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The map label for this gene is hypE [H]

Identifier: 182678149

GI number: 182678149

Start: 1345626

End: 1346684

Strand: Direct

Name: hypE [H]

Synonym: Bind_1164

Alternate gene names: 182678149

Gene position: 1345626-1346684 (Clockwise)

Preceding gene: 182678148

Following gene: 182678152

Centisome position: 32.27

GC content: 62.89

Gene sequence:

>1059_bases
ATGAGCGGCGAGGAGCCGATTTCCGGCATTGGTCCTGGCGGCCGGATCACTTTGGCGCATGGAGGTGGCGGCACCGCGAT
GCGCGATTTGATCGAACGCGTCTTTGTCGCCACCTTCCACCCCGAAGGGACGCCACCGCTGGAAGATCAGGCGCGTTTCG
ATCTCGCTGCCTTTGCCGCCCATGGCGATCGGCTGGCTTTTACCACCGACGGTTTCGTGGTCGAGCCGCTGGAATTTCCC
GGCGGTGATATCGGCAAGCTTGCTGTATGCGGTACCGTGAATGATCTTGCCGTGGGCGGCGCGCGGCCCGTGGCCCTTTC
TGCTGGTTTCATCATTGAGGAAGGTCTGGAACTGGAGCGTCTGCGCCGGATCGTGACCTCCATGGCGATGGAGGCCGCGC
GCGCGCAGGTTCCGATTGTCACTGGTGATACCAAAGTCGTCCCGCGCGGCGCTTGTGACGGCCTGTTCATTACCACCACA
GGCATTGGCGTCATAAGGCCGGATTATCAGATCAGCATTGCCGGCGCGCGGCCGGGTGATGTGATCCTGATCAATGGGTC
TCTGGGCGACCATGGCGCGGCGATTCTCTGCGCGCGCGGTGATCTCGCGCTTGACGTCACGATTAAAAGTGATTGCGCGC
CTTTGCATGATCTCGCAGCGGCTTTGCTCCAGGCGGTGCCGCAGGTGCGTGCCATGCGGGATGCCACGCGTGGCGGTTTG
GCTGGGGTGCTGACGGAATTGGCCGAGGCGAGCCGTGTCGCTATCGGGGTGGATGAAGCGGCTCTGCCGGTCAGATCCGA
AGTCGCCGGCGTCTGCGAGATTTTGGGCCTCGATCCGCTTTATCTCGCCAATGAAGGGAAATTGGTGGCCGTGGTCGCGC
CGGAACATGCGGAAGCGGCATTGGAGGCGATGCGCGCGCATCCCTTGGGTGTGGATGCGGCGATCATTGGAAAGGTCGCG
GCAGAAGGTCGGCCCGGCACCGTGACATTGATCAATCGTTTCGGTGGACGCCGCGCGGTCACGATGCCGTCCGGCGAACA
ACTCCCGCGTATCTGCTGA

Upstream 100 bases:

>100_bases
GCACGACCTGCCGGCCTGACGCGCCTCTTGGCGCCCTCATGGTGTCATCCGAGGGAGCCTGCGCGGCTTACTACCAATAT
CAAGGAATGAAGGGGGCCGC

Downstream 100 bases:

>100_bases
ACGACGAATTTGGATCTCATCGTTCGGATGGGGCGGCCCGCAAATGGAAGCGTTCGCGGGCCGCTTTTATTTTATTTGGT
CGCGTGATGCTCAGAGACAC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSGEEPISGIGPGGRITLAHGGGGTAMRDLIERVFVATFHPEGTPPLEDQARFDLAAFAAHGDRLAFTTDGFVVEPLEFP
GGDIGKLAVCGTVNDLAVGGARPVALSAGFIIEEGLELERLRRIVTSMAMEAARAQVPIVTGDTKVVPRGACDGLFITTT
GIGVIRPDYQISIAGARPGDVILINGSLGDHGAAILCARGDLALDVTIKSDCAPLHDLAAALLQAVPQVRAMRDATRGGL
AGVLTELAEASRVAIGVDEAALPVRSEVAGVCEILGLDPLYLANEGKLVAVVAPEHAEAALEAMRAHPLGVDAAIIGKVA
AEGRPGTVTLINRFGGRRAVTMPSGEQLPRIC

Sequences:

>Translated_352_residues
MSGEEPISGIGPGGRITLAHGGGGTAMRDLIERVFVATFHPEGTPPLEDQARFDLAAFAAHGDRLAFTTDGFVVEPLEFP
GGDIGKLAVCGTVNDLAVGGARPVALSAGFIIEEGLELERLRRIVTSMAMEAARAQVPIVTGDTKVVPRGACDGLFITTT
GIGVIRPDYQISIAGARPGDVILINGSLGDHGAAILCARGDLALDVTIKSDCAPLHDLAAALLQAVPQVRAMRDATRGGL
AGVLTELAEASRVAIGVDEAALPVRSEVAGVCEILGLDPLYLANEGKLVAVVAPEHAEAALEAMRAHPLGVDAAIIGKVA
AEGRPGTVTLINRFGGRRAVTMPSGEQLPRIC
>Mature_351_residues
SGEEPISGIGPGGRITLAHGGGGTAMRDLIERVFVATFHPEGTPPLEDQARFDLAAFAAHGDRLAFTTDGFVVEPLEFPG
GDIGKLAVCGTVNDLAVGGARPVALSAGFIIEEGLELERLRRIVTSMAMEAARAQVPIVTGDTKVVPRGACDGLFITTTG
IGVIRPDYQISIAGARPGDVILINGSLGDHGAAILCARGDLALDVTIKSDCAPLHDLAAALLQAVPQVRAMRDATRGGLA
GVLTELAEASRVAIGVDEAALPVRSEVAGVCEILGLDPLYLANEGKLVAVVAPEHAEAALEAMRAHPLGVDAAIIGKVAA
EGRPGTVTLINRFGGRRAVTMPSGEQLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=339, Percent_Identity=53.0973451327434, Blast_Score=318, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36200; Mature: 36069

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEEPISGIGPGGRITLAHGGGGTAMRDLIERVFVATFHPEGTPPLEDQARFDLAAFAA
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHEEEEC
HGDRLAFTTDGFVVEPLEFPGGDIGKLAVCGTVNDLAVGGARPVALSAGFIIEEGLELER
CCCEEEEEECCEEEEEEECCCCCCCCEEEECCCHHHHCCCCCCEEEECCCHHHCCCCHHH
LRRIVTSMAMEAARAQVPIVTGDTKVVPRGACDGLFITTTGIGVIRPDYQISIAGARPGD
HHHHHHHHHHHHHHCCCEEEECCCEECCCCCCCCEEEEECCCEEECCCEEEEEECCCCCC
VILINGSLGDHGAAILCARGDLALDVTIKSDCAPLHDLAAALLQAVPQVRAMRDATRGGL
EEEEECCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
AGVLTELAEASRVAIGVDEAALPVRSEVAGVCEILGLDPLYLANEGKLVAVVAPEHAEAA
HHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHH
LEAMRAHPLGVDAAIIGKVAAEGRPGTVTLINRFGGRRAVTMPSGEQLPRIC
HHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
SGEEPISGIGPGGRITLAHGGGGTAMRDLIERVFVATFHPEGTPPLEDQARFDLAAFAA
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHEEEEC
HGDRLAFTTDGFVVEPLEFPGGDIGKLAVCGTVNDLAVGGARPVALSAGFIIEEGLELER
CCCEEEEEECCEEEEEEECCCCCCCCEEEECCCHHHHCCCCCCEEEECCCHHHCCCCHHH
LRRIVTSMAMEAARAQVPIVTGDTKVVPRGACDGLFITTTGIGVIRPDYQISIAGARPGD
HHHHHHHHHHHHHHCCCEEEECCCEECCCCCCCCEEEEECCCEEECCCEEEEEECCCCCC
VILINGSLGDHGAAILCARGDLALDVTIKSDCAPLHDLAAALLQAVPQVRAMRDATRGGL
EEEEECCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
AGVLTELAEASRVAIGVDEAALPVRSEVAGVCEILGLDPLYLANEGKLVAVVAPEHAEAA
HHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHH
LEAMRAHPLGVDAAIIGKVAAEGRPGTVTLINRFGGRRAVTMPSGEQLPRIC
HHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]