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The map label for this gene is 182677653

Identifier: 182677653

GI number: 182677653

Start: 742586

End: 743302

Strand: Direct

Name: 182677653

Synonym: Bind_0660

Alternate gene names: NA

Gene position: 742586-743302 (Clockwise)

Preceding gene: 182677652

Following gene: 182677654

Centisome position: 17.81

GC content: 62.48

Gene sequence:

>717_bases
GTGGCGAGGCTTCTTTCCCGCACTTGGTGCGCGCTTGCAGCGGCCTTGCTCGCAGTCTCGGTTATGAGCGCCAGCCCGCT
GCCCGCCGAGGCGCAAAATTGCGGATCGCGATCTTGCGCGGCGAGCGGTGAACCAGGCGACTTCGATTTCTATCTTCTCT
CCCTGTCCTGGTCGGCGACCTATTGCGCCAACCATCGGGCGGATGGCGCGCGCAGGCCGTCCTCCCAATGCCAGGATGGA
GGCGGGCAGGGATTCGTTGTCCACGGCCTATGGCCGCAATATGAGCAGGGCTATCCATCCGCCTGTCAGCCCTCAGCGCC
TGCACCGTCCTGGTTCATTTTGCGTGAGACGGGGGATCTTTATCCGGATCCCGGACTCGCCCGGCATGAATGGCGCCAGC
ATGGGTCCTGTTCCGGCAAAACGCCCAGCGCCTATTTCGATGATGTGCGCCGGGCGCGCGATATGGTCACCATTCCCGAA
ATCTTTCGCGGTGACGGGGCAGGGTGGGTAAATTTGACAGGCAATGAGATCAAACGCCGGTTTGTCGAGGCCAATCCGGG
GTTGCGCGCTGATATGCTGACCCTGACGTGCCGTGGCTCCCTGTTGAGTGAGGTCCGTGTCTGTCTCACCCGCGATCTGC
GCGGTTTCCGGCCTTGTCCTCAGGCTATGCCGCAGGCCTGTCGCGCCTATCAAATCTCCGTGCCGAAGCCGTTCTGA

Upstream 100 bases:

>100_bases
GGTTGGGCATGGATGTCGGCGTCGAATGGTGTATTACCGGGCTCGACCGCAGCAATGGTTTCGGAGCAGATTGCCAAAGC
ATCCAGCCCTGAGGTTCGGC

Downstream 100 bases:

>100_bases
ACCTTGAACTATCGCCACGATTTTCACGCCGGCAATTTCGCCGATGTGTTCAAACACATCATCCTGGCGCGCGCCTTGAC
CTATTTGGGGCGAAAGCCAA

Product: ribonuclease T2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MARLLSRTWCALAAALLAVSVMSASPLPAEAQNCGSRSCAASGEPGDFDFYLLSLSWSATYCANHRADGARRPSSQCQDG
GGQGFVVHGLWPQYEQGYPSACQPSAPAPSWFILRETGDLYPDPGLARHEWRQHGSCSGKTPSAYFDDVRRARDMVTIPE
IFRGDGAGWVNLTGNEIKRRFVEANPGLRADMLTLTCRGSLLSEVRVCLTRDLRGFRPCPQAMPQACRAYQISVPKPF

Sequences:

>Translated_238_residues
MARLLSRTWCALAAALLAVSVMSASPLPAEAQNCGSRSCAASGEPGDFDFYLLSLSWSATYCANHRADGARRPSSQCQDG
GGQGFVVHGLWPQYEQGYPSACQPSAPAPSWFILRETGDLYPDPGLARHEWRQHGSCSGKTPSAYFDDVRRARDMVTIPE
IFRGDGAGWVNLTGNEIKRRFVEANPGLRADMLTLTCRGSLLSEVRVCLTRDLRGFRPCPQAMPQACRAYQISVPKPF
>Mature_237_residues
ARLLSRTWCALAAALLAVSVMSASPLPAEAQNCGSRSCAASGEPGDFDFYLLSLSWSATYCANHRADGARRPSSQCQDGG
GQGFVVHGLWPQYEQGYPSACQPSAPAPSWFILRETGDLYPDPGLARHEWRQHGSCSGKTPSAYFDDVRRARDMVTIPEI
FRGDGAGWVNLTGNEIKRRFVEANPGLRADMLTLTCRGSLLSEVRVCLTRDLRGFRPCPQAMPQACRAYQISVPKPF

Specific function: One of the few RNases that cleave the phosphodiester bond between any two nucleotide. Shows a preference for adenylic acid [H]

COG id: COG3719

COG function: function code J; Ribonuclease I

Gene ontology:

Cell location: Periplasm. Cytoplasm. Note=An RNase I-like form (periplasmic) and RNase I*-like form (cytoplasmic) appear to be isoforms apparently encoded by the same gene. The cytoplasmic form is less active towards natural polymer RNA [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase T2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001568
- InterPro:   IPR018188 [H]

Pfam domain/function: PF00445 Ribonuclease_T2 [H]

EC number: NA

Molecular weight: Translated: 26019; Mature: 25887

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00530 RNASE_T2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLLSRTWCALAAALLAVSVMSASPLPAEAQNCGSRSCAASGEPGDFDFYLLSLSWSAT
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHH
YCANHRADGARRPSSQCQDGGGQGFVVHGLWPQYEQGYPSACQPSAPAPSWFILRETGDL
HHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCHHCCCCCCCCCCCCCCCEEEEECCCCC
YPDPGLARHEWRQHGSCSGKTPSAYFDDVRRARDMVTIPEIFRGDGAGWVNLTGNEIKRR
CCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCEEEECHHHHHHH
FVEANPGLRADMLTLTCRGSLLSEVRVCLTRDLRGFRPCPQAMPQACRAYQISVPKPF
HHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEECCCCCC
>Mature Secondary Structure 
ARLLSRTWCALAAALLAVSVMSASPLPAEAQNCGSRSCAASGEPGDFDFYLLSLSWSAT
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHH
YCANHRADGARRPSSQCQDGGGQGFVVHGLWPQYEQGYPSACQPSAPAPSWFILRETGDL
HHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCHHCCCCCCCCCCCCCCCEEEEECCCCC
YPDPGLARHEWRQHGSCSGKTPSAYFDDVRRARDMVTIPEIFRGDGAGWVNLTGNEIKRR
CCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCEEEECHHHHHHH
FVEANPGLRADMLTLTCRGSLLSEVRVCLTRDLRGFRPCPQAMPQACRAYQISVPKPF
HHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685334 [H]