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The map label for this gene is tpiA [H]

Identifier: 182678432

GI number: 182678432

Start: 1659311

End: 1660069

Strand: Direct

Name: tpiA [H]

Synonym: Bind_1450

Alternate gene names: 182678432

Gene position: 1659311-1660069 (Clockwise)

Preceding gene: 182678428

Following gene: 182678433

Centisome position: 39.79

GC content: 60.61

Gene sequence:

>759_bases
ATGACCAAAACATTACGCCCGCTTATCGCGGGAAATTGGAAGATGAATGGCCTGCGCAAGGATCTCGACGAAATTGCCGC
TATCCGGGATGGCGGCGTGAAAGTGGGGGGAGCGGTGGAGATCGTGGTCTGCCCTCCATTCACCTTACTTGCGGCGGCTG
CCAGCCTTTGCGAAGGCTCCGGGATCGGCATCGGCGGACAGGACTGCCATCCGGAGAAAAAGGGCGCCTTCACGGGGGAT
ATCGCGCCGCCCATGCTCAAGGATTGCGGCGCCACTTACGTGATTCTGGGCCATTCCGAACGCCGTCTCATCCATGGCGA
ATCCGATGCCTTGATTCGTGACAAGATCAAGGGGGTACAAGCGGCTGGGCTCGCGGCGATCTTGTGCGTCGGCGAAACAG
CGGAGCAAAGGAGTACCGGCCAGGCGCTTGCGGTCGTTGGCGAACAATTGGCGGGATCGATCCCGCGTGATGTTTCGATC
GAGGGCCTGGTCATCGCCTATGAACCGGTCTGGGCCATCGGCACCGGTTTGACGCCGACCGCGGAGGATATAGCCGAAAT
GCATGGCTTCATCCGTGCGAAACTCGAAGAAAGCTGGCCGGGCAAGGCCGCAACAGTGCGGTTGCTCTATGGTGGCTCCG
TCAAACCGAGCAATGCCGCCAAATTGCTCGCCATCGCCAATGTCGATGGCGCGTTGATCGGTGGCGCCAGTCTTATTGCG
GCGGATTTTCTGGCGATCGCGGCGGCCTGTCCCGTGTGA

Upstream 100 bases:

>100_bases
AGCGGCGGGGTCCCCCGCAACGGGGCAGTTGCACCGTCATGCAGGCGTGCTACCAAACGAGACCGGGAAACCTGATGAAA
AGATCGATGAAAGGCCGCTC

Downstream 100 bases:

>100_bases
TGAAAGAGTCCGCAACATAAATTTTTTATTCTTTCTCGACCTTCCCCTAGCCAGAGGAAGGCACGCGGTATAGATCATGC
CGCAGATGAAAGTCTGCGGC

Product: Triose-phosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTKTLRPLIAGNWKMNGLRKDLDEIAAIRDGGVKVGGAVEIVVCPPFTLLAAAASLCEGSGIGIGGQDCHPEKKGAFTGD
IAPPMLKDCGATYVILGHSERRLIHGESDALIRDKIKGVQAAGLAAILCVGETAEQRSTGQALAVVGEQLAGSIPRDVSI
EGLVIAYEPVWAIGTGLTPTAEDIAEMHGFIRAKLEESWPGKAATVRLLYGGSVKPSNAAKLLAIANVDGALIGGASLIA
ADFLAIAAACPV

Sequences:

>Translated_252_residues
MTKTLRPLIAGNWKMNGLRKDLDEIAAIRDGGVKVGGAVEIVVCPPFTLLAAAASLCEGSGIGIGGQDCHPEKKGAFTGD
IAPPMLKDCGATYVILGHSERRLIHGESDALIRDKIKGVQAAGLAAILCVGETAEQRSTGQALAVVGEQLAGSIPRDVSI
EGLVIAYEPVWAIGTGLTPTAEDIAEMHGFIRAKLEESWPGKAATVRLLYGGSVKPSNAAKLLAIANVDGALIGGASLIA
ADFLAIAAACPV
>Mature_251_residues
TKTLRPLIAGNWKMNGLRKDLDEIAAIRDGGVKVGGAVEIVVCPPFTLLAAAASLCEGSGIGIGGQDCHPEKKGAFTGDI
APPMLKDCGATYVILGHSERRLIHGESDALIRDKIKGVQAAGLAAILCVGETAEQRSTGQALAVVGEQLAGSIPRDVSIE
GLVIAYEPVWAIGTGLTPTAEDIAEMHGFIRAKLEESWPGKAATVRLLYGGSVKPSNAAKLLAIANVDGALIGGASLIAA
DFLAIAAACPV

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI226529917, Length=239, Percent_Identity=40.5857740585774, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI4507645, Length=239, Percent_Identity=40.5857740585774, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI1790353, Length=247, Percent_Identity=42.1052631578947, Blast_Score=179, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17536593, Length=247, Percent_Identity=44.9392712550607, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320255, Length=239, Percent_Identity=42.6778242677824, Blast_Score=183, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28572004, Length=232, Percent_Identity=44.8275862068966, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI28572008, Length=232, Percent_Identity=44.8275862068966, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI28572006, Length=232, Percent_Identity=44.8275862068966, Blast_Score=187, Evalue=5e-48,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25827; Mature: 25696

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00099 THIOLASE_3 ; PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTLRPLIAGNWKMNGLRKDLDEIAAIRDGGVKVGGAVEIVVCPPFTLLAAAASLCEGS
CCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCEEEEEECCCHHHHHHHHHHHCCC
GIGIGGQDCHPEKKGAFTGDIAPPMLKDCGATYVILGHSERRLIHGESDALIRDKIKGVQ
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCEEEECCCCHHHHHHHCCCH
AAGLAAILCVGETAEQRSTGQALAVVGEQLAGSIPRDVSIEGLVIAYEPVWAIGTGLTPT
HCCEEEEEEECCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEECCCCCCC
AEDIAEMHGFIRAKLEESWPGKAATVRLLYGGSVKPSNAAKLLAIANVDGALIGGASLIA
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEECCHHHHH
ADFLAIAAACPV
HHHHHHHHCCCC
>Mature Secondary Structure 
TKTLRPLIAGNWKMNGLRKDLDEIAAIRDGGVKVGGAVEIVVCPPFTLLAAAASLCEGS
CCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCEEEEEECCCHHHHHHHHHHHCCC
GIGIGGQDCHPEKKGAFTGDIAPPMLKDCGATYVILGHSERRLIHGESDALIRDKIKGVQ
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCEEEECCCCHHHHHHHCCCH
AAGLAAILCVGETAEQRSTGQALAVVGEQLAGSIPRDVSIEGLVIAYEPVWAIGTGLTPT
HCCEEEEEEECCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEECCCCCCC
AEDIAEMHGFIRAKLEESWPGKAATVRLLYGGSVKPSNAAKLLAIANVDGALIGGASLIA
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEECCHHHHH
ADFLAIAAACPV
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA