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The map label for this gene is minD [H]

Identifier: 182678676

GI number: 182678676

Start: 1924150

End: 1924968

Strand: Reverse

Name: minD [H]

Synonym: Bind_1703

Alternate gene names: 182678676

Gene position: 1924968-1924150 (Counterclockwise)

Preceding gene: 182678677

Following gene: 182678675

Centisome position: 46.16

GC content: 61.05

Gene sequence:

>819_bases
ATGGCCAAGGTTTTGGTCGTGACGTCCGGCAAGGGCGGAGTAGGCAAAACGACGTCGAGCGCGGCCCTGGGCACAGCGCT
CGCGCAAATGGGTCAAAGGGTGGTCGTCGTCGATTTCGACGTCGGATTGCGTAATCTTGATCTGGTGATGGGCGCTGAGC
GCCGCGTGGTCTTCGATCTCATCAATGTCGTGCAGGGCGAGGCCAAGCTCGCTCAAGCCCTGATCCGCGACAAGAGGTTG
GATAATCTTTCGTTGCTTCCGGCTTCGCAGACACGCGACAAGGAAGCCTTGACGGAAGAGGGGGTTGGCCGGGTCATCGC
CGAGTTGAAGGAAAAGTTCGACTGGGTGGTCTGCGATAGCCCCGCCGGGATCGAACGCGGGGCGACCCTCGCCATGCGTT
ACGCCGATCTCGCCGTGGTCGTCGCCAATCCCGAAGTCTCTTCCGTTCGCGATTCCGACCGGATCATCGGATTGCTCGAT
TCAAAAACGCTCAAGGCCGAAAAGGGCGAGCCGCTTGAAAAGCATCTCCTCTTGACCCGTTATGACGCCATGCGGGCAGA
GCGTCGCGAAATGCTGGCTGTCGAGGATGTTCTCGAAATCCTTTCCATCCCGCTGCTCGGCATTATTCCCGAAAGCGAGG
AGGTTCTGCGGGCGTCCAATGTTGGCGCGCCGGTCACGCTCAACAATCCCGGTTGCGCCCCCTCGCGGGCCTATCAGGAC
GCGGCGCGGCGCTTGACCGGAGAGATGGTCACCATGTCGGTGCCCCGTGATAAAAAGGGCAGCCTCCTCGGCAAGCTGTT
CGGACGGAGGGCCGCATGA

Upstream 100 bases:

>100_bases
GAGGACGGCCGGCGTCAGGAAGGTCCGCTTCTCTTGATTTTAACGTGTGGTTTTCAGCAAGTCCTGTGACTTTCTGAAAG
TGGCTCTAGGGGAGGCCAGA

Downstream 100 bases:

>100_bases
GTCTGTTCGATTTCTTCAGGCGCCCAACGTCGGCGCCCGTCGCCCGTGAGCGGCTGCAAATCCTGCTCGCCCATGAGCGC
GCGGTCATTGGCCGTTCCGA

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MAKVLVVTSGKGGVGKTTSSAALGTALAQMGQRVVVVDFDVGLRNLDLVMGAERRVVFDLINVVQGEAKLAQALIRDKRL
DNLSLLPASQTRDKEALTEEGVGRVIAELKEKFDWVVCDSPAGIERGATLAMRYADLAVVVANPEVSSVRDSDRIIGLLD
SKTLKAEKGEPLEKHLLLTRYDAMRAERREMLAVEDVLEILSIPLLGIIPESEEVLRASNVGAPVTLNNPGCAPSRAYQD
AARRLTGEMVTMSVPRDKKGSLLGKLFGRRAA

Sequences:

>Translated_272_residues
MAKVLVVTSGKGGVGKTTSSAALGTALAQMGQRVVVVDFDVGLRNLDLVMGAERRVVFDLINVVQGEAKLAQALIRDKRL
DNLSLLPASQTRDKEALTEEGVGRVIAELKEKFDWVVCDSPAGIERGATLAMRYADLAVVVANPEVSSVRDSDRIIGLLD
SKTLKAEKGEPLEKHLLLTRYDAMRAERREMLAVEDVLEILSIPLLGIIPESEEVLRASNVGAPVTLNNPGCAPSRAYQD
AARRLTGEMVTMSVPRDKKGSLLGKLFGRRAA
>Mature_271_residues
AKVLVVTSGKGGVGKTTSSAALGTALAQMGQRVVVVDFDVGLRNLDLVMGAERRVVFDLINVVQGEAKLAQALIRDKRLD
NLSLLPASQTRDKEALTEEGVGRVIAELKEKFDWVVCDSPAGIERGATLAMRYADLAVVVANPEVSSVRDSDRIIGLLDS
KTLKAEKGEPLEKHLLLTRYDAMRAERREMLAVEDVLEILSIPLLGIIPESEEVLRASNVGAPVTLNNPGCAPSRAYQDA
ARRLTGEMVTMSVPRDKKGSLLGKLFGRRAA

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=270, Percent_Identity=60, Blast_Score=321, Evalue=3e-89,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29328; Mature: 29197

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLVVTSGKGGVGKTTSSAALGTALAQMGQRVVVVDFDVGLRNLDLVMGAERRVVFDL
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHEEECCCHHHHHHH
INVVQGEAKLAQALIRDKRLDNLSLLPASQTRDKEALTEEGVGRVIAELKEKFDWVVCDS
HHHHCCHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECC
PAGIERGATLAMRYADLAVVVANPEVSSVRDSDRIIGLLDSKTLKAEKGEPLEKHLLLTR
CCCCCCCCHHEEEEEEEEEEEECCCHHHCCCCCCEEEEECCCEECCCCCCCHHHHHHHHH
YDAMRAERREMLAVEDVLEILSIPLLGIIPESEEVLRASNVGAPVTLNNPGCAPSRAYQD
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCCEEECCCCCCCHHHHHH
AARRLTGEMVTMSVPRDKKGSLLGKLFGRRAA
HHHHHCCCEEEEECCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
AKVLVVTSGKGGVGKTTSSAALGTALAQMGQRVVVVDFDVGLRNLDLVMGAERRVVFDL
CEEEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHEEECCCHHHHHHH
INVVQGEAKLAQALIRDKRLDNLSLLPASQTRDKEALTEEGVGRVIAELKEKFDWVVCDS
HHHHCCHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECC
PAGIERGATLAMRYADLAVVVANPEVSSVRDSDRIIGLLDSKTLKAEKGEPLEKHLLLTR
CCCCCCCCHHEEEEEEEEEEEECCCHHHCCCCCCEEEEECCCEECCCCCCCHHHHHHHHH
YDAMRAERREMLAVEDVLEILSIPLLGIIPESEEVLRASNVGAPVTLNNPGCAPSRAYQD
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCCEEECCCCCCCHHHHHH
AARRLTGEMVTMSVPRDKKGSLLGKLFGRRAA
HHHHHCCCEEEEECCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]