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The map label for this gene is cisA [H]

Identifier: 17547964

GI number: 17547964

Start: 3502812

End: 3504200

Strand: Direct

Name: cisA [H]

Synonym: RSc3247

Alternate gene names: 17547964

Gene position: 3502812-3504200 (Clockwise)

Preceding gene: 17547963

Following gene: 17547965

Centisome position: 94.25

GC content: 65.66

Gene sequence:

>1389_bases
ATGACCGGCGCCGTACAGATCGCCTCCGCCAAGCCGCGCAAACGCTGCGCGGTGTACTGCCGCGTCTCCACCGACGAGCG
GCTGGACCAGGAATTCAACTCCATCGATGCGCAGAAGGAAGCGGGACACGCCTTCATCGTCAGCCAGCGCTCCGAAGGCT
GGATCTCGGTGGCCGACGACTATGACGATCCTGGCTTCTCCGGCGGCAACACCGACCGGCCCGGCCTGCGGCGCCTGTTG
GCGGACATCGAGCGCGGACGCATCGACATCGTCGTGGTCTACAAGATCGACCGCCTGACCCGCAGCCTGGCCGACTTCTC
CAAGATGGTCGAGGTGTTCGAGCGCCACGACGTGTCGTTCGTGTCGGTAACCCAACAGTTCAACACCACCACGTCGATGG
GTAGGCTGATGCTCAACGTCCTGCTGTCCTTCGCGCAGTTCGAGCGCGAGGTCACCGGCGAGCGGATCCGCGACAAGATC
GCGGCGGCAAAGCGCAAGGGGCTGTGGATGGGCGGCGTGCCGCCTCTGGGCTACGACGTGCGTGATCGCCAACTGGTCGT
CAACGAAGTAGAGGCGACGGTGGTGCGGCGCATCTTCGAGGAGATGCTCACCATCGGGTCGCCCACGCAGATCGCCGCGC
GCCTGACCGCCGAAGGCATCACCACCAAGGCGTGGATCACGCAGGATGGCCGCGCCCGCTACGGCGCCGACATCGACAAG
AAGTACCTGTCCAAGCTGCTGCGCAACCGCATCTACCTGGGTGAGCTGTCGCACAAGGGAAGCTGGTATCCAGGCACGCA
TCCGGCCATCATTGGTGCCGAGTTGTGGCAGCGGGTCCATGCCGTACTGGCCAAGGATAGTTACGCCCGTTCGACCCACA
CCAAGGGGCTGTCGCGCACCGATGCGCTGCTGCGCGGTCTGCTGTACACGCCGTCTGGCGAGCGGATGTACCCGACCTAC
TCGCGCAAGAACGGCCGGCAGTACCGCTACTACGTGTCGAAGTCGGAGAGCCGCTTCGGGGCGCCGGGCAAGCGCTACGA
GCGGCTGCCGGCACCGGAGATCGAGGGGGCCGTGGTCGCGCAAATCCGCACCGTGTTGACCAGTCCGGAGGCGGTGGCGG
CGGTAGTGCAGCACATCCAGCGCAACGGTGCCCAGGTCGATGAGGCATCAACGGTGATCGCGATGGGGCGACTCGATGAC
GTGTGGGAGCGGCTCTTCCCCACCGAGCGGCACCGCATCGCCAACCTGATGATCGAGCGCGTCGACCTCGTGAACGACGG
GGAGCGCCAGGGGATCAAAGTGAAATGGCGGGAGGTCGGGTGGGACGCGCTGATCGGGGAGTTCGTGCCCGGCAAGATCG
GGGCAGAGATGCTGGAGGTGGAGGCATGA

Upstream 100 bases:

>100_bases
AGGGCAAGCCCTTCAAGAGCCTGACCGCCCTGGCGCGGCACATTACCGGCACACACTGGTCTGGCCCGCTGTTCTTTGGC
CTGACCAAGGGAGGCGCACG

Downstream 100 bases:

>100_bases
CCGGCGGCGCACTGGAGACGTTCGTGCCGGTGGCGTTCCGCCGCCGGGGCGCGCGGCGGGTCGTTGCTGATGACCGGACG
ACCCACGACACGACCTTGCT

Product: site-specific integrase

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTGAVQIASAKPRKRCAVYCRVSTDERLDQEFNSIDAQKEAGHAFIVSQRSEGWISVADDYDDPGFSGGNTDRPGLRRLL
ADIERGRIDIVVVYKIDRLTRSLADFSKMVEVFERHDVSFVSVTQQFNTTTSMGRLMLNVLLSFAQFEREVTGERIRDKI
AAAKRKGLWMGGVPPLGYDVRDRQLVVNEVEATVVRRIFEEMLTIGSPTQIAARLTAEGITTKAWITQDGRARYGADIDK
KYLSKLLRNRIYLGELSHKGSWYPGTHPAIIGAELWQRVHAVLAKDSYARSTHTKGLSRTDALLRGLLYTPSGERMYPTY
SRKNGRQYRYYVSKSESRFGAPGKRYERLPAPEIEGAVVAQIRTVLTSPEAVAAVVQHIQRNGAQVDEASTVIAMGRLDD
VWERLFPTERHRIANLMIERVDLVNDGERQGIKVKWREVGWDALIGEFVPGKIGAEMLEVEA

Sequences:

>Translated_462_residues
MTGAVQIASAKPRKRCAVYCRVSTDERLDQEFNSIDAQKEAGHAFIVSQRSEGWISVADDYDDPGFSGGNTDRPGLRRLL
ADIERGRIDIVVVYKIDRLTRSLADFSKMVEVFERHDVSFVSVTQQFNTTTSMGRLMLNVLLSFAQFEREVTGERIRDKI
AAAKRKGLWMGGVPPLGYDVRDRQLVVNEVEATVVRRIFEEMLTIGSPTQIAARLTAEGITTKAWITQDGRARYGADIDK
KYLSKLLRNRIYLGELSHKGSWYPGTHPAIIGAELWQRVHAVLAKDSYARSTHTKGLSRTDALLRGLLYTPSGERMYPTY
SRKNGRQYRYYVSKSESRFGAPGKRYERLPAPEIEGAVVAQIRTVLTSPEAVAAVVQHIQRNGAQVDEASTVIAMGRLDD
VWERLFPTERHRIANLMIERVDLVNDGERQGIKVKWREVGWDALIGEFVPGKIGAEMLEVEA
>Mature_461_residues
TGAVQIASAKPRKRCAVYCRVSTDERLDQEFNSIDAQKEAGHAFIVSQRSEGWISVADDYDDPGFSGGNTDRPGLRRLLA
DIERGRIDIVVVYKIDRLTRSLADFSKMVEVFERHDVSFVSVTQQFNTTTSMGRLMLNVLLSFAQFEREVTGERIRDKIA
AAKRKGLWMGGVPPLGYDVRDRQLVVNEVEATVVRRIFEEMLTIGSPTQIAARLTAEGITTKAWITQDGRARYGADIDKK
YLSKLLRNRIYLGELSHKGSWYPGTHPAIIGAELWQRVHAVLAKDSYARSTHTKGLSRTDALLRGLLYTPSGERMYPTYS
RKNGRQYRYYVSKSESRFGAPGKRYERLPAPEIEGAVVAQIRTVLTSPEAVAAVVQHIQRNGAQVDEASTVIAMGRLDDV
WERLFPTERHRIANLMIERVDLVNDGERQGIKVKWREVGWDALIGEFVPGKIGAEMLEVEA

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787404, Length=159, Percent_Identity=32.0754716981132, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 52021; Mature: 51890

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAVQIASAKPRKRCAVYCRVSTDERLDQEFNSIDAQKEAGHAFIVSQRSEGWISVADD
CCCCEEECCCCCCCCEEEEEEECCHHHHHHHHHHCCCHHHCCCEEEEEECCCCCEEECCC
YDDPGFSGGNTDRPGLRRLLADIERGRIDIVVVYKIDRLTRSLADFSKMVEVFERHDVSF
CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
VSVTQQFNTTTSMGRLMLNVLLSFAQFEREVTGERIRDKIAAAKRKGLWMGGVPPLGYDV
EEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCC
RDRQLVVNEVEATVVRRIFEEMLTIGSPTQIAARLTAEGITTKAWITQDGRARYGADIDK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCH
KYLSKLLRNRIYLGELSHKGSWYPGTHPAIIGAELWQRVHAVLAKDSYARSTHTKGLSRT
HHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
DALLRGLLYTPSGERMYPTYSRKNGRQYRYYVSKSESRFGAPGKRYERLPAPEIEGAVVA
HHHHHHHHCCCCCCEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCHHHH
QIRTVLTSPEAVAAVVQHIQRNGAQVDEASTVIAMGRLDDVWERLFPTERHRIANLMIER
HHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHEEEECCHHHHHHHHCCHHHHHHHHHHHHH
VDLVNDGERQGIKVKWREVGWDALIGEFVPGKIGAEMLEVEA
HHHCCCCCCCCCEEEEECCCHHHHHHHCCCCHHCHHHHHCCC
>Mature Secondary Structure 
TGAVQIASAKPRKRCAVYCRVSTDERLDQEFNSIDAQKEAGHAFIVSQRSEGWISVADD
CCCEEECCCCCCCCEEEEEEECCHHHHHHHHHHCCCHHHCCCEEEEEECCCCCEEECCC
YDDPGFSGGNTDRPGLRRLLADIERGRIDIVVVYKIDRLTRSLADFSKMVEVFERHDVSF
CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
VSVTQQFNTTTSMGRLMLNVLLSFAQFEREVTGERIRDKIAAAKRKGLWMGGVPPLGYDV
EEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCC
RDRQLVVNEVEATVVRRIFEEMLTIGSPTQIAARLTAEGITTKAWITQDGRARYGADIDK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCH
KYLSKLLRNRIYLGELSHKGSWYPGTHPAIIGAELWQRVHAVLAKDSYARSTHTKGLSRT
HHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
DALLRGLLYTPSGERMYPTYSRKNGRQYRYYVSKSESRFGAPGKRYERLPAPEIEGAVVA
HHHHHHHHCCCCCCEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCHHHH
QIRTVLTSPEAVAAVVQHIQRNGAQVDEASTVIAMGRLDDVWERLFPTERHRIANLMIER
HHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHEEEECCHHHHHHHHCCHHHHHHHHHHHHH
VDLVNDGERQGIKVKWREVGWDALIGEFVPGKIGAEMLEVEA
HHHCCCCCCCCCEEEEECCCHHHHHHHCCCCHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]