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The map label for this gene is dhaR [H]

Identifier: 182679503

GI number: 182679503

Start: 2921833

End: 2922405

Strand: Reverse

Name: dhaR [H]

Synonym: Bind_2558

Alternate gene names: 182679503

Gene position: 2922405-2921833 (Counterclockwise)

Preceding gene: 182679504

Following gene: 182679496

Centisome position: 70.08

GC content: 53.4

Gene sequence:

>573_bases
ATGGCTCGACCCAGTCTGCGTGAAAAGATCATCGACGCGGCCCTGGAATGTTTTCATGAGCAAGGTTTCCTTGGATGCAG
CGTCCAGGACATCACCGACGCCGCCGGTGCACCCAAGGGATCATTCTACAATCATTTCAAAACCAAAGAGGCTCTGGCTC
TCGAAGTGTTGCAGCGTTATGTCGACGCAGTTCGTGTCGGTATGCTCTTCGAGGGTGATAGGCCACCACTCGAGCGATTG
CGCGCGCATTTCGAATATCTCATAGAGCGAAATAAGGATTTGGATTTTGCGCGCGGATGCATGATCGCCAATTTTACTTC
GGAAATGGCAGACCATTATCCAGATATGCGCACCGCCTTGGATCACGCCATGACGCGATGGAGCACCGCCATCACCTCCC
TATTGCGTCAGGCGCAAATCGACGGAAAGCTCTCGCAGGCCAAGGACCCTGAACGTCTGGCGCGTTTCATGATCTGTGCT
TGGCAGGGCACTCTCATGCGTGCACGAATCGCCAAAATCCACCAACCTTTCGATGATTTTTTTGCCCTGATCTTCGAGGA
TCTGCTGGCGTGA

Upstream 100 bases:

>100_bases
CAAACATTGCATCGGAAAAAGGCGCCTGACTGATGCTTGATCATCCCGAAAAATGCTTCTATTTAATATGACCAGTCAGA
TAAATAAGGAAGGAAGCGGG

Downstream 100 bases:

>100_bases
TGAGCGATTCAGGCGCATCGTAAATTTTGTATACGAACACATGGAAGCGTTTGTGTCCGTGGTTTTATGCTTTGCTAGTT
GTTTAGTCCCGGCATGTGAT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MARPSLREKIIDAALECFHEQGFLGCSVQDITDAAGAPKGSFYNHFKTKEALALEVLQRYVDAVRVGMLFEGDRPPLERL
RAHFEYLIERNKDLDFARGCMIANFTSEMADHYPDMRTALDHAMTRWSTAITSLLRQAQIDGKLSQAKDPERLARFMICA
WQGTLMRARIAKIHQPFDDFFALIFEDLLA

Sequences:

>Translated_190_residues
MARPSLREKIIDAALECFHEQGFLGCSVQDITDAAGAPKGSFYNHFKTKEALALEVLQRYVDAVRVGMLFEGDRPPLERL
RAHFEYLIERNKDLDFARGCMIANFTSEMADHYPDMRTALDHAMTRWSTAITSLLRQAQIDGKLSQAKDPERLARFMICA
WQGTLMRARIAKIHQPFDDFFALIFEDLLA
>Mature_189_residues
ARPSLREKIIDAALECFHEQGFLGCSVQDITDAAGAPKGSFYNHFKTKEALALEVLQRYVDAVRVGMLFEGDRPPLERLR
AHFEYLIERNKDLDFARGCMIANFTSEMADHYPDMRTALDHAMTRWSTAITSLLRQAQIDGKLSQAKDPERLARFMICAW
QGTLMRARIAKIHQPFDDFFALIFEDLLA

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=185, Percent_Identity=24.8648648648649, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21730; Mature: 21599

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPSLREKIIDAALECFHEQGFLGCSVQDITDAAGAPKGSFYNHFKTKEALALEVLQRY
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VDAVRVGMLFEGDRPPLERLRAHFEYLIERNKDLDFARGCMIANFTSEMADHYPDMRTAL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
DHAMTRWSTAITSLLRQAQIDGKLSQAKDPERLARFMICAWQGTLMRARIAKIHQPFDDF
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FALIFEDLLA
HHHHHHHHHC
>Mature Secondary Structure 
ARPSLREKIIDAALECFHEQGFLGCSVQDITDAAGAPKGSFYNHFKTKEALALEVLQRY
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VDAVRVGMLFEGDRPPLERLRAHFEYLIERNKDLDFARGCMIANFTSEMADHYPDMRTAL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
DHAMTRWSTAITSLLRQAQIDGKLSQAKDPERLARFMICAWQGTLMRARIAKIHQPFDDF
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FALIFEDLLA
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]