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The map label for this gene is glpD [H]

Identifier: 17547764

GI number: 17547764

Start: 3281615

End: 3283192

Strand: Direct

Name: glpD [H]

Synonym: RSc3045

Alternate gene names: 17547764

Gene position: 3281615-3283192 (Clockwise)

Preceding gene: 17547708

Following gene: 17547765

Centisome position: 88.3

GC content: 69.71

Gene sequence:

>1578_bases
ATGCACCATACCGATGCGTCGCATCTGGACTGTGATCTGCTGGTGGTCGGAGGAGGCATCAACGGGGTCGGCATCGCGCG
CGACGCCGTGGGCCGTGGCCTGTCGGTGGTCTTGTGCGAGAAGGACGACCTGGCCCAGCACACCTCTTCGGCATCGACCA
AGCTGATCCACGGCGGGCTGCGTTATCTCGAATATTACGAATTCAGCCTCGTGCGCAAGGCGCTGCTGGAGCGCGAGGTG
CTGCTGCGCATGGCGCCGCACATCATGTGGCCGCTGCGCTTCGTGATGCCGCATGACCGCAGCCAGCGGCCGGCCTGGAT
GATCCGCGCGGGTCTCTTCCTATATGACCACCTGGCGCGCCGGCGCTTTCTGCCCGGCTCGGAGGCGGTCAGGCTGGCGC
AGCATCCGGCGGGCGGGCCGCTCAAGCCCGGCTTTGCGCGCGGCTTCGTCTATTCCGACGGGTGGGTGGACGACGCCCGC
CTGGTGGTGCTCAATGCCAGCGATGCCGCCGACCGCGGTGCGCAGATCCTCACCCGCACCCGCTGCCTGAACGCGGAGCG
CCGCGCCGACGGCTGGCATGCGTCGCTGGCGGGGCCGGACGGCATCCGCTCCGTGCGGGCGAAGGCGATCGTCAACGCGG
CCGGACCGTGGGCCGCAGAGTTCGCCCGGGCGGCCCACGCGCTGCCGGACACGCGCGGCCTGCGCCTCATCAAGGGCAGC
CACATCATCGTGCGGCGGATGTTCGACCATCCGTTCGCCTATATCTTCCAGAACCCGGACGGGCGGATCGTCTTTGCGAT
CCCGTACCAGGATGACTTCACGCTAATCGGCACGACGGACCTGGAGTACACCGGCCCGCTGGACCAGGTCGCCATCGACG
CCGGCGAGATCAACTACCTGTGCGAGATGGCCAACCGCTATTTCGCGCGGCAGCTGACGCCCGCCGATGTGGTGTGGAAT
TACTCGGGCGTGCGGCCGCTGCTCGACGACAGCGCCGCCAGTGCGTCGGCCATCACGCGCGACTATCTGGTCGAATGCGA
GACCGGGGCCGATGGGCGCGCGGCGCCGCTGATCAATGTCTGGGGCGGCAAGATCACCACCTACCGCAAGCTGGCCGAGG
AAGCGCTGGACAAGCTGGCGCCGCACCTGCCGGCGGCGGGCGCACCGTCGTGGACGGCCACGGCCGCCCTGCCCGGCGGC
GATCTGGAGGCGCCCGGCCAGTTGGTCGGGCAGTACACCTTCGCCGATTTTGTGACCCGCCTGCAAAAACGTTTGCCATG
GCTGCCCGCCAGGCTGGCGAAGCGCTATGCGCACCAGTACGGCACGCGCGTGACCACGCTGCTCGCGGGCGCGGCGCGGC
TGGACGACCTGGGCGCGGAGGTCACGCCAGGCCTGTACGAAGCCGAGATCCGCTACCTGATCGAGTACGAATGGGCCCGC
ACGGCGCAGGACATCCTGTGGCGGCGGACCAAGCTGGGCCTGTACGCCGCCGAGGCCGACCGCGGCCGCCTGGAAGCCTG
GCTGACGCGGCACCCGCCGACCGTCGAGGCCGATCCGGAGGCGCTGCGCGCGCCCTGA

Upstream 100 bases:

>100_bases
TTCCCTATGTTGCTTTATTTTCGCCTTTCACTACACTATCCGCCAACGCGTCACTATTCGCAACAAAAGACGCGCAAATC
AACAGAAACCCATCTGATCC

Downstream 100 bases:

>100_bases
GCCGCCACGCCCGGCAAGACACACAAGAAAAAAGAAGGGAGACGCAATTGATTCTGGAACTGGACCAGGTCACGGCCGTG
GCCGGCGCACAGACCCATCT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MHHTDASHLDCDLLVVGGGINGVGIARDAVGRGLSVVLCEKDDLAQHTSSASTKLIHGGLRYLEYYEFSLVRKALLEREV
LLRMAPHIMWPLRFVMPHDRSQRPAWMIRAGLFLYDHLARRRFLPGSEAVRLAQHPAGGPLKPGFARGFVYSDGWVDDAR
LVVLNASDAADRGAQILTRTRCLNAERRADGWHASLAGPDGIRSVRAKAIVNAAGPWAAEFARAAHALPDTRGLRLIKGS
HIIVRRMFDHPFAYIFQNPDGRIVFAIPYQDDFTLIGTTDLEYTGPLDQVAIDAGEINYLCEMANRYFARQLTPADVVWN
YSGVRPLLDDSAASASAITRDYLVECETGADGRAAPLINVWGGKITTYRKLAEEALDKLAPHLPAAGAPSWTATAALPGG
DLEAPGQLVGQYTFADFVTRLQKRLPWLPARLAKRYAHQYGTRVTTLLAGAARLDDLGAEVTPGLYEAEIRYLIEYEWAR
TAQDILWRRTKLGLYAAEADRGRLEAWLTRHPPTVEADPEALRAP

Sequences:

>Translated_525_residues
MHHTDASHLDCDLLVVGGGINGVGIARDAVGRGLSVVLCEKDDLAQHTSSASTKLIHGGLRYLEYYEFSLVRKALLEREV
LLRMAPHIMWPLRFVMPHDRSQRPAWMIRAGLFLYDHLARRRFLPGSEAVRLAQHPAGGPLKPGFARGFVYSDGWVDDAR
LVVLNASDAADRGAQILTRTRCLNAERRADGWHASLAGPDGIRSVRAKAIVNAAGPWAAEFARAAHALPDTRGLRLIKGS
HIIVRRMFDHPFAYIFQNPDGRIVFAIPYQDDFTLIGTTDLEYTGPLDQVAIDAGEINYLCEMANRYFARQLTPADVVWN
YSGVRPLLDDSAASASAITRDYLVECETGADGRAAPLINVWGGKITTYRKLAEEALDKLAPHLPAAGAPSWTATAALPGG
DLEAPGQLVGQYTFADFVTRLQKRLPWLPARLAKRYAHQYGTRVTTLLAGAARLDDLGAEVTPGLYEAEIRYLIEYEWAR
TAQDILWRRTKLGLYAAEADRGRLEAWLTRHPPTVEADPEALRAP
>Mature_525_residues
MHHTDASHLDCDLLVVGGGINGVGIARDAVGRGLSVVLCEKDDLAQHTSSASTKLIHGGLRYLEYYEFSLVRKALLEREV
LLRMAPHIMWPLRFVMPHDRSQRPAWMIRAGLFLYDHLARRRFLPGSEAVRLAQHPAGGPLKPGFARGFVYSDGWVDDAR
LVVLNASDAADRGAQILTRTRCLNAERRADGWHASLAGPDGIRSVRAKAIVNAAGPWAAEFARAAHALPDTRGLRLIKGS
HIIVRRMFDHPFAYIFQNPDGRIVFAIPYQDDFTLIGTTDLEYTGPLDQVAIDAGEINYLCEMANRYFARQLTPADVVWN
YSGVRPLLDDSAASASAITRDYLVECETGADGRAAPLINVWGGKITTYRKLAEEALDKLAPHLPAAGAPSWTATAALPGG
DLEAPGQLVGQYTFADFVTRLQKRLPWLPARLAKRYAHQYGTRVTTLLAGAARLDDLGAEVTPGLYEAEIRYLIEYEWAR
TAQDILWRRTKLGLYAAEADRGRLEAWLTRHPPTVEADPEALRAP

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=526, Percent_Identity=30.6083650190114, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI285002231, Length=526, Percent_Identity=30.6083650190114, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI2367226, Length=480, Percent_Identity=49.5833333333333, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1788574, Length=490, Percent_Identity=27.5510204081633, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI115534726, Length=521, Percent_Identity=29.3666026871401, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17509253, Length=534, Percent_Identity=28.8389513108614, Blast_Score=141, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6322036, Length=545, Percent_Identity=27.1559633027523, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI161077125, Length=521, Percent_Identity=29.7504798464491, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24653942, Length=521, Percent_Identity=29.7504798464491, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24653944, Length=521, Percent_Identity=29.7504798464491, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI20130025, Length=521, Percent_Identity=29.7504798464491, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24586295, Length=394, Percent_Identity=27.1573604060914, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19921278, Length=525, Percent_Identity=24.952380952381, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57983; Mature: 57983

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHTDASHLDCDLLVVGGGINGVGIARDAVGRGLSVVLCEKDDLAQHTSSASTKLIHGGL
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCEEEEECCHHHHHHHCCCHHHHHHHHH
RYLEYYEFSLVRKALLEREVLLRMAPHIMWPLRFVMPHDRSQRPAWMIRAGLFLYDHLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RRFLPGSEAVRLAQHPAGGPLKPGFARGFVYSDGWVDDARLVVLNASDAADRGAQILTRT
HCCCCCHHHHHHHCCCCCCCCCCCHHCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHH
RCLNAERRADGWHASLAGPDGIRSVRAKAIVNAAGPWAAEFARAAHALPDTRGLRLIKGS
HHCCCHHCCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECC
HIIVRRMFDHPFAYIFQNPDGRIVFAIPYQDDFTLIGTTDLEYTGPLDQVAIDAGEINYL
CEEEHHHHCCCEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHEECCCHHHHH
CEMANRYFARQLTPADVVWNYSGVRPLLDDSAASASAITRDYLVECETGADGRAAPLINV
HHHHHHHHHHCCCCHHEEECCCCCCHHHCCCCHHHHHHHHHHEEEECCCCCCCCCCEEEE
WGGKITTYRKLAEEALDKLAPHLPAAGAPSWTATAALPGGDLEAPGQLVGQYTFADFVTR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
LQKRLPWLPARLAKRYAHQYGTRVTTLLAGAARLDDLGAEVTPGLYEAEIRYLIEYEWAR
HHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEEEEHHHH
TAQDILWRRTKLGLYAAEADRGRLEAWLTRHPPTVEADPEALRAP
HHHHHHHHHHHCCEEEECCCCCHHHHHHHCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MHHTDASHLDCDLLVVGGGINGVGIARDAVGRGLSVVLCEKDDLAQHTSSASTKLIHGGL
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCEEEEECCHHHHHHHCCCHHHHHHHHH
RYLEYYEFSLVRKALLEREVLLRMAPHIMWPLRFVMPHDRSQRPAWMIRAGLFLYDHLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RRFLPGSEAVRLAQHPAGGPLKPGFARGFVYSDGWVDDARLVVLNASDAADRGAQILTRT
HCCCCCHHHHHHHCCCCCCCCCCCHHCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHH
RCLNAERRADGWHASLAGPDGIRSVRAKAIVNAAGPWAAEFARAAHALPDTRGLRLIKGS
HHCCCHHCCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECC
HIIVRRMFDHPFAYIFQNPDGRIVFAIPYQDDFTLIGTTDLEYTGPLDQVAIDAGEINYL
CEEEHHHHCCCEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHEECCCHHHHH
CEMANRYFARQLTPADVVWNYSGVRPLLDDSAASASAITRDYLVECETGADGRAAPLINV
HHHHHHHHHHCCCCHHEEECCCCCCHHHCCCCHHHHHHHHHHEEEECCCCCCCCCCEEEE
WGGKITTYRKLAEEALDKLAPHLPAAGAPSWTATAALPGGDLEAPGQLVGQYTFADFVTR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
LQKRLPWLPARLAKRYAHQYGTRVTTLLAGAARLDDLGAEVTPGLYEAEIRYLIEYEWAR
HHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEEEEHHHH
TAQDILWRRTKLGLYAAEADRGRLEAWLTRHPPTVEADPEALRAP
HHHHHHHHHHHCCEEEECCCCCHHHHHHHCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]