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The map label for this gene is czcB [H]

Identifier: 182679115

GI number: 182679115

Start: 2457083

End: 2458294

Strand: Direct

Name: czcB [H]

Synonym: Bind_2152

Alternate gene names: 182679115

Gene position: 2457083-2458294 (Clockwise)

Preceding gene: 182679114

Following gene: 182679116

Centisome position: 58.92

GC content: 55.2

Gene sequence:

>1212_bases
ATGAACATGTTCAAGTATAAGCTTCCTTTCAAGCTTCGGCTTCTCCTGATCGCCTTGTCGTTGTCGAATGTCTTTCCCCT
GCCCAATGCCAAAGCACAACAGACGCAGGAGACCAAGCCCGCACCTGCTCTCGATTATCAGCCCGTGAAATTAGGATCGG
ATGCACAAAAAAACGCGGAATTGGCGACTGTGATTGTGCATGACGGCACGCTTTCCCGCATCATCCCTGCCCTCGCCTCC
GTCATGGCCGATGATGCGCGGACACTTCATCTCAAGCCAGCCGGTTCCGGCAAGGTCATGAGCATCAATCTGATCCTCGG
GGCTAGGGTCGCCAAAGGCGATATCCTTCTCGAATACCGGGATAATGCGCTTCGCGTCGCCAATGTCCAGGTCACACAGG
CTCAGGCCGCCCTAGAGGCCGCGATTGCAGCCCAAGATGAGGCCGAGGCCGCCTATCAGCGTGCGCGGCAATTGGCTGGC
GGCGCCATATCACGTGGCGAAGTCAGCAGGCGTTATGCCTTGCTGCAAGAAGCCAAGAGCACCGTCGCGATGCGGCAGGC
AGATATTACCAACACATCCAATAGGATCAAAGAATTCAATACGGCAACGGAACAAGGTGATCATCTGCAGACATCATCGC
TTATCGCACCTGTCGATGGCCTCGTCCTCGCCGTCAATACGTCGATGGATGGCGATCTGACTGCCGGTCAAGACGTCGCG
ACAATCGTCGATCTCTCCTCCGTCTGGGTCGTATCGGAAGTCCCGCCTATGGACGCCGCTTTCATTACAATGGGAGCCCA
TCAATATAGTTTTCTTGCTGGTCGACCCGAAACGCGGATCGATTCCGTTGTCGAAACGATCGATGGTGTCGTCAATCCGG
CCACCGGCCTCATCCGTATCCGTAGCCACATTCCCAATAAGCACTATGCGCTCAGGCCCGGCATGATGCTGGAAGCCCGC
ATCACCTCAACCACCAAGATCAGTGGCGTTATCGTTCCCTCCGAGGCAGTCCAGCAAATTAACGGCAATGATGTCGTCTT
TATTCCGATCGATGCTGACAGCTTTCAACCGCGCGCCGTCAAGATCGGTCTCGAAAGCGATGGACAAACAATCATTCTCA
GTGGATTGAAGGACGGCGAATCCGTTGTCACGCGTGGGAGCTTTACCTTGAAATCGGTCATGCTTCTGGCCGATACGGCG
GGTGGAGATTGA

Upstream 100 bases:

>100_bases
ATCAAGGCGCCTACACCGCCATGCTGTCTCTCGATCAAGCTGAAACGGCCTGGCATGTGGCCGTTGCCCGAGTGTTTATT
GCCGCGGGGCATCTACAGTG

Downstream 100 bases:

>100_bases
GGTGAGCAAACTTCTCTCCCTTCTCCAGAACAATCGTTCCATCGTCATCGGCGTTCTCTTGATCCTCATGCTGTTTGGGA
TTGCGGACGTCACTCGTCTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNMFKYKLPFKLRLLLIALSLSNVFPLPNAKAQQTQETKPAPALDYQPVKLGSDAQKNAELATVIVHDGTLSRIIPALAS
VMADDARTLHLKPAGSGKVMSINLILGARVAKGDILLEYRDNALRVANVQVTQAQAALEAAIAAQDEAEAAYQRARQLAG
GAISRGEVSRRYALLQEAKSTVAMRQADITNTSNRIKEFNTATEQGDHLQTSSLIAPVDGLVLAVNTSMDGDLTAGQDVA
TIVDLSSVWVVSEVPPMDAAFITMGAHQYSFLAGRPETRIDSVVETIDGVVNPATGLIRIRSHIPNKHYALRPGMMLEAR
ITSTTKISGVIVPSEAVQQINGNDVVFIPIDADSFQPRAVKIGLESDGQTIILSGLKDGESVVTRGSFTLKSVMLLADTA
GGD

Sequences:

>Translated_403_residues
MNMFKYKLPFKLRLLLIALSLSNVFPLPNAKAQQTQETKPAPALDYQPVKLGSDAQKNAELATVIVHDGTLSRIIPALAS
VMADDARTLHLKPAGSGKVMSINLILGARVAKGDILLEYRDNALRVANVQVTQAQAALEAAIAAQDEAEAAYQRARQLAG
GAISRGEVSRRYALLQEAKSTVAMRQADITNTSNRIKEFNTATEQGDHLQTSSLIAPVDGLVLAVNTSMDGDLTAGQDVA
TIVDLSSVWVVSEVPPMDAAFITMGAHQYSFLAGRPETRIDSVVETIDGVVNPATGLIRIRSHIPNKHYALRPGMMLEAR
ITSTTKISGVIVPSEAVQQINGNDVVFIPIDADSFQPRAVKIGLESDGQTIILSGLKDGESVVTRGSFTLKSVMLLADTA
GGD
>Mature_403_residues
MNMFKYKLPFKLRLLLIALSLSNVFPLPNAKAQQTQETKPAPALDYQPVKLGSDAQKNAELATVIVHDGTLSRIIPALAS
VMADDARTLHLKPAGSGKVMSINLILGARVAKGDILLEYRDNALRVANVQVTQAQAALEAAIAAQDEAEAAYQRARQLAG
GAISRGEVSRRYALLQEAKSTVAMRQADITNTSNRIKEFNTATEQGDHLQTSSLIAPVDGLVLAVNTSMDGDLTAGQDVA
TIVDLSSVWVVSEVPPMDAAFITMGAHQYSFLAGRPETRIDSVVETIDGVVNPATGLIRIRSHIPNKHYALRPGMMLEAR
ITSTTKISGVIVPSEAVQQINGNDVVFIPIDADSFQPRAVKIGLESDGQTIILSGLKDGESVVTRGSFTLKSVMLLADTA
GGD

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=330, Percent_Identity=23.3333333333333, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786787, Length=266, Percent_Identity=27.4436090225564, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43004; Mature: 43004

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMFKYKLPFKLRLLLIALSLSNVFPLPNAKAQQTQETKPAPALDYQPVKLGSDAQKNAE
CCCEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEECCCCCCCCCE
LATVIVHDGTLSRIIPALASVMADDARTLHLKPAGSGKVMSINLILGARVAKGDILLEYR
EEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEECEEECCCEEEEEC
DNALRVANVQVTQAQAALEAAIAAQDEAEAAYQRARQLAGGAISRGEVSRRYALLQEAKS
CCEEEEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
TVAMRQADITNTSNRIKEFNTATEQGDHLQTSSLIAPVDGLVLAVNTSMDGDLTAGQDVA
HHHHHHHCCCCCHHHHHHHCCHHCCCCCEECCCEECCCCCEEEEEECCCCCCCCCCCCCE
TIVDLSSVWVVSEVPPMDAAFITMGAHQYSFLAGRPETRIDSVVETIDGVVNPATGLIRI
EEEECCCEEEEECCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHEEEE
RSHIPNKHYALRPGMMLEARITSTTKISGVIVPSEAVQQINGNDVVFIPIDADSFQPRAV
EHHCCCCCEEECCCCEEEEEECCCEEEEEEEECHHHHHHCCCCEEEEEEECCCCCCCEEE
KIGLESDGQTIILSGLKDGESVVTRGSFTLKSVMLLADTAGGD
EEEECCCCCEEEEECCCCCCHHEECCCHHHHEEEEEEECCCCC
>Mature Secondary Structure
MNMFKYKLPFKLRLLLIALSLSNVFPLPNAKAQQTQETKPAPALDYQPVKLGSDAQKNAE
CCCEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEECCCCCCCCCE
LATVIVHDGTLSRIIPALASVMADDARTLHLKPAGSGKVMSINLILGARVAKGDILLEYR
EEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEECEEECCCEEEEEC
DNALRVANVQVTQAQAALEAAIAAQDEAEAAYQRARQLAGGAISRGEVSRRYALLQEAKS
CCEEEEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
TVAMRQADITNTSNRIKEFNTATEQGDHLQTSSLIAPVDGLVLAVNTSMDGDLTAGQDVA
HHHHHHHCCCCCHHHHHHHCCHHCCCCCEECCCEECCCCCEEEEEECCCCCCCCCCCCCE
TIVDLSSVWVVSEVPPMDAAFITMGAHQYSFLAGRPETRIDSVVETIDGVVNPATGLIRI
EEEECCCEEEEECCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHEEEE
RSHIPNKHYALRPGMMLEARITSTTKISGVIVPSEAVQQINGNDVVFIPIDADSFQPRAV
EHHCCCCCEEECCCCEEEEEECCCEEEEEEEECHHHHHHCCCCEEEEEEECCCCCCCEEE
KIGLESDGQTIILSGLKDGESVVTRGSFTLKSVMLLADTAGGD
EEEECCCCCEEEEECCCCCCHHEECCCHHHHEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]