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The map label for this gene is qor [H]

Identifier: 182677667

GI number: 182677667

Start: 755044

End: 756012

Strand: Direct

Name: qor [H]

Synonym: Bind_0674

Alternate gene names: 182677667

Gene position: 755044-756012 (Clockwise)

Preceding gene: 182677665

Following gene: 182677668

Centisome position: 18.11

GC content: 61.2

Gene sequence:

>969_bases
ATGGACAAGAAGGTAGAATTGACCGCCGTGGGTGGCATCGACAAGCTCAGGGTCGCTGACTGCATCCCTCAACAGCCAGC
ACCCGGCGAACTGCGCATCCGCCACGAAGGTATCGGCGTCAACTTCATCGACATATACCACCGGACTGGGCTTTATCCCT
TGCCGCTTCCCGCGATCCTGGGTGTCGAAGGGGCCGGCGTTGTCGAAGCGGTTGGAGCTGACGTCGCTGATTTCCATGTC
GGTGATCGTATCGCTTATGCCGGCATCCCAGGCGCCTACGCGGCGACGCGCCTCCTGCCGGCTTGGCGTGCTACCAAATT
GCCGGACGACATTAGCGCCAAGACGGCAGCCGCTTCGTTCCTCCGCGGACTGACGGCGCATATGCTTCTGACCCGCACCT
ATCCGGTTGGGAGGGGAACGACGTTGCTCATTCATGCCGGTGCGGGCGGCCTCGGCATCACGCTGACGAGGTGGGCCAAG
CAGCTTGACTGCACCGTCATCGCGACCGTCGGATCGATCGAGAAAGCAGACATTGCACGCGCGAACGGTGCGGATCACGT
CATTATCGGTCGTGAGACAGATATCGTTGCCGAGGTCAGTCGTCTGACCAACGCTAAGGGCGTCGATTACGCGATCGATG
GCATAGGCGGCGAAACTCTGCGCAAAACGCTCGGTTGCGTCAGGCGTTTCGGGGTCGTGGCCTCCATCGGGCAAGTGGCG
GGACCGATCCCTCCTGTCCCCGTTGAAGAGCTTGGCCCCATTCGTTCGCTGTCGCTATCGCGTCCGAGCGTCATGGCCTA
TACGACGGAACAGGACGCCTATCGTTTCGCAACGCAGGCCGTCATCACAGCGATCCGCCAAGGTATCATTCCAAGCGCTG
GCCATGAGTATGGCCTGACGAACGCCGCGCAGGCGCAAAGCGACCTTGAAGCGGGAAAGACGACTGGAAGCCTCGTGCTC
GTCCCTTAA

Upstream 100 bases:

>100_bases
CCAGTTCATCGGTTAAAATATTCACATTAAAAGTCAGATTTTAGGGAATTTTCTATCGGAATGCCAGATGCCAGACTCCG
GGCAGAAACGGAGATAAACA

Downstream 100 bases:

>100_bases
CCGGAGCCTGACGGATGCAGTGGCGGTCATCAGCCGTGGCGAAGGTCGTGAACGATCTGAAGCAGCACCTCTGGAAATAA
AATAAACATATAAGCTATAG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MDKKVELTAVGGIDKLRVADCIPQQPAPGELRIRHEGIGVNFIDIYHRTGLYPLPLPAILGVEGAGVVEAVGADVADFHV
GDRIAYAGIPGAYAATRLLPAWRATKLPDDISAKTAAASFLRGLTAHMLLTRTYPVGRGTTLLIHAGAGGLGITLTRWAK
QLDCTVIATVGSIEKADIARANGADHVIIGRETDIVAEVSRLTNAKGVDYAIDGIGGETLRKTLGCVRRFGVVASIGQVA
GPIPPVPVEELGPIRSLSLSRPSVMAYTTEQDAYRFATQAVITAIRQGIIPSAGHEYGLTNAAQAQSDLEAGKTTGSLVL
VP

Sequences:

>Translated_322_residues
MDKKVELTAVGGIDKLRVADCIPQQPAPGELRIRHEGIGVNFIDIYHRTGLYPLPLPAILGVEGAGVVEAVGADVADFHV
GDRIAYAGIPGAYAATRLLPAWRATKLPDDISAKTAAASFLRGLTAHMLLTRTYPVGRGTTLLIHAGAGGLGITLTRWAK
QLDCTVIATVGSIEKADIARANGADHVIIGRETDIVAEVSRLTNAKGVDYAIDGIGGETLRKTLGCVRRFGVVASIGQVA
GPIPPVPVEELGPIRSLSLSRPSVMAYTTEQDAYRFATQAVITAIRQGIIPSAGHEYGLTNAAQAQSDLEAGKTTGSLVL
VP
>Mature_322_residues
MDKKVELTAVGGIDKLRVADCIPQQPAPGELRIRHEGIGVNFIDIYHRTGLYPLPLPAILGVEGAGVVEAVGADVADFHV
GDRIAYAGIPGAYAATRLLPAWRATKLPDDISAKTAAASFLRGLTAHMLLTRTYPVGRGTTLLIHAGAGGLGITLTRWAK
QLDCTVIATVGSIEKADIARANGADHVIIGRETDIVAEVSRLTNAKGVDYAIDGIGGETLRKTLGCVRRFGVVASIGQVA
GPIPPVPVEELGPIRSLSLSRPSVMAYTTEQDAYRFATQAVITAIRQGIIPSAGHEYGLTNAAQAQSDLEAGKTTGSLVL
VP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI24308257, Length=232, Percent_Identity=31.4655172413793, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI18379349, Length=235, Percent_Identity=32.3404255319149, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI194239674, Length=313, Percent_Identity=28.1150159744409, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI13236495, Length=313, Percent_Identity=28.1150159744409, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI28557745, Length=322, Percent_Identity=27.639751552795, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI194239676, Length=190, Percent_Identity=32.1052631578947, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=27.4096385542169, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=27.4096385542169, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=37.6146788990826, Blast_Score=209, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17507255, Length=215, Percent_Identity=29.7674418604651, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=322, Percent_Identity=31.6770186335404, Blast_Score=170, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33695; Mature: 33695

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKVELTAVGGIDKLRVADCIPQQPAPGELRIRHEGIGVNFIDIYHRTGLYPLPLPAIL
CCCEEEEEEECCCCHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEHHHCCCCCCCCHHHH
GVEGAGVVEAVGADVADFHVGDRIAYAGIPGAYAATRLLPAWRATKLPDDISAKTAAASF
CCCCCCHHHHHCCCHHHEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LRGLTAHMLLTRTYPVGRGTTLLIHAGAGGLGITLTRWAKQLDCTVIATVGSIEKADIAR
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCEEEEEECCCCCHHHHHH
ANGADHVIIGRETDIVAEVSRLTNAKGVDYAIDGIGGETLRKTLGCVRRFGVVASIGQVA
CCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GPIPPVPVEELGPIRSLSLSRPSVMAYTTEQDAYRFATQAVITAIRQGIIPSAGHEYGLT
CCCCCCCHHHCCCCHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NAAQAQSDLEAGKTTGSLVLVP
CHHHHHHHHHCCCCCCCEEEEC
>Mature Secondary Structure
MDKKVELTAVGGIDKLRVADCIPQQPAPGELRIRHEGIGVNFIDIYHRTGLYPLPLPAIL
CCCEEEEEEECCCCHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEHHHCCCCCCCCHHHH
GVEGAGVVEAVGADVADFHVGDRIAYAGIPGAYAATRLLPAWRATKLPDDISAKTAAASF
CCCCCCHHHHHCCCHHHEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LRGLTAHMLLTRTYPVGRGTTLLIHAGAGGLGITLTRWAKQLDCTVIATVGSIEKADIAR
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCEEEEEECCCCCHHHHHH
ANGADHVIIGRETDIVAEVSRLTNAKGVDYAIDGIGGETLRKTLGCVRRFGVVASIGQVA
CCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GPIPPVPVEELGPIRSLSLSRPSVMAYTTEQDAYRFATQAVITAIRQGIIPSAGHEYGLT
CCCCCCCHHHCCCCHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NAAQAQSDLEAGKTTGSLVLVP
CHHHHHHHHHCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]