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The map label for this gene is qseC [H]

Identifier: 182679118

GI number: 182679118

Start: 2462014

End: 2463363

Strand: Direct

Name: qseC [H]

Synonym: Bind_2155

Alternate gene names: 182679118

Gene position: 2462014-2463363 (Clockwise)

Preceding gene: 182679117

Following gene: 182679119

Centisome position: 59.04

GC content: 50.15

Gene sequence:

>1350_bases
ATGAAGAGCTGGAGTCTCGCATCACGCATTGTCGCAAGCGTTCTCATCGTCATTTCCGGCTGCCTCGTCCTCCTCGGTCT
TTCCGTCGGTGCCTTCACGCGTTACGAGGTGACGGAACGGCTGGACAATTCCTTACAGGAAGTCTCGGAACGGCTGGAAT
TTGTTGCCTCCTCTAGTCAAGCGCAGATTCCAGAGAATGGCATCGCTCTCCTTCCCGGCGTCGATAAACGGACCCTCGCT
TATCAAATCGTTGCCCCTTCCGGTAACGTGCGCCTGCGATCGCAAAATGCCTCGCCGGAAGCCTTCGTGTATCCATTGAA
GGAAGGGTTTCATAATATCAAAGACTTTCGCGTCTATGTTACGCATTCAGCCGCGACACCCTATTACATCATCGTCGGTG
AACCCACCTTTCACCGCCAGGAAGCCGTGAGACGCGCGGTCCTCATTGTCATTTTGCCGATCGTGATATTCCTGCCCTGC
TCCTGGTTCCTGGTTCGCTTGACGGTCCTTCGTGCCTTGCGACCCTTGGTGCGATTGCAAACGGAAATAGGCAGCCGGGG
TGGCACCAACCTCGATCCGATTCCCTCTCTCGACCTCCCCAGTGAGATCGCGACGATCCATGCTGCCGTCAATTTGCTCT
TGAATCGTCTGAAAAAGGCACTCGCCACCGAACGGATGTTTGCGACCAACAGTGCACACGAATTGCGAAATCCAATCGCT
GGTCTTTTGGCGCAGACACAAATTCTCAACGATCAATTGAAAGGAAGCCAGTATGGCGCTCGTACACTTGCCATTGTCCA
GCAAACAAAACGCATTTCTCGTTTGACAGAAAAATTGCTGCAACTTTCAAGGGCCACATCCGGTGTTTCCTTGAAAAATG
AGCGTTTCGATCTGCTTCCTATTCTTTATTTGTTGATCGATGAATATTCGGACAAGGCGCCAAATGGTCCACCGATCAGG
ATGGAAACAGATCATATCAGTGATTTTTATATTTATGGAGACATCGACACGACTGGCATTCTCTTTCGGAATCTGATCGA
GAATGCAATCAATCATGGAGACAAGGATCACGGAATAGACATTCATGTTTCCAGCGATGGCTTTATTGACATCGTCAATG
AATGCACCGCCCTCGATCCAGCAATCCTGACTACAATCACCGATCCCTTCGTGCGCGGAAGCTCTTCCTCGAAAGGGGGA
GGACTCGGGCTGGCAATCGTCTATAATATTATAAGCCAGATGCACGGCCAGATGACGATCAAATCACCCATCCCTGGGCG
AGACACGGGCTTTGTCATCAGAGTTTCATTTGAGAATTTTAATATAATAATGGAAAAGTCTGAGCTCTAG

Upstream 100 bases:

>100_bases
ACGCAATCGAAGTTTTCGTGAGCCGAATTCGAAAAAAAGTGGGACGCAATATCATCCGTACGGTGCGAGGCCGCGGTTAT
TGTCTCGCGAGGTAACAGGA

Downstream 100 bases:

>100_bases
AAAACGACATAGGGTATGGGAAAAGCGATTGAGACTCAATCAACGGAAATCAGTTCCCAATAGAGTAAGGCCATTCAACT
GGCCTTATCTTCATTGAATC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKSWSLASRIVASVLIVISGCLVLLGLSVGAFTRYEVTERLDNSLQEVSERLEFVASSSQAQIPENGIALLPGVDKRTLA
YQIVAPSGNVRLRSQNASPEAFVYPLKEGFHNIKDFRVYVTHSAATPYYIIVGEPTFHRQEAVRRAVLIVILPIVIFLPC
SWFLVRLTVLRALRPLVRLQTEIGSRGGTNLDPIPSLDLPSEIATIHAAVNLLLNRLKKALATERMFATNSAHELRNPIA
GLLAQTQILNDQLKGSQYGARTLAIVQQTKRISRLTEKLLQLSRATSGVSLKNERFDLLPILYLLIDEYSDKAPNGPPIR
METDHISDFYIYGDIDTTGILFRNLIENAINHGDKDHGIDIHVSSDGFIDIVNECTALDPAILTTITDPFVRGSSSSKGG
GLGLAIVYNIISQMHGQMTIKSPIPGRDTGFVIRVSFENFNIIMEKSEL

Sequences:

>Translated_449_residues
MKSWSLASRIVASVLIVISGCLVLLGLSVGAFTRYEVTERLDNSLQEVSERLEFVASSSQAQIPENGIALLPGVDKRTLA
YQIVAPSGNVRLRSQNASPEAFVYPLKEGFHNIKDFRVYVTHSAATPYYIIVGEPTFHRQEAVRRAVLIVILPIVIFLPC
SWFLVRLTVLRALRPLVRLQTEIGSRGGTNLDPIPSLDLPSEIATIHAAVNLLLNRLKKALATERMFATNSAHELRNPIA
GLLAQTQILNDQLKGSQYGARTLAIVQQTKRISRLTEKLLQLSRATSGVSLKNERFDLLPILYLLIDEYSDKAPNGPPIR
METDHISDFYIYGDIDTTGILFRNLIENAINHGDKDHGIDIHVSSDGFIDIVNECTALDPAILTTITDPFVRGSSSSKGG
GLGLAIVYNIISQMHGQMTIKSPIPGRDTGFVIRVSFENFNIIMEKSEL
>Mature_449_residues
MKSWSLASRIVASVLIVISGCLVLLGLSVGAFTRYEVTERLDNSLQEVSERLEFVASSSQAQIPENGIALLPGVDKRTLA
YQIVAPSGNVRLRSQNASPEAFVYPLKEGFHNIKDFRVYVTHSAATPYYIIVGEPTFHRQEAVRRAVLIVILPIVIFLPC
SWFLVRLTVLRALRPLVRLQTEIGSRGGTNLDPIPSLDLPSEIATIHAAVNLLLNRLKKALATERMFATNSAHELRNPIA
GLLAQTQILNDQLKGSQYGARTLAIVQQTKRISRLTEKLLQLSRATSGVSLKNERFDLLPILYLLIDEYSDKAPNGPPIR
METDHISDFYIYGDIDTTGILFRNLIENAINHGDKDHGIDIHVSSDGFIDIVNECTALDPAILTTITDPFVRGSSSSKGG
GLGLAIVYNIISQMHGQMTIKSPIPGRDTGFVIRVSFENFNIIMEKSEL

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=309, Percent_Identity=28.1553398058252, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1789403, Length=433, Percent_Identity=26.5588914549654, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87082128, Length=302, Percent_Identity=25.8278145695364, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788279, Length=289, Percent_Identity=30.1038062283737, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=27.1966527196653, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=26.9911504424779, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=219, Percent_Identity=26.027397260274, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49569; Mature: 49569

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSWSLASRIVASVLIVISGCLVLLGLSVGAFTRYEVTERLDNSLQEVSERLEFVASSSQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQIPENGIALLPGVDKRTLAYQIVAPSGNVRLRSQNASPEAFVYPLKEGFHNIKDFRVYV
CCCCCCCEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEHHHHCCCCCEEEEEE
THSAATPYYIIVGEPTFHRQEAVRRAVLIVILPIVIFLPCSWFLVRLTVLRALRPLVRLQ
EECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEIGSRGGTNLDPIPSLDLPSEIATIHAAVNLLLNRLKKALATERMFATNSAHELRNPIA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GLLAQTQILNDQLKGSQYGARTLAIVQQTKRISRLTEKLLQLSRATSGVSLKNERFDLLP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ILYLLIDEYSDKAPNGPPIRMETDHISDFYIYGDIDTTGILFRNLIENAINHGDKDHGID
HHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEE
IHVSSDGFIDIVNECTALDPAILTTITDPFVRGSSSSKGGGLGLAIVYNIISQMHGQMTI
EEECCCCCHHHHHHHHCCCCHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
KSPIPGRDTGFVIRVSFENFNIIMEKSEL
CCCCCCCCCCEEEEEEECCCEEEEECCCC
>Mature Secondary Structure
MKSWSLASRIVASVLIVISGCLVLLGLSVGAFTRYEVTERLDNSLQEVSERLEFVASSSQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQIPENGIALLPGVDKRTLAYQIVAPSGNVRLRSQNASPEAFVYPLKEGFHNIKDFRVYV
CCCCCCCEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEHHHHCCCCCEEEEEE
THSAATPYYIIVGEPTFHRQEAVRRAVLIVILPIVIFLPCSWFLVRLTVLRALRPLVRLQ
EECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEIGSRGGTNLDPIPSLDLPSEIATIHAAVNLLLNRLKKALATERMFATNSAHELRNPIA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GLLAQTQILNDQLKGSQYGARTLAIVQQTKRISRLTEKLLQLSRATSGVSLKNERFDLLP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ILYLLIDEYSDKAPNGPPIRMETDHISDFYIYGDIDTTGILFRNLIENAINHGDKDHGID
HHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEE
IHVSSDGFIDIVNECTALDPAILTTITDPFVRGSSSSKGGGLGLAIVYNIISQMHGQMTI
EEECCCCCHHHHHHHHCCCCHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
KSPIPGRDTGFVIRVSFENFNIIMEKSEL
CCCCCCCCCCEEEEEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]