGCCGCGATCGATGGCGCGCCTGA
TGATGTGACAGAGCCTTTGCTCGAAACGGTCTTGCGGCCTCTGTATGCGGCGCATGAATGTTTGAAAAAGGCACGCGCCA
AGCGAGGGCCACTCGATCTCGATCTGCCGGAACGCAAGATCAAACTCGATGAGGCTGGTCGCGTCGAACGGATTTTTACC
CCCGCCCGGCTCGATGCGCATAAATTGATCGAGGAATTCATGATCCTCGCCAATGTATGCGCGGCGGAAACGCTGGAGGC
GCATCATCAGCCTTTGATCTATCGCACACATGACGAGCCGACGATCGAAAAGCTCAACGCGCTCGCCGAATTTCTGCATA
CGATCGATATCAAGCTCGCCAAGGGCCAGGTGCTGCGGCCGGCGCAATTCAATGGTATTCTGGCGCAGGTGCGCGAAACC
GAGCACGAACATCTCGTCAACGAGATCGTGTTGCGCACGCAGGCCCAGGCGGAATATGTTACTGAAAATTACGGGCATTT
CGGTCTCAATCTGCGCCGTTACGCGCATTTCACCTCGCCGATTCGCCGCTATGCCGATCTCATCGTGCATCGCGCCCTGA
TCAGCGCCCTGAAATTCGGCTCCGATGGCTTGCCGAATACGGATCCGCATGTTCTTGCCGAAATCGCGGCCAAGATTTCA
GCGGCTGAACGCCGTGCCATGGCCGCCGAGCGCGAGACCGTGGAACGGCTGATCGCCATTCACCTCGCTGATCAAGTCGG
CGCGCAATTCGAGGGCCGCATTTCCGGCGTCACCAAATCCGGCCTGTTCATCCGCCTCATGGACTCAGGGGCCGATGGTT
TCGTGCCCATATCGAGCCTTGCTCAGGATTATTTCCGGCATGATGAAGCAAGGCACGCCTTGATCGGGTCGCGCACCGGC
CTCATGCATCGGCTGGGTGATCTCGTCACCGTCCGGCTCGTCGAGGCAGCGCCGCTGGCAGGCGCGCTGCGTTTCGAACT
CATCGACGGCGGCGCTCTTGCGCCACGCTCGAAAGGCCGGAATGGGTCCGCCAAGGGATCTGCGAAGCGCAGCTTCGACC
CCAAAGCGGAAGAGGCTTTAGCCAAGAAAAACATCAAACGCAGCCGCCGGCGCTGA

Upstream 100 bases:

>100_bases
GCCAAAGCGGCGAAATCATCGGAGCCGGATGAAGAACCCCCTTTTTAAAGTCTTAGAGTGAAGATCAATCTCGGGCTTGG
AGGGATTTAAGGACACGCGC

Downstream 100 bases:

>100_bases
CCGTTTTTTCTCCTTCCTTTCCCACGAGCCTTTCAAGAGACGTCCCACCATGCCGCGCCTAACCCTGGCGATCGAATCTT
TCCCCCTGGCCAGTCGTTTC

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MRKTAVPPSYTASDAETSPGAGRLPSRADLIAFIAREREAQGDKVPAKIGKREIARAFDIKGDDRIALKRMLRELEAEGA
IERRRRVLHQPGRLPAVVLAEIFSRDRDGDLLASPVEWDASLGPIPKIAISAPRKPRANMPAPGLGDRALVRVEAVPDPA
PHEPTYTGRLIKLLPRARTQVLGLFRADPLGGGGRIVPIDKKSLGRGELQVSEADRGEAEDGDLVAVEPLRSGRLGLPSA
RVRERIGAFSSEKAVSLIAIHAHGLPHIFPSEVLAEAESKKNVGLAGREDWRELPLVTIDPPDAKDHDDAVYADYDPDPA
NVGGTILSVAIADVAAYVRLGGALDKEAQERGNSVYFPDRVVPMLPERISNDLCSLRPGEDRPALAVRMVIAADGHKLSH
TFHRVIMRSAAKLSYAQAQAAIDGAPDDVTEPLLETVLRPLYAAHECLKKARAKRGPLDLDLPERKIKLDEAGRVERIFT
PARLDAHKLIEEFMILANVCAAETLEAHHQPLIYRTHDEPTIEKLNALAEFLHTIDIKLAKGQVLRPAQFNGILAQVRET
EHEHLVNEIVLRTQAQAEYVTENYGHFGLNLRRYAHFTSPIRRYADLIVHRALISALKFGSDGLPNTDPHVLAEIAAKIS
AAERRAMAAERETVERLIAIHLADQVGAQFEGRISGVTKSGLFIRLMDSGADGFVPISSLAQDYFRHDEARHALIGSRTG
LMHRLGDLVTVRLVEAAPLAGALRFELIDGGALAPRSKGRNGSAKGSAKRSFDPKAEEALAKKNIKRSRRR

