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The map label for this gene is shlB [H]

Identifier: 17547901

GI number: 17547901

Start: 3440524

End: 3442275

Strand: Reverse

Name: shlB [H]

Synonym: RSc3182

Alternate gene names: 17547901

Gene position: 3442275-3440524 (Counterclockwise)

Preceding gene: 17547902

Following gene: 17547900

Centisome position: 92.62

GC content: 70.09

Gene sequence:

>1752_bases
ATGGCATTGAAACCTCTCACGCTGGCGGCGGCGTTGCTGTCCGTGGCAACCGCCCACGCGCAGGTCCTGCCGCCCGCGCC
ACCGGGTCCGGTGCTCGAAGACCCGGCCCAGCGCGCCCAGCGCGAGCGCCAGGACACCGAGCGCCGCCGCGAGGCCACGC
AGCCCGCGCCGCAGATTGCCGTCGCGCCGTCGGTGCCCGATGACGCCGCCGTCGATGCGGTGGCCGAGCCGGGCACGACC
TTCGACATCCACCGCATCGAGCTGACCGGCAACACGGTGCTGGATGCGGAAACGGTCGAGCGCGTCACGCAGCCGTTCGT
GAACCGCGCGCTCGGCACCAACCGCATCAACCTGCTGCTGCGCCGGCTGACCGAAGCGTTCGTCGCGCGCGGCTTTGTCA
CCACGCGCGCTTACCTGGCGCCGCAGAACCTCAAGGTGGGCGTGCTGACCATCGCCGTGGTGCCGGGCAAGGTCGAGGCG
CTGCAGATCAACGGCAAGACGGTCCGTACCACGGTGCCCGATGCCAAACTGGCCGAAGGACCGCAGGCCGGCGGCTGGCT
GACCGATGCCGGCACCGTGTGGTCGATGCCGGCGGTGGGCGACACGCTCAGGCTGTCCGATCTGGAGCAGGGCGTCGACC
AGATCAACCGCCTGCGCCGCAACCAGGCCGAGGTGCAGATCCTGCCGGGCCAGGCGCCGGGCGGCTCCGTGATCGCGCTG
GCCAACCAGCCGGGCGACCGCTTCCGCTTCAGCGCTGGCACCGACAACTACGGCAGCCGCGCCACCGGCACCACGCGGCT
GCGCGCCGGCATCGACGCGGACAACGCGCTCGGCTTGCAGGAGGCCGTGTCGCTGTCGTACATCGGCACGCGCGACACCA
ACGCGGCCATCGTCTCGGCGGCCGTGCCGTTCGGCTACAACACCTTCAGCTATACCGGCTCGCTGTCGGAGTACAACAGC
CTGATCGGCGATACGGCGCTGCTCTATGGGCGCACGTTCGCGCATGCCTTCGGCTGGAACCGCGTGATCGAGCGCGACCC
GGGCGGCCGCACCGCGTTCGACGTCACGCTCACGCACCGGCGCAGCGAGCGCGAGGTCAACAACCTGCTGTTCGAGCCGC
AGAGCCTGTCGGTGCTGCGCGTGGCCGTCAACGGTCTGCGCAAGTTCGCCGTCGGCAACCAGGGCGGCTATGCGACCTGG
GAGGCGGGCCTGTCGCGCGGCATGGACGCGCTCAATGCGAGCCACGATGCGCCGGACATCACGCGCGACGAGGCGCATAG
CCAGTTCTGGAAGCTGGACGGCAACGCCAGCACCCAACTGCCGCTTCCCGCCATCGGCCGCGCCGCGCTGGCCTACCGTG
GGCAGGTGTTGGCGCAGTGGTCGAACGTCGCGCTGTTCGGCTCGGAGCAGATCTTTGCCGGCGGCATGGGCTCGGTGCGC
GGCTTCCGCGAGGGGCTGATCAGCGGCGATCGCGGCCTGACGCTGCGCAACGAAGTGGTGTGGGGCAACGTGCCCGTGCT
GGCCGGCGTGCGCATCGAGCCCTATGTCTTCCTGGACGGCGGACAGACGCAGCTGGTGGCGAACCAGCACTGGCAGTACC
TGGCCGGCACCGGCATGGGCGTGCGGCTGGCCGCGAATGCCGGCAAGCATGCCTTCACCAGCGAGCTGCTGCTTGGGCGC
GCGCTGGTGCAACCCGCGGAACTTGGCAGCAAGGCAACGGTCTTGCTGGCCACAATGAACTACTCGTTTTAG

Upstream 100 bases:

>100_bases
GCAATGGCATCGTGACGGTGCGAGCCAAGTCGCGGCAGCCGGTGTCGATCGAGTCGCGAGTCGGCTTGACGTCGTGGTTG
TGGCAGTGAGGGGAAGCGCG

Downstream 100 bases:

>100_bases
CGAGCAACCAAAATGAATCGTCCTACCCAATTCTTGAAGATCACCATCGCTGTTCTGTCGGCTGTAGCCGCCATGGCGGC
GTCATCAGCCTACGCGGATG

Product: activation/secretion signal peptide protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MALKPLTLAAALLSVATAHAQVLPPAPPGPVLEDPAQRAQRERQDTERRREATQPAPQIAVAPSVPDDAAVDAVAEPGTT
FDIHRIELTGNTVLDAETVERVTQPFVNRALGTNRINLLLRRLTEAFVARGFVTTRAYLAPQNLKVGVLTIAVVPGKVEA
LQINGKTVRTTVPDAKLAEGPQAGGWLTDAGTVWSMPAVGDTLRLSDLEQGVDQINRLRRNQAEVQILPGQAPGGSVIAL
ANQPGDRFRFSAGTDNYGSRATGTTRLRAGIDADNALGLQEAVSLSYIGTRDTNAAIVSAAVPFGYNTFSYTGSLSEYNS
LIGDTALLYGRTFAHAFGWNRVIERDPGGRTAFDVTLTHRRSEREVNNLLFEPQSLSVLRVAVNGLRKFAVGNQGGYATW
EAGLSRGMDALNASHDAPDITRDEAHSQFWKLDGNASTQLPLPAIGRAALAYRGQVLAQWSNVALFGSEQIFAGGMGSVR
GFREGLISGDRGLTLRNEVVWGNVPVLAGVRIEPYVFLDGGQTQLVANQHWQYLAGTGMGVRLAANAGKHAFTSELLLGR
ALVQPAELGSKATVLLATMNYSF

Sequences:

>Translated_583_residues
MALKPLTLAAALLSVATAHAQVLPPAPPGPVLEDPAQRAQRERQDTERRREATQPAPQIAVAPSVPDDAAVDAVAEPGTT
FDIHRIELTGNTVLDAETVERVTQPFVNRALGTNRINLLLRRLTEAFVARGFVTTRAYLAPQNLKVGVLTIAVVPGKVEA
LQINGKTVRTTVPDAKLAEGPQAGGWLTDAGTVWSMPAVGDTLRLSDLEQGVDQINRLRRNQAEVQILPGQAPGGSVIAL
ANQPGDRFRFSAGTDNYGSRATGTTRLRAGIDADNALGLQEAVSLSYIGTRDTNAAIVSAAVPFGYNTFSYTGSLSEYNS
LIGDTALLYGRTFAHAFGWNRVIERDPGGRTAFDVTLTHRRSEREVNNLLFEPQSLSVLRVAVNGLRKFAVGNQGGYATW
EAGLSRGMDALNASHDAPDITRDEAHSQFWKLDGNASTQLPLPAIGRAALAYRGQVLAQWSNVALFGSEQIFAGGMGSVR
GFREGLISGDRGLTLRNEVVWGNVPVLAGVRIEPYVFLDGGQTQLVANQHWQYLAGTGMGVRLAANAGKHAFTSELLLGR
ALVQPAELGSKATVLLATMNYSF
>Mature_582_residues
ALKPLTLAAALLSVATAHAQVLPPAPPGPVLEDPAQRAQRERQDTERRREATQPAPQIAVAPSVPDDAAVDAVAEPGTTF
DIHRIELTGNTVLDAETVERVTQPFVNRALGTNRINLLLRRLTEAFVARGFVTTRAYLAPQNLKVGVLTIAVVPGKVEAL
QINGKTVRTTVPDAKLAEGPQAGGWLTDAGTVWSMPAVGDTLRLSDLEQGVDQINRLRRNQAEVQILPGQAPGGSVIALA
NQPGDRFRFSAGTDNYGSRATGTTRLRAGIDADNALGLQEAVSLSYIGTRDTNAAIVSAAVPFGYNTFSYTGSLSEYNSL
IGDTALLYGRTFAHAFGWNRVIERDPGGRTAFDVTLTHRRSEREVNNLLFEPQSLSVLRVAVNGLRKFAVGNQGGYATWE
AGLSRGMDALNASHDAPDITRDEAHSQFWKLDGNASTQLPLPAIGRAALAYRGQVLAQWSNVALFGSEQIFAGGMGSVRG
FREGLISGDRGLTLRNEVVWGNVPVLAGVRIEPYVFLDGGQTQLVANQHWQYLAGTGMGVRLAANAGKHAFTSELLLGRA
LVQPAELGSKATVLLATMNYSF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 62314; Mature: 62183

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKPLTLAAALLSVATAHAQVLPPAPPGPVLEDPAQRAQRERQDTERRREATQPAPQIA
CCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
VAPSVPDDAAVDAVAEPGTTFDIHRIELTGNTVLDAETVERVTQPFVNRALGTNRINLLL
ECCCCCCCHHHHHHCCCCCEEEEEEEEECCCEEECHHHHHHHHHHHHHHHCCCHHHHHHH
RRLTEAFVARGFVTTRAYLAPQNLKVGVLTIAVVPGKVEALQINGKTVRTTVPDAKLAEG
HHHHHHHHHHCHHHHEEEECCCCCEEEEEEEEEECCCEEEEEECCEEEEEECCCCHHCCC
PQAGGWLTDAGTVWSMPAVGDTLRLSDLEQGVDQINRLRRNQAEVQILPGQAPGGSVIAL
CCCCCEEECCCCEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEE
ANQPGDRFRFSAGTDNYGSRATGTTRLRAGIDADNALGLQEAVSLSYIGTRDTNAAIVSA
ECCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHEEEEECCCCCCCEEEEE
AVPFGYNTFSYTGSLSEYNSLIGDTALLYGRTFAHAFGWNRVIERDPGGRTAFDVTLTHR
ECCCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHHHHCCCHHEECCCCCCEEEEEEEECC
RSEREVNNLLFEPQSLSVLRVAVNGLRKFAVGNQGGYATWEAGLSRGMDALNASHDAPDI
CHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCHHHHCCCCCCCCC
TRDEAHSQFWKLDGNASTQLPLPAIGRAALAYRGQVLAQWSNVALFGSEQIFAGGMGSVR
CHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEECCEEEECCCEEEECCCCHHH
GFREGLISGDRGLTLRNEVVWGNVPVLAGVRIEPYVFLDGGQTQLVANQHWQYLAGTGMG
HHHHHHCCCCCCCEEECEEEECCCCEEECEEECCEEEECCCCEEEEECCCEEEEECCCCC
VRLAANAGKHAFTSELLLGRALVQPAELGSKATVLLATMNYSF
EEEECCCCCHHHHHHHHHHHHHCCHHHCCCCEEEEEEEECCCC
>Mature Secondary Structure 
ALKPLTLAAALLSVATAHAQVLPPAPPGPVLEDPAQRAQRERQDTERRREATQPAPQIA
CCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
VAPSVPDDAAVDAVAEPGTTFDIHRIELTGNTVLDAETVERVTQPFVNRALGTNRINLLL
ECCCCCCCHHHHHHCCCCCEEEEEEEEECCCEEECHHHHHHHHHHHHHHHCCCHHHHHHH
RRLTEAFVARGFVTTRAYLAPQNLKVGVLTIAVVPGKVEALQINGKTVRTTVPDAKLAEG
HHHHHHHHHHCHHHHEEEECCCCCEEEEEEEEEECCCEEEEEECCEEEEEECCCCHHCCC
PQAGGWLTDAGTVWSMPAVGDTLRLSDLEQGVDQINRLRRNQAEVQILPGQAPGGSVIAL
CCCCCEEECCCCEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEE
ANQPGDRFRFSAGTDNYGSRATGTTRLRAGIDADNALGLQEAVSLSYIGTRDTNAAIVSA
ECCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHEEEEECCCCCCCEEEEE
AVPFGYNTFSYTGSLSEYNSLIGDTALLYGRTFAHAFGWNRVIERDPGGRTAFDVTLTHR
ECCCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHHHHCCCHHEECCCCCCEEEEEEEECC
RSEREVNNLLFEPQSLSVLRVAVNGLRKFAVGNQGGYATWEAGLSRGMDALNASHDAPDI
CHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCHHHHCCCCCCCCC
TRDEAHSQFWKLDGNASTQLPLPAIGRAALAYRGQVLAQWSNVALFGSEQIFAGGMGSVR
CHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEECCEEEECCCEEEECCCCHHH
GFREGLISGDRGLTLRNEVVWGNVPVLAGVRIEPYVFLDGGQTQLVANQHWQYLAGTGMG
HHHHHHCCCCCCCEEECEEEECCCCEEECEEECCEEEECCCCEEEEECCCEEEEECCCCC
VRLAANAGKHAFTSELLLGRALVQPAELGSKATVLLATMNYSF
EEEECCCCCHHHHHHHHHHHHHCCHHHCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]