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The map label for this gene is yfcG [H]

Identifier: 182678794

GI number: 182678794

Start: 2074465

End: 2075088

Strand: Reverse

Name: yfcG [H]

Synonym: Bind_1824

Alternate gene names: 182678794

Gene position: 2075088-2074465 (Counterclockwise)

Preceding gene: 182678795

Following gene: 182678792

Centisome position: 49.76

GC content: 62.66

Gene sequence:

>624_bases
ATGGACGCGATCTTAGAGCTCTACGGTTCCCAGACAGGCAATTGCACGCGGTCCGCGATCGCCCTCGAGGAAGCCGGCCT
CCCTTATACGGTTCGCCTCGTGGATCTGCCGGGAGGCGAGCATCGCCGTGCCGGTCACCTCGCACTGAACCCAGCCGGTA
AGGTGCCGGTGCTGGTCGAGCACCGGCCCGGCAAACCGGATTTTGTGCTCACCCAGTCGAATGCGATCATGCTCTTCGCA
GCCGAACGAGTCCCGGGGCGGCTACTCCCTCACACTGAGCGGGCGCGCGCTACGGCATATGAGCGGTTCTTCTTTTTTCT
CACCGATGTGATTGGTCCCGCCCACGCTAGCTTCTTCCTGCAGAACCAGGGGATCGCCGACGGTGCCGCACGACTGATTG
AGCGCATGATCACGACGCTCGAGACAGCCGACCTTTATGTCGAGACCGACGAATACATGGCGGGCGACGCCTTCTCGATC
GCGGACATCGCGGCCTTTACGATCGCGGCATCGGTCGAAACGCAGGTCGCGTGGGCGCGGCTCCCCAATCTTCGCCGTTG
GTACGAAATGGTCGGATCTCGGCCATCAGTGGTCCGTGGCCAGCGAGCGTTCGATCTGAGCTGA

Upstream 100 bases:

>100_bases
TGTCGTCGCCGTTAGCAACAGCGGGATCGACATGGACTGGCATTCTGTTGCGGCTTTAGACGATTTCTTTGTGAATGAAC
ACTATCGGCAGGTGGATGCG

Downstream 100 bases:

>100_bases
CGAAATGGCAGGACCAGAGGCGGTTGCCAGGGGGCCAGCATTTGCTTCAGCTCCTTGCGGAGCTTCGTCAGTTCCGCCAT
GCCAGCCGACCGCGCTGGCA

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MDAILELYGSQTGNCTRSAIALEEAGLPYTVRLVDLPGGEHRRAGHLALNPAGKVPVLVEHRPGKPDFVLTQSNAIMLFA
AERVPGRLLPHTERARATAYERFFFFLTDVIGPAHASFFLQNQGIADGAARLIERMITTLETADLYVETDEYMAGDAFSI
ADIAAFTIAASVETQVAWARLPNLRRWYEMVGSRPSVVRGQRAFDLS

Sequences:

>Translated_207_residues
MDAILELYGSQTGNCTRSAIALEEAGLPYTVRLVDLPGGEHRRAGHLALNPAGKVPVLVEHRPGKPDFVLTQSNAIMLFA
AERVPGRLLPHTERARATAYERFFFFLTDVIGPAHASFFLQNQGIADGAARLIERMITTLETADLYVETDEYMAGDAFSI
ADIAAFTIAASVETQVAWARLPNLRRWYEMVGSRPSVVRGQRAFDLS
>Mature_207_residues
MDAILELYGSQTGNCTRSAIALEEAGLPYTVRLVDLPGGEHRRAGHLALNPAGKVPVLVEHRPGKPDFVLTQSNAIMLFA
AERVPGRLLPHTERARATAYERFFFFLTDVIGPAHASFFLQNQGIADGAARLIERMITTLETADLYVETDEYMAGDAFSI
ADIAAFTIAASVETQVAWARLPNLRRWYEMVGSRPSVVRGQRAFDLS

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=203, Percent_Identity=31.0344827586207, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI87081789, Length=205, Percent_Identity=27.3170731707317, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082195, Length=215, Percent_Identity=26.5116279069767, Blast_Score=64, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17864592, Length=189, Percent_Identity=24.8677248677249, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17864594, Length=194, Percent_Identity=26.2886597938144, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85725204, Length=178, Percent_Identity=24.1573033707865, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737923, Length=178, Percent_Identity=24.1573033707865, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19922160, Length=194, Percent_Identity=30.9278350515464, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 22778; Mature: 22778

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAILELYGSQTGNCTRSAIALEEAGLPYTVRLVDLPGGEHRRAGHLALNPAGKVPVLVE
CCHHHHHHCCCCCCCHHHHEEHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEE
HRPGKPDFVLTQSNAIMLFAAERVPGRLLPHTERARATAYERFFFFLTDVIGPAHASFFL
CCCCCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHEEEE
QNQGIADGAARLIERMITTLETADLYVETDEYMAGDAFSIADIAAFTIAASVETQVAWAR
ECCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LPNLRRWYEMVGSRPSVVRGQRAFDLS
CCCHHHHHHHHCCCCCCCCCCEECCCC
>Mature Secondary Structure
MDAILELYGSQTGNCTRSAIALEEAGLPYTVRLVDLPGGEHRRAGHLALNPAGKVPVLVE
CCHHHHHHCCCCCCCHHHHEEHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEE
HRPGKPDFVLTQSNAIMLFAAERVPGRLLPHTERARATAYERFFFFLTDVIGPAHASFFL
CCCCCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHEEEE
QNQGIADGAARLIERMITTLETADLYVETDEYMAGDAFSIADIAAFTIAASVETQVAWAR
ECCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LPNLRRWYEMVGSRPSVVRGQRAFDLS
CCCHHHHHHHHCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]