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The map label for this gene is nuoL [H]

Identifier: 182679341

GI number: 182679341

Start: 2728080

End: 2730080

Strand: Reverse

Name: nuoL [H]

Synonym: Bind_2387

Alternate gene names: 182679341

Gene position: 2730080-2728080 (Counterclockwise)

Preceding gene: 182679342

Following gene: 182679340

Centisome position: 65.47

GC content: 57.92

Gene sequence:

>2001_bases
ATGCATGCCGCAATCGTCTTCCTCCCCCTGGCCGGCTTTCTGATTGCCGGGATTTTCGGACGCGTCATTGGCGCGCGAGC
CTCGGAAATCGTCACGACGAGCCTGTTGTTCGTCGCGGCTCTGTTGTCCTGGATCACGTTCGTGCAGGTCGGCCTTGGTG
TTGCTCCCGCGCGCACCGAGCTTCTTGCTCCCTGGTTCGACTCTGGCGCGCTTCAGGTCGATTGGGCCTTGCGCATCGAC
ACGCTGACGGCGGTCATGCTCGTCGTCGTCACGACGGTTTCGGCGCTCGTGCATCTCTATTCGATCGGCTATATGCACGA
GGATCCCTCACGGTCGCGCTTCTTTGCCTATCTCTCCTTCTTCACCTTCACCATGTTGACCTTGGTGACGGCGGATAATC
TGGTGCAGATGTTCTTCGGCTGGGAAGGTGTCGGTCTTGCGTCCTATCTTCTGATCGGCTTCTGGTACGAAAAGCCTTCC
GCTTGCGCCGCCGCCATCAAGGCTTTCGTCGCCAACCGCGTCGGCGACTTTGGCTTTCTGCTTGGAATTTTCCTGGTCTT
CCTCCTCACCCATTCGGTGAGCTTCGATCAGGTCTTCGCCGCGGCTCCCAGCCTTGCCGGCAAGAGCTTGCATGTCTTCG
GACATGATTTCGATGCCATGACCATCACATGCCTGTTGTTATTCATGGGCGCGATGGGTAAATCCGCGCAATTCCTGCTG
CATACGTGGTTGCCCGACGCGATGGAGGGACCGACCCCGGTTTCCGCTCTGATCCATGCGGCGACAATGGTGACCGCCGG
CGTCTTCATGGTTGCTCGCCTCTCACCCTTGTTCGAGCAGGCTCCTGTCGCTCTTTCCTTCGTCACGATCATCGGTGCGA
CGACGGCTTTCTTCGCCGCCACTGTCGGCCTTGTGCAAAACGATATCAAACGCGTCATCGCTTATTCGACCTGCTCGCAG
CTCGGCTATATGTTCGTGGCGCTCGGCGTTGGTGGTTATTCACTGGGTATCTTCCACCTATTCACCCACGCCTTCTTCAA
GGCCCTTCTGTTCCTTGGCGCCGGCTCGGTGATCCATGCCATGCATCATGAGCAGGACATGCGGAAGATGGGCGCGCTGC
GGGACCGCATTCCCTTCACCTTCTGGATGATGACGCTCGGCACGCTGGCGCTGACCGGATTTCCGCTGACAGCCGGTTAT
TTTTCCAAGGATGCGATTATCGAGGCGGCCTTCGCTTCTGAGCGCACGGGCGCCCTCTATGGTTATGTCGCGACGGTCGT
CGCCGCTGGCCTTACATCCTTCTATTCCTGGCGCCTGGTGTTCATGACCTTCTTTGGTCCGGCTCACTGGGGCGCGGATG
CCCATGCGGCCCATGATGATCACGGGCATGCCCATGCCTCCGGACACGACGATCATGGCCATGCCCATGCGCTCGAACCG
CATGAGCCGCCCTTCGTCATGCGTCTGCCTTTGCTGATCCTTGGCGCCGGCGCCGTGTTCGCGGGTCTCTTGTTCGATCA
TTCCTTCATCGGGGAAGGCCAGGAAGGCTTCTGGAAAGAGGCTCTGTTCTATGGACCAAACAACCATATTTTCCATCAAA
TGGAGGAAATTCCGCGTCTTGCCGGTCTTGCACCGACCTTCATGATGGCTCTTGGTTTTCTGGTCTCGCTTTATGTTTAT
ATCCTGAGACCGGGCACAGCCCAGCGCTGGGCGCAGACCAATCCGCTCGTCTACAATTTCCTGCTGAACAAATGGTATTT
CGATGAACTTTATGACCTCATTCTGATCCGTCCCGCCTTTTGGCTCGGCCGGCTGTTCTGGAAGAGGGGCGATCAAGGGT
TCATCGATCGTTTCGGACCGGACGGGGTTTCTGCTGTCGTGATCGATGTCACCCGGCGCGTCGTGAAATTGCAGACCGGT
TACATCTACCATTACGCATTCGCCATGCTCATCGGTGTCGCCGCGATCGTCACCTTCTATGTCGTCGGAGGTGTGCACTA
A

Upstream 100 bases:

>100_bases
GCGGAGGCGGCTATCGGCCTCGCCATTCTCGTTACTTTCTATCGCAATCGCGGTTCCATCGCGGTCGAAGACATTCATAT
GATGAAGGGTTGAGCCGGTT

Downstream 100 bases:

>100_bases
TGTTCGGCTTCGGTATTCTTTCAGCCCTCATTTTCCTGCCCCTCGTCGGCGCGCTCTTCATCGCGTTGCTGCCGGGAGAC
AGTGAAGCCAGCCGTTCCAG

Product: proton-translocating NADH-quinone oxidoreductase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MHAAIVFLPLAGFLIAGIFGRVIGARASEIVTTSLLFVAALLSWITFVQVGLGVAPARTELLAPWFDSGALQVDWALRID
TLTAVMLVVVTTVSALVHLYSIGYMHEDPSRSRFFAYLSFFTFTMLTLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPS
ACAAAIKAFVANRVGDFGFLLGIFLVFLLTHSVSFDQVFAAAPSLAGKSLHVFGHDFDAMTITCLLLFMGAMGKSAQFLL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARLSPLFEQAPVALSFVTIIGATTAFFAATVGLVQNDIKRVIAYSTCSQ
LGYMFVALGVGGYSLGIFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRKMGALRDRIPFTFWMMTLGTLALTGFPLTAGY
FSKDAIIEAAFASERTGALYGYVATVVAAGLTSFYSWRLVFMTFFGPAHWGADAHAAHDDHGHAHASGHDDHGHAHALEP
HEPPFVMRLPLLILGAGAVFAGLLFDHSFIGEGQEGFWKEALFYGPNNHIFHQMEEIPRLAGLAPTFMMALGFLVSLYVY
ILRPGTAQRWAQTNPLVYNFLLNKWYFDELYDLILIRPAFWLGRLFWKRGDQGFIDRFGPDGVSAVVIDVTRRVVKLQTG
YIYHYAFAMLIGVAAIVTFYVVGGVH

Sequences:

>Translated_666_residues
MHAAIVFLPLAGFLIAGIFGRVIGARASEIVTTSLLFVAALLSWITFVQVGLGVAPARTELLAPWFDSGALQVDWALRID
TLTAVMLVVVTTVSALVHLYSIGYMHEDPSRSRFFAYLSFFTFTMLTLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPS
ACAAAIKAFVANRVGDFGFLLGIFLVFLLTHSVSFDQVFAAAPSLAGKSLHVFGHDFDAMTITCLLLFMGAMGKSAQFLL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARLSPLFEQAPVALSFVTIIGATTAFFAATVGLVQNDIKRVIAYSTCSQ
LGYMFVALGVGGYSLGIFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRKMGALRDRIPFTFWMMTLGTLALTGFPLTAGY
FSKDAIIEAAFASERTGALYGYVATVVAAGLTSFYSWRLVFMTFFGPAHWGADAHAAHDDHGHAHASGHDDHGHAHALEP
HEPPFVMRLPLLILGAGAVFAGLLFDHSFIGEGQEGFWKEALFYGPNNHIFHQMEEIPRLAGLAPTFMMALGFLVSLYVY
ILRPGTAQRWAQTNPLVYNFLLNKWYFDELYDLILIRPAFWLGRLFWKRGDQGFIDRFGPDGVSAVVIDVTRRVVKLQTG
YIYHYAFAMLIGVAAIVTFYVVGGVH
>Mature_666_residues
MHAAIVFLPLAGFLIAGIFGRVIGARASEIVTTSLLFVAALLSWITFVQVGLGVAPARTELLAPWFDSGALQVDWALRID
TLTAVMLVVVTTVSALVHLYSIGYMHEDPSRSRFFAYLSFFTFTMLTLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPS
ACAAAIKAFVANRVGDFGFLLGIFLVFLLTHSVSFDQVFAAAPSLAGKSLHVFGHDFDAMTITCLLLFMGAMGKSAQFLL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARLSPLFEQAPVALSFVTIIGATTAFFAATVGLVQNDIKRVIAYSTCSQ
LGYMFVALGVGGYSLGIFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRKMGALRDRIPFTFWMMTLGTLALTGFPLTAGY
FSKDAIIEAAFASERTGALYGYVATVVAAGLTSFYSWRLVFMTFFGPAHWGADAHAAHDDHGHAHASGHDDHGHAHALEP
HEPPFVMRLPLLILGAGAVFAGLLFDHSFIGEGQEGFWKEALFYGPNNHIFHQMEEIPRLAGLAPTFMMALGFLVSLYVY
ILRPGTAQRWAQTNPLVYNFLLNKWYFDELYDLILIRPAFWLGRLFWKRGDQGFIDRFGPDGVSAVVIDVTRRVVKLQTG
YIYHYAFAMLIGVAAIVTFYVVGGVH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=448, Percent_Identity=39.0625, Blast_Score=310, Evalue=4e-84,
Organism=Escherichia coli, GI1788614, Length=605, Percent_Identity=39.1735537190083, Blast_Score=352, Evalue=5e-98,
Organism=Escherichia coli, GI1788829, Length=350, Percent_Identity=32.8571428571429, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788827, Length=460, Percent_Identity=29.5652173913043, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788831, Length=356, Percent_Identity=32.3033707865169, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI145693160, Length=438, Percent_Identity=24.2009132420091, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788613, Length=374, Percent_Identity=24.0641711229947, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI2367154, Length=143, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 73057; Mature: 73057

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAAIVFLPLAGFLIAGIFGRVIGARASEIVTTSLLFVAALLSWITFVQVGLGVAPARTE
CCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LLAPWFDSGALQVDWALRIDTLTAVMLVVVTTVSALVHLYSIGYMHEDPSRSRFFAYLSF
HHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FTFTMLTLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPSACAAAIKAFVANRVGDFGFL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHH
LGIFLVFLLTHSVSFDQVFAAAPSLAGKSLHVFGHDFDAMTITCLLLFMGAMGKSAQFLL
HHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHH
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARLSPLFEQAPVALSFVTIIGATTAFFAA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TVGLVQNDIKRVIAYSTCSQLGYMFVALGVGGYSLGIFHLFTHAFFKALLFLGAGSVIHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
MHHEQDMRKMGALRDRIPFTFWMMTLGTLALTGFPLTAGYFSKDAIIEAAFASERTGALY
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHH
GYVATVVAAGLTSFYSWRLVFMTFFGPAHWGADAHAAHDDHGHAHASGHDDHGHAHALEP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HEPPFVMRLPLLILGAGAVFAGLLFDHSFIGEGQEGFWKEALFYGPNNHIFHQMEEIPRL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEECCCCHHHHHHHHHHHH
AGLAPTFMMALGFLVSLYVYILRPGTAQRWAQTNPLVYNFLLNKWYFDELYDLILIRPAF
HCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLGRLFWKRGDQGFIDRFGPDGVSAVVIDVTRRVVKLQTGYIYHYAFAMLIGVAAIVTFY
HHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VVGGVH
HHCCCC
>Mature Secondary Structure
MHAAIVFLPLAGFLIAGIFGRVIGARASEIVTTSLLFVAALLSWITFVQVGLGVAPARTE
CCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LLAPWFDSGALQVDWALRIDTLTAVMLVVVTTVSALVHLYSIGYMHEDPSRSRFFAYLSF
HHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FTFTMLTLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPSACAAAIKAFVANRVGDFGFL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHH
LGIFLVFLLTHSVSFDQVFAAAPSLAGKSLHVFGHDFDAMTITCLLLFMGAMGKSAQFLL
HHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHH
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARLSPLFEQAPVALSFVTIIGATTAFFAA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TVGLVQNDIKRVIAYSTCSQLGYMFVALGVGGYSLGIFHLFTHAFFKALLFLGAGSVIHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
MHHEQDMRKMGALRDRIPFTFWMMTLGTLALTGFPLTAGYFSKDAIIEAAFASERTGALY
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHH
GYVATVVAAGLTSFYSWRLVFMTFFGPAHWGADAHAAHDDHGHAHASGHDDHGHAHALEP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HEPPFVMRLPLLILGAGAVFAGLLFDHSFIGEGQEGFWKEALFYGPNNHIFHQMEEIPRL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEECCCCHHHHHHHHHHHH
AGLAPTFMMALGFLVSLYVYILRPGTAQRWAQTNPLVYNFLLNKWYFDELYDLILIRPAF
HCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLGRLFWKRGDQGFIDRFGPDGVSAVVIDVTRRVVKLQTGYIYHYAFAMLIGVAAIVTFY
HHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VVGGVH
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]