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The map label for this gene is recQ [H]

Identifier: 17547744

GI number: 17547744

Start: 3245533

End: 3247446

Strand: Reverse

Name: recQ [H]

Synonym: RSc3025

Alternate gene names: 17547744

Gene position: 3247446-3245533 (Counterclockwise)

Preceding gene: 17547745

Following gene: 17547743

Centisome position: 87.38

GC content: 70.9

Gene sequence:

>1914_bases
ATGTTCGATTCTCCCGCCATTGACCACGCGCTCGACGCGTTGCCCGAAGATACGGCCGCCGCCACGCGCGCCGTGCTGCA
CGACGTGTTCGGCTACAGCGCGTTCCGCGGGCCGCAGGCGGACATCGTTGCCCACGTCGCCGACGGCGGCGATTGCCTGG
TGCTGATGCCCACCGGCGGCGGCAAGTCGCTCTGTTATCAGATTCCCGCCCTGGTGCGGCACCGGCGCGGCCAGGGCGCG
GGCATCGTGGTCTCGCCGCTGATCGCCCTGATGCAGGACCAGGTGGCCGCGCTGGAAGAGGCCGGTGTGCGCGCCGCCTA
CCTCAATTCCGCGCTCAGCGGCGCCGAGGCCGCGCAGGTCGAGCGCGATCTGGCGGCCGGCCGGCTCGATCTCGTCTACG
TCGCGCCCGAACGGCTGATGACGCCGCGCTTCCTCGAACTGCTGGAGCGCTCGCGCATCGGCCTGTTCGCCATCGATGAG
GCGCATTGCGTGTCGCAGTGGGGGCACGATTTCCGGCCGGAGTACATCCAGCTCTCCGTGCTGCACGAGCGCTTCCCGCA
CGTGCCGCGCATCGCGCTGACCGCCACCGCCGACGCCGTCACGCGCGACGAGATCGTCGAGCGGCTGGCGCTGGGCGGCG
CCCGCGTCTTCCTCTCCAGCTTCGACCGCCCCAACATCCGCTACACCATCGTCGAGAAGGACAGCGCGCGCCAGCAGCTG
CTGCGCTTCATCCGCGCCGAGCACCTCGGCGAAGACGGCTGCGACGCCGGCATCATCTATTGTCTGTCGCGCAAGAAGGT
GGAAGAGACCGCGCAGTGGCTGGCCGAGCAGGGCCTCCGCGCGCTGCCCTACCACGCCGGCATGGACGCCGAGACGCGCG
CCCGCCACCAGGCCATCTTCCGTAAGGAGGAGGGCGTGGTGATGGTGGCGACCATCGCCTTCGGCATGGGCATCGACAAG
CCGGACGTGCGCTTCGTCGCCCATCTGGACTTGCCCAAGAGCCTGGAGGGCTACTACCAGGAAACCGGCCGCGCCGGCCG
CGACGGCCTGCCCGCCAACGCGTGGATGGCCTACGGCCTGGCCGATGTGGTGCAGCAGCGCCGCATGATCGACGAGTCCG
ACGCCGACGACGTGCACAAGCGTGTCTCGACGGCCAAGCTCGATGCGCTGCTGGGGCTGTGCGAGTCGGCGGGATGCCGC
CGCGTGGCCCTGCTGGCGTATTTCGGCGAGTCCAGCGAGCCTTGCGGCAACTGCGACACCTGCCTGAGCCCGCCGCAGAC
CTGGGACGCGACCCGCGAGGCGCAGATGGCGCTGTCGTGCGTGTACCGCGTGCAGCAGGCCAGCCGCGTGAGCTTCGGCG
CCGGCCAACTGATCGACATCCTGCGCGGCAACGCCACCGAGCGCATCAAGCAATGGCATCACGAGACGCTGTCCACTTTC
GGCATCGGCAACGCCCTGTCGGAGCGCGCGTGGCGCGGCGTGTTCCGCCAGCTGGTGGCGCAGGGGCTGCTGGCGGTCGA
TCACGGCGGCCATGGCGCCCTGGTGCTGACCGACGCCGCGCGCCCGGTGCTCAAGGGCGCGCAGCATGTGACCTTGCGGC
GCCAGGCGGAGAAGGTGCGTGCCGCGCCCGCGTCCGGCGCCAAGTCCGAGCGTCGCGCGGATCCCGCCGCGGAGCTATCG
GCCGAGGCCCAGGTGCGCTGGCAGGCACTGCGCGTCTGGCGGGCCCAGACCGCGCGCGAGCACAGCGTGCCCGCCTATGT
GATCTTCCATGACGCCACGCTCGCCCGCATCGCCGAATCCGATCCCGCTTCGCGCGACGCGCTCGCCGAGCTGCCCGGCA
TCGGTGTCGCCAAGCTGGACCGTTACGGCCAGGCCTTGCTCGACGTGCTGGCCAAGTGCCGGGGCGAGGTCTAG

