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The map label for this gene is exoB [H]

Identifier: 182678833

GI number: 182678833

Start: 2126705

End: 2127697

Strand: Direct

Name: exoB [H]

Synonym: Bind_1866

Alternate gene names: 182678833

Gene position: 2126705-2127697 (Clockwise)

Preceding gene: 182678832

Following gene: 182678834

Centisome position: 51.0

GC content: 58.01

Gene sequence:

>993_bases
ATGAGCGTACTGGTCACGGGCGGTGCGGGTTACATCGGCGGCCATATGGTTTTGGGCCTCCTCGATGCCGGGCAGAAAGT
CGTCGTTCTCGATAATCTTTCGACCGGGTTCTCCTGGGCGGTGCCGCAAGGCGTCGATCTGATCATTGGCGATTTCGGCG
ATCAAGCTTTGGTCGACCGGGTTCTTGCCGACCATCACATTGATGCCATCGCCCATTTCGGTGCGAAAATCGTCGTGCCA
GAATCCGTGACCGATCCTCTAGGGTATTATCTCAACAATACGGCCAAGGCGCGCAATCTGATTGAATGTGCCGCGAAAAG
CGGCGTCAAACATTTCATCTTTTCATCCACCGCCGCTGTCTATGGCGAGCCAAAGGCTAATCCTGTTTTCGAGGACGCCC
CGCTTACGCCCATCAACCCCTACGGCCGTTCCAAGCTGATGGTCGAATGGATGCTCGAGGATGTCGCCAAGGCGCATGCC
CTCACCTATGCGATCCTGCGCTATTTCAATGTGGCCGGCGCCGATCCGCAAGGCCGGCTCGGACAAGCCTCACCCGTCGC
CACGCATCTCATCAAGATCGCGGTGCAGGCCGCGCTCGGTTTTCGCAAGGGGATGGATGTCTATGGCACGGATTACCCGA
CGCCGGACGGTTCCTGCGTACGCGATTATATTCAGGTCACCGATCTCGTCGATGCGCATTTGCTGGCACTCGATTATTTG
CGCCAGGGTGGCGAGAGCCTGACCTGCAATTGCGGTTATGGGCGCGGTCTTTCGGTGCTGGACGTCATCCGCACGGTCAA
GGCAGTGAGCGGCGTCGATTTCGAAGTGCGGATCGCCGGACGCCGCGCGGGTGATCCAGCCTCACTGATTGCTGGCGCCA
CGCACGTGCGCGATCTTTTGGGTTGGCAACCCAAACATGATCATGTCGAAGAAATGGTCAAACAGGCGCTCGATTGGGAA
CGCCGCCTGCACAATATTAAAGGGCAAGCCTAA

Upstream 100 bases:

>100_bases
GAATTGTTGATTTCATAGGCAAAAGCCATAGACCAGAGCCATTGAAGGCCATAACGTTTCCGCATTCGGCTTTTGGAGAA
TCGGGCTGGCGAGGGCAAGG

Downstream 100 bases:

>100_bases
TCCTCCGGCAGAAGTCTAGCTCCGCATTTTCGGACTCCGATCGTGATCGATTTCTCCGCCTATTCGCTCGGCTCCATTTT
CGCAGCGAGCCTGATCGTGC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSVLVTGGAGYIGGHMVLGLLDAGQKVVVLDNLSTGFSWAVPQGVDLIIGDFGDQALVDRVLADHHIDAIAHFGAKIVVP
ESVTDPLGYYLNNTAKARNLIECAAKSGVKHFIFSSTAAVYGEPKANPVFEDAPLTPINPYGRSKLMVEWMLEDVAKAHA
LTYAILRYFNVAGADPQGRLGQASPVATHLIKIAVQAALGFRKGMDVYGTDYPTPDGSCVRDYIQVTDLVDAHLLALDYL
RQGGESLTCNCGYGRGLSVLDVIRTVKAVSGVDFEVRIAGRRAGDPASLIAGATHVRDLLGWQPKHDHVEEMVKQALDWE
RRLHNIKGQA

Sequences:

>Translated_330_residues
MSVLVTGGAGYIGGHMVLGLLDAGQKVVVLDNLSTGFSWAVPQGVDLIIGDFGDQALVDRVLADHHIDAIAHFGAKIVVP
ESVTDPLGYYLNNTAKARNLIECAAKSGVKHFIFSSTAAVYGEPKANPVFEDAPLTPINPYGRSKLMVEWMLEDVAKAHA
LTYAILRYFNVAGADPQGRLGQASPVATHLIKIAVQAALGFRKGMDVYGTDYPTPDGSCVRDYIQVTDLVDAHLLALDYL
RQGGESLTCNCGYGRGLSVLDVIRTVKAVSGVDFEVRIAGRRAGDPASLIAGATHVRDLLGWQPKHDHVEEMVKQALDWE
RRLHNIKGQA
>Mature_329_residues
SVLVTGGAGYIGGHMVLGLLDAGQKVVVLDNLSTGFSWAVPQGVDLIIGDFGDQALVDRVLADHHIDAIAHFGAKIVVPE
SVTDPLGYYLNNTAKARNLIECAAKSGVKHFIFSSTAAVYGEPKANPVFEDAPLTPINPYGRSKLMVEWMLEDVAKAHAL
TYAILRYFNVAGADPQGRLGQASPVATHLIKIAVQAALGFRKGMDVYGTDYPTPDGSCVRDYIQVTDLVDAHLLALDYLR
QGGESLTCNCGYGRGLSVLDVIRTVKAVSGVDFEVRIAGRRAGDPASLIAGATHVRDLLGWQPKHDHVEEMVKQALDWER
RLHNIKGQA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=35.9050445103858, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=35.9050445103858, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=35.9050445103858, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI42516563, Length=330, Percent_Identity=25.4545454545455, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7657641, Length=347, Percent_Identity=25.3602305475504, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=39.4578313253012, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1790049, Length=334, Percent_Identity=26.9461077844311, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994969, Length=349, Percent_Identity=26.0744985673352, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982038, Length=343, Percent_Identity=36.734693877551, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71982035, Length=341, Percent_Identity=36.6568914956012, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17539532, Length=332, Percent_Identity=24.3975903614458, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17568069, Length=249, Percent_Identity=28.5140562248996, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=36.4179104477612, Blast_Score=202, Evalue=6e-53,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=38.8888888888889, Blast_Score=217, Evalue=7e-57,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=26.031746031746, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35511; Mature: 35380

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVTGGAGYIGGHMVLGLLDAGQKVVVLDNLSTGFSWAVPQGVDLIIGDFGDQALVDR
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHH
VLADHHIDAIAHFGAKIVVPESVTDPLGYYLNNTAKARNLIECAAKSGVKHFIFSSTAAV
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCHHC
YGEPKANPVFEDAPLTPINPYGRSKLMVEWMLEDVAKAHALTYAILRYFNVAGADPQGRL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQASPVATHLIKIAVQAALGFRKGMDVYGTDYPTPDGSCVRDYIQVTDLVDAHLLALDYL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQGGESLTCNCGYGRGLSVLDVIRTVKAVSGVDFEVRIAGRRAGDPASLIAGATHVRDLL
HCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
GWQPKHDHVEEMVKQALDWERRLHNIKGQA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVLVTGGAGYIGGHMVLGLLDAGQKVVVLDNLSTGFSWAVPQGVDLIIGDFGDQALVDR
EEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHH
VLADHHIDAIAHFGAKIVVPESVTDPLGYYLNNTAKARNLIECAAKSGVKHFIFSSTAAV
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCHHC
YGEPKANPVFEDAPLTPINPYGRSKLMVEWMLEDVAKAHALTYAILRYFNVAGADPQGRL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQASPVATHLIKIAVQAALGFRKGMDVYGTDYPTPDGSCVRDYIQVTDLVDAHLLALDYL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQGGESLTCNCGYGRGLSVLDVIRTVKAVSGVDFEVRIAGRRAGDPASLIAGATHVRDLL
HCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
GWQPKHDHVEEMVKQALDWERRLHNIKGQA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]