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The map label for this gene is ppdK [H]

Identifier: 182679999

GI number: 182679999

Start: 3539168

End: 3540763

Strand: Reverse

Name: ppdK [H]

Synonym: Bind_3095

Alternate gene names: 182679999

Gene position: 3540763-3539168 (Counterclockwise)

Preceding gene: 182680000

Following gene: 182679998

Centisome position: 84.91

GC content: 61.72

Gene sequence:

>1596_bases
ATGCAGATCGTGCGTATCGCGACCGGAACGAACGAGGCACATTCCGCAGATCTCATCGGAGCGAAGGCTGCCAATCTGGA
GCGCATGGCTGCGCTCGGCCTTCCCGTTCCGCCGGCCTTCGTCCTGCCGATCACGCTTTGTTCCGCGATCCTGCGCAGTG
AGCCCGAGGCGGAAAAGGCCTTGGTCAAGGGTCTCGAAGAAGGGATCGCTTATCTCGAAGAGGCCACCGGCAGACGGTTT
GGTGATCACCGCCATCCGCTGCTCATTTCCGTGCGTTCGGGAGCGGCGCGGTCCATGCCCGGCATGTTGGAAACCGTGCT
CGATGTTGGCTGCACGCCTTCTGTTGTGTTGGGCCTCGTGCGTCAGACCGGTCATCCGCGTTTTGCCTGGGATTGTCGCT
GCCGGTTTCTCGACAGCTATGCCGATGTCGTCCTTGGCCTTGATCAGGCGCTTTTGCGCAAACGACGCGATCAGATCATG
GCCGAAGAAGGGGTCCTTGATGCGGGTGATCTCGACAGTGAGGCGCTGGAACGGCTTGCCGGGGCCTATCTGCAGGTGAT
CGAGAGCAACGGCGGATTCATACCGGAAGAGCCGATGCGCCAGGTCGAGGCGGCCGCGCGCATGGTCTTTGGCTCGTGGG
AAAGTGACAAAGCCAAAACCTATCGCAAACTGGAACATCTCGAGGCGCTTGGCGGCACGGCTGTTACGGTCCAGGCCATG
GTGTTCGGCAATGTTGGGCTGACATCGGGGGCCGGTGTCGCCTTTTCGCGTGATCCATCGACGGGCGCGGCGACGCCGGT
AATCGATGTCCTGTTTGAATCGCAAGGCGAGGATGTCGTCTCTGGCCGCCGCACGCCGGAACCGGAAGCGGCTTTGGCGC
GTACCGTGCCCGCCGCCGCCAAGGAATTGGTGGCGACGCTCGCACGGCTTGAACAGGCCTTCGGTGATGTGCAGGATGTC
GAATTCACGATTGAAAACGGCAAATTGTGGTTTCTGCAAACCCGCAGTGCGAAACGCACACCGGCGGCGGCTTTGCGTTT
CGCCGTGGCCTTCGTCAAGGAGGGGCTCATTACGCCCAAGGAGGCGTTGCAGCGGCTGGAAAATATCGATTTCACGCGGG
ATATCGAACATCTCGCCAATCAAAGACTGAGCGCGGTTGGCGAGCCTGTGGGGCATGGAACCGGCGCTTCCACGGGCGTC
GCGATCGGTCGCGCGGCTTTCGATTCCACGAGCGCTCAACGCTTGGCAAAAGCGGGAGATCCCGTCATTCTCCTGCGGCC
GGAAATCAGCACCGCTGACGTCGCGGGTTTTGCCGCCTCGGCGGGAATTGTGACCGCAGTTGGCGGCCGCACCGCCCATG
CGGCACTCGTAGCGCGGCAATTAGGCAAACCCTGTCTGGTCGGCTGCGCCGGCCTTAATGTCGATGTTGCCGGACATACA
GCCCGTTTGCACGACCTGCCGATCAAAGAAGGCGATTGGCTCTCCATCGATGGCGGGGCGGGGACGATTTTCTCGGGACG
CGGCAAGCTTCTCATCGATCGTCCGGAAGCGGAGCTGTCGGAGATTGCGCGCTGGAAAGAAAGCGTGCCAGCGTAA

Upstream 100 bases:

>100_bases
GCGACCGATCGGCTGGCTGGCGCGGGTGGCCTGCTGCGTGACCACGTGCTGGCCGATCTCTCGAAATAATTTTTTCAAAC
TCCATCATCGGAACTTCTTC

Downstream 100 bases:

>100_bases
GCGCTTACAGTTCGCCCACGCATCTAATTGAATGTCCGATCGTGCAGAGCCTCAACCAAAAGGGGAGGGTACTTTTGGTT
GAGCTGGCTTAAAAAGTGCC

Product: pyruvate phosphate dikinase PEP/pyruvate-binding

Products: NA

Alternate protein names: Pyruvate, orthophosphate dikinase [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MQIVRIATGTNEAHSADLIGAKAANLERMAALGLPVPPAFVLPITLCSAILRSEPEAEKALVKGLEEGIAYLEEATGRRF
GDHRHPLLISVRSGAARSMPGMLETVLDVGCTPSVVLGLVRQTGHPRFAWDCRCRFLDSYADVVLGLDQALLRKRRDQIM
AEEGVLDAGDLDSEALERLAGAYLQVIESNGGFIPEEPMRQVEAAARMVFGSWESDKAKTYRKLEHLEALGGTAVTVQAM
VFGNVGLTSGAGVAFSRDPSTGAATPVIDVLFESQGEDVVSGRRTPEPEAALARTVPAAAKELVATLARLEQAFGDVQDV
EFTIENGKLWFLQTRSAKRTPAAALRFAVAFVKEGLITPKEALQRLENIDFTRDIEHLANQRLSAVGEPVGHGTGASTGV
AIGRAAFDSTSAQRLAKAGDPVILLRPEISTADVAGFAASAGIVTAVGGRTAHAALVARQLGKPCLVGCAGLNVDVAGHT
ARLHDLPIKEGDWLSIDGGAGTIFSGRGKLLIDRPEAELSEIARWKESVPA

Sequences:

>Translated_531_residues
MQIVRIATGTNEAHSADLIGAKAANLERMAALGLPVPPAFVLPITLCSAILRSEPEAEKALVKGLEEGIAYLEEATGRRF
GDHRHPLLISVRSGAARSMPGMLETVLDVGCTPSVVLGLVRQTGHPRFAWDCRCRFLDSYADVVLGLDQALLRKRRDQIM
AEEGVLDAGDLDSEALERLAGAYLQVIESNGGFIPEEPMRQVEAAARMVFGSWESDKAKTYRKLEHLEALGGTAVTVQAM
VFGNVGLTSGAGVAFSRDPSTGAATPVIDVLFESQGEDVVSGRRTPEPEAALARTVPAAAKELVATLARLEQAFGDVQDV
EFTIENGKLWFLQTRSAKRTPAAALRFAVAFVKEGLITPKEALQRLENIDFTRDIEHLANQRLSAVGEPVGHGTGASTGV
AIGRAAFDSTSAQRLAKAGDPVILLRPEISTADVAGFAASAGIVTAVGGRTAHAALVARQLGKPCLVGCAGLNVDVAGHT
ARLHDLPIKEGDWLSIDGGAGTIFSGRGKLLIDRPEAELSEIARWKESVPA
>Mature_531_residues
MQIVRIATGTNEAHSADLIGAKAANLERMAALGLPVPPAFVLPITLCSAILRSEPEAEKALVKGLEEGIAYLEEATGRRF
GDHRHPLLISVRSGAARSMPGMLETVLDVGCTPSVVLGLVRQTGHPRFAWDCRCRFLDSYADVVLGLDQALLRKRRDQIM
AEEGVLDAGDLDSEALERLAGAYLQVIESNGGFIPEEPMRQVEAAARMVFGSWESDKAKTYRKLEHLEALGGTAVTVQAM
VFGNVGLTSGAGVAFSRDPSTGAATPVIDVLFESQGEDVVSGRRTPEPEAALARTVPAAAKELVATLARLEQAFGDVQDV
EFTIENGKLWFLQTRSAKRTPAAALRFAVAFVKEGLITPKEALQRLENIDFTRDIEHLANQRLSAVGEPVGHGTGASTGV
AIGRAAFDSTSAQRLAKAGDPVILLRPEISTADVAGFAASAGIVTAVGGRTAHAALVARQLGKPCLVGCAGLNVDVAGHT
ARLHDLPIKEGDWLSIDGGAGTIFSGRGKLLIDRPEAELSEIARWKESVPA

Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR010121
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.1 [H]

Molecular weight: Translated: 56222; Mature: 56222

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIVRIATGTNEAHSADLIGAKAANLERMAALGLPVPPAFVLPITLCSAILRSEPEAEKA
CEEEEEECCCCCCCCCHHHCCHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
LVKGLEEGIAYLEEATGRRFGDHRHPLLISVRSGAARSMPGMLETVLDVGCTPSVVLGLV
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHH
RQTGHPRFAWDCRCRFLDSYADVVLGLDQALLRKRRDQIMAEEGVLDAGDLDSEALERLA
HHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
GAYLQVIESNGGFIPEEPMRQVEAAARMVFGSWESDKAKTYRKLEHLEALGGTAVTVQAM
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEE
VFGNVGLTSGAGVAFSRDPSTGAATPVIDVLFESQGEDVVSGRRTPEPEAALARTVPAAA
EECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHH
KELVATLARLEQAFGDVQDVEFTIENGKLWFLQTRSAKRTPAAALRFAVAFVKEGLITPK
HHHHHHHHHHHHHHCCCEEEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHH
EALQRLENIDFTRDIEHLANQRLSAVGEPVGHGTGASTGVAIGRAAFDSTSAQRLAKAGD
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCC
PVILLRPEISTADVAGFAASAGIVTAVGGRTAHAALVARQLGKPCLVGCAGLNVDVAGHT
CEEEECCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCEEEECCCC
ARLHDLPIKEGDWLSIDGGAGTIFSGRGKLLIDRPEAELSEIARWKESVPA
EEEECCCCCCCCEEEECCCCCEEECCCCCEEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQIVRIATGTNEAHSADLIGAKAANLERMAALGLPVPPAFVLPITLCSAILRSEPEAEKA
CEEEEEECCCCCCCCCHHHCCHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
LVKGLEEGIAYLEEATGRRFGDHRHPLLISVRSGAARSMPGMLETVLDVGCTPSVVLGLV
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHH
RQTGHPRFAWDCRCRFLDSYADVVLGLDQALLRKRRDQIMAEEGVLDAGDLDSEALERLA
HHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
GAYLQVIESNGGFIPEEPMRQVEAAARMVFGSWESDKAKTYRKLEHLEALGGTAVTVQAM
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEE
VFGNVGLTSGAGVAFSRDPSTGAATPVIDVLFESQGEDVVSGRRTPEPEAALARTVPAAA
EECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHH
KELVATLARLEQAFGDVQDVEFTIENGKLWFLQTRSAKRTPAAALRFAVAFVKEGLITPK
HHHHHHHHHHHHHHCCCEEEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHH
EALQRLENIDFTRDIEHLANQRLSAVGEPVGHGTGASTGVAIGRAAFDSTSAQRLAKAGD
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCC
PVILLRPEISTADVAGFAASAGIVTAVGGRTAHAALVARQLGKPCLVGCAGLNVDVAGHT
CEEEECCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCEEEECCCC
ARLHDLPIKEGDWLSIDGGAGTIFSGRGKLLIDRPEAELSEIARWKESVPA
EEEECCCCCCCCEEEECCCCCEEECCCCCEEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2176881; 6257292; 11695893; 11468288; 8610096; 9753432 [H]