Click here to switch to the map view.

The map label for this gene is ltaE [H]

Identifier: 182679934

GI number: 182679934

Start: 3447401

End: 3448474

Strand: Reverse

Name: ltaE [H]

Synonym: Bind_3029

Alternate gene names: 182679934

Gene position: 3448474-3447401 (Counterclockwise)

Preceding gene: 182679935

Following gene: 182679933

Centisome position: 82.69

GC content: 62.76

Gene sequence:

>1074_bases
ATGGAATTTTCAAGCGATAATACGGCCGGGGCGAGCCAGCCCATTCTCGAGGCGATCATCGCGGCCAATGATGGTCATGC
CGCCCCCTATGGAGCGGACACTCTAAGCCTTGAGGCCGAACGCCGTCTTGCCGTGGTTTTCGAGCATGAGCTTGCCTGTT
TTCTGGTGCCGACCGGCACGGCCGCCAATGCTTTGGCGCTCGGCGCGCTCTGTCCGCCCTGGGGCGCTGTCTTCTGCCAC
GAGGACGCCCATGTGATTGCCGATGAATGCGGCGCGCCGGAAATGTTCACAGCCGGTGGCAAGCTTGTCGGCATCGAGGG
CGTGCGTGCCAAGATCACACCGGAAGCCTTCACCGCCAAGCTCGCCGCTTTCCCGCGGGGGCCAGTCAGGCAGGTGCAGC
CGGCGGCCTTGTCCCTGTCGCAAGTGACCGAAGCCGGCACGCTTTACCGACCAGCGGAAATCTCTGCCTTGAGCGAAATC
GCTCATGCGGCGGGGCTTGCCGTGCATATGGATGGAGCCCGTTTCGCCAATGCGCTCGTCGCGCTTGGCTGCACGCCCGC
CGAAATGACCTGGAAGGCGGGCATTGATGTGCTCTCCTTCGGCGCCACCAAGAATGGCGCTTGGGCCTGCGAGGCGGTCT
TGTTCTTCGATCCCGAAAAAGCGCGCGACTTCATCTATCGCCGCAAGCGCGGTGGTCATACCGTCTCCAAAAGCCGGCTG
CTGGGTGCGCAGATGACGGCTTATCTCGACCAGGATCATTGGCTGGACCTGGCGAGAATCGCCAATGCCCGTGCGCGCCG
GCTTGCTGAAGGGATCGCGCGCATTCCGGGACTGCGGCTCGCCTGGCCCTGCGAGGCCAATGAGGTTTTCGTGGTTCTTT
CCGAAGAGGTTGACAAGGTTTTGCAGAAGGCCGGGGGACATTATTATACTTGGGATAAGCCGGGCCTGATGGAGGGGCCG
CCGGTCGGTCCCACGGAAGTCCTCGCGCGTCTCGTGACCTCCTTTGCGACCAAGGATGAGGCGATCGACCAATTCCTGGC
TGTCGCGGCGGCGGCAGCACAGAAACATGCCTGA

Upstream 100 bases:

>100_bases
TGGCTTGGCTTTCTCTGTTTCCGCTTTTCGATCTTGGTCGTGACGGGCGACCTGATATAACCGAAAAGGGGCGGATCGGA
TCATAAAGCGGCGCGGTGCA

Downstream 100 bases:

>100_bases
GCAACCCTGCCAAGGAAAGGCGAGGCGATGACGAAAGCCATTCTGGTGCATGAAGTGGGTGGGCCCGAGGTCATGCACCT
TGAGGAGATCACTTTGCCGC

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MEFSSDNTAGASQPILEAIIAANDGHAAPYGADTLSLEAERRLAVVFEHELACFLVPTGTAANALALGALCPPWGAVFCH
EDAHVIADECGAPEMFTAGGKLVGIEGVRAKITPEAFTAKLAAFPRGPVRQVQPAALSLSQVTEAGTLYRPAEISALSEI
AHAAGLAVHMDGARFANALVALGCTPAEMTWKAGIDVLSFGATKNGAWACEAVLFFDPEKARDFIYRRKRGGHTVSKSRL
LGAQMTAYLDQDHWLDLARIANARARRLAEGIARIPGLRLAWPCEANEVFVVLSEEVDKVLQKAGGHYYTWDKPGLMEGP
PVGPTEVLARLVTSFATKDEAIDQFLAVAAAAAQKHA

Sequences:

>Translated_357_residues
MEFSSDNTAGASQPILEAIIAANDGHAAPYGADTLSLEAERRLAVVFEHELACFLVPTGTAANALALGALCPPWGAVFCH
EDAHVIADECGAPEMFTAGGKLVGIEGVRAKITPEAFTAKLAAFPRGPVRQVQPAALSLSQVTEAGTLYRPAEISALSEI
AHAAGLAVHMDGARFANALVALGCTPAEMTWKAGIDVLSFGATKNGAWACEAVLFFDPEKARDFIYRRKRGGHTVSKSRL
LGAQMTAYLDQDHWLDLARIANARARRLAEGIARIPGLRLAWPCEANEVFVVLSEEVDKVLQKAGGHYYTWDKPGLMEGP
PVGPTEVLARLVTSFATKDEAIDQFLAVAAAAAQKHA
>Mature_357_residues
MEFSSDNTAGASQPILEAIIAANDGHAAPYGADTLSLEAERRLAVVFEHELACFLVPTGTAANALALGALCPPWGAVFCH
EDAHVIADECGAPEMFTAGGKLVGIEGVRAKITPEAFTAKLAAFPRGPVRQVQPAALSLSQVTEAGTLYRPAEISALSEI
AHAAGLAVHMDGARFANALVALGCTPAEMTWKAGIDVLSFGATKNGAWACEAVLFFDPEKARDFIYRRKRGGHTVSKSRL
LGAQMTAYLDQDHWLDLARIANARARRLAEGIARIPGLRLAWPCEANEVFVVLSEEVDKVLQKAGGHYYTWDKPGLMEGP
PVGPTEVLARLVTSFATKDEAIDQFLAVAAAAAQKHA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37883; Mature: 37883

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFSSDNTAGASQPILEAIIAANDGHAAPYGADTLSLEAERRLAVVFEHELACFLVPTGT
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEEECCEEEEEEECCC
AANALALGALCPPWGAVFCHEDAHVIADECGAPEMFTAGGKLVGIEGVRAKITPEAFTAK
CHHHHHHCCCCCCCCEEEECCCCHHHHHHCCCCCEEECCCCEEEECCCEEEECHHHHHHH
LAAFPRGPVRQVQPAALSLSQVTEAGTLYRPAEISALSEIAHAAGLAVHMDGARFANALV
HHHCCCCCCHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHH
ALGCTPAEMTWKAGIDVLSFGATKNGAWACEAVLFFDPEKARDFIYRRKRGGHTVSKSRL
HCCCCCHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCHHHHHHHHHHHCCCCCCHHHHH
LGAQMTAYLDQDHWLDLARIANARARRLAEGIARIPGLRLAWPCEANEVFVVLSEEVDKV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEHHHHHHH
LQKAGGHYYTWDKPGLMEGPPVGPTEVLARLVTSFATKDEAIDQFLAVAAAAAQKHA
HHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEFSSDNTAGASQPILEAIIAANDGHAAPYGADTLSLEAERRLAVVFEHELACFLVPTGT
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEEECCEEEEEEECCC
AANALALGALCPPWGAVFCHEDAHVIADECGAPEMFTAGGKLVGIEGVRAKITPEAFTAK
CHHHHHHCCCCCCCCEEEECCCCHHHHHHCCCCCEEECCCCEEEECCCEEEECHHHHHHH
LAAFPRGPVRQVQPAALSLSQVTEAGTLYRPAEISALSEIAHAAGLAVHMDGARFANALV
HHHCCCCCCHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHH
ALGCTPAEMTWKAGIDVLSFGATKNGAWACEAVLFFDPEKARDFIYRRKRGGHTVSKSRL
HCCCCCHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCHHHHHHHHHHHCCCCCCHHHHH
LGAQMTAYLDQDHWLDLARIANARARRLAEGIARIPGLRLAWPCEANEVFVVLSEEVDKV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEHHHHHHH
LQKAGGHYYTWDKPGLMEGPPVGPTEVLARLVTSFATKDEAIDQFLAVAAAAAQKHA
HHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]