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The map label for this gene is putA [H]

Identifier: 182679724

GI number: 182679724

Start: 3201587

End: 3204685

Strand: Reverse

Name: putA [H]

Synonym: Bind_2812

Alternate gene names: 182679724

Gene position: 3204685-3201587 (Counterclockwise)

Preceding gene: 182679725

Following gene: 182679708

Centisome position: 76.85

GC content: 57.41

Gene sequence:

>3099_bases
ATGACCTCCAGTTCGACATTCCTTCCTTTTTCAGCGCCTTATGCGCCTGCCGACGAGGCAATTGCCGAAGACCTGCTGAG
GCAGGTCGAATGTGACAAGGCCGTGCAAGCAAGGATTGATGCCCGGGCAACACGGCTCGTCCAGGCCGTTCGCGCGCGCG
CGTCGCGTCTTGGTGGTCTCGATGATCTCTTGCGCGAATATTCTCTTTCGACGCAGGAAGGTCTGGCCTTGATGGTGTTG
GCGGAAGCCTTGCTGCGCGTGCCGGACGATGCCACCGCTGATCGATTGATCGCCGACAAGCTCGCGTCCTTTCACGAGCA
TCGGAACCCTGCCGGGCAGGATCCTCTTTTGGTGAGCATGGCCGATTGGGCGCTTGGCGCCTCCGCGCATGTCCTGACGG
CTGGCCGATCGATGGAGGGGCTCGTCGCTTTTCTCGCCCGGCGGCTTGGACCGACGACGATCCGGATCGCGGCGCGCCGC
GCGATGCAGGTCCTTGGCAATCATTTCGTGCTTGGCCGTACGATCGAGGAAGGGCTGGCCAGGGCACATCTTGATCGCAG
CGAAAATTTCTATTCCTTCGACATGCTGGGGGAAGGCGCGCGCACTGCTGACGATGCCGCGCTCTATTATGACGCCTATG
CCCAGGCGATCGGGCGTTTGGGGCAGCGCGCCGGGACAAGGCCTTTGCCGGCCCGACCGGGCATTTCTGTCAAACTTTCT
GCCCTGCATCCCCGTTATGAAGCGCGCAAACGCACCACGATTTTGCCCGAACTGCTGCCGCGCATCAGCCAATTAGCCCG
GCTCGCCAAAACCCATGATCTGAATTTCACGATAGATGCCGAAGAAGCCGACCGGCTCGAATTCTCGCTCGATCTTGTCG
ATGCCTTGTTGCGTGACCCGGACCTTGCGGGTTGGAAAGGGTTTGGCCTCGCGGTGCAAGCCTATCAGAAACGCGCGGGG
ACCGTGATCGACCATGTCGTGACAAGCGCGCGCCAGCAGGGTCGACAGATCATGGTCAGGCTGGTCAAAGGCGCTTATTG
GGATACGGAAATTAAGCGTGCTCAAGAGCGTGGCCTTGCCGATTATCCAGTCTTTACCCGCAAGGCCATGACGGATTTGA
ATTATATTGCTTGTGCCAAGCTTTTGCTTGCGGCGCGTGATTGTGTCTATCCACAATTTGCCACGCATAATGCCCTGACA
ATCGCCACGATTATCGAACTCGCCACGGGGGCTGGTGCTTATGAATTTCAGCGCCTCCAAGGCATGGGCGAAGATCTCTA
TACAGCCTTGCGGGAAGACAGGTCGGACAGCCGTTGCCGTGTCTATGCGCCAATTGGGGCGCATGAACATCTGCTTCCTT
ATCTCGTGCGCAGACTTCTGGAGAATGGGGCCAATTCCTCCTTCGTATCGCGGATCGGTGATCCGAATGTGCCAGTCAAG
GATCTGCTCATCCGCCCTCAAACTGTGATCGGGCAAGCGGCCAATGCAAGATCTCAGCATCTTCCTTTGCCGTGCGATCT
CCATGCGCCTGACCGAAAAACAGCGCAAGGGCTTGAATTTGGGGACAGAAAATCGGTGACGGTACTGCTGCGTCGAATTG
GCGAGACGCGTTCGGCCTTGCAGTCCGCGCGGGGCCACAAGAGAACTCCCCGGACAGGGGATGTCTTGCTCGTTTCTTCA
CCCATTGATGGCACGATCATCGGGGAAGTGAATGAAGCGCAGCGTGATCTCTTGCCGGACATCCTCCGCGTGGCCAAGGA
GGGGTTTCGCGTATGGTCGCGGACACCCGTGCGCGAACGGGCAGCTTGCCTTGATCGCTGCGCGGCACGTCTCGTGGCCG
AGGCGCCCGAGATCCTGTGCTTGCTCCAGAAAGAAGCCGGTAAAACGCTCGAAGATGCTGTGGGTGAATGGCGGGAGGCG
ATCGACTTCTGCCGCTATTACGCGGCCGAAGCCCGGCATCATCTTAGCGACGGTGTATTCATGCCGGGACCCACGGGAGA
ACAGAACCAGCTTCGCAAACTGGGCCGTGGTGTTTTCGTTTGTATCAGTCCATGGAATTTTCCTTTGTCGATCTTCCTTG
GCCAGGTCGCGGCGGCCCTTGTCGCGGGAAATAGCGTTCTCGCCAAACCCGCCGAACAAACACCGTTGATCGCCGCTAAA
ATCGTAGCCCTTCTACATGACTGCGGTGTTCCTGCGTCGGTGCTGCATGTGCTTCAAGGTGACGGCAAGATTGGCGAAGC
GCTTGTCGCCTTGCCGGACATTGCAGGCGTCGCTTTCACTGGGTCGAGCGCGGTGGCCTCCCATATTAATCGCGCCTTGG
CGGCCAAGCAGGGGCCGATTGCATGTCTGATCGCGGAAACTGGCGGAATCAATGCGATGATCGTCGATGCGACAGCGCAA
TTGGAACAGGTTTGCGATGATGTTCTGACCTCGGCTTTTCGTTCGGCGGGCCAGAGGTGTTCATCTTTGCGATTGCTTTG
CTTACAGGAGGAGATTGCCGATGATGCTTTGAGCCTGATCCGTGGTGGAGTTGAGGAATTGTCTGTTGATGATCCATTGG
ATCTCGGTACGGATATCGGACCGATCATCGATGCGTCAGCCCATCGAACATTGACAGACCATATTGAAATGATGCGGCGA
GAGAAGCGGCTTCTCTGTCACGGAAAAGTGTCGGCCGGCGCGCCCAAGGCGGGCTTTTATCTTGCTCCCCATATTATCGA
GTTGAAGCGAGCCGAGGATCTAGACCGAGAGGTTTTTGGGCCAATCCTGCATGTCGTGCGCTATAAAAATGAGGATCTGA
GCAAACTTCTCGATGAGCTCGAAGACAAGGGATATGGTCTGACGATGGGGATCCATTCCCGTATCAACGCAACGATCGAA
CAAATCTGCGCGCGCAGGCTCGCGGGAAATGTCTACATCAATCGCAATATGATCGGTGCCGTGGTGGGGACCCAGCCTTT
TGGGGGATTTGGTCTCTCGGGTACGGGGCCGAAGGCCGGGGGCCCTTCCTATCTCGATCGATTTTGCGTCGAAACAATTG
TCACGACCAATATGACCGCGGTCGGTGGGGACATTAAACTCATCAATTCCTTGTCTTGA

