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The map label for this gene is lysK [H]

Identifier: 182678051

GI number: 182678051

Start: 1222765

End: 1224468

Strand: Direct

Name: lysK [H]

Synonym: Bind_1065

Alternate gene names: 182678051

Gene position: 1222765-1224468 (Clockwise)

Preceding gene: 182678050

Following gene: 182678052

Centisome position: 29.32

GC content: 58.92

Gene sequence:

>1704_bases
ATGTCTGCCGCCGAGCCGGCCACAGCGCCGCTTTCCTTGTCTGAAGCCGTTGCCAAGGCCAATGCCTGGCCGTTCGAGGA
AGCGCGCAAGATCGTCAAACGGGTCGAGGCAACCGGCCAGAAGGAAGTTCTGTTCGAGACCGGCTATGGTCCCTCCGGTC
TGCCGCATATCGGCACGTTTGGCGAGGTCGCCCGCACGACCATGGTGCGCCATGCGTTTCGCATCTTGACCGAGGATAAG
ATCAAGACGCGGCTTCTGGCGTTTTCCGACGATATGGACGGCCTGCGCAAAGTGCCGGACAATATTCCGAACAAGGAGCT
CGTCGCTGCTTATCTCGGTAAGCCTTTGACCCAGGTGCCGGATCCTTTCGGCACGCATTCGAGCTTTGGCGCGCATAATA
ATGCGCGGCTGCGCGCCTTTCTCGATTCGTTCGGCTTCGAGTATGAATTTGCGTCCTCGACCGAATATTATACGTCTGGT
CGCTTCGATAGCGCGCTTTTGCACATGCTCCGCCATCTCGATGAGGTCATGGCGATCATGCTGCCGACTTTCCGCGAGGA
ACGGGCCGCCACTTATTCCCCTTTCCTGCCGATCCATCCGCGCACGGGCATCGTCATGCAGGTGCCGCTCGAAAAGACCG
ATCCGCAAGCAGGAACAATCGTCTGGCGTGATCCCGACACGGGTGAGGTGTTCGAGACGCCAGTGACGGGGGGCCATTGC
AAGCTGCAATGGAAGCCCGATTGGGCAATGCGCTGGTACGCGCTTGGTGTCGATTATGAAATGGCTGGCAAGGATCTCAT
CGATTCCGTCAAGCTTTCGGGCCGCATCGTCCAGGCGCTTGGGGGCAAGCCGCCGGAGGGTTTCAACTACGAACTCTTCC
TCGATGAAAAAGGTCAGAAGATCTCAAAGTCGAAAGGCAATGGCCTGACGATCGAGGAATGGCTGACCTATGCGAGCCCG
GAAAGCCTCTCGCTTTTCATGTATCAGAAGCCGACGGCCGCCAAGCGTCTCTATTTCGATGTGATTCCGCGCACGGTCGA
TGATTATTTGAGTTTTCTCGACGCCTATCCCCGTCAGGCGATCAAGGAACAGCTCGGCAATCCGGTCTGGCACATCCATA
CGGGTCATCCGCCGGAGCCCGAAACCCTGACCCATGGCGGGCAGGCGACGGCCATTTCCTTCGGCATGCTCCTGAATCTC
GCCGCGGTCGCCAATAGCGAGGACTCGCAGGTTCTCTGGGGTTTTCTGCGCCGTTACGCGCCCAATGTCTCGCCGCAGAA
TCATCCGCGTCTCGATCAGCTTGTTGGTTATGCGGTGCGCTATTTCCGCGATTTCGTGCGGCCGGCCAAGACCTATCGTG
AGCCCGATGAGGTCGAAGTGGGAGCGCTCCATAATCTTCTCGATATGCTGGCGGCTTTGCCGGAAGGCGCCAGTGCCGAG
GAGATCCAGACCGCGCTCTATGATGTCGCGCGCGCCATTCCGCGTTATCAGGATTTCAAGGCCAAGGGAGCGACAGAAGA
GCGGCCCGGCGTCTCGAATGATTGGTTCAGTATGCTCTATGCTGTGTTGCTCGGAGAGGCCCGGGGTCCCCGTTTCGGTT
CCTTCGTGGCACTTTATGGAATCGCCGAGACGCGCGCTCTGATCGAGAAGGCGCTGAAGGGCGACCTCACGCGCGAGCAT
GCCCTTTTCTTGCAGGGCCAATGA

Upstream 100 bases:

>100_bases
GGAATTCCCTCGCGTTAAAAATTATTCTAGAGGATATTTTCTTGGTCTTGCGCCGGGCTGGCCAGCCGCGCAAACTTTCT
CCCTGTCGAGGATTTGTCTC

Downstream 100 bases:

>100_bases
GGAACGGGCTGCCGTTCGTTCCTCTCTATTCCCTTGGAGAATGATCCATGGCTTTTTCAGAGCCGCTCGAAACCGGTGCC
GATTGGGCCGATGCCAAGGC

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MSAAEPATAPLSLSEAVAKANAWPFEEARKIVKRVEATGQKEVLFETGYGPSGLPHIGTFGEVARTTMVRHAFRILTEDK
IKTRLLAFSDDMDGLRKVPDNIPNKELVAAYLGKPLTQVPDPFGTHSSFGAHNNARLRAFLDSFGFEYEFASSTEYYTSG
RFDSALLHMLRHLDEVMAIMLPTFREERAATYSPFLPIHPRTGIVMQVPLEKTDPQAGTIVWRDPDTGEVFETPVTGGHC
KLQWKPDWAMRWYALGVDYEMAGKDLIDSVKLSGRIVQALGGKPPEGFNYELFLDEKGQKISKSKGNGLTIEEWLTYASP
ESLSLFMYQKPTAAKRLYFDVIPRTVDDYLSFLDAYPRQAIKEQLGNPVWHIHTGHPPEPETLTHGGQATAISFGMLLNL
AAVANSEDSQVLWGFLRRYAPNVSPQNHPRLDQLVGYAVRYFRDFVRPAKTYREPDEVEVGALHNLLDMLAALPEGASAE
EIQTALYDVARAIPRYQDFKAKGATEERPGVSNDWFSMLYAVLLGEARGPRFGSFVALYGIAETRALIEKALKGDLTREH
ALFLQGQ

Sequences:

>Translated_567_residues
MSAAEPATAPLSLSEAVAKANAWPFEEARKIVKRVEATGQKEVLFETGYGPSGLPHIGTFGEVARTTMVRHAFRILTEDK
IKTRLLAFSDDMDGLRKVPDNIPNKELVAAYLGKPLTQVPDPFGTHSSFGAHNNARLRAFLDSFGFEYEFASSTEYYTSG
RFDSALLHMLRHLDEVMAIMLPTFREERAATYSPFLPIHPRTGIVMQVPLEKTDPQAGTIVWRDPDTGEVFETPVTGGHC
KLQWKPDWAMRWYALGVDYEMAGKDLIDSVKLSGRIVQALGGKPPEGFNYELFLDEKGQKISKSKGNGLTIEEWLTYASP
ESLSLFMYQKPTAAKRLYFDVIPRTVDDYLSFLDAYPRQAIKEQLGNPVWHIHTGHPPEPETLTHGGQATAISFGMLLNL
AAVANSEDSQVLWGFLRRYAPNVSPQNHPRLDQLVGYAVRYFRDFVRPAKTYREPDEVEVGALHNLLDMLAALPEGASAE
EIQTALYDVARAIPRYQDFKAKGATEERPGVSNDWFSMLYAVLLGEARGPRFGSFVALYGIAETRALIEKALKGDLTREH
ALFLQGQ
>Mature_566_residues
SAAEPATAPLSLSEAVAKANAWPFEEARKIVKRVEATGQKEVLFETGYGPSGLPHIGTFGEVARTTMVRHAFRILTEDKI
KTRLLAFSDDMDGLRKVPDNIPNKELVAAYLGKPLTQVPDPFGTHSSFGAHNNARLRAFLDSFGFEYEFASSTEYYTSGR
FDSALLHMLRHLDEVMAIMLPTFREERAATYSPFLPIHPRTGIVMQVPLEKTDPQAGTIVWRDPDTGEVFETPVTGGHCK
LQWKPDWAMRWYALGVDYEMAGKDLIDSVKLSGRIVQALGGKPPEGFNYELFLDEKGQKISKSKGNGLTIEEWLTYASPE
SLSLFMYQKPTAAKRLYFDVIPRTVDDYLSFLDAYPRQAIKEQLGNPVWHIHTGHPPEPETLTHGGQATAISFGMLLNLA
AVANSEDSQVLWGFLRRYAPNVSPQNHPRLDQLVGYAVRYFRDFVRPAKTYREPDEVEVGALHNLLDMLAALPEGASAEE
IQTALYDVARAIPRYQDFKAKGATEERPGVSNDWFSMLYAVLLGEARGPRFGSFVALYGIAETRALIEKALKGDLTREHA
LFLQGQ

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 63308; Mature: 63176

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAEPATAPLSLSEAVAKANAWPFEEARKIVKRVEATGQKEVLFETGYGPSGLPHIGTF
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCH
GEVARTTMVRHAFRILTEDKIKTRLLAFSDDMDGLRKVPDNIPNKELVAAYLGKPLTQVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHCCCHHHCC
DPFGTHSSFGAHNNARLRAFLDSFGFEYEFASSTEYYTSGRFDSALLHMLRHLDEVMAIM
CCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPTFREERAATYSPFLPIHPRTGIVMQVPLEKTDPQAGTIVWRDPDTGEVFETPVTGGHC
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEECCCCCCEE
KLQWKPDWAMRWYALGVDYEMAGKDLIDSVKLSGRIVQALGGKPPEGFNYELFLDEKGQK
EEEECCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCH
ISKSKGNGLTIEEWLTYASPESLSLFMYQKPTAAKRLYFDVIPRTVDDYLSFLDAYPRQA
HHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKEQLGNPVWHIHTGHPPEPETLTHGGQATAISFGMLLNLAAVANSEDSQVLWGFLRRYA
HHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PNVSPQNHPRLDQLVGYAVRYFRDFVRPAKTYREPDEVEVGALHNLLDMLAALPEGASAE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHH
EIQTALYDVARAIPRYQDFKAKGATEERPGVSNDWFSMLYAVLLGEARGPRFGSFVALYG
HHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IAETRALIEKALKGDLTREHALFLQGQ
HHHHHHHHHHHHHCCCCCCCEEEEECC
>Mature Secondary Structure 
SAAEPATAPLSLSEAVAKANAWPFEEARKIVKRVEATGQKEVLFETGYGPSGLPHIGTF
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCH
GEVARTTMVRHAFRILTEDKIKTRLLAFSDDMDGLRKVPDNIPNKELVAAYLGKPLTQVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHCCCHHHCC
DPFGTHSSFGAHNNARLRAFLDSFGFEYEFASSTEYYTSGRFDSALLHMLRHLDEVMAIM
CCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPTFREERAATYSPFLPIHPRTGIVMQVPLEKTDPQAGTIVWRDPDTGEVFETPVTGGHC
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEECCCCCCEE
KLQWKPDWAMRWYALGVDYEMAGKDLIDSVKLSGRIVQALGGKPPEGFNYELFLDEKGQK
EEEECCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCH
ISKSKGNGLTIEEWLTYASPESLSLFMYQKPTAAKRLYFDVIPRTVDDYLSFLDAYPRQA
HHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKEQLGNPVWHIHTGHPPEPETLTHGGQATAISFGMLLNLAAVANSEDSQVLWGFLRRYA
HHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PNVSPQNHPRLDQLVGYAVRYFRDFVRPAKTYREPDEVEVGALHNLLDMLAALPEGASAE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHH
EIQTALYDVARAIPRYQDFKAKGATEERPGVSNDWFSMLYAVLLGEARGPRFGSFVALYG
HHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IAETRALIEKALKGDLTREHALFLQGQ
HHHHHHHHHHHHHCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]