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The map label for this gene is yafC [H]

Identifier: 182678391

GI number: 182678391

Start: 1619533

End: 1620465

Strand: Direct

Name: yafC [H]

Synonym: Bind_1408

Alternate gene names: 182678391

Gene position: 1619533-1620465 (Clockwise)

Preceding gene: 182678389

Following gene: 182678394

Centisome position: 38.84

GC content: 64.09

Gene sequence:

>933_bases
ATGGATAAATTGGACGTCACACTTGAGCGCATACGCACCTTCGTCCGCGTCGCCGAGCGCGGGAGCCTGTCGGCGGTCGC
GCGGGAGCAGGAGGTCGGTCAGTCGACCGTCACCCGGCATTTGCGAGAACTCGAGGAAGCTGTCGGCGTGCCCTTGCTCA
GCAGGACGACCCGGCGTGTCACGCTGACCGATGAAGGCAGCCGCTATTATGCCAATAGCGTCCAGATCCTGCGCCTCGTG
GAGCAGGCCGGCGATGAGGCACGAGGCACGCGCGGTGCGCCAGCCGGCACGATCCGGATATCCTGCACCGCGGCTTTCGG
GGTTTTGCACGTCAGCCGGATGATCTTTGCCTTCCAGGATCGCTATCCCAATATCGGGGTCGACCTCAGCCTGACCGACG
AACGTGTCGACCTTGTCCGTGAGGGCGTCGATATTGCGCTTCGCCTGGGTCCGCTCACCGACAGTTCCATGAAGCTACGA
TCCCTCGGACAGAGCCGGCGCCTGCTGGTGGCAGCACCGTCCTATCTGGCTGCACGGGGAACGCCGGCTGTCCCGCAGGA
CCTGTCTGCTCATGAAGGCATTCGGATGTCGCATGTGGCGGGAAGCGACACCCTCATCTTGCAGGGGCCGGGCGGTGAGC
GCCATGCTGTGCCTTTTGGAGGGCGTTTTCGGATTGACCATGGGCTTGCCGCCCGCGAGGCCTTTGTCGCAGGGCGCGGC
ATTGGACCCGCCCATCGATGGCTTGTCGATGATCTCCTGCAAACGAGCCGGCTCCAGGAGATCCTGCCCGATTATTCGCT
ACCACCCGCCCCGCTGAGCATGCTGATTGTTCCGGAGCGCGCGGGCATTGCCCGGGTCCGGCTGGTGGCTGATTTCCTTG
CGGAGCAGATTAGCGGCGTTCCGGGGATTGAGAAGCCTCGGCCAGAGCGTTAG

Upstream 100 bases:

>100_bases
TCATGAGGTCAGCGATCCGGGATTGGGAAAGGGACCTGCACGGTAGATGACGCCGGAGCAATCCACTATAGTTGGTTAAT
GGATAGGATTATGCCGAATA

Downstream 100 bases:

>100_bases
CTGACGAGCTTCACTTCCATGCCGATGCGGCTCTTGAGTGACGCCTCATGCAAAGGGGCTGACGAACATTGGTTCGCCAG
CCCCTTGTTGGATGTGCGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDKLDVTLERIRTFVRVAERGSLSAVAREQEVGQSTVTRHLRELEEAVGVPLLSRTTRRVTLTDEGSRYYANSVQILRLV
EQAGDEARGTRGAPAGTIRISCTAAFGVLHVSRMIFAFQDRYPNIGVDLSLTDERVDLVREGVDIALRLGPLTDSSMKLR
SLGQSRRLLVAAPSYLAARGTPAVPQDLSAHEGIRMSHVAGSDTLILQGPGGERHAVPFGGRFRIDHGLAAREAFVAGRG
IGPAHRWLVDDLLQTSRLQEILPDYSLPPAPLSMLIVPERAGIARVRLVADFLAEQISGVPGIEKPRPER

Sequences:

>Translated_310_residues
MDKLDVTLERIRTFVRVAERGSLSAVAREQEVGQSTVTRHLRELEEAVGVPLLSRTTRRVTLTDEGSRYYANSVQILRLV
EQAGDEARGTRGAPAGTIRISCTAAFGVLHVSRMIFAFQDRYPNIGVDLSLTDERVDLVREGVDIALRLGPLTDSSMKLR
SLGQSRRLLVAAPSYLAARGTPAVPQDLSAHEGIRMSHVAGSDTLILQGPGGERHAVPFGGRFRIDHGLAAREAFVAGRG
IGPAHRWLVDDLLQTSRLQEILPDYSLPPAPLSMLIVPERAGIARVRLVADFLAEQISGVPGIEKPRPER
>Mature_310_residues
MDKLDVTLERIRTFVRVAERGSLSAVAREQEVGQSTVTRHLRELEEAVGVPLLSRTTRRVTLTDEGSRYYANSVQILRLV
EQAGDEARGTRGAPAGTIRISCTAAFGVLHVSRMIFAFQDRYPNIGVDLSLTDERVDLVREGVDIALRLGPLTDSSMKLR
SLGQSRRLLVAAPSYLAARGTPAVPQDLSAHEGIRMSHVAGSDTLILQGPGGERHAVPFGGRFRIDHGLAAREAFVAGRG
IGPAHRWLVDDLLQTSRLQEILPDYSLPPAPLSMLIVPERAGIARVRLVADFLAEQISGVPGIEKPRPER

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=300, Percent_Identity=32, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=33.2203389830508, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=28.4722222222222, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=27.112676056338, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787128, Length=262, Percent_Identity=28.2442748091603, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=30, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI157672245, Length=228, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787589, Length=189, Percent_Identity=29.1005291005291, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=208, Percent_Identity=25.9615384615385, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=138, Percent_Identity=28.9855072463768, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=148, Percent_Identity=28.3783783783784, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=266, Percent_Identity=25.5639097744361, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788706, Length=168, Percent_Identity=25.5952380952381, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33813; Mature: 33813

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLDVTLERIRTFVRVAERGSLSAVAREQEVGQSTVTRHLRELEEAVGVPLLSRTTRRV
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEE
TLTDEGSRYYANSVQILRLVEQAGDEARGTRGAPAGTIRISCTAAFGVLHVSRMIFAFQD
EEECCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
RYPNIGVDLSLTDERVDLVREGVDIALRLGPLTDSSMKLRSLGQSRRLLVAAPSYLAARG
CCCCCCEEEEECHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCCEEEEECCCHHHCCC
TPAVPQDLSAHEGIRMSHVAGSDTLILQGPGGERHAVPFGGRFRIDHGLAAREAFVAGRG
CCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHCCC
IGPAHRWLVDDLLQTSRLQEILPDYSLPPAPLSMLIVPERAGIARVRLVADFLAEQISGV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCC
PGIEKPRPER
CCCCCCCCCC
>Mature Secondary Structure
MDKLDVTLERIRTFVRVAERGSLSAVAREQEVGQSTVTRHLRELEEAVGVPLLSRTTRRV
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEE
TLTDEGSRYYANSVQILRLVEQAGDEARGTRGAPAGTIRISCTAAFGVLHVSRMIFAFQD
EEECCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
RYPNIGVDLSLTDERVDLVREGVDIALRLGPLTDSSMKLRSLGQSRRLLVAAPSYLAARG
CCCCCCEEEEECHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCCEEEEECCCHHHCCC
TPAVPQDLSAHEGIRMSHVAGSDTLILQGPGGERHAVPFGGRFRIDHGLAAREAFVAGRG
CCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHCCC
IGPAHRWLVDDLLQTSRLQEILPDYSLPPAPLSMLIVPERAGIARVRLVADFLAEQISGV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCC
PGIEKPRPER
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]