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The map label for this gene is atsA [H]

Identifier: 182679168

GI number: 182679168

Start: 2529247

End: 2531775

Strand: Direct

Name: atsA [H]

Synonym: Bind_2206

Alternate gene names: 182679168

Gene position: 2529247-2531775 (Clockwise)

Preceding gene: 182679166

Following gene: 182679169

Centisome position: 60.65

GC content: 52.95

Gene sequence:

>2529_bases
ATGCGCGGAGTGACACGGAGCAAAGTGCGAACGAGCCTATCAGCGATCTTTCTTACGCTGACGCTCATATCGGTGGTGCC
TGCGGCCGCTCAACAGCGAGAAGGCGTACCCGGCTCCCCAAGTGCAACAACGACGATCGATGGGCGATATTTGCCACCCC
CTCCACCGCCATTTGGCGGTGAAATTAATTTAAACGCCGTGCAATCAAAACCTTATTGGCCAGCGCGCGTTGTGCCCCCG
AAGGGAGCCCCGAATGTCTTGCTGATTATGACCGATGACGTCGGTTTTGGCGCTCCGAGCACTTTTGGAGGGGTCATTCC
CACTCCGGCTCTCGACCGCATTGCCAATGCTGGCTTGCGTTATACGCAATTTCACTCGACAGCCCTCTGCTCACCAACAC
GCGCCGCGCTTATTACCGGGCGCAACCATCATTCGGTGGGTTTCGGCCAAATTTCAGAAATGTCCACAGGTTTCCCCGGT
TATGACAGTATCATCACCAGAGATACAGCGACGATCGGTCGAATTCTGAAAGACAATGGCTACGCGACCTCGTGGTTCGG
CAAGAACCATAACACTCCAGCCTTTCAGGCGAGCCAAGCGGGACCTTTCGAGCAATGGCCCATCGGTATGGGCTTTGAAT
ATTTCTACGGGTTTGTTGGTGGTGATACCAGCCAGTGGCAGCCAAATCTGTTCCGCCAAACCACGGCAATCTATCCCTAT
ATCGGTCATCCCGACTGGAACCTGACCACGGCCATGGCCGATGATGCCATCGCTCATATCAAAATGCTGAACGAAGTCGA
TCCCACTAAACCATTCTTTGTTAATTATACCCCCGGGGGCACCCACGCACCACACCACCCGACGCCCGAATGGATCAAAA
AGATCAGTGACATGCATCTATTCGACAAGGGCTGGAACACACTCCGCGAGACGATTTTCTCTAACCAAAAGCGGCTCAAT
GTTATCCCACAAGATGCCAAGCTTACGCCCTGGCCTGATGATTTGCTGAAGCAATGGGATACACTTACAGAGGACGAGAA
AAAGCTGTTCATTCGTCAAGCCGACGTCTACGCCGCTTATCTTACCTATACCGACCATGAGATCGGCCGGGTGATTCAAG
CGGTCGAGGATACCGGCAAGCTCGACAATACATTGATTATTTACATCAGCGGCGACAATGGTTCCAGTGCGGAGGGATCA
CCCAATGGCACACCTAATGAAGTCGCGCAATTCAACAGCGTCGAGGTGCCGGTAGCAGAACAGCTAAAGTATTTCTACGA
CGTCTGGGGTTCGGACAAAACTTATAATCACATGGCAGTGGGTTGGACCTGGGCTTTCGACACGCCCTATAAATGGACGA
AACAAGTGGCATCGCATTTCGGCGGCACACGGCAAGGCATGGCCATCAGTTGGCCGGGCCACATTAAAGATGTCGGAGGC
ATCCGTAATCAGTTTCATCACGTCATCGATATTGTCCCGACCGTTTTGGAAGCAGCGAATATCTCGCCTCCGGTGATGGT
CGATGGCATCGCCCAAAATCCGATCGAAGGCGTGAGCTTAGCCTATACTTTCGATAAAGCGAACGCCGACACCCCCACCA
AGCATCACACCCAATATTTCGAGATGTTCGGTAATCGCGGCATCTATCACGATGGCTGGTACGCCAATACACAACCGATC
AGCCCGCCGTGGAAACTCGGCGCCACACCAAACCCAAACGTCATAAACAGCTATAAATGGGAGCTTTACGATCTCACCAA
GGATTGGACGCAGAACGAAGATCTCGCCGCCGCCAATCCCGCCAAGCTGAAAGAGATGCAGGATCTTTTCCTGGTCGAAG
CCGCCAAATATCAGGTCTTCCCGCTCGACAATTCACTCGCTTCACGAATGGTCGTGCCGAGGCCCAGCGTTACGGCCGGA
AGAACTGAATTCACTTATACAGGCGAATTGACCGGCGTCCCGATGGGCGATGCTCCAAGTTTGATTGCGGCTTCCTATAC
GATCACAGCAGAGATCGATGTCCCTGAAGGTGGCGCCGAGGGAATACTCGCGACCCAAGGAGGACGCTTCGGCGGATGGG
GGTTCTATCTTGTGAAAGGCAAACCCGTCTTTACCTGGAACCTGCTCGATCTCAAACGCGTTCGTTGGGAAAATCCGGAA
GCCCTTTTACCAGGAAAACATGCTCTGGTCTTCGACTTCAAATATGACGGCCTCGGTTTTGGGACGTTGGCCTTCAACAA
TGTGAGCGGCCTTGGCCAGGGGGGCACGGGCACGCTCCGGGTCGATGGGAAAATCGTGGCCACACAAACGATGGAACGAA
CGATTCCGGTTATTCTTCAATGGGATGAGACCTTTGACATTGGGGCCGATACCGGTACGCCTGTTGATGATAATGACTAT
CAAGTACCGTTCGGATTTACTGGTAAACTCAACAAACTGACGATCAAGATCGATCGACCGAAATTATCGCCAGAAGACGA
GAAACGTCTCATGCAAGAAGGACAACGCAGCAATCGCATGAGCGAATAG

Upstream 100 bases:

>100_bases
TGCGCTCCCTATGTTCCGTGTTAGTCTGATTACACACTGCCGCTATTGATCAGCATCAATGATCCGAAGCACCTGAATGA
TGACCCTCAGGAGTGAACAT

Downstream 100 bases:

>100_bases
TTTACACTCAAGCAATGTCTAGTCAGCATTCAGAACGAGGAGACAAATATGACGAAGAGCGTGCAAAAACTCGCCGGCAT
GGCACTGGGAGCAGTCCTGA

Product: sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 842; Mature: 842

Protein sequence:

>842_residues
MRGVTRSKVRTSLSAIFLTLTLISVVPAAAQQREGVPGSPSATTTIDGRYLPPPPPPFGGEINLNAVQSKPYWPARVVPP
KGAPNVLLIMTDDVGFGAPSTFGGVIPTPALDRIANAGLRYTQFHSTALCSPTRAALITGRNHHSVGFGQISEMSTGFPG
YDSIITRDTATIGRILKDNGYATSWFGKNHNTPAFQASQAGPFEQWPIGMGFEYFYGFVGGDTSQWQPNLFRQTTAIYPY
IGHPDWNLTTAMADDAIAHIKMLNEVDPTKPFFVNYTPGGTHAPHHPTPEWIKKISDMHLFDKGWNTLRETIFSNQKRLN
VIPQDAKLTPWPDDLLKQWDTLTEDEKKLFIRQADVYAAYLTYTDHEIGRVIQAVEDTGKLDNTLIIYISGDNGSSAEGS
PNGTPNEVAQFNSVEVPVAEQLKYFYDVWGSDKTYNHMAVGWTWAFDTPYKWTKQVASHFGGTRQGMAISWPGHIKDVGG
IRNQFHHVIDIVPTVLEAANISPPVMVDGIAQNPIEGVSLAYTFDKANADTPTKHHTQYFEMFGNRGIYHDGWYANTQPI
SPPWKLGATPNPNVINSYKWELYDLTKDWTQNEDLAAANPAKLKEMQDLFLVEAAKYQVFPLDNSLASRMVVPRPSVTAG
RTEFTYTGELTGVPMGDAPSLIAASYTITAEIDVPEGGAEGILATQGGRFGGWGFYLVKGKPVFTWNLLDLKRVRWENPE
ALLPGKHALVFDFKYDGLGFGTLAFNNVSGLGQGGTGTLRVDGKIVATQTMERTIPVILQWDETFDIGADTGTPVDDNDY
QVPFGFTGKLNKLTIKIDRPKLSPEDEKRLMQEGQRSNRMSE

Sequences:

>Translated_842_residues
MRGVTRSKVRTSLSAIFLTLTLISVVPAAAQQREGVPGSPSATTTIDGRYLPPPPPPFGGEINLNAVQSKPYWPARVVPP
KGAPNVLLIMTDDVGFGAPSTFGGVIPTPALDRIANAGLRYTQFHSTALCSPTRAALITGRNHHSVGFGQISEMSTGFPG
YDSIITRDTATIGRILKDNGYATSWFGKNHNTPAFQASQAGPFEQWPIGMGFEYFYGFVGGDTSQWQPNLFRQTTAIYPY
IGHPDWNLTTAMADDAIAHIKMLNEVDPTKPFFVNYTPGGTHAPHHPTPEWIKKISDMHLFDKGWNTLRETIFSNQKRLN
VIPQDAKLTPWPDDLLKQWDTLTEDEKKLFIRQADVYAAYLTYTDHEIGRVIQAVEDTGKLDNTLIIYISGDNGSSAEGS
PNGTPNEVAQFNSVEVPVAEQLKYFYDVWGSDKTYNHMAVGWTWAFDTPYKWTKQVASHFGGTRQGMAISWPGHIKDVGG
IRNQFHHVIDIVPTVLEAANISPPVMVDGIAQNPIEGVSLAYTFDKANADTPTKHHTQYFEMFGNRGIYHDGWYANTQPI
SPPWKLGATPNPNVINSYKWELYDLTKDWTQNEDLAAANPAKLKEMQDLFLVEAAKYQVFPLDNSLASRMVVPRPSVTAG
RTEFTYTGELTGVPMGDAPSLIAASYTITAEIDVPEGGAEGILATQGGRFGGWGFYLVKGKPVFTWNLLDLKRVRWENPE
ALLPGKHALVFDFKYDGLGFGTLAFNNVSGLGQGGTGTLRVDGKIVATQTMERTIPVILQWDETFDIGADTGTPVDDNDY
QVPFGFTGKLNKLTIKIDRPKLSPEDEKRLMQEGQRSNRMSE
>Mature_842_residues
MRGVTRSKVRTSLSAIFLTLTLISVVPAAAQQREGVPGSPSATTTIDGRYLPPPPPPFGGEINLNAVQSKPYWPARVVPP
KGAPNVLLIMTDDVGFGAPSTFGGVIPTPALDRIANAGLRYTQFHSTALCSPTRAALITGRNHHSVGFGQISEMSTGFPG
YDSIITRDTATIGRILKDNGYATSWFGKNHNTPAFQASQAGPFEQWPIGMGFEYFYGFVGGDTSQWQPNLFRQTTAIYPY
IGHPDWNLTTAMADDAIAHIKMLNEVDPTKPFFVNYTPGGTHAPHHPTPEWIKKISDMHLFDKGWNTLRETIFSNQKRLN
VIPQDAKLTPWPDDLLKQWDTLTEDEKKLFIRQADVYAAYLTYTDHEIGRVIQAVEDTGKLDNTLIIYISGDNGSSAEGS
PNGTPNEVAQFNSVEVPVAEQLKYFYDVWGSDKTYNHMAVGWTWAFDTPYKWTKQVASHFGGTRQGMAISWPGHIKDVGG
IRNQFHHVIDIVPTVLEAANISPPVMVDGIAQNPIEGVSLAYTFDKANADTPTKHHTQYFEMFGNRGIYHDGWYANTQPI
SPPWKLGATPNPNVINSYKWELYDLTKDWTQNEDLAAANPAKLKEMQDLFLVEAAKYQVFPLDNSLASRMVVPRPSVTAG
RTEFTYTGELTGVPMGDAPSLIAASYTITAEIDVPEGGAEGILATQGGRFGGWGFYLVKGKPVFTWNLLDLKRVRWENPE
ALLPGKHALVFDFKYDGLGFGTLAFNNVSGLGQGGTGTLRVDGKIVATQTMERTIPVILQWDETFDIGADTGTPVDDNDY
QVPFGFTGKLNKLTIKIDRPKLSPEDEKRLMQEGQRSNRMSE

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI53831991, Length=150, Percent_Identity=36, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI157266309, Length=152, Percent_Identity=35.5263157894737, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI71852586, Length=157, Percent_Identity=35.6687898089172, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI71852584, Length=360, Percent_Identity=27.2222222222222, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI58743319, Length=175, Percent_Identity=31.4285714285714, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI31742482, Length=140, Percent_Identity=33.5714285714286, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI109389362, Length=330, Percent_Identity=23.030303030303, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI4503899, Length=227, Percent_Identity=29.5154185022026, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1790233, Length=326, Percent_Identity=26.6871165644172, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281366397, Length=452, Percent_Identity=20.1327433628319, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281366395, Length=452, Percent_Identity=20.1327433628319, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24666163, Length=452, Percent_Identity=20.1327433628319, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 92966; Mature: 92966

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGVTRSKVRTSLSAIFLTLTLISVVPAAAQQREGVPGSPSATTTIDGRYLPPPPPPFGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEECCCCCCCCCC
EINLNAVQSKPYWPARVVPPKGAPNVLLIMTDDVGFGAPSTFGGVIPTPALDRIANAGLR
EEEEEEECCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCE
YTQFHSTALCSPTRAALITGRNHHSVGFGQISEMSTGFPGYDSIITRDTATIGRILKDNG
EEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCCCHHEECCHHHHHHHHHCCC
YATSWFGKNHNTPAFQASQAGPFEQWPIGMGFEYFYGFVGGDTSQWQPNLFRQTTAIYPY
CEEEECCCCCCCCCEECCCCCCCCCCCCCCCHHHHHEEECCCCCCCCCHHHHHHHEEEEE
IGHPDWNLTTAMADDAIAHIKMLNEVDPTKPFFVNYTPGGTHAPHHPTPEWIKKISDMHL
CCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
FDKGWNTLRETIFSNQKRLNVIPQDAKLTPWPDDLLKQWDTLTEDEKKLFIRQADVYAAY
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHEEEEECCEEEEE
LTYTDHEIGRVIQAVEDTGKLDNTLIIYISGDNGSSAEGSPNGTPNEVAQFNSVEVPVAE
EEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCHHH
QLKYFYDVWGSDKTYNHMAVGWTWAFDTPYKWTKQVASHFGGTRQGMAISWPGHIKDVGG
HHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHH
IRNQFHHVIDIVPTVLEAANISPPVMVDGIAQNPIEGVSLAYTFDKANADTPTKHHTQYF
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHH
EMFGNRGIYHDGWYANTQPISPPWKLGATPNPNVINSYKWELYDLTKDWTQNEDLAAANP
HHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
AKLKEMQDLFLVEAAKYQVFPLDNSLASRMVVPRPSVTAGRTEFTYTGELTGVPMGDAPS
HHHHHHHHHHHEEECCEEEEECCCHHHHCEECCCCCCCCCCEEEEEECEEECCCCCCCCC
LIAASYTITAEIDVPEGGAEGILATQGGRFGGWGFYLVKGKPVFTWNLLDLKRVRWENPE
EEEEEEEEEEEEECCCCCCCCEEEECCCCCCCEEEEEEECCEEEEEEHHHHHHHCCCCCC
ALLPGKHALVFDFKYDGLGFGTLAFNNVSGLGQGGTGTLRVDGKIVATQTMERTIPVILQ
EECCCCEEEEEEEEECCCEEEEEEECCCCCCCCCCCEEEEECCEEEEECHHCCCCCEEEE
WDETFDIGADTGTPVDDNDYQVPFGFTGKLNKLTIKIDRPKLSPEDEKRLMQEGQRSNRM
ECCCEECCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCC
SE
CC
>Mature Secondary Structure
MRGVTRSKVRTSLSAIFLTLTLISVVPAAAQQREGVPGSPSATTTIDGRYLPPPPPPFGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEECCCCCCCCCC
EINLNAVQSKPYWPARVVPPKGAPNVLLIMTDDVGFGAPSTFGGVIPTPALDRIANAGLR
EEEEEEECCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCE
YTQFHSTALCSPTRAALITGRNHHSVGFGQISEMSTGFPGYDSIITRDTATIGRILKDNG
EEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCCCHHEECCHHHHHHHHHCCC
YATSWFGKNHNTPAFQASQAGPFEQWPIGMGFEYFYGFVGGDTSQWQPNLFRQTTAIYPY
CEEEECCCCCCCCCEECCCCCCCCCCCCCCCHHHHHEEECCCCCCCCCHHHHHHHEEEEE
IGHPDWNLTTAMADDAIAHIKMLNEVDPTKPFFVNYTPGGTHAPHHPTPEWIKKISDMHL
CCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
FDKGWNTLRETIFSNQKRLNVIPQDAKLTPWPDDLLKQWDTLTEDEKKLFIRQADVYAAY
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHEEEEECCEEEEE
LTYTDHEIGRVIQAVEDTGKLDNTLIIYISGDNGSSAEGSPNGTPNEVAQFNSVEVPVAE
EEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCHHH
QLKYFYDVWGSDKTYNHMAVGWTWAFDTPYKWTKQVASHFGGTRQGMAISWPGHIKDVGG
HHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHH
IRNQFHHVIDIVPTVLEAANISPPVMVDGIAQNPIEGVSLAYTFDKANADTPTKHHTQYF
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHH
EMFGNRGIYHDGWYANTQPISPPWKLGATPNPNVINSYKWELYDLTKDWTQNEDLAAANP
HHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
AKLKEMQDLFLVEAAKYQVFPLDNSLASRMVVPRPSVTAGRTEFTYTGELTGVPMGDAPS
HHHHHHHHHHHEEECCEEEEECCCHHHHCEECCCCCCCCCCEEEEEECEEECCCCCCCCC
LIAASYTITAEIDVPEGGAEGILATQGGRFGGWGFYLVKGKPVFTWNLLDLKRVRWENPE
EEEEEEEEEEEEECCCCCCCCEEEECCCCCCCEEEEEEECCEEEEEEHHHHHHHCCCCCC
ALLPGKHALVFDFKYDGLGFGTLAFNNVSGLGQGGTGTLRVDGKIVATQTMERTIPVILQ
EECCCCEEEEEEEEECCCEEEEEEECCCCCCCCCCCEEEEECCEEEEECHHCCCCCEEEE
WDETFDIGADTGTPVDDNDYQVPFGFTGKLNKLTIKIDRPKLSPEDEKRLMQEGQRSNRM
ECCCEECCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCC
SE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]