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The map label for this gene is dinB2 [H]

Identifier: 182679061

GI number: 182679061

Start: 2396921

End: 2398042

Strand: Reverse

Name: dinB2 [H]

Synonym: Bind_2097

Alternate gene names: 182679061

Gene position: 2398042-2396921 (Counterclockwise)

Preceding gene: 182679062

Following gene: 182679059

Centisome position: 57.5

GC content: 58.56

Gene sequence:

>1122_bases
ATGGGGGAGGGCGGGAACGGCGGCAATACGATGCCGCCGCATCAGCGCAAAATCATTCATATCGACATGGATGCCTTCTA
CGCTTCCGTCGAGCAGCGCGATGATCCTGGGCTGCGTGGCCGGCCGGTTGCTGTCGGGAGCGCACGGGCGCGCGGCGTTG
TTGCTGCGGCGAGCTACGAGGCCCGAAAATTCGGTGTCCATTCGGCTATGCCTTCCGTGACGGCTTTGCGCAAATGCCCA
GATTTGATTTTCGTGCCGCCGCGTTTCGATATCTATAAAGCGGTATCGCGGCGCATACGCGCGATTTTTGCCGAACATAC
AGCTCTCATCGAACCGCTTTCGCTCGATGAGGCCTATCTCGATGTCACGAGCAATTTACGGAATGTCGCATCAGCGACCG
AGATCGCGGAACAGATCCGCGCGAGAATTTTGGCGGAAACGGGACTCACCGCCTCGGCGGGTGTCTCTTATAATAAATTT
CTGGCCAAGCTCGCCTCGGATCACAACAAGCCGAACGGGCTATTCGTCATCACGCCCAAAATGGGGCCTGGTTTTGTCGA
GGCTCTGCCAGTCAGCAAGTTCCACGGGATCGGCCCTGCGACGGCGGCCAAGATGGAAAAACTTGCGATCGCGACCGGCC
GCGATTTAAAGGCGCGGCCGCTTGCCTTCCTGCAACAGCATTTCGGCAAAGCTGGAACCTATTATTACTGGATCGCGCGC
GGCGTTGACGAACGCCCGGTGCGGCCGGACAGGGAACGCAAGTCGATTGGAGCCGAAAATACCTTCGCAATCGATCTCTA
CACTTTCGAGGCAGCCTATGCCGCTTTGACGCCGATCATGGAGAAAGTCTGGCGTTCTCGCGAGATGATGAATCTGCGCG
CCAGGACCGTGACCCTCAAGGTGAAATATGCCGATTTTCAGCAGATCACGCGCAGCCGGACCGATGACGAGGGGATTGTG
ACGCGGGTTCTGTTTGAGGAAAGGGTCGCCAGCCTGCTGGCGCCGCTTTTCCCCACCACGAAGGGGATCAGGCTTTTGGG
AGTGACCCTCTCCGCTTTCGCAAAACCCGAGCCCGAGGCAGTGGGGCAGCTCAGCTTCCTGTTCGAGCAGGAAATCGGCT
GA

Upstream 100 bases:

>100_bases
GCGCCTTTGCGGATGCGCCGGGAACCTATGTGCTCGAAGCTTGACCGGGTGAGTGGATAGCTCTCTATTCCACGGCAGGG
TGAGAGAGGATCAGGCCAGT

Downstream 100 bases:

>100_bases
ATATGGTTTTTCGGTTTTCTGCGCTTTATCCCACCGGCTGCAGATGCAGACGATAGCGTTGCGCGCGTTCGCGATAGGTC
TTGGCGGTTCGCGCTATATT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MGEGGNGGNTMPPHQRKIIHIDMDAFYASVEQRDDPGLRGRPVAVGSARARGVVAAASYEARKFGVHSAMPSVTALRKCP
DLIFVPPRFDIYKAVSRRIRAIFAEHTALIEPLSLDEAYLDVTSNLRNVASATEIAEQIRARILAETGLTASAGVSYNKF
LAKLASDHNKPNGLFVITPKMGPGFVEALPVSKFHGIGPATAAKMEKLAIATGRDLKARPLAFLQQHFGKAGTYYYWIAR
GVDERPVRPDRERKSIGAENTFAIDLYTFEAAYAALTPIMEKVWRSREMMNLRARTVTLKVKYADFQQITRSRTDDEGIV
TRVLFEERVASLLAPLFPTTKGIRLLGVTLSAFAKPEPEAVGQLSFLFEQEIG

Sequences:

>Translated_373_residues
MGEGGNGGNTMPPHQRKIIHIDMDAFYASVEQRDDPGLRGRPVAVGSARARGVVAAASYEARKFGVHSAMPSVTALRKCP
DLIFVPPRFDIYKAVSRRIRAIFAEHTALIEPLSLDEAYLDVTSNLRNVASATEIAEQIRARILAETGLTASAGVSYNKF
LAKLASDHNKPNGLFVITPKMGPGFVEALPVSKFHGIGPATAAKMEKLAIATGRDLKARPLAFLQQHFGKAGTYYYWIAR
GVDERPVRPDRERKSIGAENTFAIDLYTFEAAYAALTPIMEKVWRSREMMNLRARTVTLKVKYADFQQITRSRTDDEGIV
TRVLFEERVASLLAPLFPTTKGIRLLGVTLSAFAKPEPEAVGQLSFLFEQEIG
>Mature_372_residues
GEGGNGGNTMPPHQRKIIHIDMDAFYASVEQRDDPGLRGRPVAVGSARARGVVAAASYEARKFGVHSAMPSVTALRKCPD
LIFVPPRFDIYKAVSRRIRAIFAEHTALIEPLSLDEAYLDVTSNLRNVASATEIAEQIRARILAETGLTASAGVSYNKFL
AKLASDHNKPNGLFVITPKMGPGFVEALPVSKFHGIGPATAAKMEKLAIATGRDLKARPLAFLQQHFGKAGTYYYWIARG
VDERPVRPDRERKSIGAENTFAIDLYTFEAAYAALTPIMEKVWRSREMMNLRARTVTLKVKYADFQQITRSRTDDEGIVT
RVLFEERVASLLAPLFPTTKGIRLLGVTLSAFAKPEPEAVGQLSFLFEQEIG

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=344, Percent_Identity=31.3953488372093, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI7706681, Length=345, Percent_Identity=31.304347826087, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI7705344, Length=109, Percent_Identity=51.3761467889908, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI154350220, Length=284, Percent_Identity=29.2253521126761, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI5729982, Length=319, Percent_Identity=29.153605015674, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1786425, Length=359, Percent_Identity=44.5682451253482, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI1787432, Length=218, Percent_Identity=31.651376146789, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=412, Percent_Identity=30.0970873786408, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17537959, Length=356, Percent_Identity=28.3707865168539, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=359, Percent_Identity=27.5766016713092, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=322, Percent_Identity=28.8819875776398, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19923006, Length=343, Percent_Identity=26.2390670553936, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355641, Length=286, Percent_Identity=30.7692307692308, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24644984, Length=286, Percent_Identity=30.7692307692308, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24668444, Length=249, Percent_Identity=28.1124497991968, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 41067; Mature: 40936

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEGGNGGNTMPPHQRKIIHIDMDAFYASVEQRDDPGLRGRPVAVGSARARGVVAAASYE
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEECCHH
ARKFGVHSAMPSVTALRKCPDLIFVPPRFDIYKAVSRRIRAIFAEHTALIEPLSLDEAYL
HHHHCHHHCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DVTSNLRNVASATEIAEQIRARILAETGLTASAGVSYNKFLAKLASDHNKPNGLFVITPK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
MGPGFVEALPVSKFHGIGPATAAKMEKLAIATGRDLKARPLAFLQQHFGKAGTYYYWIAR
CCCCHHHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
GVDERPVRPDRERKSIGAENTFAIDLYTFEAAYAALTPIMEKVWRSREMMNLRARTVTLK
CCCCCCCCCCHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEE
VKYADFQQITRSRTDDEGIVTRVLFEERVASLLAPLFPTTKGIRLLGVTLSAFAKPEPEA
EEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCCHHH
VGQLSFLFEQEIG
HHHHHHHHHHCCC
>Mature Secondary Structure 
GEGGNGGNTMPPHQRKIIHIDMDAFYASVEQRDDPGLRGRPVAVGSARARGVVAAASYE
CCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEECCHH
ARKFGVHSAMPSVTALRKCPDLIFVPPRFDIYKAVSRRIRAIFAEHTALIEPLSLDEAYL
HHHHCHHHCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DVTSNLRNVASATEIAEQIRARILAETGLTASAGVSYNKFLAKLASDHNKPNGLFVITPK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
MGPGFVEALPVSKFHGIGPATAAKMEKLAIATGRDLKARPLAFLQQHFGKAGTYYYWIAR
CCCCHHHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
GVDERPVRPDRERKSIGAENTFAIDLYTFEAAYAALTPIMEKVWRSREMMNLRARTVTLK
CCCCCCCCCCHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEE
VKYADFQQITRSRTDDEGIVTRVLFEERVASLLAPLFPTTKGIRLLGVTLSAFAKPEPEA
EEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCCHHH
VGQLSFLFEQEIG
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]