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The map label for this gene is ftsA [H]

Identifier: 182677690

GI number: 182677690

Start: 779746

End: 781062

Strand: Direct

Name: ftsA [H]

Synonym: Bind_0697

Alternate gene names: 182677690

Gene position: 779746-781062 (Clockwise)

Preceding gene: 182677689

Following gene: 182677691

Centisome position: 18.7

GC content: 62.79

Gene sequence:

>1317_bases
ATGAATCCTCCCACGCTCGCTCCTCGCCTCCGTCCTTTGCCGAGCCGCAAGAGCACGATTCTGTCTGTGCTCGATATTGG
CACGTCCAAGATTGTCAGCCTGATCGCCAGGCTCAACCCTACCGAAGCCTCCGAGACCTTGCGGGGGCGCACGCATCGCT
GTCGCATTCTCGGCATCGGCCATCAGCGTTCGCGCGGGATGAAGGGTGGCACTGTTGTCGACATGCTGGAAGCCGAGAGC
GCGATCCGGCTTGCTGTTGACGCAGCCGAACGCATGGCCGGCGTGCAGGTCGAAAGCGTCATCATCAATGTGACGGGCGG
CCGGCTCGCCTCGCAATTGTTCGACGCCAAGGTGGGTATTGTCTCCCGCGCGGTCGGCGAAAACGATGTGCATCGCGTGC
TTGAGGCCTGCGCGCATCGCGGCGCCCAGCAGGGGCGAGCAGTGCTGCATGCCTTGCCCATGGGGTTTTCTCTCGGCGAG
ACACGGTCGATCCGCGATCCGCGCGGCATGATCGGCGATGAACTCGGCGCGGCCATGCATGTCCTGAGCTGCGATGCCGC
TGCTGCCCGCAATCTGATGCTGGCGGTCGAGCGTTGTCATCTCAGCGTCGATGCCATGGTCGCCACCCCTTATGCGAGCG
GTCTCTCGGCTCTAGTTGATGATGAAGCCGAACTCGGCACGGCGGTCATCGATATGGGGGGCGGCACGACCTCGATCGGC
CTCTTTTCCGGCGGCTCGCTCGTGCATGTCGATGCTTTCGCGGTTGGTGGCCATCATGTCACCATGGATGTCGCGCGCGG
CCTCAACATGCGCCTTGCCGATGCCGAACGGCTTAAAACTCTGCATGGCGCTTGTCTCGCCGCGAGCTCCGATGAGCGCG
ACATGATTGGTGTGACGCAGGCCGATGATGATGGTGATCACGCGACGCATGTGCCGAAATCGCATCTCGTGCGGATTATC
AAGCCGAGGATCGAGGAAATTCTGGAACTGGTCCGCGATCGTCTGCATGCCGCCGGGTTTCCGGCCCATGCCGGCCGCAG
GCTGGTGCTCACCGGCGGCGCCTGTCAATTGACAGGCCTGCCGGAAATGACCAAACGGATCGTCTCCGGTCAGGTTCGAA
TCGGACGCCCGCTCGGCGTTCAAGGGCTCCCGGATGTTGCGAAAAGCCCGGCCTTTTCGGCTTCTGTCGGCCTGATGATC
TATCCGCAGGTCAGCGGGATCGAACATTTTCGGCCGGGCGTCGGGCATGCCCCGACGGATGCTGGTTCCGATCGTTATAT
GCGGCGGGTCGGGCGCTGGCTGCGCAATAGTTTCTGA

Upstream 100 bases:

>100_bases
GCCCGGACGCATGGTCGCGCATCTTTCCGCCGAAGCCGCCGCCGAACGCGCTGAAATGCTGGCGCATAAAACCGCCAAGA
AGAAGGGGGGCTAGCGTCTC

Downstream 100 bases:

>100_bases
CATTTCTCGCCGGGGAATTTCGGTTTTTCGGCGTGAAAAGAAGATTTTCAAAACCGGGTTTTTCGAGACGTGGCGGCGGC
ACGAAAAACCCGAACAATTC

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNPPTLAPRLRPLPSRKSTILSVLDIGTSKIVSLIARLNPTEASETLRGRTHRCRILGIGHQRSRGMKGGTVVDMLEAES
AIRLAVDAAERMAGVQVESVIINVTGGRLASQLFDAKVGIVSRAVGENDVHRVLEACAHRGAQQGRAVLHALPMGFSLGE
TRSIRDPRGMIGDELGAAMHVLSCDAAAARNLMLAVERCHLSVDAMVATPYASGLSALVDDEAELGTAVIDMGGGTTSIG
LFSGGSLVHVDAFAVGGHHVTMDVARGLNMRLADAERLKTLHGACLAASSDERDMIGVTQADDDGDHATHVPKSHLVRII
KPRIEEILELVRDRLHAAGFPAHAGRRLVLTGGACQLTGLPEMTKRIVSGQVRIGRPLGVQGLPDVAKSPAFSASVGLMI
YPQVSGIEHFRPGVGHAPTDAGSDRYMRRVGRWLRNSF

Sequences:

>Translated_438_residues
MNPPTLAPRLRPLPSRKSTILSVLDIGTSKIVSLIARLNPTEASETLRGRTHRCRILGIGHQRSRGMKGGTVVDMLEAES
AIRLAVDAAERMAGVQVESVIINVTGGRLASQLFDAKVGIVSRAVGENDVHRVLEACAHRGAQQGRAVLHALPMGFSLGE
TRSIRDPRGMIGDELGAAMHVLSCDAAAARNLMLAVERCHLSVDAMVATPYASGLSALVDDEAELGTAVIDMGGGTTSIG
LFSGGSLVHVDAFAVGGHHVTMDVARGLNMRLADAERLKTLHGACLAASSDERDMIGVTQADDDGDHATHVPKSHLVRII
KPRIEEILELVRDRLHAAGFPAHAGRRLVLTGGACQLTGLPEMTKRIVSGQVRIGRPLGVQGLPDVAKSPAFSASVGLMI
YPQVSGIEHFRPGVGHAPTDAGSDRYMRRVGRWLRNSF
>Mature_438_residues
MNPPTLAPRLRPLPSRKSTILSVLDIGTSKIVSLIARLNPTEASETLRGRTHRCRILGIGHQRSRGMKGGTVVDMLEAES
AIRLAVDAAERMAGVQVESVIINVTGGRLASQLFDAKVGIVSRAVGENDVHRVLEACAHRGAQQGRAVLHALPMGFSLGE
TRSIRDPRGMIGDELGAAMHVLSCDAAAARNLMLAVERCHLSVDAMVATPYASGLSALVDDEAELGTAVIDMGGGTTSIG
LFSGGSLVHVDAFAVGGHHVTMDVARGLNMRLADAERLKTLHGACLAASSDERDMIGVTQADDDGDHATHVPKSHLVRII
KPRIEEILELVRDRLHAAGFPAHAGRRLVLTGGACQLTGLPEMTKRIVSGQVRIGRPLGVQGLPDVAKSPAFSASVGLMI
YPQVSGIEHFRPGVGHAPTDAGSDRYMRRVGRWLRNSF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=422, Percent_Identity=31.9905213270142, Blast_Score=218, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 46476; Mature: 46476

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPTLAPRLRPLPSRKSTILSVLDIGTSKIVSLIARLNPTEASETLRGRTHRCRILGIG
CCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECC
HQRSRGMKGGTVVDMLEAESAIRLAVDAAERMAGVQVESVIINVTGGRLASQLFDAKVGI
CHHCCCCCCCCCEEHHHHCCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHH
VSRAVGENDVHRVLEACAHRGAQQGRAVLHALPMGFSLGETRSIRDPRGMIGDELGAAMH
HHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VLSCDAAAARNLMLAVERCHLSVDAMVATPYASGLSALVDDEAELGTAVIDMGGGTTSIG
HHHCCHHHHHHHHHHHHHHHCEEEHEEECCHHHHHHHHHCCCHHHCEEEEECCCCCEEEE
LFSGGSLVHVDAFAVGGHHVTMDVARGLNMRLADAERLKTLHGACLAASSDERDMIGVTQ
EECCCCEEEEEEEEECCEEEEEHHHCCCCEEECCHHHHHHHHHHHEECCCCCCCEEEEEC
ADDDGDHATHVPKSHLVRIIKPRIEEILELVRDRLHAAGFPAHAGRRLVLTGGACQLTGL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCC
PEMTKRIVSGQVRIGRPLGVQGLPDVAKSPAFSASVGLMIYPQVSGIEHFRPGVGHAPTD
HHHHHHHHCCCEEECCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCC
AGSDRYMRRVGRWLRNSF
CCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPPTLAPRLRPLPSRKSTILSVLDIGTSKIVSLIARLNPTEASETLRGRTHRCRILGIG
CCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECC
HQRSRGMKGGTVVDMLEAESAIRLAVDAAERMAGVQVESVIINVTGGRLASQLFDAKVGI
CHHCCCCCCCCCEEHHHHCCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHH
VSRAVGENDVHRVLEACAHRGAQQGRAVLHALPMGFSLGETRSIRDPRGMIGDELGAAMH
HHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VLSCDAAAARNLMLAVERCHLSVDAMVATPYASGLSALVDDEAELGTAVIDMGGGTTSIG
HHHCCHHHHHHHHHHHHHHHCEEEHEEECCHHHHHHHHHCCCHHHCEEEEECCCCCEEEE
LFSGGSLVHVDAFAVGGHHVTMDVARGLNMRLADAERLKTLHGACLAASSDERDMIGVTQ
EECCCCEEEEEEEEECCEEEEEHHHCCCCEEECCHHHHHHHHHHHEECCCCCCCEEEEEC
ADDDGDHATHVPKSHLVRIIKPRIEEILELVRDRLHAAGFPAHAGRRLVLTGGACQLTGL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCC
PEMTKRIVSGQVRIGRPLGVQGLPDVAKSPAFSASVGLMIYPQVSGIEHFRPGVGHAPTD
HHHHHHHHCCCEEECCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCC
AGSDRYMRRVGRWLRNSF
CCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]