Click here to switch to the map view.

The map label for this gene is ubiB [C]

Identifier: 182678062

GI number: 182678062

Start: 1233869

End: 1235230

Strand: Direct

Name: ubiB [C]

Synonym: Bind_1076

Alternate gene names: 182678062

Gene position: 1233869-1235230 (Clockwise)

Preceding gene: 182678061

Following gene: 182678063

Centisome position: 29.59

GC content: 58.96

Gene sequence:

>1362_bases
ATGCAAGATAATGAAGCGAACCGCTTTTCCGCCCGCGCCGCGCGCTATGCCCGTGTCGGTGTCAATGTCGGCGGCGTCGC
GGCGCGGATTGCCGGCGCGCGACTGACTGGACTGCGGGGCAGCGAGAGCGGCAATGCGCGGGCGCTTGCCAAAGCGCTGG
GTGGTCTCAAGGGACCCATGATGAAAGTCGCCCAGATGATGGCGACCATACCGGATATTCTGCCACCCGAATATGCCGAG
GAATTGCTGAAACTGCAGAACGAAGCGCCGCCAATGGGCGCGGCTTTCGTCAAGCGTCGCATGCAGGGCGAATTGGGGGA
GGGCTGGCAGAAACGGTTCGGCGCTTTTGATCTACATCCAGCGGCGGCCGCCTCGCTGGGGCAGGTCCACCGTGCGCGCA
TGCAGGATGGGACGGTACTTGCCTGCAAGCTGCAATATCCGGATATGGCCTCAGCCGTCGAGGCCGATCTCAAGCAACTC
GATCTGCTCTTTTCCTTGCACCGGCGCGTCAATCCCGCGATCGACACGCGCGATATGGTGAAGGAAATCTCAGAGCGGGT
CCGCGAAGAGCTCGATTATAAGCGCGAGGCGCGCCATGCCGCGCTTTACAAGCATATCTTGCAAGGCCGCGAGGAGGTGC
GCGTCCCGCGCGTTTATCCAGAACTCTCGACGAAACGGCTCTTATCAATGGATTGGCTCGAAGGCGAAAAGCTTCTCGCT
TTCACCAAACATCCGCAAGAGATCCGCAACCGGATCGGGGCCGCCATGTTCAATGCCTGGTGGATTCCCTTCATCCATTA
TGCCGTGATTCATGGCGATCCGCATTTCGGCAATTACGCAGTCTTCACGGAAGCAGGCGAACCGGCGGGTATCAATTTGC
TTGATTACGGTTGTATTCGACTCTTTCAGGCTCATTTCGTCGAAGGTGTGCGCGAGCTTTATACGGGCTTTCTGACCCAT
GATTTCGACCGCACTGTTCATGCCTATGACATTTGGGGCTTCAAGGGCCTAACGCGCGAACATGTCGAAATCCTGAATAT
CTGGGCGCGTTTCATGTATGGCCCCTTGCTCGATGATCGCGTGCGGACGGTGGCTGATGGCGTCTCGCCGAGCCAATATG
GCCGCAAGGAGGCCTTCACGGTGCATCAGGCTCTCCGCAAGGCGGGTGGGGTGCGGGTACCGCAGGAATTCGTCTTCATG
GATCGCGCGGCGGTCGGGCTTGGGGGCGCCTATCTGCATCTCGGTGCCAAGCTCAATTTCTATCGCTTGTTCAATGAAGC
GCTTGCTGATTTCGACGCAGAGGTTTTGCGCATACGGCAAGCAGAGGCGCTCGCCAACGTGGGTCTGCCGAGTCCTACCT
AG

Upstream 100 bases:

>100_bases
TTGGAATAAACCGCCCCACAGGTATCAATCATCGCGTCCCGAGACTATATGAGCCTCGAACCTTTGTCCTTGCTCCCTTT
CATCCCGAGTTCGATCATCC

Downstream 100 bases:

>100_bases
CCGAGTCCTATCTAGCCAAGGTCCAGCCTGAAATGAGCTGTGTTAAAAACGCAACGCTCGATTGGGAAAGTTAAAGGGTC
ATTGCGAATGACAGTCGCGT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MQDNEANRFSARAARYARVGVNVGGVAARIAGARLTGLRGSESGNARALAKALGGLKGPMMKVAQMMATIPDILPPEYAE
ELLKLQNEAPPMGAAFVKRRMQGELGEGWQKRFGAFDLHPAAAASLGQVHRARMQDGTVLACKLQYPDMASAVEADLKQL
DLLFSLHRRVNPAIDTRDMVKEISERVREELDYKREARHAALYKHILQGREEVRVPRVYPELSTKRLLSMDWLEGEKLLA
FTKHPQEIRNRIGAAMFNAWWIPFIHYAVIHGDPHFGNYAVFTEAGEPAGINLLDYGCIRLFQAHFVEGVRELYTGFLTH
DFDRTVHAYDIWGFKGLTREHVEILNIWARFMYGPLLDDRVRTVADGVSPSQYGRKEAFTVHQALRKAGGVRVPQEFVFM
DRAAVGLGGAYLHLGAKLNFYRLFNEALADFDAEVLRIRQAEALANVGLPSPT

Sequences:

>Translated_453_residues
MQDNEANRFSARAARYARVGVNVGGVAARIAGARLTGLRGSESGNARALAKALGGLKGPMMKVAQMMATIPDILPPEYAE
ELLKLQNEAPPMGAAFVKRRMQGELGEGWQKRFGAFDLHPAAAASLGQVHRARMQDGTVLACKLQYPDMASAVEADLKQL
DLLFSLHRRVNPAIDTRDMVKEISERVREELDYKREARHAALYKHILQGREEVRVPRVYPELSTKRLLSMDWLEGEKLLA
FTKHPQEIRNRIGAAMFNAWWIPFIHYAVIHGDPHFGNYAVFTEAGEPAGINLLDYGCIRLFQAHFVEGVRELYTGFLTH
DFDRTVHAYDIWGFKGLTREHVEILNIWARFMYGPLLDDRVRTVADGVSPSQYGRKEAFTVHQALRKAGGVRVPQEFVFM
DRAAVGLGGAYLHLGAKLNFYRLFNEALADFDAEVLRIRQAEALANVGLPSPT
>Mature_453_residues
MQDNEANRFSARAARYARVGVNVGGVAARIAGARLTGLRGSESGNARALAKALGGLKGPMMKVAQMMATIPDILPPEYAE
ELLKLQNEAPPMGAAFVKRRMQGELGEGWQKRFGAFDLHPAAAASLGQVHRARMQDGTVLACKLQYPDMASAVEADLKQL
DLLFSLHRRVNPAIDTRDMVKEISERVREELDYKREARHAALYKHILQGREEVRVPRVYPELSTKRLLSMDWLEGEKLLA
FTKHPQEIRNRIGAAMFNAWWIPFIHYAVIHGDPHFGNYAVFTEAGEPAGINLLDYGCIRLFQAHFVEGVRELYTGFLTH
DFDRTVHAYDIWGFKGLTREHVEILNIWARFMYGPLLDDRVRTVADGVSPSQYGRKEAFTVHQALRKAGGVRVPQEFVFM
DRAAVGLGGAYLHLGAKLNFYRLFNEALADFDAEVLRIRQAEALANVGLPSPT

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI27363457, Length=311, Percent_Identity=26.6881028938907, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI40254938, Length=284, Percent_Identity=26.7605633802817, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI34147522, Length=305, Percent_Identity=26.2295081967213, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI217416386, Length=255, Percent_Identity=27.4509803921569, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI41393593, Length=270, Percent_Identity=29.2592592592593, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI217035081, Length=222, Percent_Identity=27.9279279279279, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI2367309, Length=280, Percent_Identity=24.2857142857143, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI32565180, Length=341, Percent_Identity=26.9794721407625, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17559152, Length=265, Percent_Identity=27.1698113207547, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=273, Percent_Identity=28.9377289377289, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6323282, Length=317, Percent_Identity=25.5520504731861, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI18859849, Length=287, Percent_Identity=27.1777003484321, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI22024280, Length=347, Percent_Identity=25.0720461095101, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24662575, Length=246, Percent_Identity=28.8617886178862, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 50724; Mature: 50724

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDNEANRFSARAARYARVGVNVGGVAARIAGARLTGLRGSESGNARALAKALGGLKGPM
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHH
MKVAQMMATIPDILPPEYAEELLKLQNEAPPMGAAFVKRRMQGELGEGWQKRFGAFDLHP
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCH
AAAASLGQVHRARMQDGTVLACKLQYPDMASAVEADLKQLDLLFSLHRRVNPAIDTRDMV
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KEISERVREELDYKREARHAALYKHILQGREEVRVPRVYPELSTKRLLSMDWLEGEKLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEE
FTKHPQEIRNRIGAAMFNAWWIPFIHYAVIHGDPHFGNYAVFTEAGEPAGINLLDYGCIR
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCCCHHHHHHHH
LFQAHFVEGVRELYTGFLTHDFDRTVHAYDIWGFKGLTREHVEILNIWARFMYGPLLDDR
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHH
VRTVADGVSPSQYGRKEAFTVHQALRKAGGVRVPQEFVFMDRAAVGLGGAYLHLGAKLNF
HHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHEEECCCHHH
YRLFNEALADFDAEVLRIRQAEALANVGLPSPT
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQDNEANRFSARAARYARVGVNVGGVAARIAGARLTGLRGSESGNARALAKALGGLKGPM
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHH
MKVAQMMATIPDILPPEYAEELLKLQNEAPPMGAAFVKRRMQGELGEGWQKRFGAFDLHP
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCH
AAAASLGQVHRARMQDGTVLACKLQYPDMASAVEADLKQLDLLFSLHRRVNPAIDTRDMV
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KEISERVREELDYKREARHAALYKHILQGREEVRVPRVYPELSTKRLLSMDWLEGEKLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEE
FTKHPQEIRNRIGAAMFNAWWIPFIHYAVIHGDPHFGNYAVFTEAGEPAGINLLDYGCIR
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCCCHHHHHHHH
LFQAHFVEGVRELYTGFLTHDFDRTVHAYDIWGFKGLTREHVEILNIWARFMYGPLLDDR
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHH
VRTVADGVSPSQYGRKEAFTVHQALRKAGGVRVPQEFVFMDRAAVGLGGAYLHLGAKLNF
HHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHEEECCCHHH
YRLFNEALADFDAEVLRIRQAEALANVGLPSPT
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]