Sequences:

>Translated_791_residues
MRKTAVPPSYTASDAETSPGAGRLPSRADLIAFIAREREAQGDKVPAKIGKREIARAFDIKGDDRIALKRMLRELEAEGA
IERRRRVLHQPGRLPAVVLAEIFSRDRDGDLLASPVEWDASLGPIPKIAISAPRKPRANMPAPGLGDRALVRVEAVPDPA
PHEPTYTGRLIKLLPRARTQVLGLFRADPLGGGGRIVPIDKKSLGRGELQVSEADRGEAEDGDLVAVEPLRSGRLGLPSA
RVRERIGAFSSEKAVSLIAIHAHGLPHIFPSEVLAEAESKKNVGLAGREDWRELPLVTIDPPDAKDHDDAVYADYDPDPA
NVGGTILSVAIADVAAYVRLGGALDKEAQERGNSVYFPDRVVPMLPERISNDLCSLRPGEDRPALAVRMVIAADGHKLSH
TFHRVIMRSAAKLSYAQAQAAIDGAPDDVTEPLLETVLRPLYAAHECLKKARAKRGPLDLDLPERKIKLDEAGRVERIFT
PARLDAHKLIEEFMILANVCAAETLEAHHQPLIYRTHDEPTIEKLNALAEFLHTIDIKLAKGQVLRPAQFNGILAQVRET
EHEHLVNEIVLRTQAQAEYVTENYGHFGLNLRRYAHFTSPIRRYADLIVHRALISALKFGSDGLPNTDPHVLAEIAAKIS
AAERRAMAAERETVERLIAIHLADQVGAQFEGRISGVTKSGLFIRLMDSGADGFVPISSLAQDYFRHDEARHALIGSRTG
LMHRLGDLVTVRLVEAAPLAGALRFELIDGGALAPRSKGRNGSAKGSAKRSFDPKAEEALAKKNIKRSRRR
>Mature_791_residues
MRKTAVPPSYTASDAETSPGAGRLPSRADLIAFIAREREAQGDKVPAKIGKREIARAFDIKGDDRIALKRMLRELEAEGA
IERRRRVLHQPGRLPAVVLAEIFSRDRDGDLLASPVEWDASLGPIPKIAISAPRKPRANMPAPGLGDRALVRVEAVPDPA
PHEPTYTGRLIKLLPRARTQVLGLFRADPLGGGGRIVPIDKKSLGRGELQVSEADRGEAEDGDLVAVEPLRSGRLGLPSA
RVRERIGAFSSEKAVSLIAIHAHGLPHIFPSEVLAEAESKKNVGLAGREDWRELPLVTIDPPDAKDHDDAVYADYDPDPA
NVGGTILSVAIADVAAYVRLGGALDKEAQERGNSVYFPDRVVPMLPERISNDLCSLRPGEDRPALAVRMVIAADGHKLSH
TFHRVIMRSAAKLSYAQAQAAIDGAPDDVTEPLLETVLRPLYAAHECLKKARAKRGPLDLDLPERKIKLDEAGRVERIFT
PARLDAHKLIEEFMILANVCAAETLEAHHQPLIYRTHDEPTIEKLNALAEFLHTIDIKLAKGQVLRPAQFNGILAQVRET
EHEHLVNEIVLRTQAQAEYVTENYGHFGLNLRRYAHFTSPIRRYADLIVHRALISALKFGSDGLPNTDPHVLAEIAAKIS
AAERRAMAAERETVERLIAIHLADQVGAQFEGRISGVTKSGLFIRLMDSGADGFVPISSLAQDYFRHDEARHALIGSRTG
LMHRLGDLVTVRLVEAAPLAGALRFELIDGGALAPRSKGRNGSAKGSAKRSFDPKAEEALAKKNIKRSRRR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=552, Percent_Identity=28.804347826087, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI190014623, Length=552, Percent_Identity=28.804347826087, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI134288890, Length=485, Percent_Identity=29.2783505154639, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI219521928, Length=595, Percent_Identity=27.8991596638655, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI19115966, Length=595, Percent_Identity=27.8991596638655, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI156105695, Length=142, Percent_Identity=36.6197183098592, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI156105693, Length=142, Percent_Identity=36.6197183098592, Blast_Score=71, Evalue=4e-12,
Organism=Escherichia coli, GI87082383, Length=765, Percent_Identity=34.9019607843137, Blast_Score=347, Evalue=2e-96,
Organism=Escherichia coli, GI1787542, Length=419, Percent_Identity=33.890214797136, Blast_Score=177, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI212645896, Length=478, Percent_Identity=30.1255230125523, Blast_Score=175, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17553506, Length=482, Percent_Identity=28.6307053941909, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324552, Length=433, Percent_Identity=30.715935334873, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24649634, Length=619, Percent_Identity=26.8174474959612, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19922976, Length=379, Percent_Identity=29.023746701847, Blast_Score=136, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24654597, Length=379, Percent_Identity=29.023746701847, Blast_Score=136, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24654592, Length=380, Percent_Identity=28.9473684210526, Blast_Score=136, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 86505; Mature: 86505

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTAVPPSYTASDAETSPGAGRLPSRADLIAFIAREREAQGDKVPAKIGKREIARAFDI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
KGDDRIALKRMLRELEAEGAIERRRRVLHQPGRLPAVVLAEIFSRDRDGDLLASPVEWDA
CCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCC
SLGPIPKIAISAPRKPRANMPAPGLGDRALVRVEAVPDPAPHEPTYTGRLIKLLPRARTQ
CCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
VLGLFRADPLGGGGRIVPIDKKSLGRGELQVSEADRGEAEDGDLVAVEPLRSGRLGLPSA
HHHHHCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCHH
RVRERIGAFSSEKAVSLIAIHAHGLPHIFPSEVLAEAESKKNVGLAGREDWRELPLVTID
HHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEC
PPDAKDHDDAVYADYDPDPANVGGTILSVAIADVAAYVRLGGALDKEAQERGNSVYFPDR
CCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEECCCC
VVPMLPERISNDLCSLRPGEDRPALAVRMVIAADGHKLSHTFHRVIMRSAAKLSYAQAQA
HHHHHHHHHCCHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
AIDGAPDDVTEPLLETVLRPLYAAHECLKKARAKRGPLDLDLPERKIKLDEAGRVERIFT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEECCCCCCCHHHCC
PARLDAHKLIEEFMILANVCAAETLEAHHQPLIYRTHDEPTIEKLNALAEFLHTIDIKLA
CHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEC
KGQVLRPAQFNGILAQVRETEHEHLVNEIVLRTQAQAEYVTENYGHFGLNLRRYAHFTSP
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
IRRYADLIVHRALISALKFGSDGLPNTDPHVLAEIAAKISAAERRAMAAERETVERLIAI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLADQVGAQFEGRISGVTKSGLFIRLMDSGADGFVPISSLAQDYFRHDEARHALIGSRTG
HHHHHHCCCCCCCCCCEECCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHCHHH
LMHRLGDLVTVRLVEAAPLAGALRFELIDGGALAPRSKGRNGSAKGSAKRSFDPKAEEAL
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AKKNIKRSRRR
HHHHHHHHHCC
>Mature Secondary Structure
MRKTAVPPSYTASDAETSPGAGRLPSRADLIAFIAREREAQGDKVPAKIGKREIARAFDI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
KGDDRIALKRMLRELEAEGAIERRRRVLHQPGRLPAVVLAEIFSRDRDGDLLASPVEWDA
CCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCC
SLGPIPKIAISAPRKPRANMPAPGLGDRALVRVEAVPDPAPHEPTYTGRLIKLLPRARTQ
CCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
VLGLFRADPLGGGGRIVPIDKKSLGRGELQVSEADRGEAEDGDLVAVEPLRSGRLGLPSA
HHHHHCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCHH
RVRERIGAFSSEKAVSLIAIHAHGLPHIFPSEVLAEAESKKNVGLAGREDWRELPLVTID
HHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEC
PPDAKDHDDAVYADYDPDPANVGGTILSVAIADVAAYVRLGGALDKEAQERGNSVYFPDR
CCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEECCCC
VVPMLPERISNDLCSLRPGEDRPALAVRMVIAADGHKLSHTFHRVIMRSAAKLSYAQAQA
HHHHHHHHHCCHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
AIDGAPDDVTEPLLETVLRPLYAAHECLKKARAKRGPLDLDLPERKIKLDEAGRVERIFT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEECCCCCCCHHHCC
PARLDAHKLIEEFMILANVCAAETLEAHHQPLIYRTHDEPTIEKLNALAEFLHTIDIKLA
CHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEC
KGQVLRPAQFNGILAQVRETEHEHLVNEIVLRTQAQAEYVTENYGHFGLNLRRYAHFTSP
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
IRRYADLIVHRALISALKFGSDGLPNTDPHVLAEIAAKISAAERRAMAAERETVERLIAI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLADQVGAQFEGRISGVTKSGLFIRLMDSGADGFVPISSLAQDYFRHDEARHALIGSRTG
HHHHHHCCCCCCCCCCEECCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHCHHH
LMHRLGDLVTVRLVEAAPLAGALRFELIDGGALAPRSKGRNGSAKGSAKRSFDPKAEEAL
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AKKNIKRSRRR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]