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The map label for this gene is 17547882

Identifier: 17547882

GI number: 17547882

Start: 3421520

End: 3423622

Strand: Direct

Name: 17547882

Synonym: RSc3163

Alternate gene names: NA

Gene position: 3421520-3423622 (Clockwise)

Preceding gene: 17547881

Following gene: 17547883

Centisome position: 92.07

GC content: 70.04

Gene sequence:

>2103_bases
ATGTCACTCCCGCCCAGTCGCCCGGAAACCCTGAGCATCCCGGAAGCGCTCCACCGCGCCCACGCTCACTGGAGCGCCGG
TCAGGCCGCCCAGGCGGAGCTGCTGTGCCAGCGCGTGCTGGCCGCCTGGCCCGGTCAGGCCGATGCGCTGCACCTGCTTG
GCCTGATGGCGCATGCCTACGGCCATCTCGATCTCGCCATCGCTCACCTGCGCCAGGCTTGCCTGGCACCGCGCGCCCCA
GCGGCCTATTCCAGCAATCTGGCCGAGATGTACCGCCAGAAGGGGTTGCTCGCCGAAGCGGAAGACGCGGCCCGCCGCGC
GGTGGCCATGGACCCGGCGCTGGTGTCGGGCTGGAACAATCTGGGCATCGTGCTGCAAGAGGCGGGCAAGTTTGCGGAAA
GCCTCGACTGCCTGGAGCGCGTGATCTTGCTCCAGCCCGACGGGGCGCAGGCGCACAACAATCTCGCCAACACGTTGAGG
CGCCTGGAGCGTCTGGAGCGTGCGGAGTCTCACTACCGCCAGGCGCTGGAACTGGATCCGGCCTATGCCGAGGCACACAG
CAACCTGGCATTCCTGCTGTCCGCCCAGGGCCGCCACGACGAAGCGGCCGCCGCTGCCCAGCACGCCATCGAACTCAGCC
CGCGCCTGGTGGACGCCTATCTGAACCTGGCGGAGGCGGAAATGGGCCGCCACCGCCATGAGGCCGCCCTACGGGTGCTG
GATACGCTCTCGACCTTCGCCCCGCAGCATCCGGCCGCACTGACGGCGCGCGCGAACGTGCTCAAGCGTGTCGAACGCCT
CGATGAGGCGCTCGCCGTTGCACGCCAGGCGGTGGTGCTGGCCCCCCGCAGCGCCGAGGCGCACCACGCGCTCGCGATGG
CGCTCCAGACGCTCGGGCAAACCGACGAGGCGCTGCCGCATTTCGAGCAGGCGGCGCGGCTGCCCGGCGCGGTGGCCGAG
GAAGCGCTGGTCGGGCGCGCCACCCTGCTGATGGAAGCGGGCCGCCGGGATGCGGCACGCGCCGCCTTCGACCAGGCGCT
GGAGCAGTTTCCGGGCTCGGTGCAGGCACTGGCCGGCCGCGCCGATGCGCGGACCTTCACGGCCGGCGACCCCGACATCG
CGGCGCTCGAAGCGTGCCTCGCCGAAGGCGAGCGTCGCTCGCTGCGCGACCGGATCTCGGCCCATTTCGCGCTCGGCAAG
GCCTACCTCGACCTCCAGGATCCGGCGCGGGCCTTTCATCACCTCGACGCGGGCAACCGGCAGAAACGTTCGACCTTCAC
CTATGACGGCGCCGCGAGCCGCCGGTGGATGGAGCGCATCGCCGAAGCCTTTCCCCCGGAACGGCATGACCCGCTGCATG
CCACCGGCGAGCCGTCAGCGTTGCCGGTGTTCATCGTCGGCATGCCGCGCTCGGGCACCACGCTGATCGAGCAGATCGTG
TCGTCGCACCCGCAGGTCATGGGCGCCGGCGAACTGTCGGCCCTGCGCCTGGTGGTCGAAGGCAGCGGCCTGTTCCCGGA
CGGCATGCAACGGTTGGCAGGCGAGGCGCGCGGCGCGCTGTTCCGGCAGCTCGGACAGGCGTATCTGTCGCGCGTCGCGC
CGCTCGCCCAGGGACGGGCGCGGCTGGTCGACAAGATGCCGAGCAATTTCCTGTACGCCAGGCTGATCCCGCTGATCCTG
CCGGGGGCGCGCATCATCCATGCCCGCCGCGACCCGGTGGATACCTGCCTGTCCTGCTACACCAAGCTCTTCGCCGGCGA
GCAGCAGTTCGCCTACGACCAGGCCGAACTGGGGGCGCTCTACCGCGGCTACGCGCGCCTGATGGCGCATTGGCGCGCAG
TGTTGCCACCCGGCTGCTTCATCGAGGTTGACTACGAGGCCGTGGTGGATGACCTGGAAGGCGAGGCGCGGCGCTTGATC
GATTTCCTGGACCTGCCATGGAACCCGGCCTGCCTGCACTTCCATGACAACCGCCGGGTGGTGCGCACCGCCAGCGTCAA
CCAGGTGCGGCAGCCAATCTACACAACCTCGAAGGGTCGCTGGCAGGCGTATGCCGACTATCTCGGCCCGCTGCTGGAGG
CACTTGGGGTCGAGGCGCCATGA

Upstream 100 bases:

>100_bases
ACAGTGCGCGTAGGCGATCCGGCGGTTTGCATGGCCCCTACCGCTGGCATGAACGTATAGCATCCCCACTTTTGTCTTTC
CCGCTGGTTCCAGCGCCGCC

Downstream 100 bases:

>100_bases
TGTCCGGCGCGCTGTCCGCGGTCCAGGCGATCGAGCACCAGGTCCGCCAGCTGCTCGCGGCCGGACGCTTCGAAGAAGCC
GAAGCGCTGGTGCGCCCGCC

Product: TPR domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MSLPPSRPETLSIPEALHRAHAHWSAGQAAQAELLCQRVLAAWPGQADALHLLGLMAHAYGHLDLAIAHLRQACLAPRAP
AAYSSNLAEMYRQKGLLAEAEDAARRAVAMDPALVSGWNNLGIVLQEAGKFAESLDCLERVILLQPDGAQAHNNLANTLR
RLERLERAESHYRQALELDPAYAEAHSNLAFLLSAQGRHDEAAAAAQHAIELSPRLVDAYLNLAEAEMGRHRHEAALRVL
DTLSTFAPQHPAALTARANVLKRVERLDEALAVARQAVVLAPRSAEAHHALAMALQTLGQTDEALPHFEQAARLPGAVAE
EALVGRATLLMEAGRRDAARAAFDQALEQFPGSVQALAGRADARTFTAGDPDIAALEACLAEGERRSLRDRISAHFALGK
AYLDLQDPARAFHHLDAGNRQKRSTFTYDGAASRRWMERIAEAFPPERHDPLHATGEPSALPVFIVGMPRSGTTLIEQIV
SSHPQVMGAGELSALRLVVEGSGLFPDGMQRLAGEARGALFRQLGQAYLSRVAPLAQGRARLVDKMPSNFLYARLIPLIL
PGARIIHARRDPVDTCLSCYTKLFAGEQQFAYDQAELGALYRGYARLMAHWRAVLPPGCFIEVDYEAVVDDLEGEARRLI
DFLDLPWNPACLHFHDNRRVVRTASVNQVRQPIYTTSKGRWQAYADYLGPLLEALGVEAP

Sequences:

>Translated_700_residues
MSLPPSRPETLSIPEALHRAHAHWSAGQAAQAELLCQRVLAAWPGQADALHLLGLMAHAYGHLDLAIAHLRQACLAPRAP
AAYSSNLAEMYRQKGLLAEAEDAARRAVAMDPALVSGWNNLGIVLQEAGKFAESLDCLERVILLQPDGAQAHNNLANTLR
RLERLERAESHYRQALELDPAYAEAHSNLAFLLSAQGRHDEAAAAAQHAIELSPRLVDAYLNLAEAEMGRHRHEAALRVL
DTLSTFAPQHPAALTARANVLKRVERLDEALAVARQAVVLAPRSAEAHHALAMALQTLGQTDEALPHFEQAARLPGAVAE
EALVGRATLLMEAGRRDAARAAFDQALEQFPGSVQALAGRADARTFTAGDPDIAALEACLAEGERRSLRDRISAHFALGK
AYLDLQDPARAFHHLDAGNRQKRSTFTYDGAASRRWMERIAEAFPPERHDPLHATGEPSALPVFIVGMPRSGTTLIEQIV
SSHPQVMGAGELSALRLVVEGSGLFPDGMQRLAGEARGALFRQLGQAYLSRVAPLAQGRARLVDKMPSNFLYARLIPLIL
PGARIIHARRDPVDTCLSCYTKLFAGEQQFAYDQAELGALYRGYARLMAHWRAVLPPGCFIEVDYEAVVDDLEGEARRLI
DFLDLPWNPACLHFHDNRRVVRTASVNQVRQPIYTTSKGRWQAYADYLGPLLEALGVEAP
>Mature_699_residues
SLPPSRPETLSIPEALHRAHAHWSAGQAAQAELLCQRVLAAWPGQADALHLLGLMAHAYGHLDLAIAHLRQACLAPRAPA
AYSSNLAEMYRQKGLLAEAEDAARRAVAMDPALVSGWNNLGIVLQEAGKFAESLDCLERVILLQPDGAQAHNNLANTLRR
LERLERAESHYRQALELDPAYAEAHSNLAFLLSAQGRHDEAAAAAQHAIELSPRLVDAYLNLAEAEMGRHRHEAALRVLD
TLSTFAPQHPAALTARANVLKRVERLDEALAVARQAVVLAPRSAEAHHALAMALQTLGQTDEALPHFEQAARLPGAVAEE
ALVGRATLLMEAGRRDAARAAFDQALEQFPGSVQALAGRADARTFTAGDPDIAALEACLAEGERRSLRDRISAHFALGKA
YLDLQDPARAFHHLDAGNRQKRSTFTYDGAASRRWMERIAEAFPPERHDPLHATGEPSALPVFIVGMPRSGTTLIEQIVS
SHPQVMGAGELSALRLVVEGSGLFPDGMQRLAGEARGALFRQLGQAYLSRVAPLAQGRARLVDKMPSNFLYARLIPLILP
GARIIHARRDPVDTCLSCYTKLFAGEQQFAYDQAELGALYRGYARLMAHWRAVLPPGCFIEVDYEAVVDDLEGEARRLID
FLDLPWNPACLHFHDNRRVVRTASVNQVRQPIYTTSKGRWQAYADYLGPLLEALGVEAP

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=291, Percent_Identity=29.8969072164948, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI32307148, Length=291, Percent_Identity=29.8969072164948, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI118766330, Length=240, Percent_Identity=30, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI118766328, Length=240, Percent_Identity=30, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI301336134, Length=247, Percent_Identity=30.7692307692308, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI83415184, Length=247, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115532692, Length=267, Percent_Identity=29.5880149812734, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI115532690, Length=310, Percent_Identity=27.741935483871, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17647755, Length=288, Percent_Identity=29.1666666666667, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585827, Length=288, Percent_Identity=29.1666666666667, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585829, Length=288, Percent_Identity=29.1666666666667, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24647123, Length=237, Percent_Identity=25.3164556962025, Blast_Score=73, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281364285, Length=160, Percent_Identity=33.125, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581187, Length=160, Percent_Identity=33.125, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19920486, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076610, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000863
- InterPro:   IPR001440
- InterPro:   IPR011717
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00685 Sulfotransfer_1; PF00515 TPR_1; PF07721 TPR_4 [H]

EC number: NA

Molecular weight: Translated: 76493; Mature: 76362

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPPSRPETLSIPEALHRAHAHWSAGQAAQAELLCQRVLAAWPGQADALHLLGLMAHAY
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GHLDLAIAHLRQACLAPRAPAAYSSNLAEMYRQKGLLAEAEDAARRAVAMDPALVSGWNN
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCCCCC
LGIVLQEAGKFAESLDCLERVILLQPDGAQAHNNLANTLRRLERLERAESHYRQALELDP
CHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AYAEAHSNLAFLLSAQGRHDEAAAAAQHAIELSPRLVDAYLNLAEAEMGRHRHEAALRVL
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTLSTFAPQHPAALTARANVLKRVERLDEALAVARQAVVLAPRSAEAHHALAMALQTLGQ
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
TDEALPHFEQAARLPGAVAEEALVGRATLLMEAGRRDAARAAFDQALEQFPGSVQALAGR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCC
ADARTFTAGDPDIAALEACLAEGERRSLRDRISAHFALGKAYLDLQDPARAFHHLDAGNR
CCCCEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
QKRSTFTYDGAASRRWMERIAEAFPPERHDPLHATGEPSALPVFIVGMPRSGTTLIEQIV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHH
SSHPQVMGAGELSALRLVVEGSGLFPDGMQRLAGEARGALFRQLGQAYLSRVAPLAQGRA
HCCCCEECCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVDKMPSNFLYARLIPLILPGARIIHARRDPVDTCLSCYTKLFAGEQQFAYDQAELGAL
HHHHHCCCHHHHHHHHHHHCCCHHHEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YRGYARLMAHWRAVLPPGCFIEVDYEAVVDDLEGEARRLIDFLDLPWNPACLHFHDNRRV
HHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEECCCCE
VRTASVNQVRQPIYTTSKGRWQAYADYLGPLLEALGVEAP
EEECCHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLPPSRPETLSIPEALHRAHAHWSAGQAAQAELLCQRVLAAWPGQADALHLLGLMAHAY
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GHLDLAIAHLRQACLAPRAPAAYSSNLAEMYRQKGLLAEAEDAARRAVAMDPALVSGWNN
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCCCCC
LGIVLQEAGKFAESLDCLERVILLQPDGAQAHNNLANTLRRLERLERAESHYRQALELDP
CHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AYAEAHSNLAFLLSAQGRHDEAAAAAQHAIELSPRLVDAYLNLAEAEMGRHRHEAALRVL
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTLSTFAPQHPAALTARANVLKRVERLDEALAVARQAVVLAPRSAEAHHALAMALQTLGQ
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
TDEALPHFEQAARLPGAVAEEALVGRATLLMEAGRRDAARAAFDQALEQFPGSVQALAGR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCC
ADARTFTAGDPDIAALEACLAEGERRSLRDRISAHFALGKAYLDLQDPARAFHHLDAGNR
CCCCEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
QKRSTFTYDGAASRRWMERIAEAFPPERHDPLHATGEPSALPVFIVGMPRSGTTLIEQIV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHH
SSHPQVMGAGELSALRLVVEGSGLFPDGMQRLAGEARGALFRQLGQAYLSRVAPLAQGRA
HCCCCEECCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVDKMPSNFLYARLIPLILPGARIIHARRDPVDTCLSCYTKLFAGEQQFAYDQAELGAL
HHHHHCCCHHHHHHHHHHHCCCHHHEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YRGYARLMAHWRAVLPPGCFIEVDYEAVVDDLEGEARRLIDFLDLPWNPACLHFHDNRRV
HHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEECCCCE
VRTASVNQVRQPIYTTSKGRWQAYADYLGPLLEALGVEAP
EEECCHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]