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The map label for this gene is yafC [H]

Identifier: 182678278

GI number: 182678278

Start: 1502079

End: 1503011

Strand: Direct

Name: yafC [H]

Synonym: Bind_1294

Alternate gene names: 182678278

Gene position: 1502079-1503011 (Clockwise)

Preceding gene: 182678273

Following gene: 182678279

Centisome position: 36.02

GC content: 54.56

Gene sequence:

>933_bases
ATGCAGAAACTCGATGACATGATCACTTTCGTCCGTGTCGTCGAACGCGGGAGTTTCGTCGCGGCTGCGCGGCAGCTTGG
AGTGCCTCCCGCCACGGTCAGCCGGAAAGTCCAAGAACTCGAACATCGACTCGGCATCGAATTATTGCGGCGCACGACAC
GCCGGGTTTTCGTTACCGAGGCGGGGCGAGCCTTTTTCGATAATGCATCGCAGGCCTTGACCTTGATCGAGGAAGCGGAG
CTGGTTGCCAAGAGCTATAGCAGCAAGCCTTCGGGCGTGTTGAGGCTGCTTGCTCCTTATACGGTTGGCGTCCTGATCAT
CGATCAGATTTTGCCTGCTTTTCAGCGGCTCTATCCGGAAGTTCTCATCTATCTGACGTTGAACAACGAGCCTCTCGATT
TGATCGAGCATGGTTTCGATGTCGCGATGCGAGTCGGTGCATTGCCTGATTCGACCTATGCGGTCCATCATCTCTTGCGA
ACGGGAAGGCGCATCGTCGCTGCGCCTTCCTATATCGAGAAACACCCGCCGATCGAGACGATTGCCGATCTCGAACATCA
CGTCTTTTTGAGTTTCGCGATTGAGACGCCGCCATCAGGGGTCGTGATGACTTTCAACAGAGGGGAGGAGCAAGCTCAGG
TCACGCTTGCACCTCGCATGGTGATCAACGAGGCCTCGGTCGTTCTCAACCATGTTCTGCGCGGCGAGGGATTCTCGCTC
TTTGGCGATATCCTGACCGACTCTTATCTCGCTAGCGGAGCCCTGAAACATATTCTGCCGGAGTGGCAGAGCGATGATCC
GCTCGAAGTTTCCCTCGTGTTCAGCCGTCACGCCACAAGTGATCCAAAAGTCCGATTGTTTATCGATTTCTTAACACATG
AAGCTATGGCGTCGAAGAAAAGAACGACATTGTTGCTGGGGCTGAGAGAATGA

Upstream 100 bases:

>100_bases
AGGGGCGCTAAATCTTATAACTATTTGTTATATAATAACTATCTGTTAAAGGATAGATTGTTCTGGTTGCTTGATCTCAA
GGAAACGTTCGGTCGGCGCG

Downstream 100 bases:

>100_bases
AATGCTATAATGGCCAATGATCGCCAGGGTTAAGGCGGCTATATTCCTCCTCATGAACGGCGCCGGGACATGGCACCGGA
TGAGGAGCACTCAAATGAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MQKLDDMITFVRVVERGSFVAAARQLGVPPATVSRKVQELEHRLGIELLRRTTRRVFVTEAGRAFFDNASQALTLIEEAE
LVAKSYSSKPSGVLRLLAPYTVGVLIIDQILPAFQRLYPEVLIYLTLNNEPLDLIEHGFDVAMRVGALPDSTYAVHHLLR
TGRRIVAAPSYIEKHPPIETIADLEHHVFLSFAIETPPSGVVMTFNRGEEQAQVTLAPRMVINEASVVLNHVLRGEGFSL
FGDILTDSYLASGALKHILPEWQSDDPLEVSLVFSRHATSDPKVRLFIDFLTHEAMASKKRTTLLLGLRE

Sequences:

>Translated_310_residues
MQKLDDMITFVRVVERGSFVAAARQLGVPPATVSRKVQELEHRLGIELLRRTTRRVFVTEAGRAFFDNASQALTLIEEAE
LVAKSYSSKPSGVLRLLAPYTVGVLIIDQILPAFQRLYPEVLIYLTLNNEPLDLIEHGFDVAMRVGALPDSTYAVHHLLR
TGRRIVAAPSYIEKHPPIETIADLEHHVFLSFAIETPPSGVVMTFNRGEEQAQVTLAPRMVINEASVVLNHVLRGEGFSL
FGDILTDSYLASGALKHILPEWQSDDPLEVSLVFSRHATSDPKVRLFIDFLTHEAMASKKRTTLLLGLRE
>Mature_310_residues
MQKLDDMITFVRVVERGSFVAAARQLGVPPATVSRKVQELEHRLGIELLRRTTRRVFVTEAGRAFFDNASQALTLIEEAE
LVAKSYSSKPSGVLRLLAPYTVGVLIIDQILPAFQRLYPEVLIYLTLNNEPLDLIEHGFDVAMRVGALPDSTYAVHHLLR
TGRRIVAAPSYIEKHPPIETIADLEHHVFLSFAIETPPSGVVMTFNRGEEQAQVTLAPRMVINEASVVLNHVLRGEGFSL
FGDILTDSYLASGALKHILPEWQSDDPLEVSLVFSRHATSDPKVRLFIDFLTHEAMASKKRTTLLLGLRE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=33.4470989761092, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=29.4117647058824, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=29.5918367346939, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=29.6296296296296, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=28.4722222222222, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787128, Length=300, Percent_Identity=24.6666666666667, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787589, Length=299, Percent_Identity=25.0836120401338, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788706, Length=188, Percent_Identity=27.1276595744681, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=238, Percent_Identity=25.2100840336134, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=138, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787879, Length=150, Percent_Identity=31.3333333333333, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34598; Mature: 34598

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLDDMITFVRVVERGSFVAAARQLGVPPATVSRKVQELEHRLGIELLRRTTRRVFVTE
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
AGRAFFDNASQALTLIEEAELVAKSYSSKPSGVLRLLAPYTVGVLIIDQILPAFQRLYPE
CCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIYLTLNNEPLDLIEHGFDVAMRVGALPDSTYAVHHLLRTGRRIVAAPSYIEKHPPIET
EEEEEEECCCCHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCHHHHHCCCHHH
IADLEHHVFLSFAIETPPSGVVMTFNRGEEQAQVTLAPRMVINEASVVLNHVLRGEGFSL
HHCCHHEEEEEEEEECCCCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHH
FGDILTDSYLASGALKHILPEWQSDDPLEVSLVFSRHATSDPKVRLFIDFLTHEAMASKK
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHCC
RTTLLLGLRE
CEEEEEEECC
>Mature Secondary Structure
MQKLDDMITFVRVVERGSFVAAARQLGVPPATVSRKVQELEHRLGIELLRRTTRRVFVTE
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
AGRAFFDNASQALTLIEEAELVAKSYSSKPSGVLRLLAPYTVGVLIIDQILPAFQRLYPE
CCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIYLTLNNEPLDLIEHGFDVAMRVGALPDSTYAVHHLLRTGRRIVAAPSYIEKHPPIET
EEEEEEECCCCHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCHHHHHCCCHHH
IADLEHHVFLSFAIETPPSGVVMTFNRGEEQAQVTLAPRMVINEASVVLNHVLRGEGFSL
HHCCHHEEEEEEEEECCCCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHH
FGDILTDSYLASGALKHILPEWQSDDPLEVSLVFSRHATSDPKVRLFIDFLTHEAMASKK
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHCC
RTTLLLGLRE
CEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]