Upstream 100 bases:

>100_bases
CAAGGATTGAGACGCGTCCGATTGCCCGACCCGCGGCGGGGTTTGTCACAATAGCGGTTTCGACCCATCCGCAGTGACAC
CGCGCGCACCCGCCGTCCCG

Downstream 100 bases:

>100_bases
CGGCAACCGTCCGCGATCGGGGCGCGAACCGGCGGGCGCATCCCCATCGTGGGATTGCGTCGATTGCTGCACGTTTCGCC
TTCCAGTCGCAGTGTCCGCC

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MFDSPAIDHALDALPEDTAAATRAVLHDVFGYSAFRGPQADIVAHVADGGDCLVLMPTGGGKSLCYQIPALVRHRRGQGA
GIVVSPLIALMQDQVAALEEAGVRAAYLNSALSGAEAAQVERDLAAGRLDLVYVAPERLMTPRFLELLERSRIGLFAIDE
AHCVSQWGHDFRPEYIQLSVLHERFPHVPRIALTATADAVTRDEIVERLALGGARVFLSSFDRPNIRYTIVEKDSARQQL
LRFIRAEHLGEDGCDAGIIYCLSRKKVEETAQWLAEQGLRALPYHAGMDAETRARHQAIFRKEEGVVMVATIAFGMGIDK
PDVRFVAHLDLPKSLEGYYQETGRAGRDGLPANAWMAYGLADVVQQRRMIDESDADDVHKRVSTAKLDALLGLCESAGCR
RVALLAYFGESSEPCGNCDTCLSPPQTWDATREAQMALSCVYRVQQASRVSFGAGQLIDILRGNATERIKQWHHETLSTF
GIGNALSERAWRGVFRQLVAQGLLAVDHGGHGALVLTDAARPVLKGAQHVTLRRQAEKVRAAPASGAKSERRADPAAELS
AEAQVRWQALRVWRAQTAREHSVPAYVIFHDATLARIAESDPASRDALAELPGIGVAKLDRYGQALLDVLAKCRGEV

Sequences:

>Translated_637_residues
MFDSPAIDHALDALPEDTAAATRAVLHDVFGYSAFRGPQADIVAHVADGGDCLVLMPTGGGKSLCYQIPALVRHRRGQGA
GIVVSPLIALMQDQVAALEEAGVRAAYLNSALSGAEAAQVERDLAAGRLDLVYVAPERLMTPRFLELLERSRIGLFAIDE
AHCVSQWGHDFRPEYIQLSVLHERFPHVPRIALTATADAVTRDEIVERLALGGARVFLSSFDRPNIRYTIVEKDSARQQL
LRFIRAEHLGEDGCDAGIIYCLSRKKVEETAQWLAEQGLRALPYHAGMDAETRARHQAIFRKEEGVVMVATIAFGMGIDK
PDVRFVAHLDLPKSLEGYYQETGRAGRDGLPANAWMAYGLADVVQQRRMIDESDADDVHKRVSTAKLDALLGLCESAGCR
RVALLAYFGESSEPCGNCDTCLSPPQTWDATREAQMALSCVYRVQQASRVSFGAGQLIDILRGNATERIKQWHHETLSTF
GIGNALSERAWRGVFRQLVAQGLLAVDHGGHGALVLTDAARPVLKGAQHVTLRRQAEKVRAAPASGAKSERRADPAAELS
AEAQVRWQALRVWRAQTAREHSVPAYVIFHDATLARIAESDPASRDALAELPGIGVAKLDRYGQALLDVLAKCRGEV
>Mature_637_residues
MFDSPAIDHALDALPEDTAAATRAVLHDVFGYSAFRGPQADIVAHVADGGDCLVLMPTGGGKSLCYQIPALVRHRRGQGA
GIVVSPLIALMQDQVAALEEAGVRAAYLNSALSGAEAAQVERDLAAGRLDLVYVAPERLMTPRFLELLERSRIGLFAIDE
AHCVSQWGHDFRPEYIQLSVLHERFPHVPRIALTATADAVTRDEIVERLALGGARVFLSSFDRPNIRYTIVEKDSARQQL
LRFIRAEHLGEDGCDAGIIYCLSRKKVEETAQWLAEQGLRALPYHAGMDAETRARHQAIFRKEEGVVMVATIAFGMGIDK
PDVRFVAHLDLPKSLEGYYQETGRAGRDGLPANAWMAYGLADVVQQRRMIDESDADDVHKRVSTAKLDALLGLCESAGCR
RVALLAYFGESSEPCGNCDTCLSPPQTWDATREAQMALSCVYRVQQASRVSFGAGQLIDILRGNATERIKQWHHETLSTF
GIGNALSERAWRGVFRQLVAQGLLAVDHGGHGALVLTDAARPVLKGAQHVTLRRQAEKVRAAPASGAKSERRADPAAELS
AEAQVRWQALRVWRAQTAREHSVPAYVIFHDATLARIAESDPASRDALAELPGIGVAKLDRYGQALLDVLAKCRGEV

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=651, Percent_Identity=35.0230414746544, Blast_Score=350, Evalue=2e-96,
Organism=Homo sapiens, GI14591902, Length=414, Percent_Identity=37.43961352657, Blast_Score=286, Evalue=4e-77,
Organism=Homo sapiens, GI14591904, Length=414, Percent_Identity=37.43961352657, Blast_Score=286, Evalue=4e-77,
Organism=Homo sapiens, GI148612816, Length=436, Percent_Identity=39.6788990825688, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI110735439, Length=589, Percent_Identity=32.597623089983, Blast_Score=263, Evalue=4e-70,
Organism=Homo sapiens, GI169218196, Length=505, Percent_Identity=35.4455445544554, Blast_Score=263, Evalue=4e-70,
Organism=Homo sapiens, GI51242947, Length=410, Percent_Identity=39.5121951219512, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI51242943, Length=410, Percent_Identity=39.5121951219512, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI284005309, Length=371, Percent_Identity=35.5795148247978, Blast_Score=195, Evalue=1e-49,
Organism=Escherichia coli, GI48994977, Length=619, Percent_Identity=44.7495961227787, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1788930, Length=324, Percent_Identity=26.2345679012346, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=528, Percent_Identity=36.3636363636364, Blast_Score=318, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI71987997, Length=413, Percent_Identity=39.9515738498789, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI71987993, Length=413, Percent_Identity=39.9515738498789, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI32564293, Length=676, Percent_Identity=30.9171597633136, Blast_Score=291, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17552866, Length=413, Percent_Identity=35.8353510895884, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71987143, Length=339, Percent_Identity=25.0737463126844, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533224, Length=350, Percent_Identity=24, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=558, Percent_Identity=34.2293906810036, Blast_Score=329, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6320224, Length=354, Percent_Identity=20.3389830508475, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320449, Length=336, Percent_Identity=22.6190476190476, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324217, Length=353, Percent_Identity=23.7960339943343, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324778, Length=341, Percent_Identity=24.0469208211144, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646066, Length=639, Percent_Identity=35.3677621283255, Blast_Score=358, Evalue=9e-99,
Organism=Drosophila melanogaster, GI24664226, Length=461, Percent_Identity=36.2255965292842, Blast_Score=262, Evalue=6e-70,
Organism=Drosophila melanogaster, GI62472181, Length=458, Percent_Identity=36.6812227074236, Blast_Score=259, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24664230, Length=458, Percent_Identity=36.6812227074236, Blast_Score=258, Evalue=9e-69,
Organism=Drosophila melanogaster, GI21358123, Length=378, Percent_Identity=35.7142857142857, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI28574962, Length=329, Percent_Identity=27.355623100304, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI18857967, Length=376, Percent_Identity=24.2021276595745, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 69518; Mature: 69518

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSPAIDHALDALPEDTAAATRAVLHDVFGYSAFRGPQADIVAHVADGGDCLVLMPTGG
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCC
GKSLCYQIPALVRHRRGQGAGIVVSPLIALMQDQVAALEEAGVRAAYLNSALSGAEAAQV
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHH
ERDLAAGRLDLVYVAPERLMTPRFLELLERSRIGLFAIDEAHCVSQWGHDFRPEYIQLSV
HHHHHCCCEEEEEECHHHHCCHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCHHHHHH
LHERFPHVPRIALTATADAVTRDEIVERLALGGARVFLSSFDRPNIRYTIVEKDSARQQL
HHHHCCCCCCEEEEECHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEEEEECCHHHHHH
LRFIRAEHLGEDGCDAGIIYCLSRKKVEETAQWLAEQGLRALPYHAGMDAETRARHQAIF
HHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
RKEEGVVMVATIAFGMGIDKPDVRFVAHLDLPKSLEGYYQETGRAGRDGLPANAWMAYGL
HCCCCEEEEEEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ADVVQQRRMIDESDADDVHKRVSTAKLDALLGLCESAGCRRVALLAYFGESSEPCGNCDT
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCC
CLSPPQTWDATREAQMALSCVYRVQQASRVSFGAGQLIDILRGNATERIKQWHHETLSTF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
GIGNALSERAWRGVFRQLVAQGLLAVDHGGHGALVLTDAARPVLKGAQHVTLRRQAEKVR
CCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHHCCCHHHHHHHHHHHHH
AAPASGAKSERRADPAAELSAEAQVRWQALRVWRAQTAREHSVPAYVIFHDATLARIAES
CCCCCCCCHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCC
DPASRDALAELPGIGVAKLDRYGQALLDVLAKCRGEV
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFDSPAIDHALDALPEDTAAATRAVLHDVFGYSAFRGPQADIVAHVADGGDCLVLMPTGG
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCC
GKSLCYQIPALVRHRRGQGAGIVVSPLIALMQDQVAALEEAGVRAAYLNSALSGAEAAQV
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHH
ERDLAAGRLDLVYVAPERLMTPRFLELLERSRIGLFAIDEAHCVSQWGHDFRPEYIQLSV
HHHHHCCCEEEEEECHHHHCCHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCHHHHHH
LHERFPHVPRIALTATADAVTRDEIVERLALGGARVFLSSFDRPNIRYTIVEKDSARQQL
HHHHCCCCCCEEEEECHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEEEEECCHHHHHH
LRFIRAEHLGEDGCDAGIIYCLSRKKVEETAQWLAEQGLRALPYHAGMDAETRARHQAIF
HHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
RKEEGVVMVATIAFGMGIDKPDVRFVAHLDLPKSLEGYYQETGRAGRDGLPANAWMAYGL
HCCCCEEEEEEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ADVVQQRRMIDESDADDVHKRVSTAKLDALLGLCESAGCRRVALLAYFGESSEPCGNCDT
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCC
CLSPPQTWDATREAQMALSCVYRVQQASRVSFGAGQLIDILRGNATERIKQWHHETLSTF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
GIGNALSERAWRGVFRQLVAQGLLAVDHGGHGALVLTDAARPVLKGAQHVTLRRQAEKVR
CCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHHCCCHHHHHHHHHHHHH
AAPASGAKSERRADPAAELSAEAQVRWQALRVWRAQTAREHSVPAYVIFHDATLARIAES
CCCCCCCCHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCC
DPASRDALAELPGIGVAKLDRYGQALLDVLAKCRGEV
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]