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The map label for this gene is yajO [H]

Identifier: 182680241

GI number: 182680241

Start: 3795229

End: 3796260

Strand: Reverse

Name: yajO [H]

Synonym: Bind_3340

Alternate gene names: 182680241

Gene position: 3796260-3795229 (Counterclockwise)

Preceding gene: 182680242

Following gene: 182680237

Centisome position: 91.03

GC content: 57.36

Gene sequence:

>1032_bases
ATGGATTATCGGCAGCTTGGCCGCTCCGGCTTGAAGGTTCCTGTCCTCAGTTTTGGAACGGCGACATTCGGCGGATCGAA
TGAATTCTTCAAACGCTGGGGCGATACGGATGTCGCCGAGGCGACGCGGATGATCGATCTCTGTATCGATCATGGCGTCA
ATTTCTTCGATACGGCCGATGTCTATTCAGAAGGGGCTTCCGAAGAGGTTTTGGGACAGGCGATCAAGGGCAAGCGGGAC
AAGGTCCTGATTTCGACCAAGGCCACTTTCGCCACCGGCAGCGGTCCCAATGAAGTCGGTTCATCCCGTTTCCATTTGAT
CCGGGCTTGCGAGGCCAGCCTGAAGCGGCTCGGGACGGATCATATCGATGTCTATTTCATGCATGCTTTCGATGCCCTGA
CGCCGGTCGAAGAGACATTGCATGCGCTCGATCATCTCATCACTAGCGGCAAGGTTGGCTATATTGGCGCATCGAATTTT
TCCGGCTGGCATTTGATGAAATCCCTGGCGGCGTCGGAGCAGCGTGGCTTGGCGCGTTATGTCGCTTATCAGGGCTATTA
TTCGCTGGTCGGTCGCGATTACGAATGGGAATTGATGCCGCTTGGCCTCGATCAGGGTGTCTCCCTGATGGTCTGGAGCC
CACTCGGCTGGGGACGCCTGACGGGCAAGATTCGCCGCGGCGCACCGGTTACCGAAGGCCGCATTGCGACTGGCGGTGCG
GAAGGGGGACCGATCGTCGATCAGGACTATCTCTTTACCGTCGTGGATGCGCTCGATCTCGTTGCCAAGGAGACCGGCAA
GACCGTTGCTCAGGTCGCCTTGAATTGGTTGCTGCAGCGTCCGACCGTAGCCAATATCGTGATCGGCGCACGCAATGAGG
AACAACTCAAACAGAATCTTGGCGCCGTGGGGTGGCAGCTTACGGCCGAGCAGGTCGCGTTGCTCGACAAGGCCAGCCAT
CGTGTGCCGACCTATCCCTATTGGCATCAGATTCAATTCGGCGAGCGCAATCCAAAGCCGACGGATTGGTAG

Upstream 100 bases:

>100_bases
ATGCGGCTCGTCTCGCAAATCGGTTAGTGTGATGCTCACGTCAAGGGTGATGCCAAAGGCCTGATTATTGGCGTCGGCTA
TATAGGAGGAGGAACGGACC

Downstream 100 bases:

>100_bases
TCTTTCTGGTAGCAAAGGCCGCCAGTCTTGTTAGCGAGAGCATACGTTCACTGGTGTGTGCCATGCTCTCGCTTCGTGTA
TAATTGAAGTATGTTATGCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDYRQLGRSGLKVPVLSFGTATFGGSNEFFKRWGDTDVAEATRMIDLCIDHGVNFFDTADVYSEGASEEVLGQAIKGKRD
KVLISTKATFATGSGPNEVGSSRFHLIRACEASLKRLGTDHIDVYFMHAFDALTPVEETLHALDHLITSGKVGYIGASNF
SGWHLMKSLAASEQRGLARYVAYQGYYSLVGRDYEWELMPLGLDQGVSLMVWSPLGWGRLTGKIRRGAPVTEGRIATGGA
EGGPIVDQDYLFTVVDALDLVAKETGKTVAQVALNWLLQRPTVANIVIGARNEEQLKQNLGAVGWQLTAEQVALLDKASH
RVPTYPYWHQIQFGERNPKPTDW

Sequences:

>Translated_343_residues
MDYRQLGRSGLKVPVLSFGTATFGGSNEFFKRWGDTDVAEATRMIDLCIDHGVNFFDTADVYSEGASEEVLGQAIKGKRD
KVLISTKATFATGSGPNEVGSSRFHLIRACEASLKRLGTDHIDVYFMHAFDALTPVEETLHALDHLITSGKVGYIGASNF
SGWHLMKSLAASEQRGLARYVAYQGYYSLVGRDYEWELMPLGLDQGVSLMVWSPLGWGRLTGKIRRGAPVTEGRIATGGA
EGGPIVDQDYLFTVVDALDLVAKETGKTVAQVALNWLLQRPTVANIVIGARNEEQLKQNLGAVGWQLTAEQVALLDKASH
RVPTYPYWHQIQFGERNPKPTDW
>Mature_343_residues
MDYRQLGRSGLKVPVLSFGTATFGGSNEFFKRWGDTDVAEATRMIDLCIDHGVNFFDTADVYSEGASEEVLGQAIKGKRD
KVLISTKATFATGSGPNEVGSSRFHLIRACEASLKRLGTDHIDVYFMHAFDALTPVEETLHALDHLITSGKVGYIGASNF
SGWHLMKSLAASEQRGLARYVAYQGYYSLVGRDYEWELMPLGLDQGVSLMVWSPLGWGRLTGKIRRGAPVTEGRIATGGA
EGGPIVDQDYLFTVVDALDLVAKETGKTVAQVALNWLLQRPTVANIVIGARNEEQLKQNLGAVGWQLTAEQVALLDKASH
RVPTYPYWHQIQFGERNPKPTDW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=311, Percent_Identity=35.6913183279743, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=35.5987055016181, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI27436964, Length=311, Percent_Identity=35.048231511254, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI27436962, Length=310, Percent_Identity=34.8387096774194, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI27436966, Length=311, Percent_Identity=34.7266881028939, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI27436971, Length=329, Percent_Identity=33.7386018237082, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI223718702, Length=304, Percent_Identity=29.9342105263158, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI41152114, Length=303, Percent_Identity=30.03300330033, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI41327764, Length=276, Percent_Identity=30.0724637681159, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI223718708, Length=169, Percent_Identity=33.7278106508876, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=37.8125, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=31.0975609756098, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789199, Length=359, Percent_Identity=30.08356545961, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788070, Length=341, Percent_Identity=30.2052785923754, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788081, Length=271, Percent_Identity=29.8892988929889, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI48994888, Length=292, Percent_Identity=27.0547945205479, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI212645785, Length=315, Percent_Identity=25.0793650793651, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=27.2189349112426, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=28.6604361370716, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319958, Length=298, Percent_Identity=28.8590604026846, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322615, Length=249, Percent_Identity=28.9156626506024, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=320, Percent_Identity=25.625, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24640980, Length=348, Percent_Identity=25.5747126436782, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45549126, Length=348, Percent_Identity=25.5747126436782, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=26.1261261261261, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646159, Length=339, Percent_Identity=26.2536873156342, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644950, Length=360, Percent_Identity=27.2222222222222, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37726; Mature: 37726

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRQLGRSGLKVPVLSFGTATFGGSNEFFKRWGDTDVAEATRMIDLCIDHGVNFFDTAD
CCHHHHCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEECHH
VYSEGASEEVLGQAIKGKRDKVLISTKATFATGSGPNEVGSSRFHLIRACEASLKRLGTD
HHHCCCCHHHHHHHHCCCCCEEEEEECCEEECCCCCHHHCCHHHHHHHHHHHHHHHCCCC
HIDVYFMHAFDALTPVEETLHALDHLITSGKVGYIGASNFSGWHLMKSLAASEQRGLARY
CCEEEEEHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VAYQGYYSLVGRDYEWELMPLGLDQGVSLMVWSPLGWGRLTGKIRRGAPVTEGRIATGGA
HHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCHHHCCHHHCCCCCCCCEEEECCC
EGGPIVDQDYLFTVVDALDLVAKETGKTVAQVALNWLLQRPTVANIVIGARNEEQLKQNL
CCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
GAVGWQLTAEQVALLDKASHRVPTYPYWHQIQFGERNPKPTDW
CCCCEEHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MDYRQLGRSGLKVPVLSFGTATFGGSNEFFKRWGDTDVAEATRMIDLCIDHGVNFFDTAD
CCHHHHCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEECHH
VYSEGASEEVLGQAIKGKRDKVLISTKATFATGSGPNEVGSSRFHLIRACEASLKRLGTD
HHHCCCCHHHHHHHHCCCCCEEEEEECCEEECCCCCHHHCCHHHHHHHHHHHHHHHCCCC
HIDVYFMHAFDALTPVEETLHALDHLITSGKVGYIGASNFSGWHLMKSLAASEQRGLARY
CCEEEEEHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VAYQGYYSLVGRDYEWELMPLGLDQGVSLMVWSPLGWGRLTGKIRRGAPVTEGRIATGGA
HHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCHHHCCHHHCCCCCCCCEEEECCC
EGGPIVDQDYLFTVVDALDLVAKETGKTVAQVALNWLLQRPTVANIVIGARNEEQLKQNL
CCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
GAVGWQLTAEQVALLDKASHRVPTYPYWHQIQFGERNPKPTDW
CCCCEEHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]