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The map label for this gene is fabD [H]

Identifier: 182679256

GI number: 182679256

Start: 2632185

End: 2633159

Strand: Reverse

Name: fabD [H]

Synonym: Bind_2300

Alternate gene names: 182679256

Gene position: 2633159-2632185 (Counterclockwise)

Preceding gene: 182679258

Following gene: 182679255

Centisome position: 63.14

GC content: 63.69

Gene sequence:

>975_bases
ATGGGCCAAGCCATGTCCAAGGCATTTGTTTTTCCCGGCCAAGGATCACAAGCGGTCGGCATGGGCAAGGCTCTTTATGA
GAGCTTCGCACCGGCTCGCGCGGTCTTCGACGAAGTCGACGAGGCTTTGGGAGAGAGATTATCGACCCTGATATTCGAGG
GGCCGGAAGCGGATTTGACTCTGACCGCCAACGCGCAGCCCGCCTTGATGGCGGTAAGTCTCGCTGTGGTGCGCGTGCTC
GAGGCGGAGGCAGATCTCGATCTCGCCCGCGACGCCACCTATGTCGCCGGTCATTCGCTCGGTGAATATTCGGCGCTCGC
GGCGGCGGGATCCTTGACGCTTGCCACAACCGCCCGCTTGCTGCGGCAGCGCGGCGCGGCCATGCAAAGCGCCGTACCGG
TCGGGGTCGGTGCCATGGCGGCTTTGCTCGGCCTCGATTATGAGACTGGTCTCGCCGTGACGAAACAGGCGGAGGCGGAG
ACCGGCGAAAATGCGGTCTGTGCGATTGCCAATGACAATGGGGGTGGCCAGGTCGTCGCCTCCGGGTCGAAGGCGGCGGT
CATGCGGGCCATGGAAATCGCCAAGGAGAAAGGCGCCAAGCGCTCGATGCTCCTGCCAGTTTCGGCGCCTTTCCATTGTC
CCTTGATGGCGCCGGCGGCGGCGGTCATGGCCGAGGCCCTGGCGGAGGTGTCTATTCGTCCGCCTTGTGTGCCGCTGGTC
GCTAATGTCATTGCCGCGCCGGTGACGGATCCGGAAAAGATCCGATCCCTGCTCGTGAGCCAGGTGACCGGGACGGTGCG
TTGGCGTGAAAGCGTGGCCTTCATGGCGGCTGAAGGGGTCGATCTCTTCATCGAATGTGGCTCTGGCAAGGTCCTCACGG
GTCTGTTGAAGCGGATCGCGCCGCAGGCCCGGGGTCTGACGATCGGCCAACCCGCCGATCTTGAGGCTTTGCGGGCCGAG
AGCGAAAAAGTTTGA

Upstream 100 bases:

>100_bases
CAAAAGATGGAGGCATGCTTTCCGTGGCAGGAATGCGCACCCTTGCCGCTTGACTTCACGGGCAGGGAATGCCACTCGCT
CCCGCTCCAATTGGAGGGAG

Downstream 100 bases:

>100_bases
GGCGCTTATAAAGGCTCACCGAGAGCCTGTGGTATCGCCTTGTCGTATCTTCTCCCTCCTGGAGCCATTCATTCATGTTC
GATCTGACCGGCAAGACAGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MGQAMSKAFVFPGQGSQAVGMGKALYESFAPARAVFDEVDEALGERLSTLIFEGPEADLTLTANAQPALMAVSLAVVRVL
EAEADLDLARDATYVAGHSLGEYSALAAAGSLTLATTARLLRQRGAAMQSAVPVGVGAMAALLGLDYETGLAVTKQAEAE
TGENAVCAIANDNGGGQVVASGSKAAVMRAMEIAKEKGAKRSMLLPVSAPFHCPLMAPAAAVMAEALAEVSIRPPCVPLV
ANVIAAPVTDPEKIRSLLVSQVTGTVRWRESVAFMAAEGVDLFIECGSGKVLTGLLKRIAPQARGLTIGQPADLEALRAE
SEKV

Sequences:

>Translated_324_residues
MGQAMSKAFVFPGQGSQAVGMGKALYESFAPARAVFDEVDEALGERLSTLIFEGPEADLTLTANAQPALMAVSLAVVRVL
EAEADLDLARDATYVAGHSLGEYSALAAAGSLTLATTARLLRQRGAAMQSAVPVGVGAMAALLGLDYETGLAVTKQAEAE
TGENAVCAIANDNGGGQVVASGSKAAVMRAMEIAKEKGAKRSMLLPVSAPFHCPLMAPAAAVMAEALAEVSIRPPCVPLV
ANVIAAPVTDPEKIRSLLVSQVTGTVRWRESVAFMAAEGVDLFIECGSGKVLTGLLKRIAPQARGLTIGQPADLEALRAE
SEKV
>Mature_323_residues
GQAMSKAFVFPGQGSQAVGMGKALYESFAPARAVFDEVDEALGERLSTLIFEGPEADLTLTANAQPALMAVSLAVVRVLE
AEADLDLARDATYVAGHSLGEYSALAAAGSLTLATTARLLRQRGAAMQSAVPVGVGAMAALLGLDYETGLAVTKQAEAET
GENAVCAIANDNGGGQVVASGSKAAVMRAMEIAKEKGAKRSMLLPVSAPFHCPLMAPAAAVMAEALAEVSIRPPCVPLVA
NVIAAPVTDPEKIRSLLVSQVTGTVRWRESVAFMAAEGVDLFIECGSGKVLTGLLKRIAPQARGLTIGQPADLEALRAES
EKV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=30.5921052631579, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=44.336569579288, Blast_Score=210, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI71984332, Length=298, Percent_Identity=30.2013422818792, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=325, Percent_Identity=27.6923076923077, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24665753, Length=302, Percent_Identity=34.4370860927152, Blast_Score=131, Evalue=8e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33331; Mature: 33200

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQAMSKAFVFPGQGSQAVGMGKALYESFAPARAVFDEVDEALGERLSTLIFEGPEADLT
CCCCCCCEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LTANAQPALMAVSLAVVRVLEAEADLDLARDATYVAGHSLGEYSALAAAGSLTLATTARL
EECCCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCCCCHHHHHHHCCCHHHHHHHHH
LRQRGAAMQSAVPVGVGAMAALLGLDYETGLAVTKQAEAETGENAVCAIANDNGGGQVVA
HHHHCHHHHHCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCEEEE
SGSKAAVMRAMEIAKEKGAKRSMLLPVSAPFHCPLMAPAAAVMAEALAEVSIRPPCVPLV
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
ANVIAAPVTDPEKIRSLLVSQVTGTVRWRESVAFMAAEGVDLFIECGSGKVLTGLLKRIA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHHC
PQARGLTIGQPADLEALRAESEKV
HHHCCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
GQAMSKAFVFPGQGSQAVGMGKALYESFAPARAVFDEVDEALGERLSTLIFEGPEADLT
CCCCCCEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LTANAQPALMAVSLAVVRVLEAEADLDLARDATYVAGHSLGEYSALAAAGSLTLATTARL
EECCCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCCCCHHHHHHHCCCHHHHHHHHH
LRQRGAAMQSAVPVGVGAMAALLGLDYETGLAVTKQAEAETGENAVCAIANDNGGGQVVA
HHHHCHHHHHCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCEEEE
SGSKAAVMRAMEIAKEKGAKRSMLLPVSAPFHCPLMAPAAAVMAEALAEVSIRPPCVPLV
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
ANVIAAPVTDPEKIRSLLVSQVTGTVRWRESVAFMAAEGVDLFIECGSGKVLTGLLKRIA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHHC
PQARGLTIGQPADLEALRAESEKV
HHHCCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]