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The map label for this gene is gpsA

Identifier: 182680122

GI number: 182680122

Start: 3662720

End: 3663727

Strand: Reverse

Name: gpsA

Synonym: Bind_3219

Alternate gene names: 182680122

Gene position: 3663727-3662720 (Counterclockwise)

Preceding gene: 182680123

Following gene: 182680121

Centisome position: 87.86

GC content: 64.68

Gene sequence:

>1008_bases
ATGGCGCGCTGGCGGCGGATCGTGGCTCTTGGCGGCGGCGCCTGGGGGACCGCGCTCGCCAATCTCGCCGCGCGCGCCGG
GGCCGAGGATGTGGCGCTCTGGACGCGGGACGCAGCCCATGTCGCGGAAATGACCGCGACCGGCGTCAATGCCCGTAGAT
TGCCCGGCATTCCACTTCATTCAGCCCTGCGTCCGACGACCGATCTCGGTGTCGTGGCCGAGGCTGATCTGATCCTCGCC
GTGGTGCCTTCCCAAAGCCTGCGCGGTGTGTTGGAGCAGATCCAATCGACCTTGCCGACGCCGACGCCTCTCATTCTTTG
CTGCAAGGGCATCGAACATGAGACGGGCCTGTTCATGAGCGAGGTCGCTGCTGATGTCCTTGGCGATCAGCCGGTCGCTG
TTCTGTCCGGGCCAAGCTTCGCCGAGGATGTGGCGCGCGGCAAGCCGACAGCGGTTACCCTCGCCGCTTATGATGGCGCG
TTGGCGGCGGCGCTGGTCGAGGCTTTGGCCGCGCCCTGGTTCCGACTTTATCACACGCATGACGTGCGAGGCGTCGAGAT
TGGCGGCGCGGCCAAAAATGTTCTGGCGATTGCCAATGGCATTGCCGCCGGACGCGATCTCGGGGCCAGCGCCGGGGCGG
CGCTGATCGCACGGGGCTTTGCCGAACTCTGTCGTTTCGGCCGCGCCTTTGGTGTGGAGATGGGGACGCTCGCGGGCCTT
TCCGGTCTCGGCGATCTCGTCCTGACCTGCGGCTCGGCGCAATCGCGCAATTATTCTTTCGGCCATGCGCTTGGACGCGG
CACCTCGATCAATGATGCGCGTGCCAACATTGGCCTTGTCGAGGGTTTTTTCACCTGCGGTATTCTCAATGATCTCGCCC
GGGCGAAAGGTGTCGATATGCCGATCGCCCAGGCGGTCGAGGCGGTTCTTGCCGAAAGAATGGGTGTCGACGAAGCGATT
GCCACCTTGCTGGCGCGTCCATCCAAGGCGGAACTGGCGGGTTTTTGA

Upstream 100 bases:

>100_bases
ATGTGGGGCGTTGCATGGCTGGGCTTGGCGGATTATGCCGAACAAGTCTTGGGAAAAGCCCTGAGTATTCTTATCGACCG
TTTGTGGGGAAGGACGAAGG

Downstream 100 bases:

>100_bases
GGAACGCGGCGCGGTTTAGGAGCTAGGCACGGATGGCACATTGGCTGATCAAGAGCGAGCCGAACAAATGGTCCTGGGAT
GACCAGGTCAAGGCCGCGCG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MARWRRIVALGGGAWGTALANLAARAGAEDVALWTRDAAHVAEMTATGVNARRLPGIPLHSALRPTTDLGVVAEADLILA
VVPSQSLRGVLEQIQSTLPTPTPLILCCKGIEHETGLFMSEVAADVLGDQPVAVLSGPSFAEDVARGKPTAVTLAAYDGA
LAAALVEALAAPWFRLYHTHDVRGVEIGGAAKNVLAIANGIAAGRDLGASAGAALIARGFAELCRFGRAFGVEMGTLAGL
SGLGDLVLTCGSAQSRNYSFGHALGRGTSINDARANIGLVEGFFTCGILNDLARAKGVDMPIAQAVEAVLAERMGVDEAI
ATLLARPSKAELAGF

Sequences:

>Translated_335_residues
MARWRRIVALGGGAWGTALANLAARAGAEDVALWTRDAAHVAEMTATGVNARRLPGIPLHSALRPTTDLGVVAEADLILA
VVPSQSLRGVLEQIQSTLPTPTPLILCCKGIEHETGLFMSEVAADVLGDQPVAVLSGPSFAEDVARGKPTAVTLAAYDGA
LAAALVEALAAPWFRLYHTHDVRGVEIGGAAKNVLAIANGIAAGRDLGASAGAALIARGFAELCRFGRAFGVEMGTLAGL
SGLGDLVLTCGSAQSRNYSFGHALGRGTSINDARANIGLVEGFFTCGILNDLARAKGVDMPIAQAVEAVLAERMGVDEAI
ATLLARPSKAELAGF
>Mature_334_residues
ARWRRIVALGGGAWGTALANLAARAGAEDVALWTRDAAHVAEMTATGVNARRLPGIPLHSALRPTTDLGVVAEADLILAV
VPSQSLRGVLEQIQSTLPTPTPLILCCKGIEHETGLFMSEVAADVLGDQPVAVLSGPSFAEDVARGKPTAVTLAAYDGAL
AAALVEALAAPWFRLYHTHDVRGVEIGGAAKNVLAIANGIAAGRDLGASAGAALIARGFAELCRFGRAFGVEMGTLAGLS
GLGDLVLTCGSAQSRNYSFGHALGRGTSINDARANIGLVEGFFTCGILNDLARAKGVDMPIAQAVEAVLAERMGVDEAIA
TLLARPSKAELAGF

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=347, Percent_Identity=30.5475504322767, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI24307999, Length=352, Percent_Identity=26.4204545454545, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1790037, Length=329, Percent_Identity=42.8571428571429, Blast_Score=228, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI32564399, Length=274, Percent_Identity=28.4671532846715, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193210136, Length=283, Percent_Identity=27.9151943462898, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32564403, Length=283, Percent_Identity=27.9151943462898, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17507425, Length=277, Percent_Identity=28.8808664259928, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324513, Length=274, Percent_Identity=28.4671532846715, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320181, Length=343, Percent_Identity=27.4052478134111, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI22026922, Length=269, Percent_Identity=24.5353159851301, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17136202, Length=353, Percent_Identity=26.0623229461756, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17136204, Length=350, Percent_Identity=26.2857142857143, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17136200, Length=353, Percent_Identity=26.0623229461756, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362270, Length=294, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45551945, Length=294, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648969, Length=249, Percent_Identity=26.9076305220884, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_BEII9 (B2ID14)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001834268.1
- ProteinModelPortal:   B2ID14
- GeneID:   6198981
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_3219
- HOGENOM:   HBG586392
- OMA:   AKGIEHG
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34336; Mature: 34205

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 192-192 BINDING 109-109 BINDING 109-109 BINDING 141-141 BINDING 256-256 BINDING 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARWRRIVALGGGAWGTALANLAARAGAEDVALWTRDAAHVAEMTATGVNARRLPGIPLH
CCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
SALRPTTDLGVVAEADLILAVVPSQSLRGVLEQIQSTLPTPTPLILCCKGIEHETGLFMS
HHCCCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH
EVAADVLGDQPVAVLSGPSFAEDVARGKPTAVTLAAYDGALAAALVEALAAPWFRLYHTH
HHHHHHHCCCCEEEECCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCC
DVRGVEIGGAAKNVLAIANGIAAGRDLGASAGAALIARGFAELCRFGRAFGVEMGTLAGL
CCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SGLGDLVLTCGSAQSRNYSFGHALGRGTSINDARANIGLVEGFFTCGILNDLARAKGVDM
HHHHHHHEECCCCCCCCCCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCC
PIAQAVEAVLAERMGVDEAIATLLARPSKAELAGF
CHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure 
ARWRRIVALGGGAWGTALANLAARAGAEDVALWTRDAAHVAEMTATGVNARRLPGIPLH
CCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
SALRPTTDLGVVAEADLILAVVPSQSLRGVLEQIQSTLPTPTPLILCCKGIEHETGLFMS
HHCCCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH
EVAADVLGDQPVAVLSGPSFAEDVARGKPTAVTLAAYDGALAAALVEALAAPWFRLYHTH
HHHHHHHCCCCEEEECCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCC
DVRGVEIGGAAKNVLAIANGIAAGRDLGASAGAALIARGFAELCRFGRAFGVEMGTLAGL
CCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SGLGDLVLTCGSAQSRNYSFGHALGRGTSINDARANIGLVEGFFTCGILNDLARAKGVDM
HHHHHHHEECCCCCCCCCCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCC
PIAQAVEAVLAERMGVDEAIATLLARPSKAELAGF
CHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA