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The map label for this gene is rsmB [H]

Identifier: 182678888

GI number: 182678888

Start: 2190284

End: 2191576

Strand: Reverse

Name: rsmB [H]

Synonym: Bind_1921

Alternate gene names: 182678888

Gene position: 2191576-2190284 (Counterclockwise)

Preceding gene: 182678889

Following gene: 182678886

Centisome position: 52.55

GC content: 63.11

Gene sequence:

>1293_bases
ATGATACCTGCCGCCCGTCTGAGCGCCGCGATTGAAATTCTCGCTGACATTGAAACCCGCCGCCGCCCTGCTGCCGATGC
CGTAAAAGATTGGGGCCTTGCCCATCGTTTCGCTGGATCGAAGGATCGCGCCGCCATTGCGGGCCTCGTCTATGACGCCT
TGCGGCGCAAGGCGTCATCGGCCTGGATCATGGGCGAGGACACTCCCCGCGCGGTTTTGCTTGGGTCCTTGCGGCAGGTG
CAAGGCCTGCCTCTGGATGCCGTCGAAGCTTTGTTCAGTGGCGAGGGCCATGCGCCGGCTCTTTTGAGCGATGCGGAAAA
GCAGCGCTATCGTGATGGCACTCTCGATGATGCGCCGGCCTCTGTCGCGGGCGACTTCCCGCAATGGCTGGAACCCGCCT
TTCAGCGCGTCTTCGGCGCCCTGGCGGCGGCGGAAGGCGAGGCGCTTGCCGCCCGTGCGCCGCTTGATCTGCGCGTCAAT
CTGCTGAAAGGGGATCGCGCCAAGGCGATCAAAGCCTTGGCCCATCTCAAGCCAGAACCCACACCTTATTCGCCCTTCGG
CCTGCGCCTGCCGCTTTTGCCTGATGGCCGCGCCGCGCCGCTTGTGGCCGAGGCGGCTTACGTCAAAGGTCTGGTCGAGG
TGCAGGACGAAGGCTCGCAACTCGCCGCGCTTCTCGCCCATGCCAAGCCGGGGGAACAGGTTCTGGACTTATGCGCCGGT
GGCGGCGGCAAGACCCTGGCTCTGGCAGCCTTGATGAACAATAAGGGCCAGATTTATGCGAGCGACAATGATGGCCGCAG
GCTCGCGCCGATCCATGAAAGGCTCAAACGCGCTGACGTGCGCAATGTGCAGGTGCGCGCGCCGCGCGGCCGTGTGGCAA
AGCTCGATGATTTGGAAGGACGCTGCGATCTCGTTTTCGTCGATGCGCCGTGTACAGGCACGGGCACATGGCGGCGCAAC
CCCGACGCCAAATGGCGGATCAGACCGGGTGCGCTGGAAGAACGGATCAAGCAACAGAATGAAACCCTCGCCACGGCCGC
CCGCTATGTAAAGCCGGGCGGGCGGATTGTGTATGCGACCTGCTCGGTCCTGGCCGAAGAGAACGAAGACCGGATTACGG
ATTTCTTGAAGGAGAACGCCGGTTTTCAAGCAAGGCCAGCGGGAGACATGGCGCGGGAGGCTGGTCTTCCGATGCTGGCC
GATTTCGCCTCGACGTTGGGACCGGGTTTGCGGCTGACGCCGAGGACAAGCGGGACCGATGGTTTCTATGTGGTGGAATT
GACGCGTGAATAA

Upstream 100 bases:

>100_bases
CCTCGCGCGGCAATTGGTTTGCCGTTGGCAGTTCCATCCTGTTGTTGATGTGGGCTTTCTTCGCGGTGCGTTTGTTCCTC
TCCCCACCCATTGAGATCTG

Downstream 100 bases:

>100_bases
TACCAAAGGTCGTAAAGAACGGCCTTTGGTTCCTTTCTTGAATTTTCGCTTTTACAAAGCGAGAGCGAAAATTCAAGAGC
GGTCCAACGGTCTTGATCAT

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MIPAARLSAAIEILADIETRRRPAADAVKDWGLAHRFAGSKDRAAIAGLVYDALRRKASSAWIMGEDTPRAVLLGSLRQV
QGLPLDAVEALFSGEGHAPALLSDAEKQRYRDGTLDDAPASVAGDFPQWLEPAFQRVFGALAAAEGEALAARAPLDLRVN
LLKGDRAKAIKALAHLKPEPTPYSPFGLRLPLLPDGRAAPLVAEAAYVKGLVEVQDEGSQLAALLAHAKPGEQVLDLCAG
GGGKTLALAALMNNKGQIYASDNDGRRLAPIHERLKRADVRNVQVRAPRGRVAKLDDLEGRCDLVFVDAPCTGTGTWRRN
PDAKWRIRPGALEERIKQQNETLATAARYVKPGGRIVYATCSVLAEENEDRITDFLKENAGFQARPAGDMAREAGLPMLA
DFASTLGPGLRLTPRTSGTDGFYVVELTRE

Sequences:

>Translated_430_residues
MIPAARLSAAIEILADIETRRRPAADAVKDWGLAHRFAGSKDRAAIAGLVYDALRRKASSAWIMGEDTPRAVLLGSLRQV
QGLPLDAVEALFSGEGHAPALLSDAEKQRYRDGTLDDAPASVAGDFPQWLEPAFQRVFGALAAAEGEALAARAPLDLRVN
LLKGDRAKAIKALAHLKPEPTPYSPFGLRLPLLPDGRAAPLVAEAAYVKGLVEVQDEGSQLAALLAHAKPGEQVLDLCAG
GGGKTLALAALMNNKGQIYASDNDGRRLAPIHERLKRADVRNVQVRAPRGRVAKLDDLEGRCDLVFVDAPCTGTGTWRRN
PDAKWRIRPGALEERIKQQNETLATAARYVKPGGRIVYATCSVLAEENEDRITDFLKENAGFQARPAGDMAREAGLPMLA
DFASTLGPGLRLTPRTSGTDGFYVVELTRE
>Mature_430_residues
MIPAARLSAAIEILADIETRRRPAADAVKDWGLAHRFAGSKDRAAIAGLVYDALRRKASSAWIMGEDTPRAVLLGSLRQV
QGLPLDAVEALFSGEGHAPALLSDAEKQRYRDGTLDDAPASVAGDFPQWLEPAFQRVFGALAAAEGEALAARAPLDLRVN
LLKGDRAKAIKALAHLKPEPTPYSPFGLRLPLLPDGRAAPLVAEAAYVKGLVEVQDEGSQLAALLAHAKPGEQVLDLCAG
GGGKTLALAALMNNKGQIYASDNDGRRLAPIHERLKRADVRNVQVRAPRGRVAKLDDLEGRCDLVFVDAPCTGTGTWRRN
PDAKWRIRPGALEERIKQQNETLATAARYVKPGGRIVYATCSVLAEENEDRITDFLKENAGFQARPAGDMAREAGLPMLA
DFASTLGPGLRLTPRTSGTDGFYVVELTRE

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=290, Percent_Identity=30, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI76150623, Length=290, Percent_Identity=30, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI23199998, Length=256, Percent_Identity=32.421875, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI8922322, Length=257, Percent_Identity=32.6848249027237, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI270288818, Length=256, Percent_Identity=32.421875, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI270288816, Length=257, Percent_Identity=32.6848249027237, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI32698918, Length=199, Percent_Identity=30.6532663316583, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI11545785, Length=222, Percent_Identity=28.3783783783784, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI39995082, Length=238, Percent_Identity=28.9915966386555, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI301336155, Length=238, Percent_Identity=28.9915966386555, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI2367212, Length=414, Percent_Identity=28.2608695652174, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI87081985, Length=299, Percent_Identity=30.7692307692308, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17536757, Length=282, Percent_Identity=30.1418439716312, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115534021, Length=235, Percent_Identity=30.2127659574468, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71998419, Length=235, Percent_Identity=30.2127659574468, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25143471, Length=193, Percent_Identity=33.160621761658, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324268, Length=308, Percent_Identity=26.2987012987013, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319447, Length=194, Percent_Identity=29.3814432989691, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI22024126, Length=291, Percent_Identity=30.2405498281787, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24668781, Length=169, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356513, Length=169, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19920494, Length=206, Percent_Identity=27.6699029126214, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355201, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46194; Mature: 46194

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPAARLSAAIEILADIETRRRPAADAVKDWGLAHRFAGSKDRAAIAGLVYDALRRKASS
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCC
AWIMGEDTPRAVLLGSLRQVQGLPLDAVEALFSGEGHAPALLSDAEKQRYRDGTLDDAPA
CEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCC
SVAGDFPQWLEPAFQRVFGALAAAEGEALAARAPLDLRVNLLKGDRAKAIKALAHLKPEP
HHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCCHHHHHHHHHHCCCCC
TPYSPFGLRLPLLPDGRAAPLVAEAAYVKGLVEVQDEGSQLAALLAHAKPGEQVLDLCAG
CCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCC
GGGKTLALAALMNNKGQIYASDNDGRRLAPIHERLKRADVRNVQVRAPRGRVAKLDDLEG
CCCCCEEEEEECCCCCEEEECCCCCCEECHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC
RCDLVFVDAPCTGTGTWRRNPDAKWRIRPGALEERIKQQNETLATAARYVKPGGRIVYAT
CCCEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
CSVLAEENEDRITDFLKENAGFQARPAGDMAREAGLPMLADFASTLGPGLRLTPRTSGTD
EHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCEECCCCCCCC
GFYVVELTRE
CEEEEEEECC
>Mature Secondary Structure
MIPAARLSAAIEILADIETRRRPAADAVKDWGLAHRFAGSKDRAAIAGLVYDALRRKASS
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCC
AWIMGEDTPRAVLLGSLRQVQGLPLDAVEALFSGEGHAPALLSDAEKQRYRDGTLDDAPA
CEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCC
SVAGDFPQWLEPAFQRVFGALAAAEGEALAARAPLDLRVNLLKGDRAKAIKALAHLKPEP
HHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCCHHHHHHHHHHCCCCC
TPYSPFGLRLPLLPDGRAAPLVAEAAYVKGLVEVQDEGSQLAALLAHAKPGEQVLDLCAG
CCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCC
GGGKTLALAALMNNKGQIYASDNDGRRLAPIHERLKRADVRNVQVRAPRGRVAKLDDLEG
CCCCCEEEEEECCCCCEEEECCCCCCEECHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC
RCDLVFVDAPCTGTGTWRRNPDAKWRIRPGALEERIKQQNETLATAARYVKPGGRIVYAT
CCCEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
CSVLAEENEDRITDFLKENAGFQARPAGDMAREAGLPMLADFASTLGPGLRLTPRTSGTD
EHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCEECCCCCCCC
GFYVVELTRE
CEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]