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The map label for this gene is cyaA [H]

Identifier: 182678708

GI number: 182678708

Start: 1963045

End: 1964739

Strand: Reverse

Name: cyaA [H]

Synonym: Bind_1735

Alternate gene names: 182678708

Gene position: 1964739-1963045 (Counterclockwise)

Preceding gene: 182678709

Following gene: 182678707

Centisome position: 47.11

GC content: 58.58

Gene sequence:

>1695_bases
ATGGTTCGACGGCTGCGCTTGATCACCGGTGTCATCCTCTTCACCTATGTCCTGACGCATTTTGTCAACCACAGCCTCGG
GATTATTTCGATAGCGGCGATGGACACGATGTTGTCGGTGGTGTACCCGATTTGGTCATATCCGCCGGTCACGTTCGTTC
TCTATGGCGCACTTATAATTCATGTGACGCTTGCGCTCTACGCGGTTTGGCAACGTCATTTGCTCAAGCTCCTGCCCGTC
GAGGCCGCGCAATACATTCTCGGATTCACTGTGCCCTTGCTCCTTGCGGAGCATGTGACCAACACGCGCATTGCTGCTGC
GTTCTATGGCGGGGATTTCGGTCATTACAAGAACCTGCTGACCTTCCTCTGGTACGGTCATCGCCTCAACGGTTTCTTGC
AGATAGCCTTACTGTTCGCTGCCTGGACGCATGCCTGCATCGGGTTACGATTCTCGCTGCGCTTGCGGCCATGGTATGAC
ACCGCCCAGCCATTTCTATATGCCGCGGCTCTCCTTGTGCCTGTCCTTGCGCTTTTCGGATATATCGCTGGCGGGCGAGA
GATCGGCGTGGTGATTGCGCGGGACCCTGCTTACCTGGCCCGCACGCTTGCCAGCCAGCCGCCGCCGGAAGCGCGTCCTG
CACTCTTCACCATCACTTGGAGCATTCGTTTCGTATTCCTCGGCGCCATTGCACTTGTGCTGATCGCTCGAATGGTGCGG
CATGAATGGTGGCGCCGAAAAGGTGTCGCGCGTATCTCCTATCCGGGCGGGCGTTCTATTGAGGTTGTCCGTGGCTTTAC
GGTGCTCGAGGCAAGCCGCCTCCTTGGTGTACCGCACGCCTCGATCTGTGGCGGCAAAGGACGCTGCTCGACCTGCCGCG
TGCGTGTGCGCGCCGCGCTCGGTGCGCTACCGGACCCATCTTCGGAGGAGCTCGACATCCTACATCGCATCGGCGACCCG
CCAAACGTCCGTTTAGCCTGTCAGTTGCAGCCGCTCGGACCCATCGAGGTAACGCCGCTGCTGCCGGCGTTCGAACCTGC
CCGCAAGGCTCTTCGGCATTCGATCTATGCACATGGTGGCGAACGGAGGATCGCGATCCTCTTTGCTGACCTCCGCGATT
TTACGCATATCACCGAGACTAAACTTCCTTACGACGTCGTTTTCCTGCTGAACCGTTATTGCCAGGCCATGGGCGACAGC
GTCGAAATGGCGGGTGGGCGCGTCGACAAGTTTATTGGAGATGGCGTTATGGCACTCTTCGGGTTGGAGACCGACGCTCC
GGACGCGTGCCGACAAGCCCTGATTGCGGCGCGCCTCATGTCTATCCAGCTGGTGGAGTTGAACCGGGTTCTCGCCCCCG
ATCTTGATGCTCCACTCAGATTGGGGCTTGGCATCCATTTCGGTCCGGCGATCGTCGGCGAGATAGGTAACGGAGGAATG
AAGGCGCTTACCGCGGTGGGCGATACGGTTAATACCGCAAGCCGTCTCGAGTCACTCTGCAAGCACTACGATTGCGAACT
CGTCGTCTCGGAAGATCTCATCGCATGTTCTGGTGTGGACTTACAGGGCGCACGTCGGCAGGAGGTCGAGATCCGTGGTC
ATGCCAAGCTGCTCATGATCCACACCCTGAAAAGCGCCAATCAACTGCCCTGCGAACTTGCAAGTTGCTTGGTCAGCGAG
CCAGCCCAGGAATAA

Upstream 100 bases:

>100_bases
ATTGGAAAACTGAGTCTCATGGGAGCCTGAACCTGCAACCGCATAAACGTGCGGCGGATTACGCCTTGAATTGGCGCGGT
TGACGACGCGGGAGGCACTG

Downstream 100 bases:

>100_bases
ATTCACGCGCCCTTCGGTCTAGACATTGGTCGGGAATGAAAGGGGAGGCTGCATGGATACCGGCATCGAAACCCACCCTC
TGGACTTCGGGGTCACCAAT

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MVRRLRLITGVILFTYVLTHFVNHSLGIISIAAMDTMLSVVYPIWSYPPVTFVLYGALIIHVTLALYAVWQRHLLKLLPV
EAAQYILGFTVPLLLAEHVTNTRIAAAFYGGDFGHYKNLLTFLWYGHRLNGFLQIALLFAAWTHACIGLRFSLRLRPWYD
TAQPFLYAAALLVPVLALFGYIAGGREIGVVIARDPAYLARTLASQPPPEARPALFTITWSIRFVFLGAIALVLIARMVR
HEWWRRKGVARISYPGGRSIEVVRGFTVLEASRLLGVPHASICGGKGRCSTCRVRVRAALGALPDPSSEELDILHRIGDP
PNVRLACQLQPLGPIEVTPLLPAFEPARKALRHSIYAHGGERRIAILFADLRDFTHITETKLPYDVVFLLNRYCQAMGDS
VEMAGGRVDKFIGDGVMALFGLETDAPDACRQALIAARLMSIQLVELNRVLAPDLDAPLRLGLGIHFGPAIVGEIGNGGM
KALTAVGDTVNTASRLESLCKHYDCELVVSEDLIACSGVDLQGARRQEVEIRGHAKLLMIHTLKSANQLPCELASCLVSE
PAQE

Sequences:

>Translated_564_residues
MVRRLRLITGVILFTYVLTHFVNHSLGIISIAAMDTMLSVVYPIWSYPPVTFVLYGALIIHVTLALYAVWQRHLLKLLPV
EAAQYILGFTVPLLLAEHVTNTRIAAAFYGGDFGHYKNLLTFLWYGHRLNGFLQIALLFAAWTHACIGLRFSLRLRPWYD
TAQPFLYAAALLVPVLALFGYIAGGREIGVVIARDPAYLARTLASQPPPEARPALFTITWSIRFVFLGAIALVLIARMVR
HEWWRRKGVARISYPGGRSIEVVRGFTVLEASRLLGVPHASICGGKGRCSTCRVRVRAALGALPDPSSEELDILHRIGDP
PNVRLACQLQPLGPIEVTPLLPAFEPARKALRHSIYAHGGERRIAILFADLRDFTHITETKLPYDVVFLLNRYCQAMGDS
VEMAGGRVDKFIGDGVMALFGLETDAPDACRQALIAARLMSIQLVELNRVLAPDLDAPLRLGLGIHFGPAIVGEIGNGGM
KALTAVGDTVNTASRLESLCKHYDCELVVSEDLIACSGVDLQGARRQEVEIRGHAKLLMIHTLKSANQLPCELASCLVSE
PAQE
>Mature_564_residues
MVRRLRLITGVILFTYVLTHFVNHSLGIISIAAMDTMLSVVYPIWSYPPVTFVLYGALIIHVTLALYAVWQRHLLKLLPV
EAAQYILGFTVPLLLAEHVTNTRIAAAFYGGDFGHYKNLLTFLWYGHRLNGFLQIALLFAAWTHACIGLRFSLRLRPWYD
TAQPFLYAAALLVPVLALFGYIAGGREIGVVIARDPAYLARTLASQPPPEARPALFTITWSIRFVFLGAIALVLIARMVR
HEWWRRKGVARISYPGGRSIEVVRGFTVLEASRLLGVPHASICGGKGRCSTCRVRVRAALGALPDPSSEELDILHRIGDP
PNVRLACQLQPLGPIEVTPLLPAFEPARKALRHSIYAHGGERRIAILFADLRDFTHITETKLPYDVVFLLNRYCQAMGDS
VEMAGGRVDKFIGDGVMALFGLETDAPDACRQALIAARLMSIQLVELNRVLAPDLDAPLRLGLGIHFGPAIVGEIGNGGM
KALTAVGDTVNTASRLESLCKHYDCELVVSEDLIACSGVDLQGARRQEVEIRGHAKLLMIHTLKSANQLPCELASCLVSE
PAQE

Specific function: Unknown

COG id: COG0633

COG function: function code C; Ferredoxin

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71990146, Length=150, Percent_Identity=34, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI62484477, Length=201, Percent_Identity=28.8557213930348, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI62484298, Length=201, Percent_Identity=28.8557213930348, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI116008008, Length=201, Percent_Identity=28.8557213930348, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 62044; Mature: 62044

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRLRLITGVILFTYVLTHFVNHSLGIISIAAMDTMLSVVYPIWSYPPVTFVLYGALII
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HVTLALYAVWQRHLLKLLPVEAAQYILGFTVPLLLAEHVTNTRIAAAFYGGDFGHYKNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHH
TFLWYGHRLNGFLQIALLFAAWTHACIGLRFSLRLRPWYDTAQPFLYAAALLVPVLALFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
YIAGGREIGVVIARDPAYLARTLASQPPPEARPALFTITWSIRFVFLGAIALVLIARMVR
HHCCCCEEEEEEECCHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
HEWWRRKGVARISYPGGRSIEVVRGFTVLEASRLLGVPHASICGGKGRCSTCRVRVRAAL
HHHHHHCCCEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
GALPDPSSEELDILHRIGDPPNVRLACQLQPLGPIEVTPLLPAFEPARKALRHSIYAHGG
CCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCC
ERRIAILFADLRDFTHITETKLPYDVVFLLNRYCQAMGDSVEMAGGRVDKFIGDGVMALF
CEEEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHCCCHHEEE
GLETDAPDACRQALIAARLMSIQLVELNRVLAPDLDAPLRLGLGIHFGPAIVGEIGNGGM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEECCHHHCCCCCCCH
KALTAVGDTVNTASRLESLCKHYDCELVVSEDLIACSGVDLQGARRQEVEIRGHAKLLMI
HHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCCCCCEEECCCEEEEEE
HTLKSANQLPCELASCLVSEPAQE
EECCCCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MVRRLRLITGVILFTYVLTHFVNHSLGIISIAAMDTMLSVVYPIWSYPPVTFVLYGALII
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HVTLALYAVWQRHLLKLLPVEAAQYILGFTVPLLLAEHVTNTRIAAAFYGGDFGHYKNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHH
TFLWYGHRLNGFLQIALLFAAWTHACIGLRFSLRLRPWYDTAQPFLYAAALLVPVLALFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
YIAGGREIGVVIARDPAYLARTLASQPPPEARPALFTITWSIRFVFLGAIALVLIARMVR
HHCCCCEEEEEEECCHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
HEWWRRKGVARISYPGGRSIEVVRGFTVLEASRLLGVPHASICGGKGRCSTCRVRVRAAL
HHHHHHCCCEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
GALPDPSSEELDILHRIGDPPNVRLACQLQPLGPIEVTPLLPAFEPARKALRHSIYAHGG
CCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCC
ERRIAILFADLRDFTHITETKLPYDVVFLLNRYCQAMGDSVEMAGGRVDKFIGDGVMALF
CEEEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHCCCHHEEE
GLETDAPDACRQALIAARLMSIQLVELNRVLAPDLDAPLRLGLGIHFGPAIVGEIGNGGM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEECCHHHCCCCCCCH
KALTAVGDTVNTASRLESLCKHYDCELVVSEDLIACSGVDLQGARRQEVEIRGHAKLLMI
HHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCCCCCEEECCCEEEEEE
HTLKSANQLPCELASCLVSEPAQE
EECCCCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]