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The map label for this gene is lgrC [H]

Identifier: 182677838

GI number: 182677838

Start: 949329

End: 952688

Strand: Direct

Name: lgrC [H]

Synonym: Bind_0845

Alternate gene names: 182677838

Gene position: 949329-952688 (Clockwise)

Preceding gene: 182677837

Following gene: 182677839

Centisome position: 22.76

GC content: 55.03

Gene sequence:

>3360_bases
ATGTTCGATGGTCTTTTCGGGCAGGAGTGTTCGGGATCCATGCCGACCTCAAACTCTGCGCTGATCCCGCGTGTGGCGCG
CGATGGTGATTTTCCGCTTTCCAATGCGCAGGCACGATTGTGGTTTTTTTGGCATCTGGAACCGCAAAGCGGTGCCTATG
GTCTGTCGAGGTCTGCTCGGCTGAAGGGGCGTCTGAATGAGGTTGCCGTGCAGCAGAGCGTTGATGCTCTGGTTGCGCGG
CATGAACTCTTGCGGACGACATTTGTCGAATGTGCCGATGGACGCGGTTTGCAACATATTCATGCTGTATTTTCGATACC
GCTCGAAGTCATCGACCTCGGCGGATTATCCGAGGCGGATCGGGAGGCGGAGGCTCATCGGCTGGCGGCGGCCGATGCAT
CGGCGCCGTTTGATCTTACGACAGGTCCCTTGCTGCGGGTGAAACTGCTCCGGCTGGGGGATGAGGATCATATTCTTCTG
GTGACGTTGCACCGCATTATCTCCGATCGTCAATCGCTGGATATCCTGTTCAACGAATTTGCGGTATTTTACGCGGCCTC
TATCCAGGGGCATGAGCCGAGGCTGCCCGAACAGTCGATCCAATATGTCGATTACGCTGTTTGGCAACGGGCATGGCTGG
AAGCCGGGGAGGGCGATCGCCAGCTTGCTTATTGGCGCGGAAAGCTTGGAGACGAGCAACCGCTTCTGGAACTCCCCTTG
GACCATCCAAGACCTGCGGAGCAGAACGGCCGCGGAGCTATCCACCTCTTTGCGATTGATGGTGATCTGACTGAGCGATT
GCGGCATATCGGTCAAAGCCGAAATGCGAGTCTGTCGGTGGTGCTGCTGGCGGCGTTCAATGGGCTGCTCTATCGTTATA
CAGGACAGCGCGATCTCCGGGTCGGTGTCCCGGTGACAAATCGCCATCGGCCCGAGACGAAAGATCTGATTGGATGTTTT
GCGAACACGCTCGTCCTGCGGACGGAGCTTGATGGTCATTGGAGTTTTACGCGCCTCATTGAGGCAGTCCGTGACACCTT
GCTGGAGGCTCGGGACTATCAGGATTTGCCATTCGAGCAGCTGGTGCAGGCCTTGCAGCCGGAACGAAGCCTCAGTCATA
GTCCTTTGTTCCAGGTTCAATTCAATTCTGTTTCGCGGAGGGTTCCAGGCGAGCTCGTTGAACTGTCTGATCTTTTGATC
GAAGGTGTCGCAGAAGCGAAGACGATGATAAGGGTCGATCTCTCGCTCGATATTGTCGAGACCGCGACGGGAAACGGAGA
GCAGGAAGGACTTTCCTGCGGCTTGACTTATGCGGAAGATCTCTTCGATGCGATGACGATCGAACGTCTTGCATCGCATT
GGCGACACGTGCTTGAGGCGCTTGCGGATGCGCCGGATCGCACGATCGGAAGTGTCGATATTCTGGACGCGGATGAGCGC
AGACAAATTCTTGAAGAATGGGGCTGCGGGGAGAGTGTCCCGCAAAGCGGGAAATGTCTGCATGAGTTGATTGAGGCGCA
GGTGCGGGAGCAACCCGATGCTGTCGCGGTCCTCTATGAGGGTCAGAGCTTCACCTATGGAGAATTGAACGCCAAGGCCA
ATCAATTGGCGCACCATCTGCGCGAGCTTGGCGTGGGACCCGATGTTCTGGTCGGGATTGCCGTCGAGCCGTCGCTTGAC
ATGGTCATTGGCTTGGTGGGGATTTTGAAAGCGGGCGGCGCTTATGTGCCCCTTGATCCGAACTATCCCGAGGACCGCCT
CGCTTATATGATCGAAAACAGCGGGATCGGGCTGCTGTTGACTCAGGAACCGTTGCTGGGCGCCTTTGGCTGGCTGGGTC
GGGAACCAAAGCCTGGCATCGGATCCAATCCGATGATTTTCTGCCTTGACCGTGATTGGCTCAAAGTATCGGCCTATCCC
ACGGAGGATTTGCCGAATATCACCAATCCGCAAAATCTCATTTATTGCATCTACACTTCTGGCTCGACAGGAAGGCCTAA
AGGCGCAGACAATTACCACGCAAGTTTTGTAAATCTCGTTGGCTGGTATTTCAGTGAGAGCGAGAGGGCACATCGAAAAG
AAAGAGTGATTCTTGCCAGTTCACTGAGTTTCGATCTCACGCAGAAAAATGTGTTGGGGACGCTGGCCGCTGGCGGAACA
CTCATCGTCCCATTAGGGACGTTGATGGATACAGACCACTTCGTCGCAGCGTTAACACGGTTTAAGCCGACACGCTTGAA
TTGTACACCTTCAGCATATCACGTCATCTCAAAGTATGTGACGGAACACACGCTTTCCTTGGTGGTTCTCGGCGGGGAGC
CTATTGACGCAACCTTAGCTGCGCATTTATCGAAACAAAATATCGACTTGATGAATTCGTATGGGCCGACGGAATGTGCT
GATGTCGCCATATCTTATTTGAACGCGGCGGGTTCGGAACAAACCGATATTCCGCTGGGGAAGCCGCTTCCAAATATACA
AATCTATATTTTAGATGCTGATCTCAATCTTGTTCCCGCTGGTGTTGCGGGTGAATTGTATATAGCGGGTATCAGCCTCG
GGCGCGGATATCACGGGCGTCCCGATCTGACTGCGGAGCGTTTTATCGCCAATCCTTTTGCGAAGGAGACCGGGGCTCGG
ATGTACCGGACCGGAGACCTGGCGCGGTGGCGGTCCGATGGTAACGTGGACTATATTGGCCGTGTTGACCATCAGGTGAA
GATCCGCGGATTCAGGATTGAGCTTGGCGAGATCGAGGCCGCCTTGCTGCGCTATGAGGGCGTGCGTGAGGCCATCGTTC
TCGTGCGTGATGCTGCCGGCGGCAAGCAACTCATTGGCTATGTGGTGGGAGCGGATGAGCGGGGGGATCTCGAAAGCCGC
CTTCGAAATCATCTGAAAAGTTCTCTCCCCGATTATATGGTGCCTGCACGGATCGTCGTGCTTGAGAAAATGCCTTTAAC
GGTCAATGGCAAGGTCGATCGCCAGCGGTTACCTGCGCCAAAACCTCTTATTGTTTCAGCGGGTTTCGCCACCAATCTGT
CATCCACACAGAAGCTTCTGGTGGAAATCTGGCGCGAGGTTTTGGGGCTCGACGCGGTTCCAGCCGAGGTTAATTTTTTC
GATCTTGGCGGAAATTCCTTGCAACTCATTGCCGTGCACGCCCAAATCGAATCCAAGTTGCAGCGCAAATTTCCTCTCGT
CACGCTCTTTCAGCATTCGACCATCACGGACCTGGCTCATTTTCTCGATAACAAGGGGCAGGAGGTTTCGTCATCCATCG
ACGCCGCCCGGGCGCGTGCCTTGCAGCGGAGCCGGAGTCTCGGCAGATTCCAGCAAAAAGTGGGGAGGAAGACACCATAG

Upstream 100 bases:

>100_bases
TCTGCCACTCCTATCAGGATTTTGCCTTGGGAGCGCCCTCATTAGGTTGGTCGCATGGGAAAGGCTGGGTATCTTGTTGG
TTTTTGCTCTTGGGTGCTGA

Downstream 100 bases:

>100_bases
ATATCCGCAAGGGAGCTGTTTCGTACAATTCCCGGACATTTTTGCAAAATCCTATGGAAGAGCGGGTGGGAATCCCAGTG
GAATTATCGAGGATATGTCT

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1119; Mature: 1119

Protein sequence:

>1119_residues
MFDGLFGQECSGSMPTSNSALIPRVARDGDFPLSNAQARLWFFWHLEPQSGAYGLSRSARLKGRLNEVAVQQSVDALVAR
HELLRTTFVECADGRGLQHIHAVFSIPLEVIDLGGLSEADREAEAHRLAAADASAPFDLTTGPLLRVKLLRLGDEDHILL
VTLHRIISDRQSLDILFNEFAVFYAASIQGHEPRLPEQSIQYVDYAVWQRAWLEAGEGDRQLAYWRGKLGDEQPLLELPL
DHPRPAEQNGRGAIHLFAIDGDLTERLRHIGQSRNASLSVVLLAAFNGLLYRYTGQRDLRVGVPVTNRHRPETKDLIGCF
ANTLVLRTELDGHWSFTRLIEAVRDTLLEARDYQDLPFEQLVQALQPERSLSHSPLFQVQFNSVSRRVPGELVELSDLLI
EGVAEAKTMIRVDLSLDIVETATGNGEQEGLSCGLTYAEDLFDAMTIERLASHWRHVLEALADAPDRTIGSVDILDADER
RQILEEWGCGESVPQSGKCLHELIEAQVREQPDAVAVLYEGQSFTYGELNAKANQLAHHLRELGVGPDVLVGIAVEPSLD
MVIGLVGILKAGGAYVPLDPNYPEDRLAYMIENSGIGLLLTQEPLLGAFGWLGREPKPGIGSNPMIFCLDRDWLKVSAYP
TEDLPNITNPQNLIYCIYTSGSTGRPKGADNYHASFVNLVGWYFSESERAHRKERVILASSLSFDLTQKNVLGTLAAGGT
LIVPLGTLMDTDHFVAALTRFKPTRLNCTPSAYHVISKYVTEHTLSLVVLGGEPIDATLAAHLSKQNIDLMNSYGPTECA
DVAISYLNAAGSEQTDIPLGKPLPNIQIYILDADLNLVPAGVAGELYIAGISLGRGYHGRPDLTAERFIANPFAKETGAR
MYRTGDLARWRSDGNVDYIGRVDHQVKIRGFRIELGEIEAALLRYEGVREAIVLVRDAAGGKQLIGYVVGADERGDLESR
LRNHLKSSLPDYMVPARIVVLEKMPLTVNGKVDRQRLPAPKPLIVSAGFATNLSSTQKLLVEIWREVLGLDAVPAEVNFF
DLGGNSLQLIAVHAQIESKLQRKFPLVTLFQHSTITDLAHFLDNKGQEVSSSIDAARARALQRSRSLGRFQQKVGRKTP

Sequences:

>Translated_1119_residues
MFDGLFGQECSGSMPTSNSALIPRVARDGDFPLSNAQARLWFFWHLEPQSGAYGLSRSARLKGRLNEVAVQQSVDALVAR
HELLRTTFVECADGRGLQHIHAVFSIPLEVIDLGGLSEADREAEAHRLAAADASAPFDLTTGPLLRVKLLRLGDEDHILL
VTLHRIISDRQSLDILFNEFAVFYAASIQGHEPRLPEQSIQYVDYAVWQRAWLEAGEGDRQLAYWRGKLGDEQPLLELPL
DHPRPAEQNGRGAIHLFAIDGDLTERLRHIGQSRNASLSVVLLAAFNGLLYRYTGQRDLRVGVPVTNRHRPETKDLIGCF
ANTLVLRTELDGHWSFTRLIEAVRDTLLEARDYQDLPFEQLVQALQPERSLSHSPLFQVQFNSVSRRVPGELVELSDLLI
EGVAEAKTMIRVDLSLDIVETATGNGEQEGLSCGLTYAEDLFDAMTIERLASHWRHVLEALADAPDRTIGSVDILDADER
RQILEEWGCGESVPQSGKCLHELIEAQVREQPDAVAVLYEGQSFTYGELNAKANQLAHHLRELGVGPDVLVGIAVEPSLD
MVIGLVGILKAGGAYVPLDPNYPEDRLAYMIENSGIGLLLTQEPLLGAFGWLGREPKPGIGSNPMIFCLDRDWLKVSAYP
TEDLPNITNPQNLIYCIYTSGSTGRPKGADNYHASFVNLVGWYFSESERAHRKERVILASSLSFDLTQKNVLGTLAAGGT
LIVPLGTLMDTDHFVAALTRFKPTRLNCTPSAYHVISKYVTEHTLSLVVLGGEPIDATLAAHLSKQNIDLMNSYGPTECA
DVAISYLNAAGSEQTDIPLGKPLPNIQIYILDADLNLVPAGVAGELYIAGISLGRGYHGRPDLTAERFIANPFAKETGAR
MYRTGDLARWRSDGNVDYIGRVDHQVKIRGFRIELGEIEAALLRYEGVREAIVLVRDAAGGKQLIGYVVGADERGDLESR
LRNHLKSSLPDYMVPARIVVLEKMPLTVNGKVDRQRLPAPKPLIVSAGFATNLSSTQKLLVEIWREVLGLDAVPAEVNFF
DLGGNSLQLIAVHAQIESKLQRKFPLVTLFQHSTITDLAHFLDNKGQEVSSSIDAARARALQRSRSLGRFQQKVGRKTP
>Mature_1119_residues
MFDGLFGQECSGSMPTSNSALIPRVARDGDFPLSNAQARLWFFWHLEPQSGAYGLSRSARLKGRLNEVAVQQSVDALVAR
HELLRTTFVECADGRGLQHIHAVFSIPLEVIDLGGLSEADREAEAHRLAAADASAPFDLTTGPLLRVKLLRLGDEDHILL
VTLHRIISDRQSLDILFNEFAVFYAASIQGHEPRLPEQSIQYVDYAVWQRAWLEAGEGDRQLAYWRGKLGDEQPLLELPL
DHPRPAEQNGRGAIHLFAIDGDLTERLRHIGQSRNASLSVVLLAAFNGLLYRYTGQRDLRVGVPVTNRHRPETKDLIGCF
ANTLVLRTELDGHWSFTRLIEAVRDTLLEARDYQDLPFEQLVQALQPERSLSHSPLFQVQFNSVSRRVPGELVELSDLLI
EGVAEAKTMIRVDLSLDIVETATGNGEQEGLSCGLTYAEDLFDAMTIERLASHWRHVLEALADAPDRTIGSVDILDADER
RQILEEWGCGESVPQSGKCLHELIEAQVREQPDAVAVLYEGQSFTYGELNAKANQLAHHLRELGVGPDVLVGIAVEPSLD
MVIGLVGILKAGGAYVPLDPNYPEDRLAYMIENSGIGLLLTQEPLLGAFGWLGREPKPGIGSNPMIFCLDRDWLKVSAYP
TEDLPNITNPQNLIYCIYTSGSTGRPKGADNYHASFVNLVGWYFSESERAHRKERVILASSLSFDLTQKNVLGTLAAGGT
LIVPLGTLMDTDHFVAALTRFKPTRLNCTPSAYHVISKYVTEHTLSLVVLGGEPIDATLAAHLSKQNIDLMNSYGPTECA
DVAISYLNAAGSEQTDIPLGKPLPNIQIYILDADLNLVPAGVAGELYIAGISLGRGYHGRPDLTAERFIANPFAKETGAR
MYRTGDLARWRSDGNVDYIGRVDHQVKIRGFRIELGEIEAALLRYEGVREAIVLVRDAAGGKQLIGYVVGADERGDLESR
LRNHLKSSLPDYMVPARIVVLEKMPLTVNGKVDRQRLPAPKPLIVSAGFATNLSSTQKLLVEIWREVLGLDAVPAEVNFF
DLGGNSLQLIAVHAQIESKLQRKFPLVTLFQHSTITDLAHFLDNKGQEVSSSIDAARARALQRSRSLGRFQQKVGRKTP

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=544, Percent_Identity=23.8970588235294, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI45580730, Length=680, Percent_Identity=22.7941176470588, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI122937307, Length=376, Percent_Identity=26.5957446808511, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI38505220, Length=375, Percent_Identity=25.0666666666667, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI42544132, Length=384, Percent_Identity=24.7395833333333, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI115511026, Length=365, Percent_Identity=23.8356164383562, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI58082049, Length=390, Percent_Identity=24.1025641025641, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI157311624, Length=390, Percent_Identity=23.0769230769231, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI157311622, Length=390, Percent_Identity=23.0769230769231, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI38524616, Length=554, Percent_Identity=23.1046931407942, Blast_Score=77, Evalue=7e-14,
Organism=Escherichia coli, GI1786801, Length=1082, Percent_Identity=28.8354898336414, Blast_Score=319, Evalue=5e-88,
Organism=Escherichia coli, GI1786810, Length=520, Percent_Identity=24.6153846153846, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1788107, Length=549, Percent_Identity=24.2258652094718, Blast_Score=97, Evalue=9e-21,
Organism=Escherichia coli, GI145693145, Length=539, Percent_Identity=23.5621521335807, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1790505, Length=568, Percent_Identity=22.3591549295775, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17550940, Length=1114, Percent_Identity=21.0951526032316, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17556356, Length=554, Percent_Identity=25.4512635379061, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994690, Length=572, Percent_Identity=24.1258741258741, Blast_Score=107, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71994694, Length=572, Percent_Identity=24.1258741258741, Blast_Score=107, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71994703, Length=557, Percent_Identity=24.2369838420108, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560308, Length=597, Percent_Identity=23.1155778894472, Blast_Score=90, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17559526, Length=393, Percent_Identity=24.1730279898219, Blast_Score=90, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560140, Length=499, Percent_Identity=22.0440881763527, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531443, Length=541, Percent_Identity=21.81146025878, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985884, Length=360, Percent_Identity=24.4444444444444, Blast_Score=74, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=912, Percent_Identity=25.109649122807, Blast_Score=224, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6319264, Length=564, Percent_Identity=23.4042553191489, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323182, Length=637, Percent_Identity=24.0188383045526, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319699, Length=519, Percent_Identity=20.4238921001927, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24648676, Length=610, Percent_Identity=30.4918032786885, Blast_Score=219, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24581924, Length=529, Percent_Identity=24.1965973534972, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24582852, Length=507, Percent_Identity=23.6686390532544, Blast_Score=79, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 123425; Mature: 123425

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDGLFGQECSGSMPTSNSALIPRVARDGDFPLSNAQARLWFFWHLEPQSGAYGLSRSAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHH
LKGRLNEVAVQQSVDALVARHELLRTTFVECADGRGLQHIHAVFSIPLEVIDLGGLSEAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHEEECCCCCHHH
REAEAHRLAAADASAPFDLTTGPLLRVKLLRLGDEDHILLVTLHRIISDRQSLDILFNEF
HHHHHHHHHHCCCCCCCCCCCCCHHEEEEEEECCCCCEEEEEHHHHHCCCHHHHHHHHHH
AVFYAASIQGHEPRLPEQSIQYVDYAVWQRAWLEAGEGDRQLAYWRGKLGDEQPLLELPL
HHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCC
DHPRPAEQNGRGAIHLFAIDGDLTERLRHIGQSRNASLSVVLLAAFNGLLYRYTGQRDLR
CCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEECCCCCEE
VGVPVTNRHRPETKDLIGCFANTLVLRTELDGHWSFTRLIEAVRDTLLEARDYQDLPFEQ
ECCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
LVQALQPERSLSHSPLFQVQFNSVSRRVPGELVELSDLLIEGVAEAKTMIRVDLSLDIVE
HHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEEEEEEEEE
TATGNGEQEGLSCGLTYAEDLFDAMTIERLASHWRHVLEALADAPDRTIGSVDILDADER
ECCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHH
RQILEEWGCGESVPQSGKCLHELIEAQVREQPDAVAVLYEGQSFTYGELNAKANQLAHHL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHHHHHH
RELGVGPDVLVGIAVEPSLDMVIGLVGILKAGGAYVPLDPNYPEDRLAYMIENSGIGLLL
HHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHEEEEEECCCEEEEE
TQEPLLGAFGWLGREPKPGIGSNPMIFCLDRDWLKVSAYPTEDLPNITNPQNLIYCIYTS
ECCCHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCCCCCEEEEEEEC
GSTGRPKGADNYHASFVNLVGWYFSESERAHRKERVILASSLSFDLTQKNVLGTLAAGGT
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCCE
LIVPLGTLMDTDHFVAALTRFKPTRLNCTPSAYHVISKYVTEHTLSLVVLGGEPIDATLA
EEEECHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHH
AHLSKQNIDLMNSYGPTECADVAISYLNAAGSEQTDIPLGKPLPNIQIYILDADLNLVPA
HHHHHCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCEECC
GVAGELYIAGISLGRGYHGRPDLTAERFIANPFAKETGARMYRTGDLARWRSDGNVDYIG
CCCCEEEEEEEEECCCCCCCCCCCHHHHHCCCHHHHHCCCEEECCCHHHHCCCCCEEEEE
RVDHQVKIRGFRIELGEIEAALLRYEGVREAIVLVRDAAGGKQLIGYVVGADERGDLESR
CCCCEEEEEEEEEEHHHHHHHHHHHHCHHEEEEEEECCCCCCEEEEEEECCCCCCCHHHH
LRNHLKSSLPDYMVPARIVVLEKMPLTVNGKVDRQRLPAPKPLIVSAGFATNLSSTQKLL
HHHHHHHCCCCHHCCCEEEEEECCCEEECCCCCHHHCCCCCCEEEECCCCCCCHHHHHHH
VEIWREVLGLDAVPAEVNFFDLGGNSLQLIAVHAQIESKLQRKFPLVTLFQHSTITDLAH
HHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHCCCEEEEECCCHHHHHHH
FLDNKGQEVSSSIDAARARALQRSRSLGRFQQKVGRKTP
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFDGLFGQECSGSMPTSNSALIPRVARDGDFPLSNAQARLWFFWHLEPQSGAYGLSRSAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHH
LKGRLNEVAVQQSVDALVARHELLRTTFVECADGRGLQHIHAVFSIPLEVIDLGGLSEAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHEEECCCCCHHH
REAEAHRLAAADASAPFDLTTGPLLRVKLLRLGDEDHILLVTLHRIISDRQSLDILFNEF
HHHHHHHHHHCCCCCCCCCCCCCHHEEEEEEECCCCCEEEEEHHHHHCCCHHHHHHHHHH
AVFYAASIQGHEPRLPEQSIQYVDYAVWQRAWLEAGEGDRQLAYWRGKLGDEQPLLELPL
HHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCC
DHPRPAEQNGRGAIHLFAIDGDLTERLRHIGQSRNASLSVVLLAAFNGLLYRYTGQRDLR
CCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEECCCCCEE
VGVPVTNRHRPETKDLIGCFANTLVLRTELDGHWSFTRLIEAVRDTLLEARDYQDLPFEQ
ECCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
LVQALQPERSLSHSPLFQVQFNSVSRRVPGELVELSDLLIEGVAEAKTMIRVDLSLDIVE
HHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEEEEEEEEE
TATGNGEQEGLSCGLTYAEDLFDAMTIERLASHWRHVLEALADAPDRTIGSVDILDADER
ECCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHH
RQILEEWGCGESVPQSGKCLHELIEAQVREQPDAVAVLYEGQSFTYGELNAKANQLAHHL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHHHHHH
RELGVGPDVLVGIAVEPSLDMVIGLVGILKAGGAYVPLDPNYPEDRLAYMIENSGIGLLL
HHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHEEEEEECCCEEEEE
TQEPLLGAFGWLGREPKPGIGSNPMIFCLDRDWLKVSAYPTEDLPNITNPQNLIYCIYTS
ECCCHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCCCCCEEEEEEEC
GSTGRPKGADNYHASFVNLVGWYFSESERAHRKERVILASSLSFDLTQKNVLGTLAAGGT
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCCE
LIVPLGTLMDTDHFVAALTRFKPTRLNCTPSAYHVISKYVTEHTLSLVVLGGEPIDATLA
EEEECHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHH
AHLSKQNIDLMNSYGPTECADVAISYLNAAGSEQTDIPLGKPLPNIQIYILDADLNLVPA
HHHHHCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCEECC
GVAGELYIAGISLGRGYHGRPDLTAERFIANPFAKETGARMYRTGDLARWRSDGNVDYIG
CCCCEEEEEEEEECCCCCCCCCCCHHHHHCCCHHHHHCCCEEECCCHHHHCCCCCEEEEE
RVDHQVKIRGFRIELGEIEAALLRYEGVREAIVLVRDAAGGKQLIGYVVGADERGDLESR
CCCCEEEEEEEEEEHHHHHHHHHHHHCHHEEEEEEECCCCCCEEEEEEECCCCCCCHHHH
LRNHLKSSLPDYMVPARIVVLEKMPLTVNGKVDRQRLPAPKPLIVSAGFATNLSSTQKLL
HHHHHHHCCCCHHCCCEEEEEECCCEEECCCCCHHHCCCCCCEEEECCCCCCCHHHHHHH
VEIWREVLGLDAVPAEVNFFDLGGNSLQLIAVHAQIESKLQRKFPLVTLFQHSTITDLAH
HHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHCCCEEEEECCCHHHHHHH
FLDNKGQEVSSSIDAARARALQRSRSLGRFQQKVGRKTP
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA