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The map label for this gene is 182677928

Identifier: 182677928

GI number: 182677928

Start: 1073128

End: 1074465

Strand: Direct

Name: 182677928

Synonym: Bind_0937

Alternate gene names: NA

Gene position: 1073128-1074465 (Clockwise)

Preceding gene: 182677927

Following gene: 182677929

Centisome position: 25.73

GC content: 59.19

Gene sequence:

>1338_bases
ATGACCGATATGACTTTTCCCGGCCTGGATCGACAGGGATCGGAGACGGTCAAATTGCTCCGCGATGCGGCTTTGCCTCT
GCCGGATCCCGATGCGGAACAAGATTTCGGGACTCTCTTCGATCGTTTTGCCGGCGCGCGTGTCGTGCTGCTTGGCGAGG
CGACGCATGGCAGTTCCGAATTCTATCGCGCCCGTGCCGCGATCACGCGGCGGCTGATCGAACGTCACGGTTTCAGCATT
GTCATCGTCGAGGCCGATTGGCCCGATGCCAATCGTATCGACCGTTATGTTCGCCATCGCGGGCCGGGCCAATATGATAA
GGATTCCTTCGCCCGTTTCCCGACCTGGATGTGGCGCAATGAAGAGGTCGGCGCCTTCGTCACGTGGATGCGTCAGCATA
ATGAAGCTTTGCCGATGGAACAGCGGGCCGAATTTCGCGGGCTCGATGTCTATTCCCTGCATGCCTCCGTACAAGCCGTG
CTCACTTATCTTGATCGTGTCGATCCGGCGGCGGCCGCAATCGCGCGCAAGCGTTATGGCTGCTTGTCGGCTTGGCACAT
GGACCCGGCCTGGTATGGCCGGGCGGTCCTGCGCGGCACTCATGACAGTTGCGAGGATGCCGTCGTCGCCCAATTAAAAA
CCATGCTTGACCGTGAACTCGATGCCACGGCGAAGGATGGCGAGGATCTTTTTGATGCTGTGCAGAATGCGCGGATCGTG
CGTGCCGCCGAGACCTATTATCGGATCATGTATCGCGGCTCGACGGAATCCTGGAATCTGCGCGACCGGCATATGTTCGA
GACATTGCAATATGTGATGAAAGCCCGCGGCCCGGAAACCAAGGCTGTGGTCTGGGCGCATAATTCCCATATCGGCAATG
CGGCGGCGACCGTGATGGGCTGGCAGGGCGAATTCAATATCGGCGAATTCTGCAAGACGGCCTATGGCGACGACGCCGTG
TCGATCGGCTTCGGCACCGATCGCGGTACGGTTGCTGCCGCCGACGATTGGGACGGCCCTATGCGCATCAAGAACGTGCT
GCCGGCAAGGCTCGATTCCTACGAATATCTGTTTTTGAAGGCCGGTATGCCGCGCTCATTGACCGAGCTGCGGGGGCATG
GACGGGGTGCCTTGCGAGAGGCTCTGACGCAGTCTCGGCTCGAACGGGCGATCGGCGTTATCTATCGCCCTGATACGGAA
TTCCATAGCCATTATTTCGAAGCTGTCCTGCCCGATCAGTTCGATGCCTATGTCTGGTTCGAGGAAACGAAAGCCGTGAC
ACCCTTGCCGAGCAGCCGCCCGCATGGCGTGCCGGAGACTTATCCTTTTGGTGTGTGA

Upstream 100 bases:

>100_bases
CAAGAAGCTGGGAGAATGGTGCCTAAATCGGACTGAATGCATCATCCAAGCTTTAACTTGGACACGATCTCTCCCGCGTT
CGCCAACGATGGAGGTTCGT

Downstream 100 bases:

>100_bases
TTCCCTTTCCGGAGACGGAAGAGGGATTTGAACCCTGTGGGCTGCCAGACTCACACACAGCCCGCCGGGTTCAAAAGTGT
ATGTCGTCGCGATTAATTCA

Product: erythromycin esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTDMTFPGLDRQGSETVKLLRDAALPLPDPDAEQDFGTLFDRFAGARVVLLGEATHGSSEFYRARAAITRRLIERHGFSI
VIVEADWPDANRIDRYVRHRGPGQYDKDSFARFPTWMWRNEEVGAFVTWMRQHNEALPMEQRAEFRGLDVYSLHASVQAV
LTYLDRVDPAAAAIARKRYGCLSAWHMDPAWYGRAVLRGTHDSCEDAVVAQLKTMLDRELDATAKDGEDLFDAVQNARIV
RAAETYYRIMYRGSTESWNLRDRHMFETLQYVMKARGPETKAVVWAHNSHIGNAAATVMGWQGEFNIGEFCKTAYGDDAV
SIGFGTDRGTVAAADDWDGPMRIKNVLPARLDSYEYLFLKAGMPRSLTELRGHGRGALREALTQSRLERAIGVIYRPDTE
FHSHYFEAVLPDQFDAYVWFEETKAVTPLPSSRPHGVPETYPFGV

Sequences:

>Translated_445_residues
MTDMTFPGLDRQGSETVKLLRDAALPLPDPDAEQDFGTLFDRFAGARVVLLGEATHGSSEFYRARAAITRRLIERHGFSI
VIVEADWPDANRIDRYVRHRGPGQYDKDSFARFPTWMWRNEEVGAFVTWMRQHNEALPMEQRAEFRGLDVYSLHASVQAV
LTYLDRVDPAAAAIARKRYGCLSAWHMDPAWYGRAVLRGTHDSCEDAVVAQLKTMLDRELDATAKDGEDLFDAVQNARIV
RAAETYYRIMYRGSTESWNLRDRHMFETLQYVMKARGPETKAVVWAHNSHIGNAAATVMGWQGEFNIGEFCKTAYGDDAV
SIGFGTDRGTVAAADDWDGPMRIKNVLPARLDSYEYLFLKAGMPRSLTELRGHGRGALREALTQSRLERAIGVIYRPDTE
FHSHYFEAVLPDQFDAYVWFEETKAVTPLPSSRPHGVPETYPFGV
>Mature_444_residues
TDMTFPGLDRQGSETVKLLRDAALPLPDPDAEQDFGTLFDRFAGARVVLLGEATHGSSEFYRARAAITRRLIERHGFSIV
IVEADWPDANRIDRYVRHRGPGQYDKDSFARFPTWMWRNEEVGAFVTWMRQHNEALPMEQRAEFRGLDVYSLHASVQAVL
TYLDRVDPAAAAIARKRYGCLSAWHMDPAWYGRAVLRGTHDSCEDAVVAQLKTMLDRELDATAKDGEDLFDAVQNARIVR
AAETYYRIMYRGSTESWNLRDRHMFETLQYVMKARGPETKAVVWAHNSHIGNAAATVMGWQGEFNIGEFCKTAYGDDAVS
IGFGTDRGTVAAADDWDGPMRIKNVLPARLDSYEYLFLKAGMPRSLTELRGHGRGALREALTQSRLERAIGVIYRPDTEF
HSHYFEAVLPDQFDAYVWFEETKAVTPLPSSRPHGVPETYPFGV

Specific function: Unknown

COG id: COG2312

COG function: function code R; Erythromycin esterase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007815
- InterPro:   IPR000836 [H]

Pfam domain/function: PF05139 Erythro_esteras; PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 50415; Mature: 50284

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDMTFPGLDRQGSETVKLLRDAALPLPDPDAEQDFGTLFDRFAGARVVLLGEATHGSSE
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHH
FYRARAAITRRLIERHGFSIVIVEADWPDANRIDRYVRHRGPGQYDKDSFARFPTWMWRN
HHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCEECC
EEVGAFVTWMRQHNEALPMEQRAEFRGLDVYSLHASVQAVLTYLDRVDPAAAAIARKRYG
CCCHHHHHHHHHCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHC
CLSAWHMDPAWYGRAVLRGTHDSCEDAVVAQLKTMLDRELDATAKDGEDLFDAVQNARIV
CHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHH
RAAETYYRIMYRGSTESWNLRDRHMFETLQYVMKARGPETKAVVWAHNSHIGNAAATVMG
HHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHEEEE
WQGEFNIGEFCKTAYGDDAVSIGFGTDRGTVAAADDWDGPMRIKNVLPARLDSYEYLFLK
CCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEEE
AGMPRSLTELRGHGRGALREALTQSRLERAIGVIYRPDTEFHSHYFEAVLPDQFDAYVWF
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHCCCCCCEEEEE
EETKAVTPLPSSRPHGVPETYPFGV
ECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDMTFPGLDRQGSETVKLLRDAALPLPDPDAEQDFGTLFDRFAGARVVLLGEATHGSSE
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHH
FYRARAAITRRLIERHGFSIVIVEADWPDANRIDRYVRHRGPGQYDKDSFARFPTWMWRN
HHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCEECC
EEVGAFVTWMRQHNEALPMEQRAEFRGLDVYSLHASVQAVLTYLDRVDPAAAAIARKRYG
CCCHHHHHHHHHCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHC
CLSAWHMDPAWYGRAVLRGTHDSCEDAVVAQLKTMLDRELDATAKDGEDLFDAVQNARIV
CHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHH
RAAETYYRIMYRGSTESWNLRDRHMFETLQYVMKARGPETKAVVWAHNSHIGNAAATVMG
HHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHEEEE
WQGEFNIGEFCKTAYGDDAVSIGFGTDRGTVAAADDWDGPMRIKNVLPARLDSYEYLFLK
CCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEEE
AGMPRSLTELRGHGRGALREALTQSRLERAIGVIYRPDTEFHSHYFEAVLPDQFDAYVWF
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHCCCCCCEEEEE
EETKAVTPLPSSRPHGVPETYPFGV
ECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]