Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 182678461

GI number: 182678461

Start: 1688964

End: 1689908

Strand: Direct

Name: nahR [H]

Synonym: Bind_1485

Alternate gene names: 182678461

Gene position: 1688964-1689908 (Clockwise)

Preceding gene: 182678459

Following gene: 182678463

Centisome position: 40.5

GC content: 64.87

Gene sequence:

>945_bases
ATGAAATGCATTATTGCTATAATGAACATAACACAAAAGCATCTTCCGGGAATCGACCTTGATCTGCTGCCGGTGCTCGA
CGCGCTGCTGCGGCGGCGCAATGTCACCCATGCCGGACGGGAGGTTGGGCTGAGCCAGCCGGCGATGAGTCGCGCGCTCG
GCCGGCTGCGGCATCTGTTCGATGATCCGCTGCTGGTGCGCCAGGCGGGCGGCTTCGCGCTGACGCCCAAGGCGCAGCGG
CTGGCGCCACAGGTCGCTATCGCGCTCGAACAGGTGGGCGCGCTGTTCCGCGATGCGCCGTTTGATCCCGCGGCGGAGCA
GCGCACGATCCGCATCGTCGCGGCCGATGCCCAAACGCTGCTGCTGTTGCCCGAGGTCATGCGTCGGGTCTCCCGCGAGG
CGCCGGGGATACGCGTCGCCGTGGAGGGCTATAGTCCCGAAACGATCACCCATATGCAGCAGGGACGGATCGATTTCGCC
TTCGCGCTGGCGTCCTCTCCGCTGCCACCGGGAGCGGAGAGCATGACACTGGGCACCGACCGGCTGATGCTGGTGACGCG
GCGCGATCATCCGCTGGCGGCAGGGCCGGTATCGGCGGAAGACTATGCGCGCTTTCCCCACGTGGCGATCACCATCTTTG
GCGATGGCCAGTCGGAGATCGATGCGGCGCTGGCGGCGCGGCGGCTGTCGCGCACGATCGCGCTGACTACGCCGTATTTC
GCCGCCGCTTTGGCTGTTGTGGCGGCGACGGATTACGTGACCACGCTATCGGAGGCGCTGGCCCGCCGTTTCAGCGACAC
GTTCAGCCTGGTGATCAGGCCATCGCCGCTGATCGCAGAACCCCATTCCCTCACATTGGTTTGGGACCGTATCCGCTCCA
AAGATCCGGCTCTTTTCTGGTTCCGTGAATTGGTGCGCGACGTGGCGGTAACGATCTACGGATAA

Upstream 100 bases:

>100_bases
CGCGGCCGGCCACGCCATAGCCGAAGATCACATCAAGTCCGTTCATCCTGCGCCCTCTCGTTGTCGATCTTGCGCAAGAT
AGCACTGGACCCAGTCATGC

Downstream 100 bases:

>100_bases
GGCGGTGACAGACGCTCCCTCTGAGGCAACCTCTGCTCCTCCCGCAAGCTTCAGCCTTCGGCAATGTGCAACCGTTCGAG
ATCGGCGATCAGGCTGGGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKCIIAIMNITQKHLPGIDLDLLPVLDALLRRRNVTHAGREVGLSQPAMSRALGRLRHLFDDPLLVRQAGGFALTPKAQR
LAPQVAIALEQVGALFRDAPFDPAAEQRTIRIVAADAQTLLLLPEVMRRVSREAPGIRVAVEGYSPETITHMQQGRIDFA
FALASSPLPPGAESMTLGTDRLMLVTRRDHPLAAGPVSAEDYARFPHVAITIFGDGQSEIDAALAARRLSRTIALTTPYF
AAALAVVAATDYVTTLSEALARRFSDTFSLVIRPSPLIAEPHSLTLVWDRIRSKDPALFWFRELVRDVAVTIYG

Sequences:

>Translated_314_residues
MKCIIAIMNITQKHLPGIDLDLLPVLDALLRRRNVTHAGREVGLSQPAMSRALGRLRHLFDDPLLVRQAGGFALTPKAQR
LAPQVAIALEQVGALFRDAPFDPAAEQRTIRIVAADAQTLLLLPEVMRRVSREAPGIRVAVEGYSPETITHMQQGRIDFA
FALASSPLPPGAESMTLGTDRLMLVTRRDHPLAAGPVSAEDYARFPHVAITIFGDGQSEIDAALAARRLSRTIALTTPYF
AAALAVVAATDYVTTLSEALARRFSDTFSLVIRPSPLIAEPHSLTLVWDRIRSKDPALFWFRELVRDVAVTIYG
>Mature_314_residues
MKCIIAIMNITQKHLPGIDLDLLPVLDALLRRRNVTHAGREVGLSQPAMSRALGRLRHLFDDPLLVRQAGGFALTPKAQR
LAPQVAIALEQVGALFRDAPFDPAAEQRTIRIVAADAQTLLLLPEVMRRVSREAPGIRVAVEGYSPETITHMQQGRIDFA
FALASSPLPPGAESMTLGTDRLMLVTRRDHPLAAGPVSAEDYARFPHVAITIFGDGQSEIDAALAARRLSRTIALTTPYF
AAALAVVAATDYVTTLSEALARRFSDTFSLVIRPSPLIAEPHSLTLVWDRIRSKDPALFWFRELVRDVAVTIYG

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=298, Percent_Identity=26.510067114094, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790147, Length=304, Percent_Identity=23.3552631578947, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081766, Length=298, Percent_Identity=23.8255033557047, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34366; Mature: 34366

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCIIAIMNITQKHLPGIDLDLLPVLDALLRRRNVTHAGREVGLSQPAMSRALGRLRHLF
CCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
DDPLLVRQAGGFALTPKAQRLAPQVAIALEQVGALFRDAPFDPAAEQRTIRIVAADAQTL
CCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHHH
LLLPEVMRRVSREAPGIRVAVEGYSPETITHMQQGRIDFAFALASSPLPPGAESMTLGTD
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCC
RLMLVTRRDHPLAAGPVSAEDYARFPHVAITIFGDGQSEIDAALAARRLSRTIALTTPYF
EEEEEEECCCCCCCCCCCHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHEEEEECHHH
AAALAVVAATDYVTTLSEALARRFSDTFSLVIRPSPLIAEPHSLTLVWDRIRSKDPALFW
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEHHHCCCCCHHHH
FRELVRDVAVTIYG
HHHHHHHHHEEECC
>Mature Secondary Structure
MKCIIAIMNITQKHLPGIDLDLLPVLDALLRRRNVTHAGREVGLSQPAMSRALGRLRHLF
CCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
DDPLLVRQAGGFALTPKAQRLAPQVAIALEQVGALFRDAPFDPAAEQRTIRIVAADAQTL
CCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHHH
LLLPEVMRRVSREAPGIRVAVEGYSPETITHMQQGRIDFAFALASSPLPPGAESMTLGTD
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCC
RLMLVTRRDHPLAAGPVSAEDYARFPHVAITIFGDGQSEIDAALAARRLSRTIALTTPYF
EEEEEEECCCCCCCCCCCHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHEEEEECHHH
AAALAVVAATDYVTTLSEALARRFSDTFSLVIRPSPLIAEPHSLTLVWDRIRSKDPALFW
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEHHHCCCCCHHHH
FRELVRDVAVTIYG
HHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]