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The map label for this gene is dnaA [H]

Identifier: 17548159

GI number: 17548159

Start: 3714708

End: 3716276

Strand: Reverse

Name: dnaA [H]

Synonym: RSc3442

Alternate gene names: 17548159

Gene position: 3716276-3714708 (Counterclockwise)

Preceding gene: NA

Following gene: 17548158

Centisome position: 100.0

GC content: 65.2

Gene sequence:

>1569_bases
ATGCAGGATTTTTGGCATGCGGCGTCCGCCCAGCTCGAGAGCGAGCTGACTCCGCAACAATTCAAGACGTGGATCAAGCC
GCTGACGCCGCTGTCATTCGACGAGCAGGCGTGCATGCTGCGGATTGCCGCGCCTAACCGTTTCAAGCTCGACTGGGTCA
AGAGCCAGTTTTCGGGCCGCATTCAGTCGCTCGCGTGCGACTACTGGGAGATGCAGGTCGACGTGCAGTTCGTGCTCGAC
CCGACCGCCGGCCAGCGCCAGGCCGCCATGCAGCCGGCACTGGCCCCGATGCCGATGCAGCCGCTGGCTGCGCAAACGAT
GCAGGCCCAGGCTGTGCCGCGCGAAGCGCCGGCCCGCCCCACAATGGCGCCCTACCGCGAAACCCCGATGGCCACGGCCG
CCCATGCGGCGGCCGACATCGACGTGCCCGTCATGGACGCCGCCGAGGCCAGCACCCAGTCGTACCGCGTGCCGGCACCG
GCCGCACCCGCCGTGATGGGTGGCCTGAGCGCACCGCCCGCCGCCCCGGTGGATGACACCGTGCACGAGCGCTCACGGCT
GAACCCCATCCTCACCTTCGACAACCTCGTCACCGGCAAGGCCAACCAGTTGGCGCGCGCGGCCGCCGTGCAGGTCGCCA
ACAACCCGGGCAAGTCGTACAACCCGCTGTACCTGTACGGCGGGGTGGGGCTGGGCAAGACCCACTTGATCCATGCCATC
GGCAACTTCATGCTGATGGAGAACCCGCGCGCGCGTATCCGCTACATCCACGCAGAACAGTACGTTTCCGACGTAGTGAA
GGCTTACCAGCGCAAGGCGTTCGACGACTTCAAGCGCTACTACCACTCGCTGGACCTGCTGCTGATCGACGACATCCAGT
TCTTCTCGGGCAAGAACCGCACGCAGGAAGAATTCTTCTATGCGTTCGAGGCGCTGATCGCCAACCGCGCGCAGGTCATC
ATCACCAGCGACACGTACCCGAAGGAGATCACCGGCATCGATGACCGGCTGATCTCGCGCTTCGACTCCGGCCTGACGGT
GGCCATCGAGCCGCCCGAGCTGGAGATGCGCGTCGCCATCCTGATGAAGAAGGCGCAGGCCGAGAACGTGACGGTGCCGG
AGGAGGTGGCCTTCTTCGTGGCCAAGCACCTGCGCTCGAACGTGCGCGAGCTGGAAGGCGCGCTGCGCAAGATCCTGGCG
TACTCGAACTTCCACGGCAAGGAGATCACCATCGAGGTCACGCGCGAGGCGCTCAAGGATCTGCTCACGGTGCAGAACCG
GCAGATCTCGGTGGAGAACATCCAGAAGACCTGCGCGGACTTCTACAACATCAAGGTCGCCGACATGTATTCCAAGAAGC
GGCCGGCCAACATCGCGCGCCCGCGCCAGATCGCCATGTACCTGGCCAAGGAGCTGACGCAGAAGAGCCTGCCGGAGATC
GGCGAGCTGTTCGGCGGACGCGACCACACCACGGTGCTGCACGCGGTACGCAAGATCGCCGACGAGCGCAGCAAGGACGC
CCAGCTCAACCACGAGCTGCACGTGCTGGAGCAGACGCTGAAGGGCTGA

Upstream 100 bases:

>100_bases
AGCCGCCCGACGCCCGGATACAACAGGCGCCCGGCGGCCGGCCCACCCGGGGGCGTCGACGACGACGCGCGTGGCGCCGG
GCAAACACCAAACGATAACG

Downstream 100 bases:

>100_bases
GCGCCCGAGCGATGACCGCGCAGTCGCCAGACCGCATGGCGGCGCCATCCGGCCCGAATCAGCCCTCCATCGGCGCCCGC
TCCAATGCGGGCGTCTTTTC

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MQDFWHAASAQLESELTPQQFKTWIKPLTPLSFDEQACMLRIAAPNRFKLDWVKSQFSGRIQSLACDYWEMQVDVQFVLD
PTAGQRQAAMQPALAPMPMQPLAAQTMQAQAVPREAPARPTMAPYRETPMATAAHAAADIDVPVMDAAEASTQSYRVPAP
AAPAVMGGLSAPPAAPVDDTVHERSRLNPILTFDNLVTGKANQLARAAAVQVANNPGKSYNPLYLYGGVGLGKTHLIHAI
GNFMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVI
ITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRVAILMKKAQAENVTVPEEVAFFVAKHLRSNVRELEGALRKILA
YSNFHGKEITIEVTREALKDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEI
GELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG

Sequences:

>Translated_522_residues
MQDFWHAASAQLESELTPQQFKTWIKPLTPLSFDEQACMLRIAAPNRFKLDWVKSQFSGRIQSLACDYWEMQVDVQFVLD
PTAGQRQAAMQPALAPMPMQPLAAQTMQAQAVPREAPARPTMAPYRETPMATAAHAAADIDVPVMDAAEASTQSYRVPAP
AAPAVMGGLSAPPAAPVDDTVHERSRLNPILTFDNLVTGKANQLARAAAVQVANNPGKSYNPLYLYGGVGLGKTHLIHAI
GNFMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVI
ITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRVAILMKKAQAENVTVPEEVAFFVAKHLRSNVRELEGALRKILA
YSNFHGKEITIEVTREALKDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEI
GELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
>Mature_522_residues
MQDFWHAASAQLESELTPQQFKTWIKPLTPLSFDEQACMLRIAAPNRFKLDWVKSQFSGRIQSLACDYWEMQVDVQFVLD
PTAGQRQAAMQPALAPMPMQPLAAQTMQAQAVPREAPARPTMAPYRETPMATAAHAAADIDVPVMDAAEASTQSYRVPAP
AAPAVMGGLSAPPAAPVDDTVHERSRLNPILTFDNLVTGKANQLARAAAVQVANNPGKSYNPLYLYGGVGLGKTHLIHAI
GNFMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVI
ITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRVAILMKKAQAENVTVPEEVAFFVAKHLRSNVRELEGALRKILA
YSNFHGKEITIEVTREALKDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEI
GELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=517, Percent_Identity=48.1624758220503, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 58492; Mature: 58492

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDFWHAASAQLESELTPQQFKTWIKPLTPLSFDEQACMLRIAAPNRFKLDWVKSQFSGR
CCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHCCH
IQSLACDYWEMQVDVQFVLDPTAGQRQAAMQPALAPMPMQPLAAQTMQAQAVPREAPARP
HHHHHCCCEEEEEEEEEEECCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
TMAPYRETPMATAAHAAADIDVPVMDAAEASTQSYRVPAPAAPAVMGGLSAPPAAPVDDT
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCHH
VHERSRLNPILTFDNLVTGKANQLARAAAVQVANNPGKSYNPLYLYGGVGLGKTHLIHAI
HHHHHHCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHHH
GNFMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKNR
HHHHEECCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCCCC
TQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRVAI
CHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCCHHHHHHHHCCCCEEEECCCCHHHHHHH
LMKKAQAENVTVPEEVAFFVAKHLRSNVRELEGALRKILAYSNFHGKEITIEVTREALKD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
LLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEI
HHHHCCCCCCHHHHHHHHHHHHCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
GELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
HHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDFWHAASAQLESELTPQQFKTWIKPLTPLSFDEQACMLRIAAPNRFKLDWVKSQFSGR
CCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHCCH
IQSLACDYWEMQVDVQFVLDPTAGQRQAAMQPALAPMPMQPLAAQTMQAQAVPREAPARP
HHHHHCCCEEEEEEEEEEECCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
TMAPYRETPMATAAHAAADIDVPVMDAAEASTQSYRVPAPAAPAVMGGLSAPPAAPVDDT
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCHH
VHERSRLNPILTFDNLVTGKANQLARAAAVQVANNPGKSYNPLYLYGGVGLGKTHLIHAI
HHHHHHCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHHH
GNFMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKNR
HHHHEECCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCCCC
TQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRVAI
CHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCCHHHHHHHHCCCCEEEECCCCHHHHHHH
LMKKAQAENVTVPEEVAFFVAKHLRSNVRELEGALRKILAYSNFHGKEITIEVTREALKD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
LLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEI
HHHHCCCCCCHHHHHHHHHHHHCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
GELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
HHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA