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The map label for this gene is tqsA [H]

Identifier: 182679902

GI number: 182679902

Start: 3403150

End: 3404283

Strand: Reverse

Name: tqsA [H]

Synonym: Bind_2995

Alternate gene names: 182679902

Gene position: 3404283-3403150 (Counterclockwise)

Preceding gene: 182679913

Following gene: 182679900

Centisome position: 81.63

GC content: 51.06

Gene sequence:

>1134_bases
ATGACATCTTCCAGGGAGGGAGTAACACCCAATGCGCAAGCGGGTGCCAAAGAATTGCCGGATACGGCAGACCAAAATAT
ATTGCCCGCACAGGATCCAAATACGGTCTTGTTGGCAGGTCTTTTTCTGATTGCTGCTCTAAGCGGCGCGTATGTTGCCG
CCGAGGTCGTCCTCCCCCTCATTTTTGCGATCGTCTTGAAATTACTTCTGCAACCTGGCATGAGATTTTTAGAGCGATAC
TATATTCCTCGGCATCTGGCTGCATTCTTTCTTATCCTTGCGGTGCTTGGCGCAATTCTGGGCATTGGAGCTGCTGTGTC
GGGCCCGTCGAAGGCTTGGTTCGAGCATCTTTCTGAAGGACTCCCGCTCTTGCGGGAAAGGTTACTTTTTCTCAGCCATC
CGTTTGAATTACTCGACACGTTGCGGAACAAGATGGATGGCATGGGGCATTCCGGGCAGCTTAGTGTCAGCCTTGCCAAA
AGCCTAAGCGAAAGCCTGCAAGAGACCTTATTGAGGACAACACGCCATTTTGCCAGCGGTCTCTTCGAAATGATCCTGAT
CCTTTTCTTTCTCCTTGTCTTTGGTGACATGTTCCTCCGGCGACTCGTAGAAATCTTGCCGCGTTTCAAGGACAAGCGGC
AGGTCGTCGATCTTTCCCAGCAGATCGAAAGCAATATTTCTGCTTATCTGCTGACCATCACAATCATGAATGCTGCCGTC
GGCCTTGCGACGGCGATCGTTATGTGGGCCTGTGGTGTCGGAGATCCGATTTTATGGGGACTCATCGCGTTTCTTTTGAA
TTTCCTGCCGATCATGGGGCCATTCTTCGGCGTTGGAGTGTTTCTTGTCGCAGGCTTGTTGACCATTCCGCAATTATGGC
TCGCGCTTTTGCCGGCGGGGCTTTATTTGCTCATCCATATTATGGAAGGGGAGTTGATTACTCCCATGCTGCTTGCGCGC
CGCTTTACGCTTAATCCCGTTTTGGTGATTGTGTCCCTCATCTTCTGGTTTTGGATGTGGGGTGTTCTTGGCGCGATCCT
TTCGGTGCCTTTGCTCGCGATGACGAAGATTATTTGCGATGGAATCAAGCCTCTCAACGCTGTCGGGCATTTTTTGGAAG
GAGATTCGCCTTGA

Upstream 100 bases:

>100_bases
AGTATAACGCATTGAGATTTGGCCTCGCGACTGCGGGGCGGAGGCTTTCCGCCAGAGGTCCAGCATTGGTAAGTTCGCTC
GGGTTGGATGGGTGGACCAA

Downstream 100 bases:

>100_bases
ACTTTGTGACATAATCCGGGCCTGTCTCAAGCTCTGCGAGAGGATGCAAGAAGGACCGGGGCCCCGACTTTTGCAGACTT
CATTAGCCATTCGGATTCCG

Product: hypothetical protein

Products: NA

Alternate protein names: Transport of quorum-sensing signal protein [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTSSREGVTPNAQAGAKELPDTADQNILPAQDPNTVLLAGLFLIAALSGAYVAAEVVLPLIFAIVLKLLLQPGMRFLERY
YIPRHLAAFFLILAVLGAILGIGAAVSGPSKAWFEHLSEGLPLLRERLLFLSHPFELLDTLRNKMDGMGHSGQLSVSLAK
SLSESLQETLLRTTRHFASGLFEMILILFFLLVFGDMFLRRLVEILPRFKDKRQVVDLSQQIESNISAYLLTITIMNAAV
GLATAIVMWACGVGDPILWGLIAFLLNFLPIMGPFFGVGVFLVAGLLTIPQLWLALLPAGLYLLIHIMEGELITPMLLAR
RFTLNPVLVIVSLIFWFWMWGVLGAILSVPLLAMTKIICDGIKPLNAVGHFLEGDSP

Sequences:

>Translated_377_residues
MTSSREGVTPNAQAGAKELPDTADQNILPAQDPNTVLLAGLFLIAALSGAYVAAEVVLPLIFAIVLKLLLQPGMRFLERY
YIPRHLAAFFLILAVLGAILGIGAAVSGPSKAWFEHLSEGLPLLRERLLFLSHPFELLDTLRNKMDGMGHSGQLSVSLAK
SLSESLQETLLRTTRHFASGLFEMILILFFLLVFGDMFLRRLVEILPRFKDKRQVVDLSQQIESNISAYLLTITIMNAAV
GLATAIVMWACGVGDPILWGLIAFLLNFLPIMGPFFGVGVFLVAGLLTIPQLWLALLPAGLYLLIHIMEGELITPMLLAR
RFTLNPVLVIVSLIFWFWMWGVLGAILSVPLLAMTKIICDGIKPLNAVGHFLEGDSP
>Mature_376_residues
TSSREGVTPNAQAGAKELPDTADQNILPAQDPNTVLLAGLFLIAALSGAYVAAEVVLPLIFAIVLKLLLQPGMRFLERYY
IPRHLAAFFLILAVLGAILGIGAAVSGPSKAWFEHLSEGLPLLRERLLFLSHPFELLDTLRNKMDGMGHSGQLSVSLAKS
LSESLQETLLRTTRHFASGLFEMILILFFLLVFGDMFLRRLVEILPRFKDKRQVVDLSQQIESNISAYLLTITIMNAAVG
LATAIVMWACGVGDPILWGLIAFLLNFLPIMGPFFGVGVFLVAGLLTIPQLWLALLPAGLYLLIHIMEGELITPMLLARR
FTLNPVLVIVSLIFWFWMWGVLGAILSVPLLAMTKIICDGIKPLNAVGHFLEGDSP

Specific function: Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [H]

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1787885, Length=315, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082271, Length=340, Percent_Identity=24.4117647058824, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 41309; Mature: 41178

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSREGVTPNAQAGAKELPDTADQNILPAQDPNTVLLAGLFLIAALSGAYVAAEVVLPL
CCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IFAIVLKLLLQPGMRFLERYYIPRHLAAFFLILAVLGAILGIGAAVSGPSKAWFEHLSEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
LPLLRERLLFLSHPFELLDTLRNKMDGMGHSGQLSVSLAKSLSESLQETLLRTTRHFASG
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFEMILILFFLLVFGDMFLRRLVEILPRFKDKRQVVDLSQQIESNISAYLLTITIMNAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLATAIVMWACGVGDPILWGLIAFLLNFLPIMGPFFGVGVFLVAGLLTIPQLWLALLPAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYLLIHIMEGELITPMLLARRFTLNPVLVIVSLIFWFWMWGVLGAILSVPLLAMTKIICD
HHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIKPLNAVGHFLEGDSP
CCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSSREGVTPNAQAGAKELPDTADQNILPAQDPNTVLLAGLFLIAALSGAYVAAEVVLPL
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IFAIVLKLLLQPGMRFLERYYIPRHLAAFFLILAVLGAILGIGAAVSGPSKAWFEHLSEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
LPLLRERLLFLSHPFELLDTLRNKMDGMGHSGQLSVSLAKSLSESLQETLLRTTRHFASG
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFEMILILFFLLVFGDMFLRRLVEILPRFKDKRQVVDLSQQIESNISAYLLTITIMNAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLATAIVMWACGVGDPILWGLIAFLLNFLPIMGPFFGVGVFLVAGLLTIPQLWLALLPAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYLLIHIMEGELITPMLLARRFTLNPVLVIVSLIFWFWMWGVLGAILSVPLLAMTKIICD
HHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIKPLNAVGHFLEGDSP
CCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]