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The map label for this gene is sdhB [H]

Identifier: 182679662

GI number: 182679662

Start: 3131933

End: 3132712

Strand: Reverse

Name: sdhB [H]

Synonym: Bind_2747

Alternate gene names: 182679662

Gene position: 3132712-3131933 (Counterclockwise)

Preceding gene: 182679663

Following gene: 182679661

Centisome position: 75.12

GC content: 54.62

Gene sequence:

>780_bases
ATGGTTCAGTTTACCCTCCCTAAAAATTCGACGGTGACGACAGGCAAGACATGGCCGAAGCCGGCTGGAGCCAAAAACGT
CAAGGAATATCACATCTATCGCTGGAACCCAGAGGATGGAGCCAATCCGCGCATCGATACTTATTTCGTCGATCGTGACA
ATTGTGCGCCGATGGTTCTCGATGCCTTGATCTATATCAAGTCAAATATCGATCCGACGCTGACCTTCCGCCGTTCCTGC
CGCGAAGGCATTTGTGGCTCATGCGCCATGAATATTGACGGCACCAATACTCTTGCCTGCACCAAAGGCATGGATGAGGT
CAAAGGGGCGGTAAAGATCTATCCTTTGCCGCATATGATGGTGGTCAAGGATCTCGTGCCGGATCTGACCAATTTCTATG
CGCAGCATGCTTCGATTGAGCCTTGGCTCAAGACGACGACGCCGGCTCCGGAAAAGGAATGGCGGCAATCGCCTGAGGAT
CGCAGCAAGCTCGACGGCCTTTATGAGTGCATCCTCTGCGCCTGTTGCTCGACCTCATGCCCGAGCTATTGGTGGAATGG
TGACCGTTATCTCGGTCCTGCCGCGCTCCTCCAGGCCTATCGTTGGTTGATCGACTCTCGCGATGAAACCACGGGTGAGC
GTCTCGATAATGTCGAGGATCCGTTCCGGCTCTACCGCTGCCACACCATCATGAATTGCGCCAAGGCTTGCCCCAAGGGG
CTCAACCCTGCCAAAGCCATCGCCGAAATCAAGACGATGATGATCGAGCGCCAGCTCTGA

Upstream 100 bases:

>100_bases
CAGGTGGAATGGAACGGCGATCATGCATGGGATCTTGCCTGGTCTCAAACAGACGGTGAACCGGCATTCTTTGCGGCTGA
AATTCTAAAGGTTCTTCATC

Downstream 100 bases:

>100_bases
TCCGAGAAATATCTCTCTGAATTGAAGGCACTTTCTCGAATTTCTGCCAATCTGTTGAGAAGGCAGAAATTCGAGAATCC
TCAGTCGTCATCTCTCGTGA

Product: succinate dehydrogenase and fumarate reductase iron-sulfur protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MVQFTLPKNSTVTTGKTWPKPAGAKNVKEYHIYRWNPEDGANPRIDTYFVDRDNCAPMVLDALIYIKSNIDPTLTFRRSC
REGICGSCAMNIDGTNTLACTKGMDEVKGAVKIYPLPHMMVVKDLVPDLTNFYAQHASIEPWLKTTTPAPEKEWRQSPED
RSKLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQAYRWLIDSRDETTGERLDNVEDPFRLYRCHTIMNCAKACPKG
LNPAKAIAEIKTMMIERQL

Sequences:

>Translated_259_residues
MVQFTLPKNSTVTTGKTWPKPAGAKNVKEYHIYRWNPEDGANPRIDTYFVDRDNCAPMVLDALIYIKSNIDPTLTFRRSC
REGICGSCAMNIDGTNTLACTKGMDEVKGAVKIYPLPHMMVVKDLVPDLTNFYAQHASIEPWLKTTTPAPEKEWRQSPED
RSKLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQAYRWLIDSRDETTGERLDNVEDPFRLYRCHTIMNCAKACPKG
LNPAKAIAEIKTMMIERQL
>Mature_259_residues
MVQFTLPKNSTVTTGKTWPKPAGAKNVKEYHIYRWNPEDGANPRIDTYFVDRDNCAPMVLDALIYIKSNIDPTLTFRRSC
REGICGSCAMNIDGTNTLACTKGMDEVKGAVKIYPLPHMMVVKDLVPDLTNFYAQHASIEPWLKTTTPAPEKEWRQSPED
RSKLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQAYRWLIDSRDETTGERLDNVEDPFRLYRCHTIMNCAKACPKG
LNPAKAIAEIKTMMIERQL

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=237, Percent_Identity=67.9324894514768, Blast_Score=342, Evalue=2e-94,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=52.5641025641026, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1790596, Length=232, Percent_Identity=33.6206896551724, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17533915, Length=232, Percent_Identity=64.2241379310345, Blast_Score=320, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6322987, Length=228, Percent_Identity=64.4736842105263, Blast_Score=309, Evalue=3e-85,
Organism=Drosophila melanogaster, GI17137106, Length=245, Percent_Identity=64.0816326530612, Blast_Score=342, Evalue=2e-94,
Organism=Drosophila melanogaster, GI24643156, Length=233, Percent_Identity=60.9442060085837, Blast_Score=309, Evalue=1e-84,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29372; Mature: 29372

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQFTLPKNSTVTTGKTWPKPAGAKNVKEYHIYRWNPEDGANPRIDTYFVDRDNCAPMVL
CEEEECCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHH
DALIYIKSNIDPTLTFRRSCREGICGSCAMNIDGTNTLACTKGMDEVKGAVKIYPLPHMM
HHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCHHHHCCCEEEECCCHHH
VVKDLVPDLTNFYAQHASIEPWLKTTTPAPEKEWRQSPEDRSKLDGLYECILCACCSTSC
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGDRYLGPAALLQAYRWLIDSRDETTGERLDNVEDPFRLYRCHTIMNCAKACPKG
CCCCCCCCCEECHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
LNPAKAIAEIKTMMIERQL
CCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVQFTLPKNSTVTTGKTWPKPAGAKNVKEYHIYRWNPEDGANPRIDTYFVDRDNCAPMVL
CEEEECCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHH
DALIYIKSNIDPTLTFRRSCREGICGSCAMNIDGTNTLACTKGMDEVKGAVKIYPLPHMM
HHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCHHHHCCCEEEECCCHHH
VVKDLVPDLTNFYAQHASIEPWLKTTTPAPEKEWRQSPEDRSKLDGLYECILCACCSTSC
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGDRYLGPAALLQAYRWLIDSRDETTGERLDNVEDPFRLYRCHTIMNCAKACPKG
CCCCCCCCCEECHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
LNPAKAIAEIKTMMIERQL
CCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA