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The map label for this gene is hflK [H]

Identifier: 182678703

GI number: 182678703

Start: 1956760

End: 1957929

Strand: Direct

Name: hflK [H]

Synonym: Bind_1730

Alternate gene names: 182678703

Gene position: 1956760-1957929 (Clockwise)

Preceding gene: 182678702

Following gene: 182678704

Centisome position: 46.92

GC content: 58.8

Gene sequence:

>1170_bases
ATGCCCTGGAGCAATAACGGCGGCAATGGCGAGAAGGGCATGGAGCCGAGCGGGAATCCCTGGAAATCTGGAACGGAAGG
CCCTTGGGGTCAGCGCCCGGAACCTCCGTCCAGCGATTTCGGAGATTGGCTCCGGCGCGGCCTGGACAGATTGAGGCAAC
TTCCTCCGACCGGCTGGAATATCAATATCGGCATCGGCGTTGTGCTGCTCCTCCTCTTCCTTTGGCTCGCATCCGGTTTC
TATACCGTGCGGCCCAATGAGATCGGCCTCAACAAGACATTCGGACGCTTTACCAGCAGGGCGAATCCCGGCCTCAATTA
CAACTATCCCTTCCCCATCGGCAGCGTGCAGATCCTGCAAGTGACCGATCGGAATACGATCAATATCGGCTTTACCATCC
GGCCGGATGCCCGCCATCCCAATACCCAGGCACAATATGATCTGCCCGAGGAAAGCCTGATGCTGACGGGCGATGAAAAT
ATCGCCGATGTGAAATTCGTGGTGGTCTGGCAGATCGATCCTTTGCGCCCCGAGGATTTTGCCTTCAATGTCGCCAATCA
GCGTGAAACCGTGAAAGCCGTCGCTGAAAGCGCCATGCGCGAAGTGATCGGGCGCAGCCAGATCCAGCGCATTCTGACCG
CCGAGCGCAAGGTCATCGAGCCGGCGGTGCAGGAGCTCATGCAGAAAGTCCTCAACGACTACAAAGCTGGCGTTCTCATT
TTGCAAGTACAATTGCAATCCGTCGATCCACCTGAGCAGGTGATTGCCGCCTTTCGCGATGTGACAGCGGCGCAGCAGGA
TCTCGATCGTATGCGCAACGAGGCTGAAGCCTATGCCAATCGCATCGTACCGGAAGCACGCGGCGCGGCGGCGGCAATCG
TGCAGGAAGCAGAAGGTTATCGCGCCCGTTCCATCGCCGAGGCGACTGGCCAGGCGGCGCGCTTCAACCAGATTTACGAT
GAATATAAAAAGGCTCCGCAAATCACACGCGAGCGGCTTTATCTCGAAACCCTCGAACGGGTTCTCGGCAGTGTGGACAA
GGTGCTGATCGACGCCAAGACCGGCCAGGGAGCCGTCCAGGGCGTTCTCCCCTATCTGCCGCTCGATCACTTCCAGACCG
AGACCAAGGCGCCGGAGACCCGGGCCCCCAAGGCGGGAGATCAGAAATGA

Upstream 100 bases:

>100_bases
GGCGCGACTATCCACTCATGATTGCTTGACTTACAAAACGCATCAGGAAGGATATCCGGCGATGCATGACCTCTATGCGC
AGCGAACCTGGAAAAGATGA

Downstream 100 bases:

>100_bases
AATACCCGTCCGGCCTCGCGCTTTCGCTCGTGCTGCTTGTCCTTGTCCTTCTCGGCGGTGGCACGTTCTTCATCGTGCAG
CAGACACAGCAAGCCCTGGT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MPWSNNGGNGEKGMEPSGNPWKSGTEGPWGQRPEPPSSDFGDWLRRGLDRLRQLPPTGWNINIGIGVVLLLLFLWLASGF
YTVRPNEIGLNKTFGRFTSRANPGLNYNYPFPIGSVQILQVTDRNTINIGFTIRPDARHPNTQAQYDLPEESLMLTGDEN
IADVKFVVVWQIDPLRPEDFAFNVANQRETVKAVAESAMREVIGRSQIQRILTAERKVIEPAVQELMQKVLNDYKAGVLI
LQVQLQSVDPPEQVIAAFRDVTAAQQDLDRMRNEAEAYANRIVPEARGAAAAIVQEAEGYRARSIAEATGQAARFNQIYD
EYKKAPQITRERLYLETLERVLGSVDKVLIDAKTGQGAVQGVLPYLPLDHFQTETKAPETRAPKAGDQK

Sequences:

>Translated_389_residues
MPWSNNGGNGEKGMEPSGNPWKSGTEGPWGQRPEPPSSDFGDWLRRGLDRLRQLPPTGWNINIGIGVVLLLLFLWLASGF
YTVRPNEIGLNKTFGRFTSRANPGLNYNYPFPIGSVQILQVTDRNTINIGFTIRPDARHPNTQAQYDLPEESLMLTGDEN
IADVKFVVVWQIDPLRPEDFAFNVANQRETVKAVAESAMREVIGRSQIQRILTAERKVIEPAVQELMQKVLNDYKAGVLI
LQVQLQSVDPPEQVIAAFRDVTAAQQDLDRMRNEAEAYANRIVPEARGAAAAIVQEAEGYRARSIAEATGQAARFNQIYD
EYKKAPQITRERLYLETLERVLGSVDKVLIDAKTGQGAVQGVLPYLPLDHFQTETKAPETRAPKAGDQK
>Mature_388_residues
PWSNNGGNGEKGMEPSGNPWKSGTEGPWGQRPEPPSSDFGDWLRRGLDRLRQLPPTGWNINIGIGVVLLLLFLWLASGFY
TVRPNEIGLNKTFGRFTSRANPGLNYNYPFPIGSVQILQVTDRNTINIGFTIRPDARHPNTQAQYDLPEESLMLTGDENI
ADVKFVVVWQIDPLRPEDFAFNVANQRETVKAVAESAMREVIGRSQIQRILTAERKVIEPAVQELMQKVLNDYKAGVLIL
QVQLQSVDPPEQVIAAFRDVTAAQQDLDRMRNEAEAYANRIVPEARGAAAAIVQEAEGYRARSIAEATGQAARFNQIYDE
YKKAPQITRERLYLETLERVLGSVDKVLIDAKTGQGAVQGVLPYLPLDHFQTETKAPETRAPKAGDQK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=305, Percent_Identity=36.7213114754098, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 43393; Mature: 43261

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWSNNGGNGEKGMEPSGNPWKSGTEGPWGQRPEPPSSDFGDWLRRGLDRLRQLPPTGWN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCE
INIGIGVVLLLLFLWLASGFYTVRPNEIGLNKTFGRFTSRANPGLNYNYPFPIGSVQILQ
EEHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEE
VTDRNTINIGFTIRPDARHPNTQAQYDLPEESLMLTGDENIADVKFVVVWQIDPLRPEDF
EECCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEEEEECCCCCCCC
AFNVANQRETVKAVAESAMREVIGRSQIQRILTAERKVIEPAVQELMQKVLNDYKAGVLI
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LQVQLQSVDPPEQVIAAFRDVTAAQQDLDRMRNEAEAYANRIVPEARGAAAAIVQEAEGY
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
RARSIAEATGQAARFNQIYDEYKKAPQITRERLYLETLERVLGSVDKVLIDAKTGQGAVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHH
GVLPYLPLDHFQTETKAPETRAPKAGDQK
HHHCCCCCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PWSNNGGNGEKGMEPSGNPWKSGTEGPWGQRPEPPSSDFGDWLRRGLDRLRQLPPTGWN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCE
INIGIGVVLLLLFLWLASGFYTVRPNEIGLNKTFGRFTSRANPGLNYNYPFPIGSVQILQ
EEHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEE
VTDRNTINIGFTIRPDARHPNTQAQYDLPEESLMLTGDENIADVKFVVVWQIDPLRPEDF
EECCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEEEEECCCCCCCC
AFNVANQRETVKAVAESAMREVIGRSQIQRILTAERKVIEPAVQELMQKVLNDYKAGVLI
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LQVQLQSVDPPEQVIAAFRDVTAAQQDLDRMRNEAEAYANRIVPEARGAAAAIVQEAEGY
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
RARSIAEATGQAARFNQIYDEYKKAPQITRERLYLETLERVLGSVDKVLIDAKTGQGAVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHH
GVLPYLPLDHFQTETKAPETRAPKAGDQK
HHHCCCCCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]