Upstream 100 bases:

>100_bases
CGCGTTTTTGAAGGCCGATCAGGCGTGAGACAGAACTCGGGAGGGTGCCCCCGAGTTCTGTTTTTTATTAGGACCAAGGA
TCGGATGGGAAAGGCATGCG

Downstream 100 bases:

>100_bases
TCTTCATGCTTTAGAGCCCATCTTTTTAAATAGAAGCTGGAACACTTGCTTTAGACCCAAAAGTAGCCCCCCCCCTTTTT
GTGATGCATTTTCAGAAAGA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1032; Mature: 1031

Protein sequence:

>1032_residues
MTSSSTFLPFSAPYAPADEAIAEDLLRQVECDKAVQARIDARATRLVQAVRARASRLGGLDDLLREYSLSTQEGLALMVL
AEALLRVPDDATADRLIADKLASFHEHRNPAGQDPLLVSMADWALGASAHVLTAGRSMEGLVAFLARRLGPTTIRIAARR
AMQVLGNHFVLGRTIEEGLARAHLDRSENFYSFDMLGEGARTADDAALYYDAYAQAIGRLGQRAGTRPLPARPGISVKLS
ALHPRYEARKRTTILPELLPRISQLARLAKTHDLNFTIDAEEADRLEFSLDLVDALLRDPDLAGWKGFGLAVQAYQKRAG
TVIDHVVTSARQQGRQIMVRLVKGAYWDTEIKRAQERGLADYPVFTRKAMTDLNYIACAKLLLAARDCVYPQFATHNALT
IATIIELATGAGAYEFQRLQGMGEDLYTALREDRSDSRCRVYAPIGAHEHLLPYLVRRLLENGANSSFVSRIGDPNVPVK
DLLIRPQTVIGQAANARSQHLPLPCDLHAPDRKTAQGLEFGDRKSVTVLLRRIGETRSALQSARGHKRTPRTGDVLLVSS
PIDGTIIGEVNEAQRDLLPDILRVAKEGFRVWSRTPVRERAACLDRCAARLVAEAPEILCLLQKEAGKTLEDAVGEWREA
IDFCRYYAAEARHHLSDGVFMPGPTGEQNQLRKLGRGVFVCISPWNFPLSIFLGQVAAALVAGNSVLAKPAEQTPLIAAK
IVALLHDCGVPASVLHVLQGDGKIGEALVALPDIAGVAFTGSSAVASHINRALAAKQGPIACLIAETGGINAMIVDATAQ
LEQVCDDVLTSAFRSAGQRCSSLRLLCLQEEIADDALSLIRGGVEELSVDDPLDLGTDIGPIIDASAHRTLTDHIEMMRR
EKRLLCHGKVSAGAPKAGFYLAPHIIELKRAEDLDREVFGPILHVVRYKNEDLSKLLDELEDKGYGLTMGIHSRINATIE
QICARRLAGNVYINRNMIGAVVGTQPFGGFGLSGTGPKAGGPSYLDRFCVETIVTTNMTAVGGDIKLINSLS

Sequences:

>Translated_1032_residues
MTSSSTFLPFSAPYAPADEAIAEDLLRQVECDKAVQARIDARATRLVQAVRARASRLGGLDDLLREYSLSTQEGLALMVL
AEALLRVPDDATADRLIADKLASFHEHRNPAGQDPLLVSMADWALGASAHVLTAGRSMEGLVAFLARRLGPTTIRIAARR
AMQVLGNHFVLGRTIEEGLARAHLDRSENFYSFDMLGEGARTADDAALYYDAYAQAIGRLGQRAGTRPLPARPGISVKLS
ALHPRYEARKRTTILPELLPRISQLARLAKTHDLNFTIDAEEADRLEFSLDLVDALLRDPDLAGWKGFGLAVQAYQKRAG
TVIDHVVTSARQQGRQIMVRLVKGAYWDTEIKRAQERGLADYPVFTRKAMTDLNYIACAKLLLAARDCVYPQFATHNALT
IATIIELATGAGAYEFQRLQGMGEDLYTALREDRSDSRCRVYAPIGAHEHLLPYLVRRLLENGANSSFVSRIGDPNVPVK
DLLIRPQTVIGQAANARSQHLPLPCDLHAPDRKTAQGLEFGDRKSVTVLLRRIGETRSALQSARGHKRTPRTGDVLLVSS
PIDGTIIGEVNEAQRDLLPDILRVAKEGFRVWSRTPVRERAACLDRCAARLVAEAPEILCLLQKEAGKTLEDAVGEWREA
IDFCRYYAAEARHHLSDGVFMPGPTGEQNQLRKLGRGVFVCISPWNFPLSIFLGQVAAALVAGNSVLAKPAEQTPLIAAK
IVALLHDCGVPASVLHVLQGDGKIGEALVALPDIAGVAFTGSSAVASHINRALAAKQGPIACLIAETGGINAMIVDATAQ
LEQVCDDVLTSAFRSAGQRCSSLRLLCLQEEIADDALSLIRGGVEELSVDDPLDLGTDIGPIIDASAHRTLTDHIEMMRR
EKRLLCHGKVSAGAPKAGFYLAPHIIELKRAEDLDREVFGPILHVVRYKNEDLSKLLDELEDKGYGLTMGIHSRINATIE
QICARRLAGNVYINRNMIGAVVGTQPFGGFGLSGTGPKAGGPSYLDRFCVETIVTTNMTAVGGDIKLINSLS
>Mature_1031_residues
TSSSTFLPFSAPYAPADEAIAEDLLRQVECDKAVQARIDARATRLVQAVRARASRLGGLDDLLREYSLSTQEGLALMVLA
EALLRVPDDATADRLIADKLASFHEHRNPAGQDPLLVSMADWALGASAHVLTAGRSMEGLVAFLARRLGPTTIRIAARRA
MQVLGNHFVLGRTIEEGLARAHLDRSENFYSFDMLGEGARTADDAALYYDAYAQAIGRLGQRAGTRPLPARPGISVKLSA
LHPRYEARKRTTILPELLPRISQLARLAKTHDLNFTIDAEEADRLEFSLDLVDALLRDPDLAGWKGFGLAVQAYQKRAGT
VIDHVVTSARQQGRQIMVRLVKGAYWDTEIKRAQERGLADYPVFTRKAMTDLNYIACAKLLLAARDCVYPQFATHNALTI
ATIIELATGAGAYEFQRLQGMGEDLYTALREDRSDSRCRVYAPIGAHEHLLPYLVRRLLENGANSSFVSRIGDPNVPVKD
LLIRPQTVIGQAANARSQHLPLPCDLHAPDRKTAQGLEFGDRKSVTVLLRRIGETRSALQSARGHKRTPRTGDVLLVSSP
IDGTIIGEVNEAQRDLLPDILRVAKEGFRVWSRTPVRERAACLDRCAARLVAEAPEILCLLQKEAGKTLEDAVGEWREAI
DFCRYYAAEARHHLSDGVFMPGPTGEQNQLRKLGRGVFVCISPWNFPLSIFLGQVAAALVAGNSVLAKPAEQTPLIAAKI
VALLHDCGVPASVLHVLQGDGKIGEALVALPDIAGVAFTGSSAVASHINRALAAKQGPIACLIAETGGINAMIVDATAQL
EQVCDDVLTSAFRSAGQRCSSLRLLCLQEEIADDALSLIRGGVEELSVDDPLDLGTDIGPIIDASAHRTLTDHIEMMRRE
KRLLCHGKVSAGAPKAGFYLAPHIIELKRAEDLDREVFGPILHVVRYKNEDLSKLLDELEDKGYGLTMGIHSRINATIEQ
ICARRLAGNVYINRNMIGAVVGTQPFGGFGLSGTGPKAGGPSYLDRFCVETIVTTNMTAVGGDIKLINSLS

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=491, Percent_Identity=28.7169042769857, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI25777734, Length=491, Percent_Identity=28.7169042769857, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI238859541, Length=491, Percent_Identity=28.7169042769857, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI25777724, Length=468, Percent_Identity=30.1282051282051, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI25777730, Length=454, Percent_Identity=28.4140969162996, Blast_Score=160, Evalue=8e-39,
Organism=Homo sapiens, GI21614513, Length=474, Percent_Identity=28.9029535864979, Blast_Score=158, Evalue=3e-38,
Organism=Homo sapiens, GI12007648, Length=474, Percent_Identity=28.2700421940928, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI115387104, Length=463, Percent_Identity=26.5658747300216, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI238814322, Length=462, Percent_Identity=28.3549783549784, Blast_Score=151, Evalue=3e-36,
Organism=Homo sapiens, GI21361176, Length=483, Percent_Identity=27.3291925465839, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI153266822, Length=331, Percent_Identity=29.607250755287, Blast_Score=147, Evalue=7e-35,
Organism=Homo sapiens, GI25777728, Length=332, Percent_Identity=31.9277108433735, Blast_Score=145, Evalue=3e-34,
Organism=Homo sapiens, GI25777732, Length=452, Percent_Identity=25.2212389380531, Blast_Score=145, Evalue=3e-34,
Organism=Homo sapiens, GI188035924, Length=461, Percent_Identity=25.8134490238612, Blast_Score=136, Evalue=8e-32,
Organism=Homo sapiens, GI310128093, Length=461, Percent_Identity=25.8134490238612, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI310128103, Length=461, Percent_Identity=25.8134490238612, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI25952152, Length=462, Percent_Identity=26.4069264069264, Blast_Score=130, Evalue=5e-30,
Organism=Homo sapiens, GI4507229, Length=461, Percent_Identity=25.8134490238612, Blast_Score=130, Evalue=8e-30,
Organism=Homo sapiens, GI25777726, Length=467, Percent_Identity=27.4089935760171, Blast_Score=127, Evalue=8e-29,
Organism=Homo sapiens, GI11095441, Length=422, Percent_Identity=27.2511848341232, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI310128091, Length=461, Percent_Identity=24.9457700650759, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI25777721, Length=474, Percent_Identity=24.8945147679325, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI4502043, Length=447, Percent_Identity=25.2796420581655, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI238814371, Length=447, Percent_Identity=25.2796420581655, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI71773324, Length=338, Percent_Identity=25.4437869822485, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI310128087, Length=281, Percent_Identity=27.0462633451957, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI73695881, Length=340, Percent_Identity=26.1764705882353, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI73695879, Length=340, Percent_Identity=26.1764705882353, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI206597441, Length=331, Percent_Identity=23.8670694864048, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI206597439, Length=331, Percent_Identity=23.8670694864048, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI22907049, Length=331, Percent_Identity=23.8670694864048, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI310128089, Length=326, Percent_Identity=25.1533742331288, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI73466520, Length=332, Percent_Identity=24.0963855421687, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI4557303, Length=336, Percent_Identity=24.4047619047619, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI301500698, Length=284, Percent_Identity=26.056338028169, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI310128095, Length=313, Percent_Identity=26.1980830670927, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI310128099, Length=222, Percent_Identity=25.6756756756757, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI310128101, Length=222, Percent_Identity=25.6756756756757, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI310128097, Length=252, Percent_Identity=26.5873015873016, Blast_Score=75, Evalue=4e-13,
Organism=Escherichia coli, GI1787250, Length=1028, Percent_Identity=45.2334630350195, Blast_Score=812, Evalue=0.0,
Organism=Escherichia coli, GI1788042, Length=452, Percent_Identity=30.9734513274336, Blast_Score=174, Evalue=3e-44,
Organism=Escherichia coli, GI1789015, Length=464, Percent_Identity=28.8793103448276, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1787715, Length=470, Percent_Identity=31.063829787234, Blast_Score=165, Evalue=1e-41,
Organism=Escherichia coli, GI1787558, Length=416, Percent_Identity=31.7307692307692, Blast_Score=156, Evalue=6e-39,
Organism=Escherichia coli, GI87081896, Length=466, Percent_Identity=28.9699570815451, Blast_Score=154, Evalue=3e-38,
Organism=Escherichia coli, GI1787684, Length=451, Percent_Identity=28.8248337028825, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI1786504, Length=471, Percent_Identity=27.1762208067941, Blast_Score=141, Evalue=3e-34,
Organism=Escherichia coli, GI87082295, Length=465, Percent_Identity=28.8172043010753, Blast_Score=129, Evalue=9e-31,
Organism=Escherichia coli, GI87081926, Length=456, Percent_Identity=27.1929824561404, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1787653, Length=415, Percent_Identity=22.4096385542169, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562198, Length=462, Percent_Identity=29.004329004329, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI133930964, Length=448, Percent_Identity=28.3482142857143, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI25144435, Length=460, Percent_Identity=26.9565217391304, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25143876, Length=448, Percent_Identity=26.3392857142857, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=448, Percent_Identity=26.3392857142857, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17534447, Length=463, Percent_Identity=27.8617710583153, Blast_Score=149, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71995606, Length=460, Percent_Identity=26.5217391304348, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17534119, Length=480, Percent_Identity=27.5, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI115534176, Length=487, Percent_Identity=26.2833675564682, Blast_Score=143, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI115532534, Length=383, Percent_Identity=29.7650130548303, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=425, Percent_Identity=27.2941176470588, Blast_Score=137, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI32564736, Length=368, Percent_Identity=29.0760869565217, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71995613, Length=417, Percent_Identity=25.1798561151079, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71986308, Length=435, Percent_Identity=26.2068965517241, Blast_Score=125, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32564151, Length=411, Percent_Identity=25.7907542579075, Blast_Score=110, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25146391, Length=348, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=348, Percent_Identity=25, Blast_Score=98, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=348, Percent_Identity=25, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=325, Percent_Identity=23.3846153846154, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=26.4900662251656, Blast_Score=81, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320917, Length=464, Percent_Identity=30.1724137931034, Blast_Score=167, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6324950, Length=439, Percent_Identity=28.4738041002278, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323822, Length=480, Percent_Identity=27.9166666666667, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323821, Length=462, Percent_Identity=28.7878787878788, Blast_Score=154, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6325196, Length=460, Percent_Identity=28.4782608695652, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321826, Length=444, Percent_Identity=28.1531531531532, Blast_Score=144, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6319478, Length=476, Percent_Identity=26.890756302521, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321828, Length=560, Percent_Identity=23.2142857142857, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323757, Length=341, Percent_Identity=26.3929618768328, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362580, Length=461, Percent_Identity=28.6334056399132, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI62472918, Length=461, Percent_Identity=28.6334056399132, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI62472926, Length=461, Percent_Identity=28.6334056399132, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI62472936, Length=461, Percent_Identity=28.6334056399132, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI21356737, Length=461, Percent_Identity=28.6334056399132, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24668425, Length=457, Percent_Identity=26.9146608315098, Blast_Score=153, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24668417, Length=457, Percent_Identity=26.9146608315098, Blast_Score=153, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24668413, Length=457, Percent_Identity=26.9146608315098, Blast_Score=153, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24650465, Length=476, Percent_Identity=26.890756302521, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI20129399, Length=460, Percent_Identity=25.6521739130435, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24666674, Length=477, Percent_Identity=28.0922431865828, Blast_Score=141, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24585660, Length=474, Percent_Identity=26.3713080168776, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28574525, Length=462, Percent_Identity=25.1082251082251, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571798, Length=466, Percent_Identity=26.6094420600858, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571796, Length=466, Percent_Identity=26.6094420600858, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571794, Length=466, Percent_Identity=26.6094420600858, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571806, Length=466, Percent_Identity=26.6094420600858, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28571802, Length=466, Percent_Identity=26.6094420600858, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28571800, Length=466, Percent_Identity=26.6094420600858, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638878, Length=431, Percent_Identity=25.5220417633411, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24638876, Length=431, Percent_Identity=25.754060324826, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI45552499, Length=359, Percent_Identity=23.6768802228412, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281360303, Length=359, Percent_Identity=23.6768802228412, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281360301, Length=359, Percent_Identity=23.3983286908078, Blast_Score=74, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281360299, Length=359, Percent_Identity=23.3983286908078, Blast_Score=74, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281360297, Length=359, Percent_Identity=23.3983286908078, Blast_Score=74, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281360295, Length=359, Percent_Identity=23.3983286908078, Blast_Score=74, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24586250, Length=359, Percent_Identity=23.3983286908078, Blast_Score=74, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 112110; Mature: 111979

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSSTFLPFSAPYAPADEAIAEDLLRQVECDKAVQARIDARATRLVQAVRARASRLGGL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DDLLREYSLSTQEGLALMVLAEALLRVPDDATADRLIADKLASFHEHRNPAGQDPLLVSM
HHHHHHHCCCHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ADWALGASAHVLTAGRSMEGLVAFLARRLGPTTIRIAARRAMQVLGNHFVLGRTIEEGLA
HHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEHHHHHHHHH
RAHLDRSENFYSFDMLGEGARTADDAALYYDAYAQAIGRLGQRAGTRPLPARPGISVKLS
HHHCCCCCCEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
ALHPRYEARKRTTILPELLPRISQLARLAKTHDLNFTIDAEEADRLEFSLDLVDALLRDP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCC
DLAGWKGFGLAVQAYQKRAGTVIDHVVTSARQQGRQIMVRLVKGAYWDTEIKRAQERGLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
DYPVFTRKAMTDLNYIACAKLLLAARDCVYPQFATHNALTIATIIELATGAGAYEFQRLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
GMGEDLYTALREDRSDSRCRVYAPIGAHEHLLPYLVRRLLENGANSSFVSRIGDPNVPVK
CCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHH
DLLIRPQTVIGQAANARSQHLPLPCDLHAPDRKTAQGLEFGDRKSVTVLLRRIGETRSAL
HHHCCCHHHHCCHHCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
QSARGHKRTPRTGDVLLVSSPIDGTIIGEVNEAQRDLLPDILRVAKEGFRVWSRTPVRER
HHHCCCCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AACLDRCAARLVAEAPEILCLLQKEAGKTLEDAVGEWREAIDFCRYYAAEARHHLSDGVF
HHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MPGPTGEQNQLRKLGRGVFVCISPWNFPLSIFLGQVAAALVAGNSVLAKPAEQTPLIAAK
CCCCCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
IVALLHDCGVPASVLHVLQGDGKIGEALVALPDIAGVAFTGSSAVASHINRALAAKQGPI
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHCCCCE
ACLIAETGGINAMIVDATAQLEQVCDDVLTSAFRSAGQRCSSLRLLCLQEEIADDALSLI
EEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGGVEELSVDDPLDLGTDIGPIIDASAHRTLTDHIEMMRREKRLLCHGKVSAGAPKAGFY
HCCHHHCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
LAPHIIELKRAEDLDREVFGPILHVVRYKNEDLSKLLDELEDKGYGLTMGIHSRINATIE
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHH
QICARRLAGNVYINRNMIGAVVGTQPFGGFGLSGTGPKAGGPSYLDRFCVETIVTTNMTA
HHHHHHHHCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
VGGDIKLINSLS
CCCCCHHHCCCC
>Mature Secondary Structure 
TSSSTFLPFSAPYAPADEAIAEDLLRQVECDKAVQARIDARATRLVQAVRARASRLGGL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DDLLREYSLSTQEGLALMVLAEALLRVPDDATADRLIADKLASFHEHRNPAGQDPLLVSM
HHHHHHHCCCHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ADWALGASAHVLTAGRSMEGLVAFLARRLGPTTIRIAARRAMQVLGNHFVLGRTIEEGLA
HHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEHHHHHHHHH
RAHLDRSENFYSFDMLGEGARTADDAALYYDAYAQAIGRLGQRAGTRPLPARPGISVKLS
HHHCCCCCCEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
ALHPRYEARKRTTILPELLPRISQLARLAKTHDLNFTIDAEEADRLEFSLDLVDALLRDP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCC
DLAGWKGFGLAVQAYQKRAGTVIDHVVTSARQQGRQIMVRLVKGAYWDTEIKRAQERGLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
DYPVFTRKAMTDLNYIACAKLLLAARDCVYPQFATHNALTIATIIELATGAGAYEFQRLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
GMGEDLYTALREDRSDSRCRVYAPIGAHEHLLPYLVRRLLENGANSSFVSRIGDPNVPVK
CCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHH
DLLIRPQTVIGQAANARSQHLPLPCDLHAPDRKTAQGLEFGDRKSVTVLLRRIGETRSAL
HHHCCCHHHHCCHHCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
QSARGHKRTPRTGDVLLVSSPIDGTIIGEVNEAQRDLLPDILRVAKEGFRVWSRTPVRER
HHHCCCCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AACLDRCAARLVAEAPEILCLLQKEAGKTLEDAVGEWREAIDFCRYYAAEARHHLSDGVF
HHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MPGPTGEQNQLRKLGRGVFVCISPWNFPLSIFLGQVAAALVAGNSVLAKPAEQTPLIAAK
CCCCCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
IVALLHDCGVPASVLHVLQGDGKIGEALVALPDIAGVAFTGSSAVASHINRALAAKQGPI
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHCCCCE
ACLIAETGGINAMIVDATAQLEQVCDDVLTSAFRSAGQRCSSLRLLCLQEEIADDALSLI
EEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGGVEELSVDDPLDLGTDIGPIIDASAHRTLTDHIEMMRREKRLLCHGKVSAGAPKAGFY
HCCHHHCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
LAPHIIELKRAEDLDREVFGPILHVVRYKNEDLSKLLDELEDKGYGLTMGIHSRINATIE
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHH
QICARRLAGNVYINRNMIGAVVGTQPFGGFGLSGTGPKAGGPSYLDRFCVETIVTTNMTA
HHHHHHHHCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
VGGDIKLINSLS
CCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]