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The map label for this gene is grx [H]

Identifier: 182680212

GI number: 182680212

Start: 3766697

End: 3766984

Strand: Reverse

Name: grx [H]

Synonym: Bind_3310

Alternate gene names: 182680212

Gene position: 3766984-3766697 (Counterclockwise)

Preceding gene: 182680219

Following gene: 182680211

Centisome position: 90.33

GC content: 54.51

Gene sequence:

>288_bases
ATGTCCGAACTGCCTGAAATCACCATCTATACGACGCAGACCTGCCCCTATTGCCGGAGGGCCAAGGAGCTCCTCACGAA
GAAGAATCTGCCGTTCACGGAAATTTCAGTCGATGGCGACTTTGAAGCCCGGGAACGCATGACCGAGCGGGCCAATGGAC
GCAGCACCGTGCCGCAGATTTTCTTTGGCGATAAGCATATTGGCGGCTGCGACGATCTTTATGAACTGCATTATGATGGC
AAGCTTGATCTGCTTCTGGCCGATCTCGCCCGTACGCCTACCGATTGA

Upstream 100 bases:

>100_bases
TTGCTTGCCGGAGCCTTGCGGGCACCCGCCACGGGCGCGGCCACCGGCTTGTCGACGGTGGCCCTTTGCTTCATAAAGGT
CGCGAGAAAAGGAATTTCGA

Downstream 100 bases:

>100_bases
GAAATATGATCAAATTCGCTTTGATCTGCGACCAGAAACATCGGTTTGAAAGCTGGTTCCAAAGCGGTGCCGCTTTCGAC
CGCCAGGTCGAGGATGGTTT

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 95; Mature: 94

Protein sequence:

>95_residues
MSELPEITIYTTQTCPYCRRAKELLTKKNLPFTEISVDGDFEARERMTERANGRSTVPQIFFGDKHIGGCDDLYELHYDG
KLDLLLADLARTPTD

Sequences:

>Translated_95_residues
MSELPEITIYTTQTCPYCRRAKELLTKKNLPFTEISVDGDFEARERMTERANGRSTVPQIFFGDKHIGGCDDLYELHYDG
KLDLLLADLARTPTD
>Mature_94_residues
SELPEITIYTTQTCPYCRRAKELLTKKNLPFTEISVDGDFEARERMTERANGRSTVPQIFFGDKHIGGCDDLYELHYDGK
LDLLLADLARTPTD

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=54.2168674698795, Blast_Score=96, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 10857; Mature: 10726

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELPEITIYTTQTCPYCRRAKELLTKKNLPFTEISVDGDFEARERMTERANGRSTVPQI
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCEE
FFGDKHIGGCDDLYELHYDGKLDLLLADLARTPTD
EECCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SELPEITIYTTQTCPYCRRAKELLTKKNLPFTEISVDGDFEARERMTERANGRSTVPQI
CCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCEE
FFGDKHIGGCDDLYELHYDGKLDLLLADLARTPTD
EECCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]