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The map label for this gene is ttuD [H]

Identifier: 182678694

GI number: 182678694

Start: 1945332

End: 1946675

Strand: Direct

Name: ttuD [H]

Synonym: Bind_1721

Alternate gene names: 182678694

Gene position: 1945332-1946675 (Clockwise)

Preceding gene: 182678690

Following gene: 182678695

Centisome position: 46.65

GC content: 62.2

Gene sequence:

>1344_bases
ATGCCGTTGGACGCCCCGAACAAGACTTTTGATTCGAAGGCTGATGCGCGAGCACGCCAAATTTTGCGCGAAATTTTCGA
TACCGCCGTCGCCGCGGCCGATCCCCGCAAGGTTCTTAAAAATTATCTGCCCGAGCCGCCGCGTTCAGGCCGTTGCATCG
TTGTCGGTGCCGGCAAATCCTCGGCCTTGATGGCCGCCGCATTGGAAGACGCATTGGCCGAGGCCTGGCCCACTATCTCG
CTGTCAGGTCTCGTCATCACCCGTTACGGCCATGCGGTTCCGACGCGAAAGATTGAAATCGTCGAGGCTTCGCATCCGGT
GCCGGACGCCGCCGGTGAGGCCGCCGCGCGCCGTGTGCTTGCCGCCGTTCAAGGACTGAAGCCCGATGATCTGGTCATCG
CCCTGATGTCGGGCGGCGGCTCCTCACTGCTCGCTTTACCGGCTGAGGGTCTGACGCTGGCCGATAAACAGGCGGTCAAT
CGCGCTTTGCTCGCCAGCGGCGCGACCATCGCGGAAATGAATATCGTCCGCAAACATCTCTCGGCGATCAAAGGCGGGCG
GCTCGCCGCCGCGTCAGCTCCGGCGCGGCTCGTGACTTTGGCGATCAGCGATATTCCGGGCGATGATCCGGCGGCGATCG
CCAGCGGCCCCACTTATCCCGACGCCAGCACATTTGCCGATGCCCAGGCGATCGTCGCTCGATACGGTCTCGAACTGCCC
CCCAATGTCGCCGACCATTTGCAACGTGCCGCCGACGAAACACCCAAGCCCGCCCAATTTTCCACGGTGGATTTCCGCCT
CATCGCCACACCGCTCATGGCCTTGAGCGCCTGCGCCGAAAAAGCCCGAGACCTCGGCCTCACGCCCCTCATCCTCGGCG
ATGCGCTCGAAGGAGAAGCCCGCGAAATGGGGATCATTATGGCCGGTATGGCCCGCAGCGTGGCGGCGCATGGCCTGCCG
ATCAAGGCCCCTGCCCTTTTGCTCTCGGGTGGTGAGACGACGGTGACGATCTCGAAAGGCAAGGCTGGTCGTGGTGGCCG
CAATATGGAATTTTTGCTGGCTCTCGCGGTGACTTTGCAAGGCGATGCAAACATCTGGGCTCTTGCCGGAGATACGGATG
GAATCGATGGAACGGAAGATGCCGCCGGCGCTTTCATCACGCCCAACACACTCGCGCGGGCACGGGAGGCAGGCCTCGAC
CCTTTGGCAAAGCTCCTTGAGCACGACAGCTATACCCTCTATGACCAATTGGGTGATCTGCTGCGCACCGGCCCGACGCT
GACCAATGTCAATGATCTCCGCGCCATTCTGATCGAGCCGGGCGAGACAAACGGGACTTCTTGA

Upstream 100 bases:

>100_bases
CGATCTGCGCCAAGAGAAGGCGTCGGGACAGGCTCCTGAAAGCTCATCTCACCTCCGATGTGGTTATTGAGATAAAAAAC
GAGAAGATTGGGTAGGATTC

Downstream 100 bases:

>100_bases
ACGATGAGAATTTGTTTCATCGGCGACAGTTATGTCAACGGAACAGGCGATGATGATTGCCTGGGATGGCCCGGTCGCAT
TTGCGCGGAGGCGCGGCAGC

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPLDAPNKTFDSKADARARQILREIFDTAVAAADPRKVLKNYLPEPPRSGRCIVVGAGKSSALMAAALEDALAEAWPTIS
LSGLVITRYGHAVPTRKIEIVEASHPVPDAAGEAAARRVLAAVQGLKPDDLVIALMSGGGSSLLALPAEGLTLADKQAVN
RALLASGATIAEMNIVRKHLSAIKGGRLAAASAPARLVTLAISDIPGDDPAAIASGPTYPDASTFADAQAIVARYGLELP
PNVADHLQRAADETPKPAQFSTVDFRLIATPLMALSACAEKARDLGLTPLILGDALEGEAREMGIIMAGMARSVAAHGLP
IKAPALLLSGGETTVTISKGKAGRGGRNMEFLLALAVTLQGDANIWALAGDTDGIDGTEDAAGAFITPNTLARAREAGLD
PLAKLLEHDSYTLYDQLGDLLRTGPTLTNVNDLRAILIEPGETNGTS

Sequences:

>Translated_447_residues
MPLDAPNKTFDSKADARARQILREIFDTAVAAADPRKVLKNYLPEPPRSGRCIVVGAGKSSALMAAALEDALAEAWPTIS
LSGLVITRYGHAVPTRKIEIVEASHPVPDAAGEAAARRVLAAVQGLKPDDLVIALMSGGGSSLLALPAEGLTLADKQAVN
RALLASGATIAEMNIVRKHLSAIKGGRLAAASAPARLVTLAISDIPGDDPAAIASGPTYPDASTFADAQAIVARYGLELP
PNVADHLQRAADETPKPAQFSTVDFRLIATPLMALSACAEKARDLGLTPLILGDALEGEAREMGIIMAGMARSVAAHGLP
IKAPALLLSGGETTVTISKGKAGRGGRNMEFLLALAVTLQGDANIWALAGDTDGIDGTEDAAGAFITPNTLARAREAGLD
PLAKLLEHDSYTLYDQLGDLLRTGPTLTNVNDLRAILIEPGETNGTS
>Mature_446_residues
PLDAPNKTFDSKADARARQILREIFDTAVAAADPRKVLKNYLPEPPRSGRCIVVGAGKSSALMAAALEDALAEAWPTISL
SGLVITRYGHAVPTRKIEIVEASHPVPDAAGEAAARRVLAAVQGLKPDDLVIALMSGGGSSLLALPAEGLTLADKQAVNR
ALLASGATIAEMNIVRKHLSAIKGGRLAAASAPARLVTLAISDIPGDDPAAIASGPTYPDASTFADAQAIVARYGLELPP
NVADHLQRAADETPKPAQFSTVDFRLIATPLMALSACAEKARDLGLTPLILGDALEGEAREMGIIMAGMARSVAAHGLPI
KAPALLLSGGETTVTISKGKAGRGGRNMEFLLALAVTLQGDANIWALAGDTDGIDGTEDAAGAFITPNTLARAREAGLDP
LAKLLEHDSYTLYDQLGDLLRTGPTLTNVNDLRAILIEPGETNGTS

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=487, Percent_Identity=33.264887063655, Blast_Score=188, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI193205461, Length=465, Percent_Identity=30.1075268817204, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19920578, Length=487, Percent_Identity=29.7741273100616, Blast_Score=146, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 46217; Mature: 46086

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLDAPNKTFDSKADARARQILREIFDTAVAAADPRKVLKNYLPEPPRSGRCIVVGAGKS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCCC
SALMAAALEDALAEAWPTISLSGLVITRYGHAVPTRKIEIVEASHPVPDAAGEAAARRVL
HHHHHHHHHHHHHHHCCCEEECCEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
AAVQGLKPDDLVIALMSGGGSSLLALPAEGLTLADKQAVNRALLASGATIAEMNIVRKHL
HHHHCCCCCCEEEEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHH
SAIKGGRLAAASAPARLVTLAISDIPGDDPAAIASGPTYPDASTFADAQAIVARYGLELP
HHHCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
PNVADHLQRAADETPKPAQFSTVDFRLIATPLMALSACAEKARDLGLTPLILGDALEGEA
CCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCH
REMGIIMAGMARSVAAHGLPIKAPALLLSGGETTVTISKGKAGRGGRNMEFLLALAVTLQ
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHEEEEEEEEEC
GDANIWALAGDTDGIDGTEDAAGAFITPNTLARAREAGLDPLAKLLEHDSYTLYDQLGDL
CCCCEEEEECCCCCCCCCCCCCCCEECCHHHHHHHHCCHHHHHHHHHCCCEEHHHHHHHH
LRTGPTLTNVNDLRAILIEPGETNGTS
HHCCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
PLDAPNKTFDSKADARARQILREIFDTAVAAADPRKVLKNYLPEPPRSGRCIVVGAGKS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCCC
SALMAAALEDALAEAWPTISLSGLVITRYGHAVPTRKIEIVEASHPVPDAAGEAAARRVL
HHHHHHHHHHHHHHHCCCEEECCEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
AAVQGLKPDDLVIALMSGGGSSLLALPAEGLTLADKQAVNRALLASGATIAEMNIVRKHL
HHHHCCCCCCEEEEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHH
SAIKGGRLAAASAPARLVTLAISDIPGDDPAAIASGPTYPDASTFADAQAIVARYGLELP
HHHCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
PNVADHLQRAADETPKPAQFSTVDFRLIATPLMALSACAEKARDLGLTPLILGDALEGEA
CCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCH
REMGIIMAGMARSVAAHGLPIKAPALLLSGGETTVTISKGKAGRGGRNMEFLLALAVTLQ
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHEEEEEEEEEC
GDANIWALAGDTDGIDGTEDAAGAFITPNTLARAREAGLDPLAKLLEHDSYTLYDQLGDL
CCCCEEEEECCCCCCCCCCCCCCCEECCHHHHHHHHCCHHHHHHHHHCCCEEHHHHHHHH
LRTGPTLTNVNDLRAILIEPGETNGTS
HHCCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]