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The map label for this gene is aroA [H]

Identifier: 182678604

GI number: 182678604

Start: 1840688

End: 1841962

Strand: Reverse

Name: aroA [H]

Synonym: Bind_1630

Alternate gene names: 182678604

Gene position: 1841962-1840688 (Counterclockwise)

Preceding gene: 182678609

Following gene: 182678600

Centisome position: 44.17

GC content: 58.59

Gene sequence:

>1275_bases
ATGATACCCAATCACAAAGTGAAAGACGCCCTTCGTCTTTCGCCTCCCGGCCAGCCACTGCAGGGTCATATCAGACCGCC
AGGATCCAAATCGATCACCAATCGGGCTTTGCTGCTCGCGGCCCTCGCCAAGGGTGAAAGCCGGCTGACGGGGGCCTTGG
CGAGTGATGACACAGCCTATATGGCCAAAGCGCTCAAGGCGATGGGCGTCGGGATCGAAAGCCCCGATGCGACCACCTTT
CACGTCAAGGGAACTGGCCATCTGCATGCGCCGGGTGAAACGCTCTTTCTCGGCAATGCCGGGACGGCGACACGTTTTCT
GACGGCGGCAGCGGCATTGGCCGATGGTCGCGTGGTCATCGATGGCGATGCCAATATGCGCAAACGCCCGATCGCTCCTC
TTGTCACCGCCTTGCAAAGCCTTGGTGTCTCCATCGAGGCTCCGACTGGATGCCCTCCTGTCACGATCGATGGCCGAGGC
CGTGTCGCGGCAGGCGACGTTTCGATCGATGCTGGTCTTTCCAGTCAATATGTTTCGGCGCTTTTGATGCTGGCCCCATG
CGGCGAGGGACCAATCAGGATTGTCTTGCAAGGCACGGGCATAGGCGCGCGTGGTTATGTCGATCTCACGCTCGCCGCCA
TGCACCATTTTGGCGCCGAGGTTTTACAAAAAGACGAAGTGTCCTGGACGCTTGCGCCAACAGGGTATCGCGCGCGCGAT
TTCGTCATTGAGCCCGATGCTTCGGCGGCCACTTATCTCTGGGCCGCCGCCGTTTTGACCCAGGGAACCATCGATCTCGG
TGTGCCAGCCTCCGCCTTCACACAGCCGGATGCCAAGGCCTATTCTCTGATCACATCATTCCCTCATATGCCGGCCGTGA
TCGAGGGATCACAGATCCAGGATGCCGTGCCGACTCTCGCGGTCATGGCGGCATTCAATAAAACGCCCGTGCGTTTCACG
GATATTGCCAATCTCAGAGTCAAGGAATGCGACCGCATTCATGCGCTGGCGACAGAACTCGCACGCATCACCCCGGATTT
AGCACGCGAGGAGGGTGATGATCTGATCGTCACCGGCGATCCCGCACTCATTGGACGGCGAACCGACGCTATCATTGAAA
CCTATGATGATCATCGGATTGCCATGAGTTTCGCGCTGGCGGGCCTGATGATGGACGGACTGACAATCCTCGATCCCGAC
TGTGTAGCCAAAACCTATCCGGGGTTTTGGAACGATCTCGGCTCGCTGGGTGTCAGGCTTGAGAGGATTACATGA

Upstream 100 bases:

>100_bases
CAGAACGGGATCAAGCGTTAAATCAAAATGATGCTGGGCATTGAACCCGAATGGTACCCTATGTGCGGGCTGAACGGCCC
CCAATCCAAGAGCTCTATGG

Downstream 100 bases:

>100_bases
TCATTTACATCTACCATTACGCCTTTGACCGAAACGAAAGAGTCCATAGTTGGCTTTTTGTTTTGGCCTCCGCATGGCAT
TGTGCTGCGAAAGCGCGATA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MIPNHKVKDALRLSPPGQPLQGHIRPPGSKSITNRALLLAALAKGESRLTGALASDDTAYMAKALKAMGVGIESPDATTF
HVKGTGHLHAPGETLFLGNAGTATRFLTAAAALADGRVVIDGDANMRKRPIAPLVTALQSLGVSIEAPTGCPPVTIDGRG
RVAAGDVSIDAGLSSQYVSALLMLAPCGEGPIRIVLQGTGIGARGYVDLTLAAMHHFGAEVLQKDEVSWTLAPTGYRARD
FVIEPDASAATYLWAAAVLTQGTIDLGVPASAFTQPDAKAYSLITSFPHMPAVIEGSQIQDAVPTLAVMAAFNKTPVRFT
DIANLRVKECDRIHALATELARITPDLAREEGDDLIVTGDPALIGRRTDAIIETYDDHRIAMSFALAGLMMDGLTILDPD
CVAKTYPGFWNDLGSLGVRLERIT

Sequences:

>Translated_424_residues
MIPNHKVKDALRLSPPGQPLQGHIRPPGSKSITNRALLLAALAKGESRLTGALASDDTAYMAKALKAMGVGIESPDATTF
HVKGTGHLHAPGETLFLGNAGTATRFLTAAAALADGRVVIDGDANMRKRPIAPLVTALQSLGVSIEAPTGCPPVTIDGRG
RVAAGDVSIDAGLSSQYVSALLMLAPCGEGPIRIVLQGTGIGARGYVDLTLAAMHHFGAEVLQKDEVSWTLAPTGYRARD
FVIEPDASAATYLWAAAVLTQGTIDLGVPASAFTQPDAKAYSLITSFPHMPAVIEGSQIQDAVPTLAVMAAFNKTPVRFT
DIANLRVKECDRIHALATELARITPDLAREEGDDLIVTGDPALIGRRTDAIIETYDDHRIAMSFALAGLMMDGLTILDPD
CVAKTYPGFWNDLGSLGVRLERIT
>Mature_424_residues
MIPNHKVKDALRLSPPGQPLQGHIRPPGSKSITNRALLLAALAKGESRLTGALASDDTAYMAKALKAMGVGIESPDATTF
HVKGTGHLHAPGETLFLGNAGTATRFLTAAAALADGRVVIDGDANMRKRPIAPLVTALQSLGVSIEAPTGCPPVTIDGRG
RVAAGDVSIDAGLSSQYVSALLMLAPCGEGPIRIVLQGTGIGARGYVDLTLAAMHHFGAEVLQKDEVSWTLAPTGYRARD
FVIEPDASAATYLWAAAVLTQGTIDLGVPASAFTQPDAKAYSLITSFPHMPAVIEGSQIQDAVPTLAVMAAFNKTPVRFT
DIANLRVKECDRIHALATELARITPDLAREEGDDLIVTGDPALIGRRTDAIIETYDDHRIAMSFALAGLMMDGLTILDPD
CVAKTYPGFWNDLGSLGVRLERIT

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=431, Percent_Identity=36.6589327146172, Blast_Score=202, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6320332, Length=469, Percent_Identity=36.6737739872068, Blast_Score=208, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 44599; Mature: 44599

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPNHKVKDALRLSPPGQPLQGHIRPPGSKSITNRALLLAALAKGESRLTGALASDDTAY
CCCCCCCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHH
MAKALKAMGVGIESPDATTFHVKGTGHLHAPGETLFLGNAGTATRFLTAAAALADGRVVI
HHHHHHHHCCCCCCCCCEEEEEECCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
DGDANMRKRPIAPLVTALQSLGVSIEAPTGCPPVTIDGRGRVAAGDVSIDAGLSSQYVSA
ECCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCEEECCCCCEEECCEEECCCCCHHHHHH
LLMLAPCGEGPIRIVLQGTGIGARGYVDLTLAAMHHFGAEVLQKDEVSWTLAPTGYRARD
HHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEE
FVIEPDASAATYLWAAAVLTQGTIDLGVPASAFTQPDAKAYSLITSFPHMPAVIEGSQIQ
EEECCCCCHHHHHHHHHHHHCCCEECCCCHHHCCCCCHHHHHHHHCCCCCCEEEECCCHH
DAVPTLAVMAAFNKTPVRFTDIANLRVKECDRIHALATELARITPDLAREEGDDLIVTGD
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEECC
PALIGRRTDAIIETYDDHRIAMSFALAGLMMDGLTILDPDCVAKTYPGFWNDLGSLGVRL
CCEECCCCHHHEEECCCCHHHHHHHHHHHHHCCCEEECCHHHHHCCCCHHHHHHHHCEEE
ERIT
EECC
>Mature Secondary Structure
MIPNHKVKDALRLSPPGQPLQGHIRPPGSKSITNRALLLAALAKGESRLTGALASDDTAY
CCCCCCCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHH
MAKALKAMGVGIESPDATTFHVKGTGHLHAPGETLFLGNAGTATRFLTAAAALADGRVVI
HHHHHHHHCCCCCCCCCEEEEEECCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
DGDANMRKRPIAPLVTALQSLGVSIEAPTGCPPVTIDGRGRVAAGDVSIDAGLSSQYVSA
ECCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCEEECCCCCEEECCEEECCCCCHHHHHH
LLMLAPCGEGPIRIVLQGTGIGARGYVDLTLAAMHHFGAEVLQKDEVSWTLAPTGYRARD
HHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEE
FVIEPDASAATYLWAAAVLTQGTIDLGVPASAFTQPDAKAYSLITSFPHMPAVIEGSQIQ
EEECCCCCHHHHHHHHHHHHCCCEECCCCHHHCCCCCHHHHHHHHCCCCCCEEEECCCHH
DAVPTLAVMAAFNKTPVRFTDIANLRVKECDRIHALATELARITPDLAREEGDDLIVTGD
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEECC
PALIGRRTDAIIETYDDHRIAMSFALAGLMMDGLTILDPDCVAKTYPGFWNDLGSLGVRL
CCEECCCCHHHEEECCCCHHHHHHHHHHHHHCCCEEECCHHHHHCCCCHHHHHHHHCEEE
ERIT
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA