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The map label for this gene is wrbA

Identifier: 182678899

GI number: 182678899

Start: 2203038

End: 2203637

Strand: Direct

Name: wrbA

Synonym: Bind_1932

Alternate gene names: 182678899

Gene position: 2203038-2203637 (Clockwise)

Preceding gene: 182678897

Following gene: 182678900

Centisome position: 52.83

GC content: 60.5

Gene sequence:

>600_bases
ATGCCAAAAGTTCTCGTTCTTTATTATTCTTCCTATGGCCATATCGAGACGATGGCGGAAGCCGTCGCAGAAGGCGCGCG
GGCGGCGGGCGCTGAGGCCGATGTGAAACGCGTGCCGGAGCTGGTGCCGGAGCCGGTCGCCAAAGCGCATTTCTTCAAGC
TTGACCAAGGCGCACCCATCGCGACGCCCGAAGACCTCGTCAATTATGACGCGATCATCATCGGCGCCCCGACCCGCTTC
GGACGCCTGCCCGCGCAAATGGCTAATTTCTGGGATATGACCGGCGGTCTGTGGCTGAAGGGTGCCCTGATTGGCAAGGT
GGGCGCAGCCTTTACCTCGACCGCTGTGCAGCATGGCGGCCAGGAAACCACGCTCTATTCCTTGCTCACGAACCTGATCC
ATCACGGCATGGTCGTCGCCGGCCTTCCTTATAGTTTTGCCGGCCAGATGAATATGAACGAAATCACCGGCGGCTCACCC
TATGGCGCGACGACGATCGCCAATGGCGACGGATCGCGCGCGGTCAGCGCCAATGAACAAGAAGGCGCGAAATTCCTCGG
CCGGCATGTGGCGGAAATCGCCCAGAAGCTGAACGCCTGA

Upstream 100 bases:

>100_bases
TCTCCTCGACGGCCAATCGAGCGGGACACGCGACAGCGCGAGATCCCCTCGACTGGCCAGCCTCAAGCCGAAAATATTCG
GCCCGCGGCAGGAGACCATG

Downstream 100 bases:

>100_bases
TCCAACCTCTTCTTTTCTTCTTCCAAACGAGTCACCTCTGATGAAATCTTCTTTTCTTTTTGCCCTTTCCTTCAAATCGG
CCTTTTTGGCTTATGGCCTC

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPKVLVLYYSSYGHIETMAEAVAEGARAAGAEADVKRVPELVPEPVAKAHFFKLDQGAPIATPEDLVNYDAIIIGAPTRF
GRLPAQMANFWDMTGGLWLKGALIGKVGAAFTSTAVQHGGQETTLYSLLTNLIHHGMVVAGLPYSFAGQMNMNEITGGSP
YGATTIANGDGSRAVSANEQEGAKFLGRHVAEIAQKLNA

Sequences:

>Translated_199_residues
MPKVLVLYYSSYGHIETMAEAVAEGARAAGAEADVKRVPELVPEPVAKAHFFKLDQGAPIATPEDLVNYDAIIIGAPTRF
GRLPAQMANFWDMTGGLWLKGALIGKVGAAFTSTAVQHGGQETTLYSLLTNLIHHGMVVAGLPYSFAGQMNMNEITGGSP
YGATTIANGDGSRAVSANEQEGAKFLGRHVAEIAQKLNA
>Mature_198_residues
PKVLVLYYSSYGHIETMAEAVAEGARAAGAEADVKRVPELVPEPVAKAHFFKLDQGAPIATPEDLVNYDAIIIGAPTRFG
RLPAQMANFWDMTGGLWLKGALIGKVGAAFTSTAVQHGGQETTLYSLLTNLIHHGMVVAGLPYSFAGQMNMNEITGGSPY
GATTIANGDGSRAVSANEQEGAKFLGRHVAEIAQKLNA

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain

Homologues:

Organism=Escherichia coli, GI1787239, Length=199, Percent_Identity=54.2713567839196, Blast_Score=198, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6319849, Length=200, Percent_Identity=46, Blast_Score=174, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=45.7286432160804, Blast_Score=161, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6319526, Length=201, Percent_Identity=33.8308457711443, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WRBA_BEII9 (B2IEF8)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001833045.1
- ProteinModelPortal:   B2IEF8
- GeneID:   6199577
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_1932
- HOGENOM:   HBG686708
- OMA:   PYSHQGQ
- ProtClustDB:   PRK03767
- HAMAP:   MF_01017
- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025
- TIGRFAMs:   TIGR01755

Pfam domain/function: PF03358 FMN_red

EC number: NA

Molecular weight: Translated: 20972; Mature: 20841

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVLVLYYSSYGHIETMAEAVAEGARAAGAEADVKRVPELVPEPVAKAHFFKLDQGAPI
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHEECCCCCCC
ATPEDLVNYDAIIIGAPTRFGRLPAQMANFWDMTGGLWLKGALIGKVGAAFTSTAVQHGG
CCHHHHHCCCEEEEECCCHHHCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCC
QETTLYSLLTNLIHHGMVVAGLPYSFAGQMNMNEITGGSPYGATTIANGDGSRAVSANEQ
CHHHHHHHHHHHHHCCEEEECCCCHHCCCCCCHHCCCCCCCCCCEEECCCCCCCCCCCHH
EGAKFLGRHVAEIAQKLNA
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKVLVLYYSSYGHIETMAEAVAEGARAAGAEADVKRVPELVPEPVAKAHFFKLDQGAPI
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHEECCCCCCC
ATPEDLVNYDAIIIGAPTRFGRLPAQMANFWDMTGGLWLKGALIGKVGAAFTSTAVQHGG
CCHHHHHCCCEEEEECCCHHHCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCC
QETTLYSLLTNLIHHGMVVAGLPYSFAGQMNMNEITGGSPYGATTIANGDGSRAVSANEQ
CHHHHHHHHHHHHHCCEEEECCCCHHCCCCCCHHCCCCCCCCCCEEECCCCCCCCCCCHH
EGAKFLGRHVAEIAQKLNA
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA