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The map label for this gene is pdhS [H]

Identifier: 182677673

GI number: 182677673

Start: 759807

End: 761993

Strand: Direct

Name: pdhS [H]

Synonym: Bind_0680

Alternate gene names: 182677673

Gene position: 759807-761993 (Clockwise)

Preceding gene: 182677672

Following gene: 182677674

Centisome position: 18.22

GC content: 60.27

Gene sequence:

>2187_bases
ATGGACAAGTTTTGCTTCGCGCCGGGTGTCTCTGAGACCACGATCGCGCCGTTCCTGGAAATTTTCGGGCCGGGACCATG
GGATGAGGGGGCCATTCTCGGATTCGAGCAGGCAGAGGATCATCAAGGGGCCGGGCTTTTCGTCGCTTTCGCCAGCCAGG
CCATGCTGGACCTCTTCGGTGTGACGGCGCTCGAAATTCTGCGGCACCGGTTTTTCCAGCCGGCCGATCCCGGCTTTGGA
CGACTGGCGGAAATTGCCGCTGATGCCACGCAATCCTTGCGGCTGGCGCGGTTGCGGTTTTTCGTGAATGGCAAGAGCAT
TGTGCGGACGTTTTGGTGCGGCACGCTCGAACGGCAGGGGCGGCGCATGACCCTCATTGCCGAGGCGCAAGCCTATCGCT
CGCGCCTCGTGTTGCAGCAACAGGCACGCCCGCGGCAGGAGCCGGTTGTGGCTTTGCTGGCAGACCCTCTGCCGGATGAT
ATGGCCATCGTGCGGGCGGATCTGGCGCGACGGTTTCCGGGCGAGCGGCCTTTGCGGTTTCTTTGGCGCACGGATGGGGA
GCACCGTCTCGTCGAAATCGGTTCCCTCCTCGCCGAGGTGACGGGACTCTTGCCAGAAAAATGGGTCGGAGGACCTTTTT
CTTCCTTGTTGCGGGCCTTCGATCCGACGGCCGCGACCATGACCGACTGGATTTTCGCCGCGTGCGAAGGGGTGGACGAT
CTCAAACTTGCTTGGCCGATCGAGGGACGCACGGTTGCCGTCGATATTGCCCTTGGGGGACTTCCGCGGCGCGACGCCGC
TGGCAATTTTGCGGGTTATCAGGGCTTTGGCTTGATTCATAAGGATCGGCTCACGGCGCGCCTGTTGGAACCTCAGGAGG
AAGAGGAAGGACAAGCGCTTTCGCCGGTTTTGGCCGAGACCAGGGGAGTGATCGATGCCGGAGAGCCTGTTTCGGCCTTC
CCACGGACGGATGAAACAGCGCAAGGACCGGTTGAAGGGGAAAGAGCCGCGCGCCAGGCGCTCGAAGCGCGCATGCATCG
CTACGAGAGTGAAGTCCGGGAACTGCATGCCATTCTTGATACGGCGACGGATGGTGTCGCCGTTCTCGATGCGGAAGGCA
GGATTCTCACCCTGAACCGTTCGGGCGAGGCCTTGTTCGGCTATGATCGGGGCGAGGTTCTTAGCCAGCCGTTCACCATG
CTGATCGCCCCGGCGAGCCGCCGCCGGGCCATGGATTATTTCGAGGGCGTGAAAACCGGAGGCGTCCTCAGTCTGTTGAA
TGATGGGCGTGAGATTTTTGGCCTCGCCCGCCAGGGCGGCACAATTCCGATCTTCATGACGCTCGGTCGGATTGGCCTCT
TCGTCACAGCGGAGACGATGCCGGAACAAGGCGTTTTTGAGAAATATTGCGTGCTGCTGCGCGATATGAGCCATTGGAAA
AAAATCGAGCGCGAACTCGAGGCGGCGCGCAAGGAAGCCGAACGGGCGAGTACCTTGAAATCGGATTTCCTCGCCAAGGT
CAGCCATGAGATTCGGACACCCTTGAATGCCATTCTCGGATTTACCGAAGTCATCATGGATGAACGGTTTGGGCCGATCG
GCAATGAGCGTTACAAGGATTATCTGAAGGACATTCATATGTCCGGCACCCTTGTGATGAGCCTTGTGAACGATCTTCTC
GATCTCTCGAAGATCGAGGCTGGCAAGATGGACCTGGACTTCGTCGCCGTTGACACCAATCAGATCATCGCCGACTGCGT
CTCGCTCATGCAGCCCCAGGCCAATCGCGAGGGTATTTTGGTGCGCCTTGCGCTGGCGCCGGCCTTGCCGCCGTTGCTCG
CCGATGAGAGATCCTTGCGCCAGATCGTGCTCAATCTTCTGTCCAATGCGGTGAAATTCACCGAGCCCGGCGGCCAGGTG
ATGGTGGCGACGAAATTGATGGAAGACGGCAAGACTCTGATCCGCATCCGCGATACGGGGGCGGGCATGTCGGAGGAGGA
GATTGGGATTGCGCTGGAGCCGTTTCGCCAGCTCTCGACCTCGCGTTCCAATCAGGGCACGGGTCTCGGCCTGCCGCTGA
CCAAAGCCTTGGTCGAGGCCAATCGCGCATCCTTTTCGATCTCCAGCAAGAAGCAGGAAGGCACTGTCGTGGAGATCCTG
TTTCCCTCGGCGCGCGCCTTGGTTTGA

Upstream 100 bases:

>100_bases
CCCCGTGCGGTGAAGCCATTAGGGTTTTATTAACGCTCCCGCGCGGGAGCAGGCTCCCCACGCCGGTGCCAGCGGCGGCG
ATTTGAGAAAGCCTGGACTC

Downstream 100 bases:

>100_bases
TGCCCTCGCAGGAACAGGCGCGGGGGGCGCTTGCGATGCAATGGCGATCATTGCCGAATAATCCTGTGCGAATAATCGTG
TGAGAGTCACGGAACGCTTT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MDKFCFAPGVSETTIAPFLEIFGPGPWDEGAILGFEQAEDHQGAGLFVAFASQAMLDLFGVTALEILRHRFFQPADPGFG
RLAEIAADATQSLRLARLRFFVNGKSIVRTFWCGTLERQGRRMTLIAEAQAYRSRLVLQQQARPRQEPVVALLADPLPDD
MAIVRADLARRFPGERPLRFLWRTDGEHRLVEIGSLLAEVTGLLPEKWVGGPFSSLLRAFDPTAATMTDWIFAACEGVDD
LKLAWPIEGRTVAVDIALGGLPRRDAAGNFAGYQGFGLIHKDRLTARLLEPQEEEEGQALSPVLAETRGVIDAGEPVSAF
PRTDETAQGPVEGERAARQALEARMHRYESEVRELHAILDTATDGVAVLDAEGRILTLNRSGEALFGYDRGEVLSQPFTM
LIAPASRRRAMDYFEGVKTGGVLSLLNDGREIFGLARQGGTIPIFMTLGRIGLFVTAETMPEQGVFEKYCVLLRDMSHWK
KIERELEAARKEAERASTLKSDFLAKVSHEIRTPLNAILGFTEVIMDERFGPIGNERYKDYLKDIHMSGTLVMSLVNDLL
DLSKIEAGKMDLDFVAVDTNQIIADCVSLMQPQANREGILVRLALAPALPPLLADERSLRQIVLNLLSNAVKFTEPGGQV
MVATKLMEDGKTLIRIRDTGAGMSEEEIGIALEPFRQLSTSRSNQGTGLGLPLTKALVEANRASFSISSKKQEGTVVEIL
FPSARALV

Sequences:

>Translated_728_residues
MDKFCFAPGVSETTIAPFLEIFGPGPWDEGAILGFEQAEDHQGAGLFVAFASQAMLDLFGVTALEILRHRFFQPADPGFG
RLAEIAADATQSLRLARLRFFVNGKSIVRTFWCGTLERQGRRMTLIAEAQAYRSRLVLQQQARPRQEPVVALLADPLPDD
MAIVRADLARRFPGERPLRFLWRTDGEHRLVEIGSLLAEVTGLLPEKWVGGPFSSLLRAFDPTAATMTDWIFAACEGVDD
LKLAWPIEGRTVAVDIALGGLPRRDAAGNFAGYQGFGLIHKDRLTARLLEPQEEEEGQALSPVLAETRGVIDAGEPVSAF
PRTDETAQGPVEGERAARQALEARMHRYESEVRELHAILDTATDGVAVLDAEGRILTLNRSGEALFGYDRGEVLSQPFTM
LIAPASRRRAMDYFEGVKTGGVLSLLNDGREIFGLARQGGTIPIFMTLGRIGLFVTAETMPEQGVFEKYCVLLRDMSHWK
KIERELEAARKEAERASTLKSDFLAKVSHEIRTPLNAILGFTEVIMDERFGPIGNERYKDYLKDIHMSGTLVMSLVNDLL
DLSKIEAGKMDLDFVAVDTNQIIADCVSLMQPQANREGILVRLALAPALPPLLADERSLRQIVLNLLSNAVKFTEPGGQV
MVATKLMEDGKTLIRIRDTGAGMSEEEIGIALEPFRQLSTSRSNQGTGLGLPLTKALVEANRASFSISSKKQEGTVVEIL
FPSARALV
>Mature_728_residues
MDKFCFAPGVSETTIAPFLEIFGPGPWDEGAILGFEQAEDHQGAGLFVAFASQAMLDLFGVTALEILRHRFFQPADPGFG
RLAEIAADATQSLRLARLRFFVNGKSIVRTFWCGTLERQGRRMTLIAEAQAYRSRLVLQQQARPRQEPVVALLADPLPDD
MAIVRADLARRFPGERPLRFLWRTDGEHRLVEIGSLLAEVTGLLPEKWVGGPFSSLLRAFDPTAATMTDWIFAACEGVDD
LKLAWPIEGRTVAVDIALGGLPRRDAAGNFAGYQGFGLIHKDRLTARLLEPQEEEEGQALSPVLAETRGVIDAGEPVSAF
PRTDETAQGPVEGERAARQALEARMHRYESEVRELHAILDTATDGVAVLDAEGRILTLNRSGEALFGYDRGEVLSQPFTM
LIAPASRRRAMDYFEGVKTGGVLSLLNDGREIFGLARQGGTIPIFMTLGRIGLFVTAETMPEQGVFEKYCVLLRDMSHWK
KIERELEAARKEAERASTLKSDFLAKVSHEIRTPLNAILGFTEVIMDERFGPIGNERYKDYLKDIHMSGTLVMSLVNDLL
DLSKIEAGKMDLDFVAVDTNQIIADCVSLMQPQANREGILVRLALAPALPPLLADERSLRQIVLNLLSNAVKFTEPGGQV
MVATKLMEDGKTLIRIRDTGAGMSEEEIGIALEPFRQLSTSRSNQGTGLGLPLTKALVEANRASFSISSKKQEGTVVEIL
FPSARALV

Specific function: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Localizes at the old pole of dividing cells. Colocalizes with divK (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=35.4430379746835, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=32.6612903225806, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=33.4630350194552, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=26.7195767195767, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=34.7107438016529, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI1788713, Length=259, Percent_Identity=30.5019305019305, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=270, Percent_Identity=22.962962962963, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=28, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=23.5059760956175, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=238, Percent_Identity=25.6302521008403, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=23.728813559322, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790346, Length=211, Percent_Identity=26.0663507109005, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80030; Mature: 80030

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFCFAPGVSETTIAPFLEIFGPGPWDEGAILGFEQAEDHQGAGLFVAFASQAMLDLFG
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEHHHHHHHHHHHH
VTALEILRHRFFQPADPGFGRLAEIAADATQSLRLARLRFFVNGKSIVRTFWCGTLERQG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCC
RRMTLIAEAQAYRSRLVLQQQARPRQEPVVALLADPLPDDMAIVRADLARRFPGERPLRF
CEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
LWRTDGEHRLVEIGSLLAEVTGLLPEKWVGGPFSSLLRAFDPTAATMTDWIFAACEGVDD
EECCCCCHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCC
LKLAWPIEGRTVAVDIALGGLPRRDAAGNFAGYQGFGLIHKDRLTARLLEPQEEEEGQAL
CEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCHH
SPVLAETRGVIDAGEPVSAFPRTDETAQGPVEGERAARQALEARMHRYESEVRELHAILD
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TATDGVAVLDAEGRILTLNRSGEALFGYDRGEVLSQPFTMLIAPASRRRAMDYFEGVKTG
CCCCCEEEEECCCEEEEEECCCCEEECCCCHHHHCCCCEEEECCCHHHHHHHHHHCCCCC
GVLSLLNDGREIFGLARQGGTIPIFMTLGRIGLFVTAETMPEQGVFEKYCVLLRDMSHWK
CHHHHHHCCHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
KIERELEAARKEAERASTLKSDFLAKVSHEIRTPLNAILGFTEVIMDERFGPIGNERYKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
YLKDIHMSGTLVMSLVNDLLDLSKIEAGKMDLDFVAVDTNQIIADCVSLMQPQANREGIL
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCEE
VRLALAPALPPLLADERSLRQIVLNLLSNAVKFTEPGGQVMVATKLMEDGKTLIRIRDTG
EEEEECCCCCCHHCCHHHHHHHHHHHHHHHHEECCCCCCEEEEEHHHHCCCEEEEEECCC
AGMSEEEIGIALEPFRQLSTSRSNQGTGLGLPLTKALVEANRASFSISSKKQEGTVVEIL
CCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEEE
FPSARALV
CCCHHCCC
>Mature Secondary Structure
MDKFCFAPGVSETTIAPFLEIFGPGPWDEGAILGFEQAEDHQGAGLFVAFASQAMLDLFG
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEHHHHHHHHHHHH
VTALEILRHRFFQPADPGFGRLAEIAADATQSLRLARLRFFVNGKSIVRTFWCGTLERQG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCC
RRMTLIAEAQAYRSRLVLQQQARPRQEPVVALLADPLPDDMAIVRADLARRFPGERPLRF
CEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
LWRTDGEHRLVEIGSLLAEVTGLLPEKWVGGPFSSLLRAFDPTAATMTDWIFAACEGVDD
EECCCCCHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCC
LKLAWPIEGRTVAVDIALGGLPRRDAAGNFAGYQGFGLIHKDRLTARLLEPQEEEEGQAL
CEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCHH
SPVLAETRGVIDAGEPVSAFPRTDETAQGPVEGERAARQALEARMHRYESEVRELHAILD
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TATDGVAVLDAEGRILTLNRSGEALFGYDRGEVLSQPFTMLIAPASRRRAMDYFEGVKTG
CCCCCEEEEECCCEEEEEECCCCEEECCCCHHHHCCCCEEEECCCHHHHHHHHHHCCCCC
GVLSLLNDGREIFGLARQGGTIPIFMTLGRIGLFVTAETMPEQGVFEKYCVLLRDMSHWK
CHHHHHHCCHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
KIERELEAARKEAERASTLKSDFLAKVSHEIRTPLNAILGFTEVIMDERFGPIGNERYKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
YLKDIHMSGTLVMSLVNDLLDLSKIEAGKMDLDFVAVDTNQIIADCVSLMQPQANREGIL
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCEE
VRLALAPALPPLLADERSLRQIVLNLLSNAVKFTEPGGQVMVATKLMEDGKTLIRIRDTG
EEEEECCCCCCHHCCHHHHHHHHHHHHHHHHEECCCCCCEEEEEHHHHCCCEEEEEECCC
AGMSEEEIGIALEPFRQLSTSRSNQGTGLGLPLTKALVEANRASFSISSKKQEGTVVEIL
CCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEEE
FPSARALV
CCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA