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The map label for this gene is tlyC [H]

Identifier: 182678044

GI number: 182678044

Start: 1214252

End: 1215286

Strand: Direct

Name: tlyC [H]

Synonym: Bind_1058

Alternate gene names: 182678044

Gene position: 1214252-1215286 (Clockwise)

Preceding gene: 182678043

Following gene: 182678045

Centisome position: 29.12

GC content: 58.94

Gene sequence:

>1035_bases
ATGAGTGAACGCGACACCTATGCGGCAGGTGAAAATGCCGTGCCTGATCGGGGCGGGCAGGGCCAACGGCCCAATCTGAT
TGATCGCTTGCGCCTTTTGTTCGGTCTCGGTGGCCCGACGATCCGCGATGAATTGCAGGAGGCCTTGAGCGATACGGCCA
CCGACGCAGAAATTTCACCGCAACAGCGGACCATGCTGAAGAATGTCCTCGGTCTGCATGAGGTGCGGGTCGAAGATGTC
ATGGTGCCGCGCACTGATATTATCGCCGTCTCGCTCGACTCGACCCTTGCCGAGGTCCTGGATCTGTTCCGTTCCGCTGG
CCATTCTCGTCTGCCCGTGCATGGCGACACGCTCGACGATCCACGCGGTATGGTCCACATCCGCGATTTCGTCGATTATC
TTGCCGGTCTCGCCTTGCCTGAAACCGAGACGGTCCCGTCTCATGCCGACAAAACGCCGCCGGCGGTGGTGAAGACGCTG
GCCGGCCCGTATAAGCTCGATATTGGCGCGACGACATTGGCCGAAGCCAAGATCCTGCGGCCCGTTTTGTTCGTGCCCCC
CTCCATGCCGGTCCTTGATCTGCTCGTGAAAATGCAGGCGACCCGCACGCATATGGCGTTGGTCATCGACGAATATGGCG
GGACAGACGGTTTGGCCTCGATCGAGGATATTGTCGAAATGATTGTCGGTGATATCGAAGACGAGCATGATTTGGAGGAA
AGTCCTAAAATCGAAGCGACGGAAGACGGCGCTTTCATCGTCGATGCGCGCGCCGATCTCGAGGAAGTCGGTGCCGTGAC
GGGGATCGACTTTGAGGCGATGGATGTCACAGAGTCTTTCGATACGCTCGGGGGGCTGATCACCGCCATGATGGGGCATG
TGCCCGTCCGGGGCGAAATGATCGAAGAAGGGACGCTCAGTTTCGAAATTCTCGACGCCGACCGGCAAAAGATCGAACGC
ATCAAGATTTATGGCGCGCCGGGCGGGCGCGTTGGCGAGGAAACAGGCTACGTCGCAGAGAAAGGCAAAGCGTGA

Upstream 100 bases:

>100_bases
CACAGGTGCCGAACGAGGCATTGGAAACGAGCGGGAAGCGCCAAGACCATTCGCTTGGTGAGATTCTCCCAGGGGGAATG
TCGAGGCGGCTGGCAGGATC

Downstream 100 bases:

>100_bases
GCCGGCGGCCCTCATGATGCGGTTTTTATCCCGCATCCCGGGCCTGACAGGCTGGCGGCGTCATGGGCTTGCCTTTGGCG
CTGGCGCGAGCGGTGCGCTG

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSERDTYAAGENAVPDRGGQGQRPNLIDRLRLLFGLGGPTIRDELQEALSDTATDAEISPQQRTMLKNVLGLHEVRVEDV
MVPRTDIIAVSLDSTLAEVLDLFRSAGHSRLPVHGDTLDDPRGMVHIRDFVDYLAGLALPETETVPSHADKTPPAVVKTL
AGPYKLDIGATTLAEAKILRPVLFVPPSMPVLDLLVKMQATRTHMALVIDEYGGTDGLASIEDIVEMIVGDIEDEHDLEE
SPKIEATEDGAFIVDARADLEEVGAVTGIDFEAMDVTESFDTLGGLITAMMGHVPVRGEMIEEGTLSFEILDADRQKIER
IKIYGAPGGRVGEETGYVAEKGKA

Sequences:

>Translated_344_residues
MSERDTYAAGENAVPDRGGQGQRPNLIDRLRLLFGLGGPTIRDELQEALSDTATDAEISPQQRTMLKNVLGLHEVRVEDV
MVPRTDIIAVSLDSTLAEVLDLFRSAGHSRLPVHGDTLDDPRGMVHIRDFVDYLAGLALPETETVPSHADKTPPAVVKTL
AGPYKLDIGATTLAEAKILRPVLFVPPSMPVLDLLVKMQATRTHMALVIDEYGGTDGLASIEDIVEMIVGDIEDEHDLEE
SPKIEATEDGAFIVDARADLEEVGAVTGIDFEAMDVTESFDTLGGLITAMMGHVPVRGEMIEEGTLSFEILDADRQKIER
IKIYGAPGGRVGEETGYVAEKGKA
>Mature_343_residues
SERDTYAAGENAVPDRGGQGQRPNLIDRLRLLFGLGGPTIRDELQEALSDTATDAEISPQQRTMLKNVLGLHEVRVEDVM
VPRTDIIAVSLDSTLAEVLDLFRSAGHSRLPVHGDTLDDPRGMVHIRDFVDYLAGLALPETETVPSHADKTPPAVVKTLA
GPYKLDIGATTLAEAKILRPVLFVPPSMPVLDLLVKMQATRTHMALVIDEYGGTDGLASIEDIVEMIVGDIEDEHDLEES
PKIEATEDGAFIVDARADLEEVGAVTGIDFEAMDVTESFDTLGGLITAMMGHVPVRGEMIEEGTLSFEILDADRQKIERI
KIYGAPGGRVGEETGYVAEKGKA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=250, Percent_Identity=25.2, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1786879, Length=287, Percent_Identity=31.7073170731707, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI145693175, Length=289, Percent_Identity=25.2595155709343, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082033, Length=283, Percent_Identity=24.0282685512367, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788119, Length=294, Percent_Identity=23.1292517006803, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 37192; Mature: 37060

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERDTYAAGENAVPDRGGQGQRPNLIDRLRLLFGLGGPTIRDELQEALSDTATDAEISP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCH
QQRTMLKNVLGLHEVRVEDVMVPRTDIIAVSLDSTLAEVLDLFRSAGHSRLPVHGDTLDD
HHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PRGMVHIRDFVDYLAGLALPETETVPSHADKTPPAVVKTLAGPYKLDIGATTLAEAKILR
CCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHC
PVLFVPPSMPVLDLLVKMQATRTHMALVIDEYGGTDGLASIEDIVEMIVGDIEDEHDLEE
CEEECCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
SPKIEATEDGAFIVDARADLEEVGAVTGIDFEAMDVTESFDTLGGLITAMMGHVPVRGEM
CCCCEEECCCCEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IEEGTLSFEILDADRQKIERIKIYGAPGGRVGEETGYVAEKGKA
CCCCCEEEEEECCHHHCEEEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SERDTYAAGENAVPDRGGQGQRPNLIDRLRLLFGLGGPTIRDELQEALSDTATDAEISP
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCH
QQRTMLKNVLGLHEVRVEDVMVPRTDIIAVSLDSTLAEVLDLFRSAGHSRLPVHGDTLDD
HHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PRGMVHIRDFVDYLAGLALPETETVPSHADKTPPAVVKTLAGPYKLDIGATTLAEAKILR
CCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHC
PVLFVPPSMPVLDLLVKMQATRTHMALVIDEYGGTDGLASIEDIVEMIVGDIEDEHDLEE
CEEECCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
SPKIEATEDGAFIVDARADLEEVGAVTGIDFEAMDVTESFDTLGGLITAMMGHVPVRGEM
CCCCEEECCCCEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IEEGTLSFEILDADRQKIERIKIYGAPGGRVGEETGYVAEKGKA
CCCCCEEEEEECCHHHCEEEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA