Click here to switch to the map view.

The map label for this gene is glpX [H]

Identifier: 182678371

GI number: 182678371

Start: 1592648

End: 1593643

Strand: Direct

Name: glpX [H]

Synonym: Bind_1388

Alternate gene names: 182678371

Gene position: 1592648-1593643 (Clockwise)

Preceding gene: 182678370

Following gene: 182678373

Centisome position: 38.19

GC content: 60.04

Gene sequence:

>996_bases
ATGCCTGATCTCCTTATCAAGAGCCCGGATATTAGCGACCGCATCTTTTCCCTGGAATTCGCACGGGTGACCGAGCGTGC
CGCCGTGGCCGCCGCGCGCCTGCGCGGACGTGGTGACGAGAAAGCTGCCGACAAGGCTGCGGTGGACGCCATGCGGCGCG
AATTGAACCGCTTGCCGATCGACGGCACGATTGTGATCGGCGAAGGCGAGCGCGACGAAGCGCCGATGCTCTATATCGGT
GAGGAAGTTGGCCTGCGCGGCGGCCCGAAGATCGATATTGCCGTCGACCCGCTCGAGGGCACGACCTTGTGCGCCAAGGA
TATGCCGGGCTCGATCGCCGTATTGTCCATGGCTCCCGCTGGCACGCTGCTCAACGCGGCCGATGTTTACATGCAAAAGA
TCGCCATTGGCCCCGGTTATCCAGAGGGTGTCGTCGATCTCGACGCGAGCCCGACCGATAATATTCATGCCCTTGCCAAG
GCCAAGGGTGTCAAGCCGCACGAGATCTCGGTCATGATCATGGATCGCGATCGGCATAAGGATATTATTGCCGAATGCCG
TAAGATCGGTGTCGCGATCCGCCTGATTACCGATGGCGATGTCGTCGGCGTAATCCATACGACCGAACCCGAGGAAACCG
GCATCGATCTTTATATGGGCATCGGCGGAGCGCCGGAAGGCGTGCTGGCGGCAGGGGCCTTGCGTTGCGTCGGCGGTCAA
ATGCAGGGACGCCTGATTTTCGATACGCCGGCCAAGATCGAGCGGGCCCATAAGATGGGCATCGCTGATCCCAACAAAAA
ATATACGCTGAACGAAATGGCTGCCGGCGATACGATCGTCAGCGCGACGGGTGTGACCGATGGCGCCCTTTTGAAGGGGG
TGAAATTCGGCAAGGAGATCATCCGCACCGAGACGATCATCTTCCGCTCGGCGACTGGCACGGTTCGCAAGATCCAGGCG
GAGCATCGCAAGTTGGACAAGTTCGACAGCGAATGA

Upstream 100 bases:

>100_bases
TGTTATACAAACTGTGCGAGAATAAATCCCGACACTATTGGATACGGAGACGGCAAACTCCGTATCTTCGACCGCTCTTC
TTCTGCCAACGGGGACCCCA

Downstream 100 bases:

>100_bases
TCTGTTCTTTGCGGGAGGGATTGATCCCTCCCGTTCATGCCTAGAGCATCAAACCGAAAAGTGGACACCACTTTTCGGAA
AAATTTGATGCTTTTATAAA

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MPDLLIKSPDISDRIFSLEFARVTERAAVAAARLRGRGDEKAADKAAVDAMRRELNRLPIDGTIVIGEGERDEAPMLYIG
EEVGLRGGPKIDIAVDPLEGTTLCAKDMPGSIAVLSMAPAGTLLNAADVYMQKIAIGPGYPEGVVDLDASPTDNIHALAK
AKGVKPHEISVMIMDRDRHKDIIAECRKIGVAIRLITDGDVVGVIHTTEPEETGIDLYMGIGGAPEGVLAAGALRCVGGQ
MQGRLIFDTPAKIERAHKMGIADPNKKYTLNEMAAGDTIVSATGVTDGALLKGVKFGKEIIRTETIIFRSATGTVRKIQA
EHRKLDKFDSE

Sequences:

>Translated_331_residues
MPDLLIKSPDISDRIFSLEFARVTERAAVAAARLRGRGDEKAADKAAVDAMRRELNRLPIDGTIVIGEGERDEAPMLYIG
EEVGLRGGPKIDIAVDPLEGTTLCAKDMPGSIAVLSMAPAGTLLNAADVYMQKIAIGPGYPEGVVDLDASPTDNIHALAK
AKGVKPHEISVMIMDRDRHKDIIAECRKIGVAIRLITDGDVVGVIHTTEPEETGIDLYMGIGGAPEGVLAAGALRCVGGQ
MQGRLIFDTPAKIERAHKMGIADPNKKYTLNEMAAGDTIVSATGVTDGALLKGVKFGKEIIRTETIIFRSATGTVRKIQA
EHRKLDKFDSE
>Mature_330_residues
PDLLIKSPDISDRIFSLEFARVTERAAVAAARLRGRGDEKAADKAAVDAMRRELNRLPIDGTIVIGEGERDEAPMLYIGE
EVGLRGGPKIDIAVDPLEGTTLCAKDMPGSIAVLSMAPAGTLLNAADVYMQKIAIGPGYPEGVVDLDASPTDNIHALAKA
KGVKPHEISVMIMDRDRHKDIIAECRKIGVAIRLITDGDVVGVIHTTEPEETGIDLYMGIGGAPEGVLAAGALRCVGGQM
QGRLIFDTPAKIERAHKMGIADPNKKYTLNEMAAGDTIVSATGVTDGALLKGVKFGKEIIRTETIIFRSATGTVRKIQAE
HRKLDKFDSE

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=332, Percent_Identity=44.578313253012, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1789298, Length=321, Percent_Identity=39.2523364485981, Blast_Score=203, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35344; Mature: 35213

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLLIKSPDISDRIFSLEFARVTERAAVAAARLRGRGDEKAADKAAVDAMRRELNRLPI
CCCCEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
DGTIVIGEGERDEAPMLYIGEEVGLRGGPKIDIAVDPLEGTTLCAKDMPGSIAVLSMAPA
CCEEEECCCCCCCCCEEEECHHCCCCCCCEEEEEECCCCCCEEEECCCCCCEEEEEECCC
GTLLNAADVYMQKIAIGPGYPEGVVDLDASPTDNIHALAKAKGVKPHEISVMIMDRDRHK
CCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCH
DIIAECRKIGVAIRLITDGDVVGVIHTTEPEETGIDLYMGIGGAPEGVLAAGALRCVGGQ
HHHHHHHHCCEEEEEEECCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCC
MQGRLIFDTPAKIERAHKMGIADPNKKYTLNEMAAGDTIVSATGVTDGALLKGVKFGKEI
CCCEEEECCCHHHHHHHHCCCCCCCCCEEEHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
IRTETIIFRSATGTVRKIQAEHRKLDKFDSE
HHHEEEEEECCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PDLLIKSPDISDRIFSLEFARVTERAAVAAARLRGRGDEKAADKAAVDAMRRELNRLPI
CCCEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
DGTIVIGEGERDEAPMLYIGEEVGLRGGPKIDIAVDPLEGTTLCAKDMPGSIAVLSMAPA
CCEEEECCCCCCCCCEEEECHHCCCCCCCEEEEEECCCCCCEEEECCCCCCEEEEEECCC
GTLLNAADVYMQKIAIGPGYPEGVVDLDASPTDNIHALAKAKGVKPHEISVMIMDRDRHK
CCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCH
DIIAECRKIGVAIRLITDGDVVGVIHTTEPEETGIDLYMGIGGAPEGVLAAGALRCVGGQ
HHHHHHHHCCEEEEEEECCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCC
MQGRLIFDTPAKIERAHKMGIADPNKKYTLNEMAAGDTIVSATGVTDGALLKGVKFGKEI
CCCEEEECCCHHHHHHHHCCCCCCCCCEEEHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
IRTETIIFRSATGTVRKIQAEHRKLDKFDSE
HHHEEEEEECCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]