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The map label for this gene is citE [H]

Identifier: 182679479

GI number: 182679479

Start: 2889634

End: 2890458

Strand: Reverse

Name: citE [H]

Synonym: Bind_2534

Alternate gene names: 182679479

Gene position: 2890458-2889634 (Counterclockwise)

Preceding gene: 182679480

Following gene: 182679478

Centisome position: 69.31

GC content: 58.91

Gene sequence:

>825_bases
ATGGTGAAGCCGACACGGTCCTGGCTGTTCACGCCAGGCACTCGCCCCGATCGCTTCGCAAAGGCCGCTGAGGCTGGTGC
TGACGTTCTGATCATCGATCTCGAGGACGCAGTCGCTCAAGGCCAGAAGGCTGAGGCCCGAGCTTCAGTTCTGAGCTATT
TCGCTCATAAGCCGTCGGAGTCGATTGCACGTGCTATTCGGATCAATGGCCTCGATACGGTTCATGGTCTCGCGGACCTC
CATGCCGTCATTGAGGACGCCGTTGATGCGGATTTCCTTATCCTTCCGAAGACCGAAAGCGCCGATCACATCCTCATCTT
GGATCGTCTTCTCTCGCGAGTGGGGATCAGATCACAGCTTGTCGGTCTCATTGAGAGCGCCCGGGGGCTCACTGCCGTAG
ACAAAATCGCAGCGGCGTCTCCTCGGCTTCATGGGCTGATGCTCGGTGCAGCCGATATGGCTGCCGACCTCGGCGCAGGC
GTCAGCTGGGATAATCTTTCCTATATTCGGGGACGTTTCGTCGTGGCCTGCGCCAATGCGCGTATCGCCGCCATCGACAG
CCCGTGGTTCGACGTTCGTGATGAGGCTGGCCTTATCCAAGAAGTACGTCGAGCTGTAGGAATGGGGTTCGTCGCGAAGG
CTGCGATCCATCCTGGACAGGTTAAAGCTATCAACACGGCACTGACGCCCACCGCCGAAGAGGTTCAGCTTGCTCGCGCC
ATTCTTGTTGAAAATGAGAAGGGCGTTGGCGTCATCAATGGCAAGATGATCGACGAAGCCATCGCCCGAAAGGCGAGACG
CGTACTGGCCGCCGCGGGCGGCTGA

Upstream 100 bases:

>100_bases
TTGCAGTCATGGTCATGGGGAGGAGGGGGGCGTTTGGCCATTCCAACGACCATATCATAATGGCGCGCGACCATCGCCGT
AACCGGAAAGGAGCCGCAAC

Downstream 100 bases:

>100_bases
CCGAAGCGGGCCGGCAGCCCGCCCCACGATCGTGACCTCAAGGAGATGTTTGAATGGACAGCATATTGCCTGCCTATAAG
CTTGTCGGCGAGCGCCGCTA

Product: Citryl-CoA lyase

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MVKPTRSWLFTPGTRPDRFAKAAEAGADVLIIDLEDAVAQGQKAEARASVLSYFAHKPSESIARAIRINGLDTVHGLADL
HAVIEDAVDADFLILPKTESADHILILDRLLSRVGIRSQLVGLIESARGLTAVDKIAAASPRLHGLMLGAADMAADLGAG
VSWDNLSYIRGRFVVACANARIAAIDSPWFDVRDEAGLIQEVRRAVGMGFVAKAAIHPGQVKAINTALTPTAEEVQLARA
ILVENEKGVGVINGKMIDEAIARKARRVLAAAGG

Sequences:

>Translated_274_residues
MVKPTRSWLFTPGTRPDRFAKAAEAGADVLIIDLEDAVAQGQKAEARASVLSYFAHKPSESIARAIRINGLDTVHGLADL
HAVIEDAVDADFLILPKTESADHILILDRLLSRVGIRSQLVGLIESARGLTAVDKIAAASPRLHGLMLGAADMAADLGAG
VSWDNLSYIRGRFVVACANARIAAIDSPWFDVRDEAGLIQEVRRAVGMGFVAKAAIHPGQVKAINTALTPTAEEVQLARA
ILVENEKGVGVINGKMIDEAIARKARRVLAAAGG
>Mature_274_residues
MVKPTRSWLFTPGTRPDRFAKAAEAGADVLIIDLEDAVAQGQKAEARASVLSYFAHKPSESIARAIRINGLDTVHGLADL
HAVIEDAVDADFLILPKTESADHILILDRLLSRVGIRSQLVGLIESARGLTAVDKIAAASPRLHGLMLGAADMAADLGAG
VSWDNLSYIRGRFVVACANARIAAIDSPWFDVRDEAGLIQEVRRAVGMGFVAKAAIHPGQVKAINTALTPTAEEVQLARA
ILVENEKGVGVINGKMIDEAIARKARRVLAAAGG

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=291, Percent_Identity=26.4604810996564, Blast_Score=111, Evalue=8e-25,
Organism=Escherichia coli, GI87081764, Length=286, Percent_Identity=33.9160839160839, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17557458, Length=293, Percent_Identity=25.2559726962457, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 29019; Mature: 29019

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKPTRSWLFTPGTRPDRFAKAAEAGADVLIIDLEDAVAQGQKAEARASVLSYFAHKPSE
CCCCCCCEEECCCCCHHHHHHHHHCCCCEEEEECHHHHHCCCHHHHHHHHHHHHHCCCHH
SIARAIRINGLDTVHGLADLHAVIEDAVDADFLILPKTESADHILILDRLLSRVGIRSQL
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEHHHHHHHHHHCHHHHH
VGLIESARGLTAVDKIAAASPRLHGLMLGAADMAADLGAGVSWDNLSYIRGRFVVACANA
HHHHHHCCCCHHHHHHHHCCCCHHEEEECHHHHHHHHCCCCCCCCHHHHCCEEEEEECCC
RIAAIDSPWFDVRDEAGLIQEVRRAVGMGFVAKAAIHPGQVKAINTALTPTAEEVQLARA
EEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
ILVENEKGVGVINGKMIDEAIARKARRVLAAAGG
HHEECCCCCEEECCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKPTRSWLFTPGTRPDRFAKAAEAGADVLIIDLEDAVAQGQKAEARASVLSYFAHKPSE
CCCCCCCEEECCCCCHHHHHHHHHCCCCEEEEECHHHHHCCCHHHHHHHHHHHHHCCCHH
SIARAIRINGLDTVHGLADLHAVIEDAVDADFLILPKTESADHILILDRLLSRVGIRSQL
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEHHHHHHHHHHCHHHHH
VGLIESARGLTAVDKIAAASPRLHGLMLGAADMAADLGAGVSWDNLSYIRGRFVVACANA
HHHHHHCCCCHHHHHHHHCCCCHHEEEECHHHHHHHHCCCCCCCCHHHHCCEEEEEECCC
RIAAIDSPWFDVRDEAGLIQEVRRAVGMGFVAKAAIHPGQVKAINTALTPTAEEVQLARA
EEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
ILVENEKGVGVINGKMIDEAIARKARRVLAAAGG
HHEECCCCCEEECCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2205500; 7830578 [H]